CDC42
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Homo sapiens |
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CDC42 is differentially expressed in 325 experiments: 167 organism parts: kidney, liver, ... (165 more);, 260 disease states: normal, breast carcinoma, ... (258 more);, 106 cell types 466 cell lines 36 compound treatments and 78 other conditions. |
| Synonyms |
CDC42Hs, G25K |
| Orthologs |
CDC42
(Saccharomyces cerevisiae)
CDC42_CHICK
(Gallus gallus)
F6R1X5_CIOIN
(Ciona intestinalis)
ENSCING00000016916
(Ciona intestinalis)
Cdc42
(Rattus norvegicus)
cdc42
(Danio rerio)
F1MND1_BOVIN
(Bos taurus)
Cdc42
(Mus musculus)
Cdc42
(Drosophila melanogaster)
cdc42
(Xenopus laevis)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, spindle midzone, plasma membrane, cell division, negative regulation of epidermal growth factor receptor signaling pathway, stored secretory granule, GTPase activity, establishment or maintenance of cell polarity, adherens junction organization, protein binding, regulation of mitosis, regulation of protein catabolic process, cytoskeleton, cytoplasm, cell-cell adhesion, actin filament bundle assembly, epidermal growth factor receptor signaling pathway, intracellular, positive regulation of gene expression, membrane, establishment or maintenance of apical/basal cell polarity, Golgi membrane, epidermis morphogenesis, regulation of protein stability, regulation of protein kinase activity, nucleus localization, blood coagulation, nuclear migration, keratinization, positive regulation of JNK cascade, GTP catabolic process, multicellular organism growth, GTP binding, filopodium, actin cytoskeleton organization, axon guidance, regulation of protein metabolic process, small GTPase mediated signal transduction, midbody, microtubule organizing center, muscle cell differentiation, cell projection, filopodium assembly, regulation of small GTPase mediated signal transduction, canonical Wnt receptor signaling pathway, positive regulation of DNA replication, regulation of filopodium assembly, nucleotide binding, nervous system development, apical part of cell, negative regulation of gene expression, signal transduction, protein transport, GTP-dependent protein binding, epithelial cell-cell adhesion, positive regulation of peptidyl-serine phosphorylation, positive regulation of hair follicle cell proliferation, epithelial-mesenchymal cell signaling, hair follicle morphogenesis, positive regulation of pseudopodium assembly, neuron fate determination, regulation of protein heterodimerization activity, cellular protein localization, hair follicle placode formation, thioesterase binding, macrophage differentiation, keratinocyte development, T cell costimulation, positive regulation of MAPKKK cascade, positive regulation of muscle cell differentiation, regulation of attachment of spindle microtubules to kinetochore, mitogen-activated protein kinase kinase kinase binding, negative regulation of protein complex assembly, positive regulation of protein phosphorylation, cell periphery, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of cell cycle cytokinesis, mitotic spindle |
| Gene Ontology ID |
GO:0010629, GO:0010628, GO:0016020, GO:0015031, GO:0060070, GO:0003924, GO:0007097, GO:0007088, GO:0007173, GO:0007163, GO:0007165, GO:0007264, GO:0016337, GO:0007399, GO:0007411, GO:0051246, GO:0007596, GO:0051233, GO:0048730, GO:0051301, GO:0030496, GO:0051017, GO:0051056, GO:0042692, GO:0005622, GO:0005525, GO:0005515, GO:0005737, GO:0005886, GO:0005856, GO:0005829, GO:0005815, GO:0042995, GO:0046330, GO:0001934, GO:0000166, GO:0045740, GO:0000139, GO:0031647, GO:0046847, GO:0042176, GO:0042059, GO:0006184, GO:0051489, GO:0031424, GO:0051647, GO:0045859, GO:0030141, GO:0030175, GO:0030036, GO:0045177, GO:0034332, GO:0035088, GO:0035264, GO:0060684, GO:0031996, GO:0030742, GO:0051149, GO:0048664, GO:0003334, GO:0031274, GO:0031295, GO:0031333, GO:0051988, GO:0090136, GO:0031069, GO:0043552, GO:0031435, GO:0043497, GO:0043410, GO:0071338, GO:0060789, GO:0030225, GO:0033138, GO:0034613, GO:0071944, GO:0071777, GO:0072686 |
| InterPro ID |
IPR006689, IPR005225, IPR001806, IPR013684, IPR003578, IPR003579, IPR020849 |
| InterPro Term |
MIRO-like, Small_GTPase, Small_GTP-bd_dom, Small_GTPase_ARF/SAR, Small_GTPase_Ras, Small_GTPase_Rho, Small_GTPase_Rab_type |
| Ensembl Protein ID |
ENSP00000398327, ENSP00000398592, ENSP00000383118, ENSP00000314458, ENSP00000341072 |
| RefSeq ID |
NP_426359, NP_001034891, NP_001782, NM_001791, NM_044472, NM_001039802 |
| UniProt Accession |
Q5JYX0, Q9UJM0, Q9UJM1, P60953, E7ETU3 |
| Description |
cell division cycle 42 (GTP binding protein, 25kDa) [Source:HGNC Symbol;Acc:1736] |
| UniGene ID |
Hs.467637, Hs.720458 |
| EMBL-Bank ID |
M35543, BC002711, AY673602, AL121734, AL121735, AL121736, AL121737, M57298, AF498963, BC003682, AF498962, AL031281, BC018266 |
| Ensembl Gene ID |
ENSG00000070831 |
| HGNC Symbol |
CDC42 |
| Entrez Gene ID |
998 |
| Ensembl Family |
ENSFM00630001050535 |
| Ensembl Family Description |
CELL DIVISION CONTROL 42 HOMOLOG PRECURSOR |
| Ensembl Transcript ID |
ENST00000411827, ENST00000315554, ENST00000400259, ENST00000421089, ENST00000498236, ENST00000344548 |
| Design Element |
Hs.146409.3.S1_3p_at, g13277547_3p_s_at, ENST00000411827, g12803746_3p_a_at, ENST00000400259, 210232_at, 208728_s_at, 959_at, ENST00000498236, 208728_3p_s_at, g182856_3p_at, 39736_at, ENST00000315554, ENST00000421089, 214230_at, 208727_s_at, ENST00000344548, 960_g_at, g13277547_3p_at |
| Search EB-eye |
ENSG00000070831
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