PKM2
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Homo sapiens |
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PKM2 is differentially expressed in 280 experiments: 105 organism parts: liver, skeletal muscle, ... (103 more);, 184 disease states: normal, breast carcinoma, ... (182 more);, 96 cell types 242 cell lines 31 compound treatments and 73 other conditions. |
| Synonyms |
PK3, THBP1, OIP3 |
| Orthologs |
Pkm2
(Rattus norvegicus)
pkm2b
(Danio rerio)
F1P4U1_CHICK
(Gallus gallus)
Pkm2
(Mus musculus)
A5D984_BOVIN
(Bos taurus)
CDC19
(Saccharomyces cerevisiae)
F6UHT5_CIOIN
(Ciona intestinalis)
pkm2a
(Danio rerio)
PYK2
(Saccharomyces cerevisiae)
CG7362
(Drosophila melanogaster)
CG7069
(Drosophila melanogaster)
CG2964
(Drosophila melanogaster)
PyK
(Drosophila melanogaster)
pkm2
(Xenopus laevis)
O62755_CANFA
(Canis familiaris)
(Compare orthologs)
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| Ensembl Family Description |
PYRUVATE KINASE EC_2.7.1.40 |
| InterPro ID |
IPR001697, IPR015795, IPR015793 |
| Gene Ontology Term |
cytosol, plasma membrane, glucose metabolic process, protein binding, flagellum, cytoplasm, response to hypoxia, soluble fraction, glycolysis, programmed cell death, response to nutrient, pyruvate kinase activity, ATP binding, magnesium ion binding, potassium ion binding, nucleus, nucleotide binding, carbohydrate metabolic process, ATP biosynthetic process, transferase activity, response to gravity, mitochondrion, pyruvate biosynthetic process, ADP binding, skeletal muscle tissue regeneration, organ regeneration, response to insulin stimulus, liver development, response to organic substance, response to muscle inactivity |
| InterPro Term |
Pyr_Knase, Pyrv_Knase_brl, Pyrv_Knase_C |
| Gene Ontology ID |
GO:0009629, GO:0005975, GO:0007584, GO:0016740, GO:0004743, GO:0005625, GO:0005524, GO:0005515, GO:0012501, GO:0005737, GO:0005739, GO:0005634, GO:0030955, GO:0005886, GO:0005829, GO:0006754, GO:0019861, GO:0000166, GO:0000287, GO:0006096, GO:0001666, GO:0006006, GO:0010033, GO:0042866, GO:0031100, GO:0032868, GO:0014870, GO:0001889, GO:0043531, GO:0043403 |
| Ensembl Family |
ENSFM00250000000989 |
| UniGene ID |
Hs.534770, Hs.711246, Hs.610382 |
| UniProt Accession |
Q8WUW7, Q9UKK4, P14618, B4DNK4, B4DUU6, E7EUJ4, E7EUQ8, E9PF79 |
| EMBL-Bank ID |
AC020779, BC019265, M26252, X56494, AF025439, BC012811, AK297951, BC035198, AK312253, BC007640, CH471082, AK092369, BC000481, AK294315, AF157692, AK300800, M23725, AK222927, BC007952, AY352517 |
| Ensembl Protein ID |
ENSP00000334983, ENSP00000403365, ENSP00000413887, ENSP00000369278, ENSP00000373745, ENSP00000320171 |
| HGNC Symbol |
PKM2 |
| RefSeq ID |
NP_872271, NP_872270, NM_182471, NM_182470, NP_002645, NM_002654, NP_001193725, NP_001193726, NP_001193727, NP_001193728, NM_001206798, NM_001206797, NM_001206796, NM_001206799 |
| Description |
pyruvate kinase, muscle [Source:HGNC Symbol;Acc:9021] |
| Ensembl Gene ID |
ENSG00000067225 |
| Entrez Gene ID |
5315 |
| Ensembl Transcript ID |
ENST00000327974, ENST00000449901, ENST00000434220, ENST00000389093, ENST00000335181, ENST00000319622 |
| Design Element |
201251_at, ENST00000449901, g4505838_3p_x_at, ENST00000319622, ENST00000434220, X56494_at, ENST00000389093, g4505838_3p_at, ENST00000327974, 32378_at, ENST00000335181 |
| Search EB-eye |
ENSG00000067225
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