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SPI1 Homo sapiens
SPI1 is differentially expressed in 76 experiments [81 up/76 dn]: 17 organism parts: kidney [1 up/1 dn], whole blood [1 up/0 dn], ...; 18 disease states: normal [2 up/7 dn], glioblastoma [3 up/0 dn], ...; 27 cell types, 27 cell lines, 13 compound treatments and 17 other conditions.
Synonyms SPI1
Orthologs spi1 (Danio rerio)  Sfpi1 (Mus musculus)  (Compare orthologs)
InterPro Term Ets, Winged helix-turn-helix transcription repressor DNA-binding
GO Terms RNA binding, negative regulation of transcription from RNA polymerase II promoter, nucleus, protein binding, sequence-specific DNA binding
Uniprot P17947 
Search EB-eye ENSG00000066336
REST API
Expression Summary
139 factor values, click each to filter
Factor Value Factor Up/Down
Legend: - number of studies the gene is up/down in
Normal Disease state
7
2
Glioblastoma Disease state
3
None Compound treatment
2
1
FLAP Compound treatment
2
HNRPA2B Compound treatment
2
MK886 Compound treatment
2
Invasive ductal carcinoma Histology
2
MCF-7 Cell line
1
1
Kidney Organism part
1
1
HL-60 Cell line
1
SW480 Cell line
1
SW620 Cell line
1
Bacterial endotoxin Compound treatment
1
Control Compound treatment
1
MCF7 Cell line
1
PC3 Cell line
1
SKMEL5 Cell line
1
T cell Cell type
1
Peripheral blood mononuclear c... Cell type
1
Grade IV Tumor grading
1
Whole blood Organism part
1
Primary gastric tumor Organism part
1
BJAB Cell line
1
HPL1 Cell line
1
Plasmacytoid dendritic cell Cell type
1
MDA-MB-231 Cell line
1
Spermatid Cell type
1
Vascular smooth muscle cell Cell type
1
Caudate nucleus Organism part
1
HeLa Cell line
1
Chondrocyte Cell type
1
KSHV-negative EBV-positive Clinical info
1
Pancreas Organism part
1
Acute lymphocytic leukemia Disease state
1
Spleen Organism part
1
Heart Organism part
1
Chronic lymphocytic leukemia Disease state
1
Pretreatment primary sample Clinical info
1
SsMCF7 Cell line
1
Frontal cortex, primary motor ... Organism part
1
IgV status unknown Genotype
1
Unknown_sex Sex
1
Lung Organism part
1
N/a Test result
1
Bone marrow Organism part
1
White blood cell Cell type
1
Platelet Cell type
1
Testis Organism part
1
BCKN-1 Cell line
1
Ductal carcinoma in situ Disease state
1
Invasive ductal carcinoma Disease state
1
IgV mutated Genotype
1
Trichostatin A Compound treatment
1
Epilepsy Disease state
1
Primary Disease staging
1
CD16+ dendritic cell Cell type
1
293 Cell line
1
Native skin Cell type
1
Breast carcinoma Disease state
1
Primary bone marrow CD34+ stem... Cell type
1
HaCaT Cell line
1
CodeLink Labeling Protocol type
1
Acute promyelocytic leukemia Disease state
1
U937 Cell line
1
Drug-naive Clinical treatment
1
Seminiferous tubule Organism part
1
Skeletal muscle Organism part
1
CD8+ T cell Cell type
1
HMEC184 Cell line
1
Glucocorticoid resistant Phenotype
1
Baseline uninfected Disease state
1
Cartilage Organism part
1
Not applicable Histology
1
Fibroblast Cell type
1
Endothelial cell Cell type
1
KSHV-positive EBV-negative Clinical info
1
Peripheral blood Organism part
1
Total_RNA Material type
1
Polysome-associated RNA Material type
1
Hematopoietic stem cell Cell type
1
Adipose tissue-derived stem ce... Cell type
1
SM1 Cell line
1
0 cm away from the tumor bound... Observation
1
Diagnosed with skin cancer bef... Clinical history
1
Female Sex
1
Skin Organism part
1
Fetal bovine serum in media Growth condition
1
Brain Organism part
1
Ulcerative colitis Disease state
1
Viral load medium Clinical history
1
X-linked chronic granulomatous Disease state
1
Superficial transitional cell ... Disease state
1
BC-2 Cell line
1
MCF10A Cell line
1
CD34+ Cell type
1
Homo sapiens Organism
1
Spermatocyte Cell type
1
Macaca mulatta Organism
1
Osteoblast Cell type
1
Endometrioid carcinoma Disease state
1
Control RNAi
1
SIM2s RNAi
1
Cyclosporin A, mycophenolate m... Clinical treatment
1
Sirolimus, mycophenolate mofet... Clinical treatment
1
1,10-phenanthroline Compound treatment
1
Lung adenocarcinoma Disease state
1
PEL-5 Cell line
1
Muscle invasive carcinoma Disease state
1
Sham surgery Clinical treatment
1
CD19+ B cells (neg. sel.) Cell type
1
Granulocyte-colony stimulating... Compound treatment
1
Estrogen receptor 1 positive; ... Test result
1
Male Sex
1
HMEC S1 Cell line
1
Affymetrix Labeling Protocol type
1
IBL4 Cell line
1
Pan troglodytes Organism
1
Limited radiation toxicity Clinical history
1
Papillary thyroid carcinoma Disease state
1
T47-D Cell line
1
CD3+ CD4+ CD8- CD45RA+ CD62L+ Phenotype
1
Naive T cell Cell type
1
Adipose-derived stem cell Cell type
1
MS589 Cell line
1
Rapamycin Compound treatment
1
Vanadium pentoxide Compound treatment
1
Estrogen receptor 1 positive; ... Test result
1
Monocyte Cell type
1
Epithelial cell Cell type
1
Stromal cell Cell type
1
BT-474 Cell line
1
ITM-E6E7-ST Cell line
1
R-(-)-apomorphine HCl Compound treatment
1
Training set Population
1
Test set Population
1
Stimulated polymorphonuclear l... Cell type
1
Unstimulated polymorphonuclear... Cell type
1
Hydrogen peroxide Compound treatment
1
Non-ischemic cardiomyopathy Disease state
1
Expression Profiles
E-GEOD-5258: Transcription profiling of human cell lines freely cycling treated with 164 distinct small molecules - Broad Connectivity Map CMAP Set 1
Experimental Factors
Show expression profile  /  experiment details

 
E-MEXP-1014: Transcription profiling of two human colon cancer cell lines treated with n-3 PUFA docosahexaenoic acid for 3 different time points
Experimental Factors
Show expression profile  /  experiment details

 
E-GEOD-3284: Transcription profiling of human leukocytes after an inflammatory stimulus (bacterial endotoxin) to identify significant functional modules perturbed in response to this stimulus using network analysis
Experimental Factors
Time Individual Compound treatment
Show expression profile  /  experiment details

 
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