SPI1
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Homo sapiens |
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SPI1 is differentially expressed in 197 experiments: 63 organism parts: lung, bone marrow, ... (61 more);, 205 disease states: normal, glioblastoma, ... (203 more);, 73 cell types 185 cell lines 23 compound treatments and 59 other conditions. |
| Synonyms |
SFPI1, SPI-A, SPI-1, PU.1, OF |
| Orthologs |
E1BJR2_BOVIN
(Bos taurus)
Sfpi1
(Mus musculus)
spi1
(Danio rerio)
spi1l
(Danio rerio)
E1BZN0_CHICK
(Gallus gallus)
Spi1
(Rattus norvegicus)
spi1
(Xenopus laevis)
SPI1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0003677, GO:0003723, GO:0003700, GO:0005515, GO:0006917, GO:0005634, GO:0000790, GO:0000122, GO:0006355, GO:0006357, GO:0006351, GO:0043565, GO:0045893, GO:0035019, GO:0060033, GO:0002573, GO:0002320, GO:0030851, GO:0001944, GO:0043011, GO:0045646, GO:0030098, GO:0030225, GO:0045347, GO:0030218, GO:0001085 |
| Gene Ontology Term |
DNA binding, protein binding, regulation of transcription, DNA-dependent, nuclear chromatin, transcription, DNA-dependent, sequence-specific DNA binding, induction of apoptosis, nucleus, somatic stem cell maintenance, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, RNA binding, myeloid leukocyte differentiation, negative regulation of MHC class II biosynthetic process, regulation of erythrocyte differentiation, granulocyte differentiation, erythrocyte differentiation, lymphocyte differentiation, lymphoid progenitor cell differentiation, vasculature development, anatomical structure regression, myeloid dendritic cell differentiation, macrophage differentiation, sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding |
| InterPro ID |
IPR000418 |
| InterPro Term |
Ets |
| Ensembl Family Description |
TRANSCRIPTION FACTOR PU 1 |
| Ensembl Family |
ENSFM00500000271550 |
| Ensembl Protein ID |
ENSP00000367799, ENSP00000227163, ENSP00000438846, ENSP00000443865 |
| EMBL-Bank ID |
X52056, AC090582, AC090559, AL532058 |
| RefSeq ID |
NM_003120, NM_001080547, NP_003111, NP_001074016 |
| Ensembl Gene ID |
ENSG00000066336 |
| Description |
spleen focus forming virus (SFFV) proviral integration oncogene spi1 [Source:HGNC Symbol;Acc:11241] |
| Entrez Gene ID |
6688 |
| HGNC Symbol |
SPI1 |
| UniProt Accession |
P17947, F5GZ94, F5H3K6 |
| UniGene ID |
Hs.502511 |
| Ensembl Transcript ID |
ENST00000227163, ENST00000378538, ENST00000533968, ENST00000533030 |
| Design Element |
ENST00000533030, 205312_at, ENST00000378538, ENST00000533968, ENST00000227163, 1341_at, g4507174_3p_at, X52056_at |
| Search EB-eye |
ENSG00000066336
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