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PDCD6 Homo sapiens
PDCD6 is differentially expressed in 118 experiments [135 up/130 dn]: 34 organism parts: skin [2 up/0 dn], bone marrow [0 up/2 dn], ...; 34 disease states: normal [1 up/8 dn], breast carcinoma [2 up/0 dn], ...; 28 cell types, 28 cell lines, 19 compound treatments and 21 other conditions.
Synonyms ALG2, PDCD6, hCG_1985580
Orthologs AHRR_RAT (Rattus norvegicus)  ss (Drosophila melanogaster)  Ahrr (Mus musculus)  (Compare orthologs)
InterPro Term EF-HAND 2, EF-Hand 1, calcium-binding site, EF-hand-like domain, Calcium-binding EF-hand
GO Terms apoptosis, calcium ion binding, calcium-dependent protein binding, extrinsic to membrane, molecular adaptor activity
Uniprot O75340  Q2YDC2  Q53FC3  Q86W51 
Search EB-eye ENSG00000063438
REST API
Expression Summary
223 factor values, click each to filter
Factor Value Factor Up/Down
Legend: - number of studies the gene is up/down in
Normal Disease state
8
1
None Compound treatment
2
3
Epithelial cell Cell type
1
2
Stromal cell Cell type
1
2
Uninfected Infection
3
Skin Organism part
2
FLAP Compound treatment
2
HNRPA2B Compound treatment
2
Invasive ductal carcinoma Histology
2
MK886 Compound treatment
2
N/a Test result
2
Breast carcinoma Disease state
2
Not applicable Histology
2
HL-60 Cell line
1
1
0 cm away from the tumor bound... Observation
2
Acute promyelocytic leukemia Disease state
2
Endothelial cell Cell type
2
Estrogen receptor 1 positive; ... Test result
2
Caco-2 Cell line
2
MDA-MB-231 Cell line
1
1
HeLa Cell line
2
BT-474 Cell line
1
1
Monocyte Cell type
1
1
Bone marrow Organism part
2
Acute myeloid leukemia Disease state
2
Control Compound treatment
2
Homo sapiens Organism
1
1
Skeletal muscle Organism part
1
1
Cerebellum Organism part
1
1
SW480 Cell line
1
SW620 Cell line
1
Primary gastric tumor Organism part
1
Pretreatment primary sample Clinical info
1
Frontal cortex, superior motor... Organism part
1
Glucocorticoid sensitive Phenotype
1
BT474 Cell line
1
U87 Cell line
1
U373 Cell line
1
Glucocorticoid resistant Phenotype
1
Lymphatic endothelial cell Cell type
1
Caudate nucleus Organism part
1
Epilepsy Disease state
1
Vascular smooth muscle cell Cell type
1
Chondrocyte Cell type
1
M1 macrophage Cell type
1
Interferon-gamma + lipopolysac... Compound treatment
1
MCF-7 Cell line
1
Enzo Labeling Protocol type
1
Methotrexate Compound treatment
1
Spermatocyte Cell type
1
Acute radiation toxicity Clinical history
1
Plasma cell Cell type
1
B lymphocyte Cell type
1
Fetal bovine serum in media Growth condition
1
Epidermal keratinocyte Cell type
1
SkinEthic keratinocyte Cell type
1
Rapamycin Compound treatment
1
U937 Cell line
1
Stage II Disease staging
1
Cervical cancer Disease state
1
Appendix Organism part
1
Johnsen score count 3.2: Serto... Histology
1
Testis Organism part
1
T3aNxM1 Disease staging
1
Lipopolysaccharide Compound treatment
1
Kaposi's sarcoma-associated he... Infection
1
MDA468 Cell line
1
ATM knockdown RNAi
1
CodeLink Labeling Protocol type
1
Seminiferous tubule Organism part
1
Uterine cervix Organism part
1
Prostate Organism part
1
HTERT/HPVE6/HPVE7/SV40t/hRas t... Gene modification
1
BL41K3 Cell line
1
BJABK3 Cell line
1
Spermatid Cell type
1
Dimethyl sulfoxide Compound treatment
1
Cartilage Organism part
1
Pan troglodytes Organism
1
White blood cells Organism part
1
Fibroblast Cell type
1
Oligodendroglioma Disease state
1
T3aNxMx Disease staging
1
HPL1 Cell line
1
T84 Cell line
1
Actinomycin D Compound treatment
1
HaCaT Cell line
1
Heat-killed HL60 cell lysate Infection
1
SsMCF7 Cell line
1
Spleen Organism part
1
Chronic myelogenous leukemia Disease state
1
T-cell acute lymphoblastic leu... Disease state
1
ERalpha transfected Genotype
1
ERbeta transfected Genotype
1
MCF7 Cell line
1
Benign prostatic hyperplasia Disease state
1
Prostate carcinoma Disease state
1
Primary cells Cell line
1
PC3 Cell line
1
Astrocyte Cell type
1
Lung adenocarcinoma Disease state
1
Serum starvation synchronizati... Growth condition
1
Superficial transitional cell ... Disease state
1
5-aza-2'-deoxycytidine + trich... Compound treatment
1
Macaca mulatta Organism
1
Johnsen score count 7: many ea... Histology
1
Adenocarcinoma Disease state
1
Johnsen score count 2: Sertoli... Histology
1
LacZ control RNAi
1
Carcinoma in situ lesion Disease state
1
Ovary Organism part
1
Native skin Cell type
1
B-precursor acute lymphoblasti... Disease state
1
Osteoblast Cell type
1
Synovial fluid Organism part
1
Peripheral blood Organism part
1
M2 macrophage Cell type
1
Trichostatin A Compound treatment
1
Metastatic Disease staging
1
ITS medium Growth condition
1
Inter-prandial lipid micelles ... Growth condition
1
ITS medium with albumin-bound ... Growth condition
1
Postprandial lipid micelles in... Growth condition
1
None Gene modification
1
Superior cervical ganglion Organism part
1
Endometrioid carcinoma Disease state
1
Tumor Organism part
1
HTERT/HPVE6/HPVE7/SV40t transf... Gene modification
1
IL-4 Compound treatment
1
Stage I Disease staging
1
Whole brain Organism part
1
Ultrafine particles Compound treatment
1
Pan paniscus Organism
1
Umbilical cord Organism part
1
Adult Developmental stage
1
Infant Developmental stage
1
Beas2B Cell line
1
Well-functioning transplant Clinical info
1
Measles virus Chicago-1 strain Infection
1
Serum starvation + thymidine b... Growth condition
1
Grade II Tumor grading
1
Idiopathic dilated cardiomyopa... Disease state
1
Met5A Cell line
1
Aggregatibacter actinomycetemc... Infection
1
Wild_type Genotype
1
Amygdala Organism part
1
Subthalamic nucleus Organism part
1
Control RNAi
1
SIM2s RNAi
1
X-linked chronic granulomatous Disease state
1
HTERT/HPVE6 transfection Gene modification
1
Fetal liver Organism part
1
Pancreas Organism part
1
Glioblastoma Disease state
1
Organism_part Material type
1
Cell Material type
1
Gastric cancer Disease state
1
Hypericin incubated, not irrad... Growth condition
1
Hypericin incubated, irradiate... Growth condition
1
Dendritic cell Cell type
1
Ethanol Vehicle
1
Multiple myeloma Disease state
1
T4aN0M0 Disease staging
1
Empty adenovirus Gene modification
1
Ischemic cardiomyopathy Disease state
1
Estrogen receptor 1 positive; ... Test result
1
Grade IV Tumor grading
1
Duodenum Organism part
1
BJAB Cell line
1
Beta cell islets Organism part
1
Lung Organism part
1
Plasma cell leukemia Disease state
1
Right parietal occipital Organism part
1
Superficial transitional cell ... Disease state
1
Mannitol Compound treatment
1
Jurkat Cell line
1
Monocyte at intermediate diffe... Cell type
1
Gastric adenocarcinoma Disease state
1
Heart Organism part
1
Normal Clinical history
1
MDS-associated acute myeloid l... Disease state
1
Muscle invasive carcinoma Disease state
1
CXCR5(hi)ICOS(hi) CD4 T cell Target cell type
1
Fetal thyroid Organism part
1
MCF10A Cell line
1
CD3int CD4+ CD8+ Phenotype
1
Double positive thymocyte Cell type
1
Lymph node Organism part
1
Tonsil Organism part
1
CD3high CD4+ CD8- Phenotype
1
Single positive thymocyte Cell type
1
Drug regimen not indicated Clinical treatment
1
Smoker Clinical info
1
Non-smoker Clinical info
1
DMSO Vehicle
1
Carboplatin resistant Test result
1
Carboplatin sensitive Test result
1
Breast cancer Disease state
1
Chronic lymphocytic leukemia Disease state
1
Benign Disease staging
1
Basal cell Cell type
1
Training set Population
1
Test set Population
1
Normal donor Clinical info
1
Keratinocyte Cell type
1
Secretory cell Cell type
1
Vasectomized Clinical history
1
Affymetrix Labeling Protocol type
1
Acute lymphocytic leukemia Disease state
1
Growth medium Vehicle
1
Monoclonal gammopathy of undet... Disease state
1
Primary Disease staging
1
Lymph node metastasis Disease staging
1
White blood cell Cell type
1
Platelet Cell type
1
KSHV latent infection Disease state
1
PCep4 control vector transfect... Gene modification
1
ETat plasmid transfection Gene modification
1
Pergolide methanesulfonate Compound treatment
1
Bacterial endotoxin Compound treatment
1
Pick's disease Disease state
1
Placebo Compound treatment
1
MKN1 Cell line
1
Expression Profiles
E-MEXP-2034: Transcription profiling of human primary prostate epithelial and stromal cells exposed to 4-methylsulphinylbutyl and 3-methylsulphinypropyl isothiocyanates
Experimental Factors
Show expression profile  /  experiment details

 
E-MEXP-1014: Transcription profiling of two human colon cancer cell lines treated with n-3 PUFA docosahexaenoic acid for 3 different time points
Experimental Factors
Show expression profile  /  experiment details

 
E-GEOD-4646: Transcription profiling of human HUVEC cells infected with Neisseria meningitidis wild type and mutants vs uninfected sampled at 3 time points
Experimental Factors
Time Infection
Show expression profile  /  experiment details

 
E-GEOD-15460: Transcription profiling of human gastric cancers, cell lines and controls
Experimental Factors
Show expression profile  /  experiment details

 
E-GEOD-5824: Transcription profiling of human Acute Lymphoblastic Leukemia CEM_C1 cells treated with rapamycin identifies rapamycin as a glucocorticoid resistance reversal agent
Experimental Factors
Phenotype Time Clinical info Dose Compound treatment
Show expression profile  /  experiment details

 
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