FOXP3
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Homo sapiens |
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FOXP3 is differentially expressed in 156 experiments: 82 organism parts: lung, prostate, ... (80 more);, 141 disease states: normal, breast carcinoma, ... (139 more);, 55 cell types 165 cell lines 19 compound treatments and 71 other conditions. |
| Synonyms |
DIETER, IPEX, XPID, PIDX, JM2, AIID, SCURFIN |
| Orthologs |
FKH2
(Saccharomyces cerevisiae)
Foxp3
(Mus musculus)
FOXP3
(Bos taurus)
foxp3b
(Danio rerio)
FKH1
(Saccharomyces cerevisiae)
Foxp3
(Rattus norvegicus)
FOXP3
(Xenopus laevis)
FOXP3
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
pattern specification process, embryo development, negative regulation of transcription, DNA-dependent, protein binding, regulation of transcription, DNA-dependent, cytoplasm, double-stranded DNA binding, intracellular, negative regulation of cell proliferation, protein complex, transcription, DNA-dependent, transcription corepressor activity, metal ion binding, DNA bending activity, histone deacetylase binding, sequence-specific DNA binding, positive regulation of transcription from RNA polymerase II promoter, positive regulation of histone acetylation, nucleus, protein heterodimerization activity, chromatin remodeling, transcription factor complex, post-embryonic development, histone acetyltransferase binding, chromatin binding, protein homodimerization activity, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, zinc ion binding, T cell receptor signaling pathway, myeloid cell homeostasis, negative regulation of interferon-gamma biosynthetic process, regulation of isotype switching to IgG isotypes, negative regulation of NF-kappaB transcription factor activity, positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation, cerebellum development, negative regulation of CREB transcription factor activity, negative regulation of histone acetylation, regulation of immunoglobulin production, positive regulation of regulatory T cell differentiation, tolerance induction, T cell activation, negative regulation of interleukin-2 production, negative regulation of cytokine secretion, response to virus, negative regulation of interleukin-5 production, B cell homeostasis, negative regulation of interferon-gamma production, negative regulation of inflammatory response, negative regulation of interleukin-10 production, negative regulation of interleukin-4 production, negative regulation of activated T cell proliferation, CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation, negative regulation of interleukin-6 production, NF-kappaB binding, T cell homeostasis, positive regulation of T cell tolerance induction, negative regulation of cytokine biosynthetic process, negative regulation of tumor necrosis factor production, negative regulation of interleukin-2 biosynthetic process, regulatory T cell differentiation, negative regulation of lymphocyte proliferation, negative regulation of chronic inflammatory response, positive regulation of peripheral T cell tolerance induction, negative regulation of isotype switching to IgE isotypes, tolerance induction to self antigen, positive regulation of T cell anergy, cytokine production, negative regulation of T cell proliferation, negative regulation of immune response, T cell mediated immunity, sequence-specific DNA binding transcription factor activity, negative regulation of T cell cytokine production, NFAT protein binding, negative regulation of histone deacetylation, negative regulation of sequence-specific DNA binding transcription factor activity, positive regulation of immature T cell proliferation in thymus, positive regulation of transforming growth factor beta1 production, sequence-specific distal enhancer binding RNA polymerase II transcription factor activity |
| Gene Ontology ID |
GO:0003682, GO:0003690, GO:0008285, GO:0008270, GO:0008301, GO:0003714, GO:0003700, GO:0003705, GO:0009791, GO:0009790, GO:0007389, GO:0042803, GO:0005622, GO:0005515, GO:0005737, GO:0005634, GO:0005667, GO:0042826, GO:0000122, GO:0006338, GO:0046872, GO:0006355, GO:0006357, GO:0006351, GO:0046982, GO:0043234, GO:0045944, GO:0043565, GO:0045892, GO:0045893, GO:0043433, GO:0035035, GO:0035066, GO:0009615, GO:0002851, GO:0002637, GO:0002669, GO:0002666, GO:0002677, GO:0051059, GO:0002507, GO:0002513, GO:0046007, GO:0002456, GO:0048302, GO:0002361, GO:0048294, GO:0002262, GO:0050672, GO:0050777, GO:0050728, GO:0050710, GO:0032693, GO:0032689, GO:0032703, GO:0032714, GO:0032713, GO:0032715, GO:0032720, GO:0050852, GO:0043029, GO:0032792, GO:0032831, GO:0001782, GO:0042130, GO:0042110, GO:0032914, GO:0045591, GO:0042036, GO:0001816, GO:0021549, GO:0032088, GO:0035067, GO:0045066, GO:0045085, GO:0045077, GO:0033092, GO:0051525, GO:0002725, GO:0031064 |
| InterPro ID |
IPR001766 |
| InterPro Term |
TF_fork_head |
| EMBL-Bank ID |
AJ005891, BC143785, BC143786, AF277993, DQ010327, BC113403, BC113401, AF235097, EF534714, EU855812 |
| Ensembl Protein ID |
ENSP00000365380, ENSP00000365369, ENSP00000365372, ENSP00000396415, ENSP00000428952, ENSP00000451208 |
| RefSeq ID |
NM_014009, NM_001114377, NP_054728, NP_001107849 |
| UniProt Accession |
B7ZLG1, Q9BZS1, B9UN80 |
| Description |
forkhead box P3 [Source:HGNC Symbol;Acc:6106] |
| Gene-Disease Assocation |
IMMUNODYSREGULATION, POLYENDOCRINOPATHY, AND ENTEROPATHY, X-LINKED;, DIABETES MELLITUS, INSULIN-DEPENDENT; IDDM |
| UniGene ID |
Hs.247700 |
| Entrez Gene ID |
50943 |
| Ensembl Gene ID |
ENSG00000049768 |
| HGNC Symbol |
FOXP3 |
| Ensembl Family |
ENSFM00620000999461 |
| Ensembl Family Description |
FORKHEAD BOX P3 |
| Ensembl Transcript ID |
ENST00000518685, ENST00000376207, ENST00000376197, ENST00000376199, ENST00000557224, ENST00000455775 |
| Design Element |
221333_at, g7661845_3p_x_at, 221334_s_at, g12407640_3p_at, ENST00000557224, ENST00000518685, ENST00000376207, ENST00000376199, g7661845_3p_a_at, ENST00000455775, ENST00000376197, 224211_at |
| Search EB-eye |
ENSG00000049768
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