KITLG
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Homo sapiens |
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KITLG is differentially expressed in 271 experiments: 105 organism parts: lung, bone marrow, ... (103 more);, 185 disease states: normal, cervical carcinoma, ... (183 more);, 90 cell types 380 cell lines 30 compound treatments and 76 other conditions. |
| Synonyms |
SCF, Kitl, MGF, SF, KL-1, FPH2 |
| Orthologs |
SCF_CHICK
(Gallus gallus)
Kitl
(Mus musculus)
SCF_BOVIN
(Bos taurus)
Kitlg
(Rattus norvegicus)
kitlg
(Xenopus laevis)
SCF_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
plasma membrane, protein binding, cytoskeleton, cytoplasm, cell proliferation, extracellular space, positive regulation of cell proliferation, membrane, negative regulation of apoptosis, growth factor activity, male gonad development, extracellular region, positive regulation of MAP kinase activity, cytokine activity, cell adhesion, hemopoiesis, germ cell programmed cell death, positive regulation of DNA replication, integral to membrane, signal transduction, positive regulation of Ras protein signal transduction, positive regulation of myeloid leukocyte differentiation, positive regulation of peptidyl-tyrosine phosphorylation, stem cell factor receptor binding, positive regulation of mast cell proliferation, ovarian follicle development, neural crest cell migration, negative regulation of mast cell apoptosis, positive regulation of melanocyte differentiation |
| Gene Ontology ID |
GO:0008283, GO:0008284, GO:0016020, GO:0016021, GO:0008083, GO:0007155, GO:0007165, GO:0008584, GO:0005615, GO:0005515, GO:0005576, GO:0005737, GO:0005886, GO:0005856, GO:0005125, GO:0043066, GO:0045740, GO:0046579, GO:0043406, GO:0030097, GO:0035234, GO:0002763, GO:0005173, GO:0050731, GO:0001755, GO:0070668, GO:0045636, GO:0001541, GO:0033026 |
| InterPro Term |
SCF |
| Ensembl Family |
ENSFM00250000003223 |
| InterPro ID |
IPR003452 |
| EMBL-Bank ID |
S42571, AF400437, AF400436, BC074725, AK293002, M59964, BC143899, CR749222, AF119835, AK290319, CH471054, BC069783, BC069797, BC069733, BC126166, S45983 |
| Description |
KIT ligand [Source:HGNC Symbol;Acc:6343] |
| Ensembl Protein ID |
ENSP00000367796, ENSP00000054216, ENSP00000228280, ENSP00000438889 |
| UniProt Accession |
P21583, Q16493 |
| Ensembl Gene ID |
ENSG00000049130 |
| RefSeq ID |
NM_003994, NP_003985, NM_000899, NP_000890 |
| Entrez Gene ID |
4254 |
| HGNC Symbol |
KITLG |
| UniGene ID |
Hs.1048 |
| Ensembl Family Description |
KIT LIGAND PRECURSOR MAST CELL GROWTH FACTOR MGF STEM CELL FACTOR SCF C KIT LIGAND [CONTAINS SOLUBLE KIT LIGAND SKITLG |
| Ensembl Transcript ID |
ENST00000552044, ENST00000347404, ENST00000378535, ENST00000537835, ENST00000228280, ENST00000357116 |
| Gene-Disease Assocation |
SKIN/HAIR/EYE PIGMENTATION, VARIATION IN, 7; SHEP7, HYPERPIGMENTATION, FAMILIAL PROGRESSIVE, 2; FPH2 |
| Design Element |
211124_s_at, 62480_at, 226534_at, ENST00000228280, ENST00000378535, 83799_at, M59964_at, ENST00000347404, Hs.5921.0.A1_3p_at, 207029_at, g4505174_3p_at, ENST00000537835, g4530470_3p_a_at, 597_at, ENST00000552044, ENST00000357116 |
| Search EB-eye |
ENSG00000049130
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