GAB2
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Homo sapiens |
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GAB2 is differentially expressed in 296 experiments: 107 organism parts: bone marrow, cerebellum, ... (105 more);, 168 disease states: normal, acute promyelocytic leukemia, ... (166 more);, 88 cell types 387 cell lines 33 compound treatments and 71 other conditions. |
| Synonyms |
KIAA0571 |
| Orthologs |
GAB2
(Danio rerio)
ENSGALG00000017264
(Gallus gallus)
ENSBTAG00000002922
(Bos taurus)
dos
(Drosophila melanogaster)
gab2
(Xenopus laevis)
ENSCAFG00000004782
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0048015, GO:0008284, GO:0007169, GO:0005515, GO:0005737, GO:0005886, GO:0005829, GO:0005070, GO:0005547, GO:0005068, GO:0043325, GO:0043306, GO:0030316 |
| Gene Ontology Term |
cytosol, plasma membrane, protein binding, cytoplasm, positive regulation of cell proliferation, transmembrane receptor protein tyrosine kinase signaling pathway, SH3/SH2 adaptor activity, phosphatidylinositol-3,4,5-trisphosphate binding, positive regulation of mast cell degranulation, phosphatidylinositol-3,4-bisphosphate binding, osteoclast differentiation, phosphatidylinositol-mediated signaling, transmembrane receptor protein tyrosine kinase adaptor activity |
| InterPro ID |
IPR001849 |
| InterPro Term |
Pleckstrin_homology |
| Ensembl Family |
ENSFM00580000902186 |
| Ensembl Family Description |
GRB2 ASSOCIATED BINDING GRB2 ASSOCIATED BINDER GROWTH FACTOR RECEPTOR BOUND 2 ASSOCIATED |
| UniProt Accession |
Q9UQC2, E9PJ26, E9PJE2 |
| Entrez Gene ID |
9846 |
| RefSeq ID |
NM_080491, NM_012296, NP_536739, NP_036428 |
| Ensembl Gene ID |
ENSG00000033327 |
| EMBL-Bank ID |
AB011143, AP003086, BC152459, CH471076, AP002985, BC131711, AB018413 |
| UniGene ID |
Hs.695032, Hs.429434 |
| Description |
GRB2-associated binding protein 2 [Source:HGNC Symbol;Acc:14458] |
| Ensembl Protein ID |
ENSP00000343959, ENSP00000354952, ENSP00000431868, ENSP00000433762 |
| HGNC Symbol |
GAB2 |
| Ensembl Transcript ID |
ENST00000530915, ENST00000528886, ENST00000526030, ENST00000340149, ENST00000528329, ENST00000534823, ENST00000361507 |
| Design Element |
ENST00000534823, ENST00000528886, 35253_at, 203853_s_at, ENST00000361507, ENST00000530915, ENST00000526030, ENST00000528329, ENST00000340149, g6912459_3p_a_at |
| Search EB-eye |
ENSG00000033327
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