FAS
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Homo sapiens |
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FAS is differentially expressed in 375 experiments: 166 organism parts: lung, kidney, ... (164 more);, 231 disease states: normal, prostate carcinoma, ... (229 more);, 112 cell types 531 cell lines 63 compound treatments and 76 other conditions. |
| Synonyms |
APT1, APO-1, FAS1, CD95, TNFRSF6 |
| Orthologs |
TNR6_BOVIN
(Bos taurus)
ENSMUSG00000024778
(Mus musculus)
fas
(Danio rerio)
FAS
(Gallus gallus)
Fas
(Rattus norvegicus)
NP_001096199.1
(Xenopus laevis)
FAS
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0009897, GO:0009986, GO:0016020, GO:0016021, GO:0007165, GO:0009636, GO:0007283, GO:0051402, GO:0051260, GO:0007568, GO:0042493, GO:0048471, GO:0005488, GO:0042802, GO:0005625, GO:0005515, GO:0005576, GO:0004871, GO:0004872, GO:0004888, GO:0006916, GO:0006915, GO:0006919, GO:0006917, GO:0006955, GO:0005886, GO:0005829, GO:0042981, GO:0032496, GO:0005031, GO:0043065, GO:0043066, GO:0019900, GO:0006461, GO:0042127, GO:0001666, GO:0045121, GO:0034097, GO:0010467, GO:0008625, GO:0008624, GO:0008633, GO:0010035, GO:0051384, GO:0048536, GO:0003014, GO:0042698, GO:0002377, GO:0006924, GO:0006927, GO:0006925, GO:0043627, GO:0031264, GO:0019724, GO:0031104, GO:0050869, GO:0043029, GO:0045619, GO:0045637, GO:0070848, GO:0043434, GO:0071285, GO:0071260, GO:0033209, GO:0045060, GO:0010940, GO:0031265, GO:0032464 |
| Gene Ontology Term |
cytosol, plasma membrane, protein binding, apoptosis, regulation of cell proliferation, response to toxin, membrane, protein homooligomerization, negative regulation of apoptosis, kinase binding, spermatogenesis, activation of caspase activity, extracellular region, membrane raft, protein complex assembly, anti-apoptosis, response to hypoxia, positive regulation of apoptosis, signal transducer activity, external side of plasma membrane, soluble fraction, identical protein binding, induction of apoptosis, response to lipopolysaccharide, tumor necrosis factor receptor activity, aging, receptor activity, immune response, response to drug, perinuclear region of cytoplasm, integral to membrane, binding, cell surface, signal transduction, neuron apoptosis, regulation of apoptosis, response to cytokine stimulus, tumor necrosis factor-mediated signaling pathway, activation of pro-apoptotic gene products, inflammatory cell apoptosis, regulation of myeloid cell differentiation, activation-induced cell death of T cells, cellular response to mechanical stimulus, negative thymic T cell selection, induction of apoptosis via death domain receptors, dendrite regeneration, B cell mediated immunity, death-inducing signaling complex, gene expression, immunoglobulin production, response to estrogen stimulus, spleen development, cellular response to lithium ion, positive regulation of necrotic cell death, response to growth factor stimulus, response to inorganic substance, regulation of lymphocyte differentiation, response to peptide hormone stimulus, T cell homeostasis, induction of apoptosis by extracellular signals, transformed cell apoptosis, negative regulation of B cell activation, renal system process, ovulation cycle, response to glucocorticoid stimulus, CD95 death-inducing signaling complex, positive regulation of protein homooligomerization, transmembrane signaling receptor activity |
| InterPro ID |
IPR001368, IPR000488, IPR008063 |
| InterPro Term |
TNFR_Cys_rich_reg, Death, Fas_rcpt |
| Ensembl Family |
ENSFM00500000270691 |
| EMBL-Bank ID |
AJ509181, M67454, AK290978, BC012479, FM246459, FM246458, AY450925, X63717, AL157394, X89101, CH471066, Z47994, Z47993, Z47995, AY495076, X83491, X83490, X83492, X83493, Z70519, Z70520 |
| Ensembl Protein ID |
ENSP00000425159, ENSP00000349896, ENSP00000347426, ENSP00000422453, ENSP00000424113, ENSP00000360942, ENSP00000423755, ENSP00000347979, ENSP00000420975, ENSP00000345601, ENSP00000441676 |
| UniGene ID |
Hs.244139, Hs.623093 |
| Description |
Fas (TNF receptor superfamily, member 6) [Source:HGNC Symbol;Acc:11920] |
| RefSeq ID |
NM_152871, NM_152872, NP_000034, NM_000043, NP_690611, NP_690610 |
| Ensembl Gene ID |
ENSG00000026103 |
| UniProt Accession |
B6VNV5, P25445, Q5T9P3, Q8IUB7, F5GWX3, F5H078 |
| HGNC Symbol |
FAS |
| Entrez Gene ID |
355 |
| Ensembl Family Description |
TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6 PRECURSOR APO 1 ANTIGEN APOPTOSIS MEDIATING SURFACE ANTIGEN FAS FASLG RECEPTOR CD95 ANTIGEN |
| Ensembl Transcript ID |
ENST00000355740, ENST00000460510, ENST00000540197, ENST00000492756, ENST00000313771, ENST00000352159, ENST00000494799, ENST00000477270, ENST00000488877, ENST00000494410, ENST00000484444, ENST00000466081, ENST00000357339, ENST00000371857, ENST00000371875, ENST00000487314, ENST00000355279, ENST00000479522 |
| Gene-Disease Assocation |
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME; ALPS |
| Design Element |
1808_s_at, ENST00000492756, Hs.82359.0.S1_3p_a_at, ENST00000484444, X63717_at, Hs.146747.0.S1_3p_at, Hs.82359.1.S1_3p_a_at, ENST00000488877, 389_s_at, 37644_s_at, X89101_s_at, ENST00000460510, ENST00000494799, ENST00000479522, ENST00000352159, ENST00000494410, ENST00000487314, X82279_s_at, 216252_x_at, ENST00000357339, ENST00000355279, ENST00000371875, 233820_at, ENST00000355740, ENST00000540197, ENST00000477270, 215719_x_at, X83492_at, 1441_s_at, 204780_s_at, 37643_at, ENST00000313771, g4507582_3p_a_at, ENST00000466081, X83492_s_at, ENST00000371857, 204781_s_at |
| Search EB-eye |
ENSG00000026103
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