SNAI2
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Homo sapiens |
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SNAI2 is differentially expressed in 239 experiments: 170 organism parts: uterus, adipose tissue, ... (168 more);, 205 disease states: normal, glioblastoma, ... (203 more);, 96 cell types 431 cell lines 35 compound treatments and 52 other conditions. |
| Synonyms |
SLUG, SLUGH1, SNAIL2 |
| Orthologs |
ENSGALG00000015241
(Gallus gallus)
snai2
(Danio rerio)
SNAI2_BOVIN
(Bos taurus)
ENSGALG00000022403
(Gallus gallus)
Snai2
(Mus musculus)
wor
(Drosophila melanogaster)
esg
(Drosophila melanogaster)
sna
(Drosophila melanogaster)
snai2
(Xenopus laevis)
A5HBK7_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cell migration, regulation of transcription, DNA-dependent, cytoplasm, nuclear chromatin, intracellular, negative regulation of apoptosis, metal ion binding, nucleic acid binding, sequence-specific DNA binding, multicellular organismal development, sensory perception of sound, positive regulation of histone acetylation, nucleus, canonical Wnt receptor signaling pathway, chromatin binding, negative regulation of transcription from RNA polymerase II promoter, epithelial to mesenchymal transition, response to radiation, zinc ion binding, negative regulation of cell adhesion mediated by integrin, positive regulation of survival gene product expression, neural crest cell development, positive regulation of cell migration, osteoblast differentiation, cartilage morphogenesis, pigmentation, negative regulation of cell adhesion involved in substrate-bound cell migration, regulation of osteoblast differentiation, negative regulation of chondrocyte differentiation, epithelium development, palate development, negative regulation of canonical Wnt receptor signaling pathway, positive regulation of fat cell differentiation, negative regulation of DNA damage response, signal transduction by p53 class mediator, white fat cell differentiation, negative regulation of vitamin D biosynthetic process, negative regulation of keratinocyte proliferation, desmosome disassembly, epithelial to mesenchymal transition involved in endocardial cushion formation, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, cellular response to epidermal growth factor stimulus, regulation of chemokine production, negative regulation of vitamin D receptor signaling pathway, negative regulation of catenin import into nucleus, cellular response to ionizing radiation, negative regulation of stem cell proliferation, sequence-specific distal enhancer binding RNA polymerase II transcription factor activity |
| Gene Ontology ID |
GO:0003682, GO:0003676, GO:0008270, GO:0003705, GO:0060070, GO:0016477, GO:0007275, GO:0007605, GO:0005622, GO:0005737, GO:0005634, GO:0043066, GO:0000790, GO:0000122, GO:0046872, GO:0006355, GO:0001837, GO:0043565, GO:0009314, GO:0035066, GO:0060429, GO:0060536, GO:0060021, GO:0014032, GO:0006933, GO:0090090, GO:0050872, GO:0045600, GO:0045667, GO:0043518, GO:0045885, GO:0001649, GO:0043473, GO:0033629, GO:0035414, GO:0030335, GO:0032331, GO:0010839, GO:0010957, GO:0032642, GO:0035921, GO:0070563, GO:0071479, GO:0071364, GO:0003198, GO:0001078, GO:2000647 |
| InterPro Term |
Znf_C2H2-like, Znf_C2H2 |
| InterPro ID |
IPR007087, IPR015880 |
| Ensembl Family |
ENSFM00500000269921 |
| Ensembl Family Description |
ZINC FINGER SNAI2 SLUG SNAIL HOMOLOG 2 |
| Ensembl Gene ID |
ENSG00000019549 |
| RefSeq ID |
NM_003068, NP_003059 |
| EMBL-Bank ID |
BC014890, AF084243, CH471068, AC013701, BC015895, AK312661, AF042001 |
| HGNC Symbol |
SNAI2 |
| Entrez Gene ID |
6591 |
| UniProt Accession |
O43623, C9JS24 |
| Description |
snail homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:11094] |
| UniGene ID |
Hs.360174 |
| Ensembl Protein ID |
ENSP00000020945, ENSP00000380034 |
| Gene-Disease Assocation |
PIEBALD TRAIT; PBT, WAARDENBURG SYNDROME, TYPE 2D; WS2D |
| Ensembl Transcript ID |
ENST00000020945, ENST00000396822 |
| Design Element |
213139_at, ENST00000396822, ENST00000020945, 38288_at, Hs.93005.0.S2_3p_at, 63992_at |
| Search EB-eye |
ENSG00000019549
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