ALOX5
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Homo sapiens |
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ALOX5 is differentially expressed in 304 experiments: 117 organism parts: bone marrow, cerebellum, ... (115 more);, 260 disease states: normal, control, ... (258 more);, 135 cell types 416 cell lines 32 compound treatments and 76 other conditions. |
| Synonyms |
5-LOX |
| Orthologs |
F1MQ78_BOVIN
(Bos taurus)
F6PID9_CIOIN
(Ciona intestinalis)
F6UJG6_CIOIN
(Ciona intestinalis)
ALOX5 (2 of 4)
(Danio rerio)
ALOX5
(Gallus gallus)
ALOX5 (4 of 4)
(Danio rerio)
ALOX5 (3 of 4)
(Danio rerio)
ALOX5 (1 of 4)
(Danio rerio)
Alox5
(Mus musculus)
ENSCING00000012298
(Ciona intestinalis)
F6Z015_CIOIN
(Ciona intestinalis)
Alox5
(Rattus norvegicus)
alox5
(Xenopus laevis)
ALOX5
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, oxidoreductase activity, leukotriene biosynthetic process, protein binding, iron ion binding, cytoplasm, membrane, metal ion binding, nuclear matrix, sensory perception of pain, sarcolemma, nuclear envelope lumen, soluble fraction, response to nutrient, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, nucleus, dendrite, nuclear envelope, nuclear membrane, lipoxygenase activity, arachidonate 5-lipoxygenase activity, leukotriene metabolic process, inflammatory response, acute inflammatory response, lipoxygenase pathway, leukotriene production involved in inflammatory response, response to hyperoxia, arachidonic acid metabolic process, positive regulation of vasoconstriction, oxidation-reduction process, prostanoid metabolic process |
| Gene Ontology ID |
GO:0016020, GO:0016491, GO:0016363, GO:0031965, GO:0007584, GO:0042383, GO:0016702, GO:0030425, GO:0005625, GO:0005506, GO:0005515, GO:0005737, GO:0005635, GO:0005634, GO:0005641, GO:0005829, GO:0055114, GO:0019370, GO:0046872, GO:0019233, GO:0016165, GO:0004051, GO:0002540, GO:0002526, GO:0006954, GO:0055093, GO:0006691, GO:0019372, GO:0019369, GO:0045907, GO:0006692 |
| InterPro ID |
IPR001024, IPR001885, IPR013819 |
| InterPro Term |
LipOase_LH2, LipOase_C, LipOase_mml |
| Ensembl Family Description |
ARACHIDONATE LIPOXYGENASE |
| Ensembl Family |
ENSFM00250000000705 |
| Description |
arachidonate 5-lipoxygenase [Source:HGNC Symbol;Acc:435] |
| EMBL-Bank ID |
J03571, J03600, BC130332, BC132677, BC143985, AL731567, J04520, M38191, HM592260, HM592259 |
| HGNC Symbol |
ALOX5 |
| UniProt Accession |
B7ZLS0, P09917, E5FPY7 |
| UniGene ID |
Hs.89499 |
| Ensembl Gene ID |
ENSG00000012779 |
| RefSeq ID |
NM_000698, NP_000689 |
| Ensembl Protein ID |
ENSP00000363512, ENSP00000437634 |
| Entrez Gene ID |
240 |
| Gene-Disease Assocation |
ASTHMA, SUSCEPTIBILITY TO |
| Ensembl Transcript ID |
ENST00000493336, ENST00000542434, ENST00000481117, ENST00000475300, ENST00000483623, ENST00000374391, ENST00000498461 |
| Design Element |
ENST00000483623, ENST00000498461, g4502056_3p_a_at, Hs.89499.2.S1_3p_a_at, ENST00000374391, ENST00000542434, Hs.89499.0.A1_3p_a_at, 214366_s_at, 204446_s_at, 204445_s_at, ENST00000481117, J03600_at, 307_at, ENST00000493336, ENST00000475300 |
| Search EB-eye |
ENSG00000012779
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