CASP10
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Homo sapiens |
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CASP10 is differentially expressed in 300 experiments: 155 organism parts: bone marrow, liver, ... (153 more);, 244 disease states: normal, chronic myelogenous leukemia, ... (242 more);, 95 cell types 393 cell lines 44 compound treatments and 74 other conditions. |
| Synonyms |
MCH4 |
| Orthologs |
Dcp-1
(Drosophila melanogaster)
decay
(Drosophila melanogaster)
casp8
(Danio rerio)
casp8l1
(Danio rerio)
Ice
(Drosophila melanogaster)
F7BL88_CIOIN
(Ciona intestinalis)
F1P102_CHICK
(Gallus gallus)
casp10
(Xenopus laevis)
CASP10
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008234, GO:0008233, GO:0004197, GO:0005515, GO:0006915, GO:0006917, GO:0005886, GO:0005829, GO:0042981, GO:0006508, GO:0045087, GO:0008624, GO:0043123 |
| Gene Ontology Term |
cytosol, plasma membrane, protein binding, apoptosis, innate immune response, peptidase activity, induction of apoptosis, cysteine-type endopeptidase activity, proteolysis, cysteine-type peptidase activity, regulation of apoptosis, positive regulation of I-kappaB kinase/NF-kappaB cascade, induction of apoptosis by extracellular signals |
| InterPro Term |
Pept_C14_p10, Pept_C14_ICE_p20, Pept_C14_p45_core, Pept_C14_cat, DED |
| InterPro ID |
IPR001309, IPR011600, IPR015917, IPR002138, IPR001875 |
| Ensembl Family |
ENSFM00500000269928 |
| Ensembl Family Description |
CASPASE PRECURSOR CASP APOPTOTIC PROTEASE MCH ICE APOPTOTIC PROTEASE [CONTAINS CASPASE SUBUNIT CASPASE SUBUNIT |
| Description |
caspase 10, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1500] |
| EMBL-Bank ID |
AC007283, EF050529, AY690601, BC042844, AJ487679, AJ487678, U60519, AF111345, AF111344, CH471063, AK304859, U86214, AB038979 |
| UniProt Accession |
Q92851, Q68HC0, B4E3T5 |
| Ensembl Protein ID |
ENSP00000401914, ENSP00000237865, ENSP00000286186, ENSP00000272879, ENSP00000396835, ENSP00000353250, ENSP00000314599, ENSP00000363781 |
| Gene-Disease Assocation |
LYMPHOMA, NON-HODGKIN, FAMILIAL, GASTRIC CANCER, GASTRIC CANCER, HEREDITARY DIFFUSE; HDGC, AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE IIA; ALPS2A |
| RefSeq ID |
NP_001221, NM_001230, NM_032974, NM_032977, NP_116756, NP_116759, NP_001193471, NP_001193453, NM_032976, NM_001206542, NM_001206524, NP_116758 |
| UniGene ID |
Hs.605938, Hs.5353 |
| Entrez Gene ID |
843 |
| Ensembl Gene ID |
ENSG00000003400 |
| HGNC Symbol |
CASP10 |
| Ensembl Transcript ID |
ENST00000438843, ENST00000286186, ENST00000360132, ENST00000485408, ENST00000471191, ENST00000313728, ENST00000460140, ENST00000492363, ENST00000374650, ENST00000346817, ENST00000484926, ENST00000448480, ENST00000272879 |
| Design Element |
211888_x_at, U60519_at, 205467_at, ENST00000492363, ENST00000484926, 210955_at, ENST00000313728, 83803_at, ENST00000360132, ENST00000272879, ENST00000286186, U86214_at, ENST00000485408, 1765_at, g4502568_3p_at, 39999_at, g1835778_3p_at, 210708_x_at, ENST00000471191, ENST00000448480, g4731236_3p_s_at, ENST00000460140, 1766_g_at, 1326_at, ENST00000374650, ENST00000346817, ENST00000438843 |
| Search EB-eye |
ENSG00000003400
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