Transcription profiling of mouse models with liver-specific deletion or global hypomorphic expression of the NADPH-cytochrome P450 reductase gene to study molecular mechanisms for the regulation of microsomal cytochrome P450 and the fatty liver phenotype.
Microarray 1-colour mRNA
Organism:
Mus musculus
Array Design(s):
Affymetrix GeneChip Mouse Genome 430A 2.0 [Mouse430A_2]
Publication:
- Weng Y, DiRusso CC, Reilly AA, Black PN, Ding X. et al. (2005) Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype.