Cs
SKYVDRVIAEVEKKYADEPEFVQTVEEVLSSL--GPVVDAHPEYEEVALLERMVIPERVI
EFRVPWEDDNGKVHVNTGYRVQFNGAIGPYKGGLRFAPSVNLSIMKFLGFEQAFKDSLTT
LPMGGAKGGSDFDPNGKSDREVMRFCQAFMTELYRHIGPDIDVPAGDLGVGAREIGYMYG
QYRKIVGGFYNGVLTGKARSFGGSLVRPEATGYGSVYYVEAVMKHENDT---LVGKTVAL
AGFGNVAWGAAKKLAELGAKAVTLSGPDGYIYD--PEGITTEEKINYMLEMRASGRN-KV
QDYADKFG------VQFFPGEKPWG---QKVDIIMPCATQNDVDLEQAKKIVANNVKYYI
EVANMPTTNEALR-FLMQQ------??MVVAPSKAVNAGGVLVSGFEMSQNSERLSWTAE
EVDSKLHQVMTDIHDGSAAAAERYGLGY------?LVAGANIVGFQKIADAMMAQGIAW

Ec
??????????VQKRDPNQTEFAQAVREVMTTL--WPFLEQNPKYRQMSLLERLVEPERVI
QFRVVWVDDRNQIQVNRAWRVQFSSAIGPYKGGMRFHPSVNLSILKFLGFEQTFKNALTT
LPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGADTDVPAGDIGVGGREVGFMAG
MMKKLSNNTA-CVFTGKGLSFGGSLIRPEATGYGLVYFTEAMLKRHGMG---FEGMRVSV
SGSGNVAQYAIEKAMEFGARVITASDSSGTVVD--ESG-FTKEKLARLIEIKASRDG-RV
ADYAKEFG------LVYLEGQQPWS---LPVDIALPCATQNELDVDAAHQLIANGVKAVA
EGANMPTTIEATELF--QQ------AGVLFAPGKAANAGGVATSGLEMAQNAARLGWKAE
KVDARLHHIMLDIHHAC??????????-------??VQGANIAGFVKVADAMLAQG??-

St
??????????VQKRDPHQTEFAQAVREVMTTL--WPFLEQNPRYRHMSLLERLVEPERVI
QFRVVWLDDKNQVQVNRAWRVQFNSAIGPYKGGMRFHPSVNLSILKFLGFEQTFKNALTT
LPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGPDTDVPAGDIGVGGREVGFMAG
MMRKLSNNSS-CVFTGKGLSFGGSLIRPEATGYGLVYFTEAMLKRHGLG---FEGMRVAV
SGSGNVAQYAIEKAMAFGARVVTASDSSGTVVD--ESG-FTPEKLARLCEIKASRDG-RV
ADYARDFG------LTYLEGQQPWS---VPVDIALPCATQNELDVDAARVLIANGVKAVA
EGANMPTTIEATDLFL?--------AGVLFAPGKAANAGGVATSGLEMAQNAARLSWKAE
KVDARLHHIMLDIHHAC??????????-------??VQGANIAGFVKVADAMLAQG??-

Cg
??????????LLKRNAGEPEFHQAVAEVLESL--KLVLEKDPHYADYGLIQRLCEPERPV
IFRVPWVDDQGQVHVNRGFRVQFNSALGPYKGGLRNHPSVNLGIVKFLGFGEIFKNSLTG
LPIGGGKGGSDFDPKGKSDLEIMRFCKSFMTELHRHIGEYRDVPAGDIGVGGREIGYLFG
HYRRMANQHESGVLTGKGLTWGGSLVRTEATGYGCVYFVSEMIKAKGES---ISGQKIIV
SGSGNVATYAIEKAQELGATVIGFSDSSGWVHT--PNG-VDVAKLREIKEVRRARVS-VY
AD??????-------???????-WD---LKCDIALPCATQNELNGENAKTLADNGCRFVA
EGANMPSTPEAVEVF??--------??IRFGPGKAANVGGVATSALEMQQNASR?????-
????????????????????????????-?????-LV-GANIAGFKKVADAMLAQG??-

unknown
??????????LQRHNPHQPEYLQAVREVFTSL--WPFIERNPAYREQALLERLVEPERII
QFRVSWVDDRGQVQVNRAFRVQFNSAIGPYKGGMRFHPSVNLSILKFLGFEQTFKNALTT
LPMGGGKGGSDFDPKGKSQGRIMRFCQALMTELYRHLGPDTDVPAGDIGDGGREVGFMAG
MMKKLSNNTA-CVFTGKGLSFGGSLIRPEATGYGLVYFTDAMLQRHGLG---FEGMRVAV
SGSGNVAQYTIEKALELDARVITVSDSGGTLVD--EDG-FTTEKLAHLAEIKNQRYG-RV
ADYAAERG------LTYLAGQQPWN---VPVDIALPCATQNELDLEAARVIR-NGVKAVA
EGANMPTTIQATDAFL?--------AGVLFAPGKAANAAGLATSGLEMAQNAARIGWRAE
KVDVRLQHIMADIHHAC??????????-------??VHGANIAGFVKVAEAMLAQG??-

Gl
???????IAVIKQRDGHMTEFRQAVEEVVDSL--KVIFEREPKYI--PIFERMLEPERVI
IFRVPWMDDAGRINVNRGFRVQYNSALGPYKGGLRFHPSVNLSILKFLGFEQILKNSLTT
LPMGGGKGGSDFDPKGKSDNEVMRFCQSFMTELQRHVGADTDVPAGDIGVGAREIGYLYG
QYKRLRNEFT-GVLTGKNVKWGGSFIRPEATGYGAVYFLEEMCKDNNTV---IRGKNVLL
SGSGNVAQFACEKLIQLGAKVLTFSDSNGTIVD--KDG-FNEEKLAHLMYLKNEKRG-RV
SEFKDK???-----VAYYEGKKPW???????DCIMPCATQNEVSGDDATRLVGLGLKFVA
EGANMPSTAEAVHVY??--------?GVMYGPAKASNAGGVSVSGLEMSQNSVRLQWTAE
EVDQKLRGIMRGIFVACRDTAKKY????------??QMGANIAGFLKVADSMIEQG??-

Ch
???????LTEIFMKDPEQQEFMQAVREVAVSL--QPVFEKRPELL--PIFKQIVEPERVI
TFRVSWLDDAGNLQVNRGFRVQYSSAIGPYKGGLRFHPSVNLSIMKFLAFEQIFKNSLTT
LPMGGGKGGSDFDPKGKSDAEVMRFCQSFMTELQRHISYVQDVPAGDIGVGAREIGYLFG
QYKRITKNYT-GVLTGKGQEYGGSEIRPEATGYGAVLFVENVLKDKGES---LKGKRCLV
SGAGNVAQYCAELLLEKGAIVLSLSDSQGYVYE--PNG-FTREQLQAVQDMKKKNNSARI
SEYK????------???????KPWE-????VDIAFPCATQNEIDEHDAELLIKHGCQYVV
EGANMPSTNEAIHKY??--------AGIIYCPGKAANAGGVAVSGLEMTQNRMSLNWTRE
EVRDKLERIMKDIYDSAMGPSREY??--------?LAAGANIAGFTKVADAVKAQG??-

Nc
------------???PSEPEFEQAYKELAYTLENSSLFQKHPEYR--TALTVASIPERVI
QFRVVWEDDNGNVQVNRGYRVQFNSALGPYKGGLRLHPSVNLSILKFLGFEQIFKNALTG
LSMGGGKGGADFDPKGKSDAEIRRFCCAFMAELHKHIGADTDVPAGDIGVGGREIGYMFG
AYRKAANRFE-GVLTGKGLSWGGSLIRPEATGYGLVYYVGHMLEYSGAG--SYAGKRVAL
SGSGNVAQYAALKLIELGATVVSLSDSKGALVATGESG-ITVEDINAVMAIKEARQS-??
???????-------LKWIEGARPW??-VGKVDIALPCATQNEVSKEEAEGLLAAGCKFVA
EGSNMGCTLEAIEVF????KEKKG-?AVWYAPGKAANCGGVAVSGLEMAQNSQRLNWTQA
EVDEKLKDIMKNAFFNGLNTAKTY???-AEGELPSLVAGSNIAGFVKVAQAMHDQGDWW

An
-----------????PVEPEFEQAYKELASTLENSTLFEQHPEYR--RALQVVSVPERVI
QFRVVWENDKGEVQINRGYRVQFNSALGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTG
LNMGGGKGGSDFDPKGKSDSEIRRFCTAFMTELCKHIGADTDVPAGDIGVTGREVGFLFG
QYRRIRNQWE-GVLTGKGGSWGGSLIRPEATGYGVVYYVQHMIKHVTGGKESFAGKRVAI
SGSGNVAQYAALKVIELGGSVVSLSDSKGSLIVKDESASFTPEEIALIADLKVARKQ-?-
????????FAG--???YIPDARPWTNI?GKFEVALPSATQNEVSGEEAEHLIKSGVRYIA
EGSNMGCTQAAIDIF????NANPG-?AIWYAPGKAANAGGVAVSGLEMAQNSARLSWTSE
EVDARLKGIMEDCFKNGLETAQKF???-AKGVLPSLVTGSNIAGFTKVAEAMKDQGDWW

Sc
---------------?SEPEFQQAYEEVVSSLEDSTLFEQHPEYR--KVLPIVSVPERII
QFRVTWENDKGEQEVAQGYRVQYNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNSLTG
LDMGGGKGGLCVDLKGRSNNEIRRICYAFMRELSRHIGQDTDVPAGDIGVGGREIGYLFG
AYRSYKNSWE-GVLTGKGLDWGGSLIRPEATGYGLVYYTQAMIDYATNGKESFEGKRVTI
SGSGNVAQYAALKVIELGGTVVSLSDSKGCIIS--ETG-ITSEQVADISSAKVNFKS-??
????????FS-ENKVQYIAGARPWTH-VQKVDIALPCATQNEVSGEEAKALVAQGVKFIA
EGSNMGSTPEAIAVF?????????QATVWYGPPKAANLGGVAVSGLEMAQNSQRITWTSE
RVDQELKRIMINCFNECIDYAKKY???-????LPSLVKGANIASFIKVSDAMFDQGD??

So
---------??????PHEPEFQQAYNELVSALEESTLFTEKPEYK--KVIPVVSIPERII
QFRVAWENDNGDVEVNNGFRVQFNSSLGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTG
LSMGGGKGGCDFNPKGRSDGEIRRFCVAFMRQLARYIGADTDVPAGDIGVGGREIGYLFG
AYKQMQNNWY-GVLTGKGLTWGGSLIRPEATGYVSFTTLKKMIEKATNGKESFKGKRVEL
SGSGNVAQYAALKVIELGGIVVSLSDSKGSIVS--KNG-IVPEQVLEIAAAKLKFKS???
????????FSGENSVEYLAGVRPWAK-VGHFDVALPSATQKEVSGEEAKALVEAGCKYIA
EGSNMGSTKEAIDVF?????-----??VWYAPGKAANCGGVAVSGLEMAQNSQRVQWSAE
EVDAKLKNIMYTCFDNCYDPAIKY????????LPSLLKGANIASFIKVADAMFDQGD??