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PANDIT
Protein and Associated NucleotideDomains with Inferred Trees
(View summary and phylogenies for PF01365 - RYDR_ITPR)
FAM  PF01365
PID  RYDR_ITPR
DES  RIH domain
IPR  IPR000699
ANO  18
ALN  250
AID  0.280956
APH  (((((((ITPR2_HUMAN/471-677:0.13998,ITPR3_HUMAN/471-677:0.15654):0.11768,ITPR1_MOUSE/472-677:0.13331):0.00000,(IP3R_DROME/492-704:0.14982,O77089_PANAR/461-675:0.23786):0.16333):0.72485,((Q29621_RABIT/451-655:0.10787,(RYR1_PIG/440-644:0.15657,RYR3_HUMAN/438-642:0.15615):0.04983):0.19201,(RY44_DROME/439-648:0.16935,P91905_CAEEL/447-653:0.33746):0.12743):1.25075):0.28042,((IP3R_DROME/1275-1456:0.19451,O77089_PANAR/1214-1394:0.22210):0.04671,((ITPR3_HUMAN/1171-1345:0.29436,ITPR2_HUMAN/1181-1355:0.12089):0.06869,ITPR1_MOUSE/1175-1354:0.08030):0.16085):1.00398):2.18484,RYR1_PIG/2158-2366:0.15631):0.29077,RY44_DROME/2224-2453:0.18136,P91905_CAEEL/2240-2464:0.18685);
ATP  (((((((ITPR2_HUMAN/471-677,ITPR3_HUMAN/471-677),ITPR1_MOUSE/472-677),(IP3R_DROME/492-704,O77089_PANAR/461-675)),((Q29621_RABIT/451-655,(RYR1_PIG/440-644,RYR3_HUMAN/438-642)),(RY44_DROME/439-648,P91905_CAEEL/447-653))),((IP3R_DROME/1275-1456,O77089_PANAR/1214-1394),((ITPR3_HUMAN/1171-1345,ITPR2_HUMAN/1181-1355),ITPR1_MOUSE/1175-1354))),RYR1_PIG/2158-2366),RY44_DROME/2224-2453,P91905_CAEEL/2240-2464);
ATL  10.0032
DNO  16
DLN  750
DID  0.415905
DPH  ((((((ITPR3_HUMAN/471-677:0.16147,ITPR2_HUMAN/471-677:0.28896):0.04081,ITPR1_MOUSE/472-677:0.19667):0.03389,(IP3R_DROME/492-704:0.16849,O77089_PANAR/461-675:0.33715):0.09838):0.41615,((RYR3_HUMAN/438-642:0.19129,Q29621_RABIT/451-655:0.19952):0.12477,(RY44_DROME/439-648:0.26532,P91905_CAEEL/447-653:0.36355):0.10258):0.50690):0.13612,((IP3R_DROME/1275-1456:0.19528,O77089_PANAR/1214-1394:0.30440):0.07862,((ITPR1_MOUSE/1175-1354:0.14160,ITPR2_HUMAN/1181-1355:0.22690):0.05464,ITPR3_HUMAN/1171-1345:0.22436):0.06591):0.49241):0.90207,RY44_DROME/2224-2453:0.07664,P91905_CAEEL/2240-2464:0.41575);
DTP  ((((((ITPR3_HUMAN/471-677,ITPR2_HUMAN/471-677),ITPR1_MOUSE/472-677),(IP3R_DROME/492-704,O77089_PANAR/461-675)),((RYR3_HUMAN/438-642,Q29621_RABIT/451-655),(RY44_DROME/439-648,P91905_CAEEL/447-653))),((IP3R_DROME/1275-1456,O77089_PANAR/1214-1394),((ITPR1_MOUSE/1175-1354,ITPR2_HUMAN/1181-1355),ITPR3_HUMAN/1171-1345))),RY44_DROME/2224-2453,P91905_CAEEL/2240-2464);
DTL  6.83063
RID  0.286486
RPH  (((IP3R_DROME/1275-1456:0.19543,O77089_PANAR/1214-1394:0.22283):0.04409,((RY44_DROME/2224-2453:0.26845,P91905_CAEEL/2240-2464:0.08448):2.43649,((((IP3R_DROME/492-704:0.15036,O77089_PANAR/461-675:0.23841):0.16591,ITPR1_MOUSE/472-677:0.13151):0.01778,(ITPR2_HUMAN/471-677:0.14029,ITPR3_HUMAN/471-677:0.15574):0.10293):0.69819,((RYR3_HUMAN/438-642:0.16737,Q29621_RABIT/451-655:0.13742):0.18112,(RY44_DROME/439-648:0.18730,P91905_CAEEL/447-653:0.32180):0.10984):1.28355):0.25258):1.03579):0.16355,ITPR1_MOUSE/1175-1354:0.08008,(ITPR2_HUMAN/1181-1355:0.12081,ITPR3_HUMAN/1171-1345:0.29619):0.06919);
RTP  (((IP3R_DROME/1275-1456,O77089_PANAR/1214-1394),((RY44_DROME/2224-2453,P91905_CAEEL/2240-2464),((((IP3R_DROME/492-704,O77089_PANAR/461-675),ITPR1_MOUSE/472-677),(ITPR2_HUMAN/471-677,ITPR3_HUMAN/471-677)),((RYR3_HUMAN/438-642,Q29621_RABIT/451-655),(RY44_DROME/439-648,P91905_CAEEL/447-653))))),ITPR1_MOUSE/1175-1354,(ITPR2_HUMAN/1181-1355,ITPR3_HUMAN/1171-1345));
RTL  9.45948
LNK  IP3R_DROME/1275-1456:P29993:AE003602
LNK  IP3R_DROME/492-704:P29993:D90403
LNK  ITPR1_MOUSE/1175-1354:P11881:X15373
LNK  ITPR1_MOUSE/472-677:P11881:X15373
LNK  ITPR2_HUMAN/1181-1355:Q14571:D26350
LNK  ITPR2_HUMAN/471-677:Q14571:D26350
LNK  ITPR3_HUMAN/1171-1345:Q14573:D26351
LNK  ITPR3_HUMAN/471-677:Q14573:D26351
LNK  O77089_PANAR/1214-1394:O77089:AF055079
LNK  O77089_PANAR/461-675:O77089:AF055079
LNK  P91905_CAEEL/2240-2464:P91905:D45899
LNK  P91905_CAEEL/447-653:P91905:D45899
LNK  Q29621_RABIT/451-655:Q29621:U50465
LNK  RY44_DROME/2224-2453:Q24498:AE003835
LNK  RY44_DROME/439-648:Q24498:D17389
LNK  RYR1_PIG/2158-2366:P16960:
LNK  RYR1_PIG/440-644:P16960:
LNK  RYR3_HUMAN/438-642:Q15413:AJ001515
AMK  xxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
DMK  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
NAM  P91905_CAEEL/447-653
ASQ  EVLKLMEDLIEYFAQPNDEQD---FE...EKQNHLRALRSRQDLFQEEGVLNMILDTIDKFSQMEALPDFAG.-----LIGEETHVKWE................QISTYLYLLVAAMIKGNHYNCAQFASAQR-LDWLFGRLSNPQSAEG--ILDVLYCVLTESPEALNMINEGH-IRSVISLLEKVG.-RDPKVLDVLSSLCEGNGMAVRSSQ--NLIT-QYLLPGK------DLLLQTSMRDHVSSM
DSQ  GAAGTTTTAAAATTGATGGAAGATCTCATTGAATACTTTGCACAACCAAATGATGAGCAAGAC---------TTTGAG.........GAGAAACAGAATCACTTGAGAGCTCTTCGTAGTCGGCAAGATCTTTTCCAAGAAGAAGGAGTTCTTAATATGATTCTTGACACTATCGACAAATTCTCTCAAATGGAGGCGCTTCCTGATTTCGCTGGA...---------------TTAATCGGAGAAGAGACTCATGTGAAATGGGAG................................................CAGATCTCTACTTATCTGTATCTTTTGGTAGCTGCTATGATTAAGGGAAATCATTATAATTGTGCCCAATTTGCCTCAGCTCAGAGA---CTGGATTGGTTGTTCGGAAGATTAAGCAACCCACAATCAGCCGAAGGA------ATTCTTGATGTACTGTATTGTGTGCTTACTGAATCTCCAGAAGCTTTGAATATGATTAACGAAGGGCAC---ATTCGATCTGTCATTTCTTTGTTAGAAAAAGTAGGA...---AGAGATCCAAAAGTGTTAGATGTGCTGTCGTCATTGTGCGAAGGAAACGGGATGGCTGTCAGAAGTTCACAA------AACCTGATCACT---CAGTACCTTCTGCCTGGGAAA------------------GATCTTCTCCTGCAAACATCAATGAGGGATCACGTATCCAGTATG
TRN  10010101100011000
NAM  RY44_DROME/439-648
ASQ  EMVMCLEDLINYFSQPEDDME---HE...EKQNRFRALRNRQDLFQEEGVLNLILEAIDKINIITSQGFLAS.----FLAGDETGQSWD................LISTYLYQLLAAIIKGNHTNCAQFANSNR-LNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEH-IKVIISLLEKHG.-RDPKVLDVLCSLCVGNGVAVRSSQ--NNIC-DFLLPGK------NLLLQTLLVDHVASI
DSQ  GAGATGGTCATGTGCCTTGAGGACTTGATTAACTACTTTTCGCAACCCGAAGACGATATGGAG---------CACGAG.........GAGAAACAGAACCGATTCCGTGCCCTGCGCAACCGACAGGATCTGTTCCAGGAGGAGGGCGTGCTCAATCTGATCCTGGAGGCCATTGACAAGATCAACATAATCACCTCGCAGGGCTTCCTAGCCAGC...------------TTCCTGGCCGGCGACGAGACCGGCCAGAGCTGGGAT................................................CTCATCTCCACCTATTTGTACCAACTCTTGGCCGCCATCATCAAGGGCAACCACACGAACTGCGCCCAGTTCGCGAACAGTAACCGA---CTCAACTGGCTATTCTCCCGCCTCGGTTCCCAGGCCTCCAGCGAGGGTTCCGGCATGTTGGACGTACTTCACTGCGTGCTGATCGATTCGCCAGAGGCACTAAACATGATGCGGGATGAGCAC---ATCAAGGTGATCATCTCCCTGCTGGAGAAGCACGGC...---AGGGACCCGAAAGTCCTAGACGTTCTGTGTTCCTTGTGCGTGGGTAATGGAGTGGCGGTGCGATCCTCCCAG------AACAACATTTGC---GACTTTTTGCTACCGGGCAAG------------------AATCTGTTGCTACAGACGCTCCTGGTGGACCATGTGGCCAGCATC
TRN  10010101100011011
NAM  Q29621_RABIT/451-655
ASQ  SVSLSLQDLIGYFHPPDEHLE---HE...DKQNRLRALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFAD.-----VAGREAGESWK................SILNSLYELLAALIRGNRKNCAQFSGSLD---WLISRLERLEASSG--ILEVLHCVLVESPEALNIIKEGH-IKSIISLLDKHG.-RNHKVLDVLCSLCVCHGVAVRSNQ--HLIC-DNLLPGR------DLLLQTRLVNHVSSM
DSQ  TCGGTGAGTCTGAGTCTGCAGGACCTGATCGGCTACTTCCACCCCCCGGATGAACACTTGGAG---------CATGAG.........GACAAGCAGAACAGACTGCGGGCCCTGAAGAACAGGCAGAACCTCTTCCAGGAAGAGGGAATGATCAACCTCGTGCTTGAGTGCATAGACCGACTGCATGTCTACAGCAGTGCAGCTCACTTTGCCGAT...---------------GTCGCCGGGAGAGAAGCGGGGGAATCTTGGAAA................................................TCCATTCTGAATTCTCTATATGAGTTGTTGGCGGCTCTAATTAGAGGAAATCGTAAAAACTGTGCTCAGTTTTCGGGCTCCCTTGAC---------TGGTTGATCAGCAGATTGGAGAGACTGGAAGCTTCCTCGGGT------ATTCTTGAAGTTTTACATTGTGTTTTAGTAGAAAGTCCAGAAGCTCTAAATATTATTAAAGAAGGACAT---ATTAAATCTATTATCTCACTTTTAGATAAGCATGGA...---AGAAATCACAAGGTCCTGGATGTCTTGTGCTCCCTGTGTGTTTGCCACGGGGTTGCAGTCCGTTCTAACCAG------CATCTCATTTGT---GACAACCTCCTGCCAGGAAGA------------------GATCTGTTATTGCAGACACGTCTTGTAAACCACGTTAGCAGCATG
TRN  10010101100011000
NAM  RYR1_PIG/440-644
ASQ  GVILSLQDLIGYFEPPSEELQ---HE...EKQSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAE.-----FAGEEAAESWK................EIVNLLYEILASLIRGNRANCALFSNNLD---WLVSKLDRLEASSG--ILEVLYCVLIESPEVLNIIQENH-IKSIISLLDKHG.-RNHKVLDVLCSLCVCNGVAVRSNQ--DLIT-ENLLPGR------ELLLQTNLINYVTSI
NAM  RYR3_HUMAN/438-642
ASQ  EVLQTLQDLIAYFQPPEEEMR---HE...DKQNKLRSLKNRQNLFKEEGMLALVLNCIDRLNIYNSVAHFAG.-----IAREESGMAWK................EILNLLYKLLAALIRGNRNNCAQFSNNLD---WLISKLDRLESSSG--ILEVLHCILTESPEALNLIAEGH-IKSIISLLDKHG.-RNHKVLDILCSLCLCNGVAVRANQ--NLIC-DNLLPRR------NLLLQTRLINDVTSI
DSQ  GAAGTCCTGCAGACCCTACAGGACTTGATCGCCTACTTCCAGCCCCCAGAGGAGGAGATGCGA---------CATGAA.........GACAAGCAGAACAAGCTCCGCTCACTCAAAAACAGACAAAATCTTTTCAAGGAAGAGGGAATGTTGGCCCTTGTCTTAAATTGCATTGACCGCTTAAATATCTACAATAGCGTAGCACACTTTGCAGGG...---------------ATTGCAAGGGAAGAGAGTGGCATGGCCTGGAAA................................................GAAATTCTGAACCTCCTCTACAAATTGCTGGCTGCTCTCATTCGCGGAAACAGAAACAATTGCGCTCAATTCTCCAATAACCTTGAT---------TGGCTCATCAGTAAATTGGACAGACTAGAATCTTCCTCAGGT------ATCTTGGAAGTTTTGCACTGCATCTTAACTGAAAGCCCAGAAGCCTTAAATCTGATAGCGGAGGGCCAC---ATCAAGTCGATCATCTCCCTGTTGGATAAGCACGGG...---CGGAATCACAAGGTTCTGGATATCCTGTGCTCCCTCTGTCTCTGCAATGGGGTTGCAGTGAGAGCCAACCAG------AATCTGATCTGT---GACAACTTGCTGCCCCGGAGA------------------AACCTACTCCTGCAGACACGACTGATTAACGATGTAACCAGTATC
TRN  10010101100011000
NAM  ITPR3_HUMAN/471-677
ASQ  FVIQLLEDLVFFVSDVPN---NGQNV...LDIMVTKPNRERQKLMREQNILKQVFGILKAPFREK---GGEGpLVRLEELSDQKNAPYQ................HMFRLCYRVLRHSQEDYRKNQEHIAKQFG--------MMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRK--.NREPRFLDYLSDLCVSNHIAIPVTQ--ELICKCVLDPKN-----SDILIRTELRPVKEMA
DSQ  TTTGTCATCCAGCTGCTGGAAGACCTGGTGTTCTTTGTCAGCGATGTCCCCAAC---------AATGGGCAGAATGTC.........CTGGACATCATGGTCACTAAGCCCAACCGGGAACGGCAGAAGCTGATGAGGGAGCAGAACATCCTCAAACAGGTCTTTGGCATTCTGAAGGCCCCGTTCCGTGAGAAG---------GGGGGTGAAGGTcccCTGGTGCGGCTGGAGGAGCTGTCAGACCAGAAGAACGCCCCCTACCAG................................................CACATGTTCCGCCTGTGCTACCGCGTGTTGCGGCATTCCCAGGAGGACTACCGCAAGAACCAGGAGCACATTGCCAAGCAGTTTGGG------------------------ATGATGCAGTCCCAGATTGGCTACGACATCCTGGCCGAGGACACCATCACTGCCCTGCTGCACAACAACCGCAAGCTCCTGGAAAAGCACATCACCAAGACCGAGGTGGAGACCTTCGTCAGCCTTGTGCGCAAG------...AACCGGGAGCCCAGGTTCCTGGACTACCTCTCTGACCTGTGTGTGTCCAACCACATCGCCATCCCCGTCACCCAA------GAGCTCATCTGCAAGTGTGTGCTGGACCCCAAGAAC---------------AGTGACATTCTCATCCGGACCGAGCTTCGGCCCGTGAAGGAGATGGCC
TRN  10010101100011001
NAM  ITPR2_HUMAN/471-677
ASQ  FVTKLLEDLIFFVADVPN---NGQEV...LDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSM-.-LRLEDLGDQRYAPYK................YMLRLCYRVLRHSQQDYRKNQEYIAKNFC--------VMQSQIGYDILAEDTITPLLHNNRKLLEKHITAKEIETFVSLLRR--.NREPRFLDYLSDLCVSNTTAIPVTQ--ELICKFMLSPGN-----ADILIQTKVVSMQADN
DSQ  TTTGTAACCAAATTATTGGAAGATCTCATATTCTTTGTTGCTGATGTGCCTAAT---------AATGGACAAGAAGTT.........CTGGATGTGGTTATCACTAAGCCAAACCGAGAGCGTCAAAAATTGATGAGGGAACAAAACATACTGGCACAGGTATTTGGAATTCTTAAAGCACCCTTTAAAGAGAAAGCAGGAGAAGGCTCGATG---...---CTGAGACTTGAAGATCTGGGGGATCAAAGATATGCACCCTACAAG................................................TACATGCTGCGGCTCTGTTACCGCGTCCTGAGACACTCGCAGCAGGATTACCGGAAAAATCAGGAATATATTGCTAAGAATTTCTGT------------------------GTCATGCAGTCCCAGATTGGCTATGATATTTTGGCAGAAGATACTATCACACCTTTGTTGCACAACAACAGAAAACTACTAGAGAAACATATCACAGCAAAAGAAATAGAAACATTTGTCAGTTTACTCAGGAGA------...AATCGGGAGCCAAGGTTTTTGGATTATTTGTCAGATCTGTGTGTGTCTAATACCACTGCTATCCCTGTAACTCAA------GAACTCATCTGTAAATTTATGTTGAGTCCAGGCAAT---------------GCAGACATTCTCATTCAAACTAAGGTGGTCTCAATGCAAGCAGACAAC
TRN  10010101100011000
NAM  ITPR1_MOUSE/472-677
ASQ  SVTKLLEDLVYFVTGGTNSGQ---DV...LEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDC--GDGPM.-LRLEELGDQRHAPFR................HICRLCYRVLRHSQQDYRKNQEYIAKQFG--------FMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRK--.NREPRFLDYLSDLCVSMNKSIPVTQ--ELICKAVLNPTN-----ADILIETKLVLSRFEF
DSQ  TCTGTCACGAAGCTTTTGGAAGACTTGGTTTACTTTGTCACGGGTGGAACTAACTCTGGCCAA---------GACGTG.........CTTGAAGTTGTCTTCTCTAAGCCCAATCGAGAGCGGCAGAAGCTGATGAGGGAACAGAATATTCTCAAGCAGATCTTCAAGCTGTTGCAGGCCCCCTTCACGGACTGC------GGGGATGGCCCGATG...---CTTCGGCTGGAGGAGCTGGGGGATCAGCGCCATGCTCCTTTCAGA................................................CATATTTGCCGACTCTGCTACAGGGTCCTGCGACACTCACAGCAAGACTACAGGAAGAACCAGGAGTACATAGCCAAGCAGTTTGGC------------------------TTCATGCAGAAGCAGATTGGCTATGACGTGCTGGCCGAAGACACCATCACTGCCCTGCTCCACAACAACCGGAAACTCCTGGAGAAGCACATCACCGCGGCAGAGATTGACACGTTTGTCAGCCTGGTGCGAAAG------...AACAGGGAGCCCAGGTTCTTGGATTACCTCTCTGACCTCTGCGTATCCATGAACAAGTCAATCCCTGTGACACAG------GAGCTCATCTGTAAAGCTGTGCTCAATCCCACCAAT---------------GCTGACATCCTGATTGAGACCAAGCTGGTTCTTTCTCGTTTTGAGTTT
TRN  10010101100011001
NAM  O77089_PANAR/461-675
ASQ  SLMLLLLDLLYFTAEKEHEQN--KSEslaLALEVTNPNRDRQKLLREQSILKQIFKILRAPFTETQGGDGP-.LLRIDELNDPRHSAYK................NIFRLCYRLLRLAQQGYRKNQEHIAQHFG--------FMQKQIGIDILAEETITALLHNNRKLLEIHITATEIETFVGLVRKNMhKWDWRFLDYLKVLCISNNQAIPRTQ--ELICKSVFSEKN-----KDILIETRLVEEDIEV
DSQ  TCGTTAATGCTGTTGCTTTTAGATCTACTGTATTTCACTGCTGAGAAGGAACATGAACAAAAC------AAGAGTGAAtcacttgcaTTGGCTCTGGAAGTCACTAATCCTAACAGAGATCGTCAGAAGCTTCTCAGAGAACAGAGTATTTTAAAACAGATTTTTAAGATTCTTAGAGCACCATTCACTGAAACTCAAGGAGGTGATGGTCCT---...CTCCTCCGGATTGATGAACTGAATGACCCACGACACTCTGCTTACAAG................................................AACATTTTTCGTCTGTGTTATAGACTCCTGAGGCTTGCCCAACAGGGTTATAGAAAAAACCAGGAACATATTGCACAACACTTTGGT------------------------TTTATGCAAAAACAAATTGGGATAGACATTTTGGCGGAAGAAACCATCACAGCTCTTCTTCATAACAACCGCAAACTACTGGAGATCCATATCACAGCTACAGAAATTGAAACATTTGTAGGATTGGTCCGGAAAAATATGcacAAATGGGACTGGAGATTCCTTGATTATCTTAAGGTTTTGTGCATTTCCAACAACCAAGCCATTCCCCGCACACAA------GAGCTGATATGTAAGAGTGTCTTCAGTGAGAAAAAC---------------AAAGACATTTTAATAGAGACAAGGTTGGTTGAGGAGGATATAGAAGTA
TRN  10010101100011000
NAM  IP3R_DROME/492-704
ASQ  ALISLLQDIVYFIAGMENEQ-NKTKA...LEFTIKNPIRDRQKLLREQYILKQLFKILQGPFQEHTAGDGPF.-LRLDELSDPKNSPYK................NIFRLCYRILRLSQQDYRKNQEYIAKHFG--------LMQKQIGYDILAEDTITALLHNNRKLLEKHITAAEIETFVGLVRKNMhNWDSRFLDYLSDLCVSNRKAIAVTQ--ELICKSVLSDKN-----KDILIETQVKALRTGS
DSQ  GCACTGATCTCGCTGCTGCAGGATATAGTGTACTTCATAGCCGGAATGGAAAACGAGCAG---AACAAGACAAAGGCT.........CTGGAATTCACCATCAAGAACCCAATCAGAGATCGGCAGAAATTGCTGCGCGAACAGTACATCCTTAAGCAGCTCTTCAAGATCTTACAGGGTCCTTTTCAGGAGCACACAGCCGGAGATGGTCCGTTC...---CTGCGGTTGGATGAGCTCAGTGATCCGAAGAACAGTCCTTACAAG................................................AATATCTTTCGTCTGTGCTACCGTATCCTGAGGTTGTCGCAACAGGATTACCGGAAGAACCAGGAGTACATTGCCAAGCACTTTGGC------------------------CTGATGCAGAAGCAGATCGGATACGATATTCTGGCAGAGGACACCATCACGGCCCTGCTGCACAACAACCGAAAGCTGCTGGAGAAGCACATAACAGCCGCAGAAATAGAAACCTTCGTCGGTCTGGTGCGGAAGAACATGcacAATTGGGACTCGCGGTTTCTCGACTACCTCTCAGACTTGTGCGTGTCCAATCGCAAGGCAATCGCTGTCACCCAG------GAGTTGATTTGCAAGAGCGTGCTGAGCGACAAGAAC---------------AAGGACATACTGATCGAGACGCAAGTAAAGGCACTGCGTACCGGATCC
TRN  10010101100011000
NAM  ITPR3_HUMAN/1171-1345
ASQ  IVKGILERLNKMCGVGE---------...------QMRKKQQRLLKNMDAHKVMLDLLQIPYDK--------.----------GDAKMM................EILRYTHQFLQKFCAGNPGNQALLHKHLH-----------LFLTPGLLEAETMQHIFLNNYQLCSEISEPV-LQHFVHLLATHG.-RHVQYLDFLHTVIKAEGKYVKKCQ--DMIMTELTNAGD------DVVVFYNDKASLAHL
DSQ  ATCGTCAAGGGCATCCTGGAAAGGCTGAACAAGATGTGCGGGGTTGGGGAG---------------------------.........------------------CAAATGAGGAAGAAGCAGCAACGGCTGCTGAAGAACATGGATGCCCACAAGGTCATGCTGGACCTGCTGCAGATCCCCTATGACAAG------------------------...------------------------------GGTGATGCCAAGATGATG................................................GAGATCCTGCGCTACACGCACCAGTTCCTGCAGAAGTTCTGTGCAGGGAACCCCGGCAACCAGGCCCTGCTGCACAAACACCTGCAC---------------------------------CTCTTCCTCACGCCAGGGCTCCTGGAGGCAGAGACCATGCAGCACATCTTCCTGAACAACTATCAGCTCTGCTCCGAGATCAGCGAGCCTGTG---TTGCAGCACTTCGTGCACCTGCTGGCCACGCACGGG...---CGCCATGTGCAGTACCTGGACTTCCTGCACACCGTCATTAAGGCCGAGGGCAAGTACGTCAAGAAGTGCCAG------GACATGATCATGACTGAGCTGACCAATGCAGGTGAC------------------GATGTGGTCGTGTTCTACAATGATAAGGCATCGCTGGCCCACCTG
TRN  10010101100011011
NAM  ITPR2_HUMAN/1181-1355
ASQ  IVKEILIRLSKLCVQNK---------...------KCRNQHQRLLKNMGAHSVVLDLLQIPYEK--------.----------NDEKMN................EVMNLAHTFLQNFCRGNPQNQVLLHKHLN-----------LFLTPGLLEAETMRHIFMNNYHLCNEISERV-VQHFVHCIETHG.-RHVEYLRFLQTIVKADGKYVKKCQ--DMVMTELINGGE------DVLIFYNDRASFPIL
DSQ  ATTGTAAAGGAGATTTTGATCAGGCTAAGTAAACTCTGTGTGCAGAATAAA---------------------------.........------------------AAGTGTCGGAATCAACATCAACGATTACTGAAAAATATGGGGGCGCATTCGGTGGTGTTGGATCTTCTGCAGATACCCTATGAAAAG------------------------...------------------------------AATGATGAAAAGATGAAT................................................GAAGTAATGAATCTAGCCCATACATTTCTGCAGAATTTCTGTCGAGGAAATCCACAGAATCAAGTTCTTCTTCATAAACATCTGAAT---------------------------------TTGTTTTTAACTCCAGGTCTCCTTGAAGCAGAAACCATGCGGCACATCTTCATGAACAATTACCATCTGTGCAACGAAATTAGCGAGAGAGTT---GTACAACACTTTGTGCACTGCATTGAGACACATGGC...---CGCCACGTGGAGTACCTGAGGTTTTTGCAAACAATTGTAAAAGCAGATGGTAAATATGTGAAGAAATGCCAG------GATATGGTAATGACAGAGTTGATAAATGGGGGTGAA------------------GACGTGCTGATATTTTACAATGATAGAGCATCATTTCCAATCCTT
TRN  10010101100011000
NAM  ITPR1_MOUSE/1175-1354
ASQ  VVKEILIRLSKLCVQESASVR-----...------KSRKQQQRLLRNMGAHAVVLELLQIPYEKA-------.----------EDTKMQ................EIMRLAHEFLQNFCAGNQQNQALLHKHIN-----------LFLKPGILEAVTMQHIFMNNFQLCSEINERV-VQHFVHCIETHG.-RNVQYIKFLQTIVKAEGKFIKKCQ--DMVMAELVNSGE------DVLVFYNDRASFQTL
DSQ  GTGGTGAAAGAGATTTTGATTCGACTTAGCAAGCTCTGCGTGCAGGAGAGCGCGTCGGTGAGG---------------.........------------------AAGAGCCGGAAGCAGCAGCAACGACTGCTGAGGAACATGGGCGCACACGCTGTGGTGCTGGAGCTGCTGCAGATCCCCTACGAGAAGGCC---------------------...------------------------------GAAGACACAAAGATGCAA................................................GAGATCATGCGGCTGGCTCATGAATTTTTGCAGAATTTCTGTGCAGGCAACCAGCAGAATCAAGCTTTGCTGCATAAACACATAAAC---------------------------------CTGTTTCTCAAGCCAGGGATCCTGGAGGCAGTGACGATGCAGCACATCTTCATGAACAACTTCCAGCTGTGCAGTGAGATCAACGAGAGAGTG---GTCCAGCACTTTGTTCACTGCATAGAGACCCACGGT...---CGAAACGTCCAGTATATCAAGTTTCTCCAGACGATTGTCAAGGCAGAAGGGAAATTCATTAAAAAGTGCCAA------GACATGGTCATGGCTGAGCTTGTCAACTCTGGAGAG------------------GACGTCCTCGTGTTCTACAATGACAGAGCCTCTTTCCAGACTCTG
TRN  10010101100011011
NAM  O77089_PANAR/1214-1394
ASQ  RIQQILVRMNKLCVTQSSHGN-----...-----LSPKRNEQRLLRNMGIHSVVLELLQIPYDRK-------.----------EDKRMN................ELIELAHQFLQNFCLGDRANQALLYKSID-----------LFLNPGLLEAKTVCAVFKDNSHLCSEVSERV-IQHFIHCIETHG.-RHVQYLKFLQTIVKAEGQFLRRSQ--DIVMQELVNAGE------DVLVFYNERASFNMF
DSQ  CGTATTCAACAGATTTTAGTGAGGATGAATAAGCTGTGTGTCACACAGTCCAGTCATGGTAAT---------------.........---------------CTGTCTCCCAAGAGGAATGAACAGCGGCTTCTGCGGAACATGGGCATCCATTCTGTTGTTTTGGAGCTGTTGCAAATTCCCTATGACAGAAAG---------------------...------------------------------GAAGATAAACGTATGAAT................................................GAATTAATTGAGCTTGCCCATCAGTTTCTTCAAAACTTTTGCCTTGGTGATCGGGCAAATCAAGCCTTGCTGTATAAAAGCATTGAT---------------------------------CTCTTCCTCAACCCAGGGTTGCTAGAAGCCAAGACAGTGTGTGCCGTTTTTAAGGATAACTCCCACCTGTGCAGTGAAGTATCAGAACGGGTC---ATACAACACTTCATTCACTGTATCGAGACTCATGGC...---CGACATGTTCAGTACTTGAAGTTTCTCCAAACCATTGTCAAAGCAGAAGGACAGTTCCTCCGTAGAAGTCAG------GATATTGTTATGCAGGAGCTGGTGAATGCTGGTGAA------------------GATGTGCTTGTATTCTACAATGAAAGGGCTTCATTCAACATGTTT
TRN  10010101100011000
NAM  IP3R_DROME/1275-1456
ASQ  KVKEILIRMNKFCVTASGPGS-----...----VVKPRKHEQRLLRNVGVHTVVLDLLQNPYDEK-------.----------DDELMK................ELMCLAHEFLQNFCLGNQQNQVLLHNHLD-----------LFLNPGILEAKTVCAIFKDNLALCNEVTDKV-VQHFVHCIEIHG.-RHVAYLQFLQTVVAAENQFIRRCQ--DMVMQELINSGE------DVLVFYNDKGSFNHF
DSQ  AAGGTCAAGGAGATTCTGATCCGCATGAACAAATTTTGCGTAACTGCATCCGGTCCGGGTTCG---------------.........------------GTGGTCAAGCCACGCAAGCATGAGCAACGACTGCTCCGCAATGTTGGCGTCCACACTGTCGTCCTCGATCTCCTCCAGAATCCGTACGACGAGAAG---------------------...------------------------------GACGACGAGCTGATGAAG................................................GAGCTCATGTGCCTGGCCCACGAGTTCCTGCAGAACTTCTGCCTGGGCAATCAACAGAACCAGGTCCTGCTGCACAACCATCTCGAT---------------------------------CTGTTCCTGAATCCGGGCATTCTGGAGGCGAAGACTGTGTGCGCCATCTTCAAGGACAACTTGGCCCTGTGCAACGAGGTGACGGACAAGGTG---GTGCAGCACTTCGTGCACTGCATCGAGATTCATGGT...---CGTCACGTAGCCTACCTGCAGTTCCTGCAGACCGTAGTGCGGGCGGAGAACCAGTTCATCCGCCGCTGCCAG------GACATGGTGATGCAGGAGCTCATCAACTCCGGCGAG------------------GATGTGCTGGTCTTCTACAACGACAAGGGTTCTTTTAACCACTTC
TRN  11011101101011011
NAM  P91905_CAEEL/2240-2464
ASQ  VYLIQIRELLTVQFEHTEEAILKRGL...WKLMNNRIFFQHPDLMRLLSVHENVMSIMMNILTAQQGTVEHE.-------GDELKEKAPik...........dasEMVVACSRFLCYFCRTSRQNQKAMFEHLSFLLDNATMLLARPSLRGSVPLDVAYSSFMDNNELALALKEEE-LDKVAVYLSRCG.-LQPNSELITKGYPDIGWDPVEGERYIDFLRFCVWINGENVEENANLVIRLLIRRPECLG
DSQ  GTGTACCTCATACAAATCCGCGAGCTTCTTACCGTACAATTTGAGCATACTGAAGAGGCAATTCTGAAGAGAGGATTG.........TGGAAGTTGATGAACAACAGGATATTCTTCCAACATCCAGATCTGATGAGACTTCTTTCAGTCCACGAAAATGTAATGTCTATTATGATGAACATTCTCACAGCTCAGCAGGGAACCGTCGAACATGAA...---------------------GGAGATGAATTGAAAGAGAAAGCACCAatcaag.................................gatgcatctGAAATGGTCGTTGCATGTTCCAGATTCCTTTGCTATTTCTGCAGAACATCCCGTCAAAATCAAAAAGCAATGTTCGAACATCTATCATTCCTTCTTGACAATGCAACTATGCTTCTTGCAAGACCATCTTTGAGAGGATCAGTTCCACTTGATGTTGCCTACTCATCGTTTATGGATAACAATGAACTCGCTCTTGCTCTCAAAGAAGAAGAA---CTTGATAAAGTAGCCGTCTACTTGTCGAGATGTGGA...---TTGCAGCCGAACTCGGAATTGATCACTAAGGGATATCCAGATATTGGATGGGATCCAGTTGAAGGCGAAAGATACATCGATTTCCTGAGATTCTGTGTCTGGATCAATGGGGAAAACGTGGAAGAAAATGCAAATCTTGTCATTCGTCTGCTGATTCGCAGACCCGAATGCCTTGGT
TRN  10010101100011001
NAM  RY44_DROME/2224-2453
ASQ  VGLSQIRALLPVQMSQEEEELMRKRL...WKLVNNATFFQHPDLIRILRVHENVMAVMMNTLGRR-------.------AQAQSDAPTQsevaegapskekdtshEMVVACCRFLCYFCRTGRQNQKAMFDHFDFLLDNANILLARPSLRGSTPLDVAYSSLMENTELALALREHY-LEKIAVYLSRCG.-LQSNSELVEKGYPDLGWDPVEGERYLDFLRYCVWVNGESVEENANLVIRLLIRRPECLG
DSQ  GTGGGCCTCAGCCAGATTCGCGCCCTGCTGCCCGTCCAGATGAGCCAGGAAGAGGAGGAACTGATGCGCAAGCGGCTG.........TGGAAGCTGGTTAACAACGCCACCTTCTTTCAGCACCCGGACCTCATACGCATCCTGCGTGTCCACGAGAACGTGATGGCAGTGATGATGAACACACTCGGACGGAGG---------------------...------------------GCACAGGCACAAAGCGATGCGCCCACCCAGtcggaggtagccgaaggagctccgtccaaggagaaggacacctcccacGAAATGGTGGTAGCTTGCTGCCGATTCCTCTGCTACTTCTGTCGCACTGGTCGCCAAAACCAAAAGGCCATGTTTGATCACTTCGACTTTCTGCTGGACAACGCCAACATCCTGCTGGCACGGCCAAGCCTGCGAGGATCCACGCCCCTCGATGTGGCATACTCGAGTTTGATGGAGAACACAGAATTGGCTCTGGCCCTGAGGGAACACTAT---CTAGAAAAGATCGCCGTCTACCTCTCGCGATGCGGA...---CTACAGAGCAACTCGGAGCTCGTGGAGAAGGGCTATCCGGATCTGGGTTGGGATCCCGTCGAAGGTGAGCGTTACCTGGACTTCCTGCGCTATTGCGTTTGGGTCAACGGCGAGAGCGTCGAGGAGAATGCGAACCTTGTCATTCGACTTCTTATCCGTCGTCCGGAATGCTTGGGA
TRN  10010101100011011
NAM  RYR1_PIG/2158-2366
ASQ  ECLGQIRSLLIVQMGPQEENLMIQSI...GNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLG---------.------GGESKEIRFP................KMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLG---MQGSTPLDVAAASVIDNNELALALQEQD-LEKVVSYLAGCG.-LQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFG
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