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PANDIT
Protein and Associated NucleotideDomains with Inferred Trees
(View summary and phylogenies for PF01007 - IRK)
FAM  PF01007
PID  IRK
DES  Inward rectifier potassium channel
IPR  IPR001838
ANO  14
ALN  378
AID  0.483213
APH  ((((((Q21458_CAEEL/84-424:0.37518,IRK1_CAEEL/77-422:0.46246):0.23387,(IRK16_RAT/37-358:0.61218,((IRK4_HUMAN/22-377:0.19641,IRK12_HUMAN/47-380:0.11188):0.07239,IRK2_CAVPO/48-380:0.12315):0.10783):0.09366):0.07161,(IRK3_CHICK/39-385:0.27917,(IRK5_HUMAN/54-390:0.14248,IRK9_HUMAN/25-362:0.20866):0.11934):0.21309):0.08843,(IRK8_HUMAN/37-380:0.14868,IRK11_HUMAN/36-368:0.16741):0.34609):0.28756,IRK1_HUMAN/43-380:0.32208):0.30220,IRK10_HUMAN/31-369:0.21285,IRK15_HUMAN/30-365:0.23990);
ATP  ((((((Q21458_CAEEL/84-424,IRK1_CAEEL/77-422),(IRK16_RAT/37-358,((IRK4_HUMAN/22-377,IRK12_HUMAN/47-380),IRK2_CAVPO/48-380))),(IRK3_CHICK/39-385,(IRK5_HUMAN/54-390,IRK9_HUMAN/25-362))),(IRK8_HUMAN/37-380,IRK11_HUMAN/36-368)),IRK1_HUMAN/43-380),IRK10_HUMAN/31-369,IRK15_HUMAN/30-365);
ATL  5.54231
DNO  12
DLN  1134
DID  0.575978
DPH  (((((IRK4_HUMAN/22-377:0.14198,IRK12_HUMAN/47-380:0.08018):0.03812,(IRK16_RAT/37-358:0.42795,IRK2_CAVPO/48-380:0.19210):0.08637):0.10213,((IRK8_HUMAN/37-380:0.25260,IRK11_HUMAN/36-368:0.12916):0.21805,(IRK3_CHICK/39-385:0.21228,(IRK5_HUMAN/54-390:0.16809,IRK9_HUMAN/25-362:0.17381):0.05914):0.08559):0.05137):0.20853,IRK1_HUMAN/43-380:0.31573):0.17040,IRK10_HUMAN/31-369:0.21579,IRK15_HUMAN/30-365:0.22341);
DTP  (((((IRK4_HUMAN/22-377,IRK12_HUMAN/47-380),(IRK16_RAT/37-358,IRK2_CAVPO/48-380)),((IRK8_HUMAN/37-380,IRK11_HUMAN/36-368),(IRK3_CHICK/39-385,(IRK5_HUMAN/54-390,IRK9_HUMAN/25-362)))),IRK1_HUMAN/43-380),IRK10_HUMAN/31-369,IRK15_HUMAN/30-365);
DTL  3.55278
RID  0.49695
RPH  ((IRK8_HUMAN/37-380:0.15124,IRK11_HUMAN/36-368:0.16229):0.35530,((IRK16_RAT/37-358:0.60427,((IRK4_HUMAN/22-377:0.19444,IRK12_HUMAN/47-380:0.11212):0.07587,IRK2_CAVPO/48-380:0.11743):0.10672):0.13252,(IRK3_CHICK/39-385:0.28202,(IRK5_HUMAN/54-390:0.14279,IRK9_HUMAN/25-362:0.20595):0.11357):0.18740):0.11378,(IRK1_HUMAN/43-380:0.30463,(IRK10_HUMAN/31-369:0.21839,IRK15_HUMAN/30-365:0.23722):0.32060):0.28474);
RTP  ((IRK8_HUMAN/37-380,IRK11_HUMAN/36-368),((IRK16_RAT/37-358,((IRK4_HUMAN/22-377,IRK12_HUMAN/47-380),IRK2_CAVPO/48-380)),(IRK3_CHICK/39-385,(IRK5_HUMAN/54-390,IRK9_HUMAN/25-362))),(IRK1_HUMAN/43-380,(IRK10_HUMAN/31-369,IRK15_HUMAN/30-365)));
RTL  4.42329
LNK  IRK10_HUMAN/31-369:P78508:U73192
LNK  IRK11_HUMAN/36-368:Q14654:D50582
LNK  IRK12_HUMAN/47-380:Q14500:L36069
LNK  IRK15_HUMAN/30-365:Q99712:U73191
LNK  IRK16_RAT/37-358:P52191:X83581
LNK  IRK1_CAEEL/77-422:P52192:
LNK  IRK1_HUMAN/43-380:P48048:U12541
LNK  IRK2_CAVPO/48-380:P52185:Z48971
LNK  IRK3_CHICK/39-385:Q90854:L35555
LNK  IRK4_HUMAN/22-377:P48050:U07364
LNK  IRK5_HUMAN/54-390:P48544:U39195
LNK  IRK8_HUMAN/37-380:Q15842:D50312
LNK  IRK9_HUMAN/25-362:Q92806:U52152
LNK  Q21458_CAEEL/84-424:Q21458:
AMK  xxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..............xxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxx
DMK  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..........................................xxxxxxxxxxxxxxxxxxxxxxxx..................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
NAM  IRK1_CAEEL/77-422
ASQ  VGKNGICNVYNTNVPKK.DRQYLRDIFTTMIDVKWRWMLMLFASAFVLSWSIFGTTYYLIALVHGDLSLP-..............-TPVNHTA......CVMNLDSVYSSFLFAVETHHTIGYGHRYITTECYLAGAIVCLQAICALLLQSFMVGIVFAKMARPKKRAETIIFSDKAVICLRDGQLCFLCRVGDMRNTHLVEAHVRLQFITDRETNEGEIEPLHQFEMKVGPSIADdDRLFLVWPTTLCHVIDSRSPLYNYNQQTLMS.AQFEIIVLLEGIVESTGMTAQAKTSYLPSEVLWGHRFRKLVTYQRSNGSYQIDYDLFHSTYPVR--..TPAMSPAEFYSSKP-.--NLKDYYCHDSHEHKLEDNRSSDS
NAM  Q21458_CAEEL/84-424
ASQ  VQKQGLCNISLKNVPKQ.RRKYFSDIFTTVIEMKWRWCLLYFSLSFMISWSFFATVYFLIAKQHGDIEQIA..............--NATWTP......CIVNVHNELNAFLFSFTTQTTIGYGFRYPTDACPLTIVTMCFQFMWGVMTQTLMAGIIFSKLARPIKRAATLIFSKNAVICLRDGKLCLLFRVGDMRKSSLAEAHVRLQMIKRCVTYEGELLPFHQFDMDVGYDQGL.DRVFVIWPITICHEIDERSPLWEIGADDLKS.AKFEIIAILEGVVESVGSTTQARTSYLPSEILWGHRFEKLVHYKKENGQYNIDFGKFHNVYSVN--..TPTCSAAEIERLRS-.EGIFNESEYQMYP------PSDNKL
NAM  IRK12_HUMAN/47-380
ASQ  VKKNGQCNIEFANMDEK.SQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAE..............--GRGRTP......CVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGL.DRIFLVSPITILHEIDEASPLFGIS-QDLET.DDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFE--EKNQYKIDYSHFHKTYEVPS-..TPRCSAKDLVENKF-.--LLPSAN---------SFCYENEL
DSQ  GTCAAGAAGAATGGCCAGTGCAACATTGAGTTCGCCAACATGGACGAGAAG...TCACAGCGCTACCTGGCTGACATGTTCACCACCTGTGTGGACATCCGCTGGCGGTACATGCTGCTCATCTTCTCGCTGGCCTTCCTTGCCTCCTGGCTGCTGTTCGGCATCATCTTCTGGGTCATCGCGGTGGCACACGGTGACCTGGAGCCGGCTGAG..........................................------GGCCGGGGCCGCACACCC..................TGTGTGATGCAGGTGCACGGCTTCATGGCGGCCTTCCTCTTCTCCATCGAGACGCAGACCACCATCGGCTACGGGCTGCGCTGTGTGACGGAGGAGTGCCCGGTGGCCGTCTTCATGGTGGTGGCCCAGTCCATCGTGGGCTGCATCATCGACTCCTTCATGATTGGTGCCATCATGGCCAAGATGGCAAGGCCCAAGAAGCGGGCACAGACGCTGCTGTTCAGCCACAACGCCGTGGTGGCCCTGCGTGACGGCAAGCTCTGCCTCATGTGGCGTGTGGGTAACCTGCGCAAGAGCCACATTGTGGAGGCCCATGTGCGCGCGCAGCTCATCAAGCCGCGGGTCACCGAGGAGGGCGAGTACATCCCGCTGGACCAGATCGACATCGATGTGGGCTTCGACAAGGGCCTG...GACCGCATCTTTCTGGTGTCGCCCATCACCATCTTGCATGAGATTGACGAGGCCAGCCCGCTCTTCGGCATCAGC---CAGGACCTGGAGACG...GACGACTTTGAGATCGTGGTCATCCTGGAAGGCATGGTGGAGGCCACAGCCATGACCACCCAGGCCCGCAGCTCCTACCTGGCCAATGAGATCCTGTGGGGTCACCGCTTTGAGCCCGTGCTCTTCGAG------GAGAAGAACCAGTACAAGATTGACTACTCGCACTTCCACAAGACCTATGAGGTGCCCTCT---......ACGCCCCGCTGCAGTGCGAAGGATCTGGTAGAGAACAAGTTC---...------CTGCTGCCCAGCGCCAAC---------------------------TCCTTCTGCTACGAGAACGAGCTG
TRN  10010101100011001
NAM  IRK2_CAVPO/48-380
ASQ  VKKDGHCNVQFINVGEK.GQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDAS-..............---KESKA......CVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGI.DRIFLVSPITIVHEIDEDSPLYDLSKQDIDN.ADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFE--EKHYYKVDYSRFHKTYEVPN-..TPLCSARDLAEKKY-.--ILSNAN---------SFCYENEV
DSQ  GTGAAGAAAGATGGCCACTGTAATGTTCAGTTCATCAACGTTGGGGAAAAG...GGACAACGGTACCTTGCTGACATTTTTACTACGTGTGTGGACATTCGCTGGCGGTGGATGCTGGTTATCTTTTGCCTAGCTTTTGTTCTCTCGTGGCTGTTTTTTGGCTGTGTGTTTTGGCTGATAGCTTTGCTCCATGGAGATCTGGATGCATCT---..........................................---------AAGGAGAGCAAAGCC..................TGTGTGTCTGAGGTCAACAGCTTCACAGCTGCCTTTCTTTTCTCCATTGAGACCCAGACAACCATCGGCTATGGGTTCCGATGTGTCACGGATGAATGCCCGATTGCGGTGTTCATGGTTGTGTTCCAGTCAATTGTGGGCTGCATTATTGATGCTTTTATCATTGGTGCCGTCATGGCAAAGATGGCAAAGCCAAAGAAAAGAAATGAGACTCTTGTCTTCAGTCACAATGCTGTGATTGCCATGAGAGATGGCAAGCTGTGTTTGATGTGGCGAGTAGGCAACCTTCGGAAAAGCCACTTGGTAGAAGCTCATGTTCGAGCCCAGCTCCTCAAATCCAGAATTACTTCTGAAGGGGAATACATCCCCTTGGATCAAATAGACATCAATGTTGGCTTTGACAGTGGAATT...GACCGTATATTTCTGGTATCCCCAATCACTATTGTCCATGAAATAGATGAAGATAGTCCTTTATATGATTTGAGCAAGCAGGACATTGATAAT...GCAGACTTTGAAATTGTTGTGATACTAGAAGGCATGGTGGAAGCCACTGCCATGACAACACAGTGTCGTAGTTCTTATTTGGCCAACGAGATCCTTTGGGGCCACCGCTATGAGCCAGTGCTCTTTGAG------GAGAAGCACTACTATAAAGTGGACTATTCGAGGTTTCATAAGACTTACGAAGTACCCAAC---......ACTCCCCTTTGTAGTGCCAGAGACTTAGCAGAAAAGAAATAT---...------ATTCTCTCAAATGCTAAC---------------------------TCATTTTGCTATGAAAATGAAGTT
TRN  10010101100011000
NAM  IRK4_HUMAN/22-377
ASQ  VKKNGQCNVYFANLSNK.SQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPgvpaaggpaaggggAAPVAPKP......CIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGL.DRIFLVSPIIIVHEIDEDSPLYGMGKEELES.EDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFE--EKSHYKVDYSRFHKTYEVAG-..TPCCSARELQESKI-.--TVLPAPPPPP----SAFCYENEL
DSQ  GTCAAGAAGAACGGCCAATGCAACGTGTACTTCGCCAACCTGAGCAACAAG...TCGCAGCGCTACATGGCGGACATCTTCACCACCTGCGTGGACACGCGCTGGCGCTACATGCTCATGATCTTCTCCGCGGCCTTCCTTGTCTCCTGGCTCTTTTTCGGCCTCCTCTTCTGGTGTATCGCCTTCTTCCACGGTGACCTGGAGGCCAGCCCAggggtgcctgcggcggggggcccggcggcgggtggtggcggaGCAGCCCCGGTGGCCCCCAAGCCC..................TGCATCATGCACGTGAACGGCTTCCTGGGTGCCTTCCTGTTCTCGGTGGAGACGCAGACGACCATCGGCTATGGGTTCCGGTGCGTGACAGAGGAGTGCCCGCTGGCAGTCATCGCTGTGGTGGTCCAGTCCATCGTGGGCTGCGTCATCGACTCCTTCATGATTGGCACCATCATGGCCAAGATGGCGCGGCCCAAGAAGCGGGCGCAGACGTTGCTGTTCAGCCACCACGCGGTCATTTCGGTGCGCGACGGCAAGCTCTGCCTCATGTGGCGCGTGGGCAACCTGCGCAAGAGCCACATTGTGGAGGCCCACGTGCGGGCCCAGCTCATCAAGCCCTACATGACCCAGGAGGGCGAGTACCTGCCCCTGGACCAGCGGGACCTCAACGTGGGCTATGACATCGGCCTG...GACCGCATCTTCCTGGTGTCGCCCATCATCATTGTCCACGAGATCGACGAGGACAGCCCGCTTTATGGCATGGGCAAGGAGGAGCTGGAGTCG...GAGGACTTTGAGATCGTGGTCATCCTGGAGGGCATGGTGGAGGCCACGGCCATGACCACCCAGGCCCGCAGCTCCTACCTGGCCAGCGAGATCCTGTGGGGCCACCGCTTTGAGCCTGTGGTCTTCGAG------GAGAAGAGCCACTACAAGGTGGACTACTCACGTTTTCACAAGACCTACGAGGTGGCCGGC---......ACGCCCTGCTGCTCGGCCCGGGAGCTGCAGGAGAGTAAGATC---...------ACCGTGCTGCCCGCCCCACCGCCCCCTCCC------------AGTGCCTTCTGCTACGAGAACGAGCTG
TRN  11011111101111101
NAM  IRK9_HUMAN/25-362
ASQ  VEKDGRCNVQQGNVR-E.TYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEH--..............LEDTAWTP......CVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGD.DRLFLVSPLVISHEIDAASPFWEASRRALER.DDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTL--EDGFYEVDYASFHETFEVP--..TPSCSARELAEAAARlDAHLYWSIPSR--------LDEKVE
DSQ  GTGGAGAAGGATGGCCGGTGCAACGTGCAGCAGGGCAACGTGCGC---GAG...ACATACCGCTACCTGACGGACCTGTTCACCACGCTGGTGGACCTGCAGTGGCGCCTCAGCCTGTTGTTCTTCGTCCTGGCCTACGCGCTCACCTGGCTCTTCTTCGGCGCCATCTGGTGGCTGATCGCCTACGGCCGCGGCGACCTGGAGCAC------..........................................CTGGAGGACACCGCGTGGACGCCG..................TGCGTCAACAACCTCAACGGCTTCGTGGCCGCCTTCCTCTTCTCCATCGAGACCGAGACCACCATCGGCTACGGGCACCGCGTCATCACCGACCAGTGCCCCGAGGGCATCGTGCTGCTGCTGCTGCAGGCCATCCTGGGCTCCATGGTGAACGCCTTCATGGTGGGCTGCATGTTCGTCAAGATCTCGCAGCCCAACAAGCGCGCAGCCACGCTCGTCTTCTCCTCGCACGCCGTGGTGTCGCTGCGCGACGGGCGCCTCTGCCTCATGTTCCGCGTGGGCGACTTGCGCTCCTCACACATAGTGGAGGCCTCCATCCGCGCCAAGCTCATCCGCTCGCGCCAGACGCTGGAGGGCGAGTTCATCCCGCTGCACCAGACCGACCTCAGCGTGGGCTTCGACACGGGAGAC...GACCGCCTCTTCCTCGTCTCGCCGCTGGTTATCAGCCACGAGATCGACGCCGCCAGCCCCTTCTGGGAGGCGTCGCGCCGTGCCCTCGAGAGG...GACGACTTCGAGATCGTCGTTATCCTCGAGGGCATGGTGGAAGCCACGGGAATGACATGCCAAGCTCGGAGCTCCTACCTGGTAGACGAGGTGCTGTGGGGCCACCGCTTCACGTCAGTGCTGACTCTG------GAGGACGGCTTCTACGAAGTGGACTATGCCAGCTTTCACGAGACTTTTGAGGTGCCC------......ACACCTTCGTGCAGTGCTCGAGAGCTGGCAGAGGCTGCCGCCCGCcttGATGCCCATCTCTACTGGTCCATCCCCAGCCGG------------------------CTGGATGAGAAGGTGGAG
TRN  10010101100011001
NAM  IRK5_HUMAN/54-390
ASQ  MEKSGKCNVHHGNVQ-E.TYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDH--..............VGDQEWIP......CVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGD.DRLFLVSPLIISHEINEKSPFWEMSQAQLHQ.EEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTL--EKGFYEVDYNTFHDTYETN--..TPSCCAKELAEMKR-.EGRLLQYLPSPP-------LLGGCA
DSQ  ATGGAGAAGAGCGGCAAGTGCAACGTGCACCACGGCAACGTCCAG---GAG...ACCTACCGGTACCTGAGTGACCTCTTCACCACCCTGGTGGACCTCAAGTGGCGCTTCAACTTGCTCGTCTTCACCATGGTTTACACTGTCACCTGGCTGTTCTTCGGCTTCATTTGGTGGCTCATTGCTTATATCCGGGGTGACCTGGACCAT------..........................................GTTGGCGACCAAGAGTGGATTCCT..................TGTGTTGAAAACCTCAGTGGCTTCGTGTCCGCTTTCCTGTTCTCCATTGAGACCGAAACAACCATTGGGTATGGCTTCCGAGTCATCACAGAGAAGTGTCCAGAGGGGATTATACTCCTCTTGGTCCAGGCCATCCTGGGCTCCATCGTCAATGCCTTCATGGTGGGGTGCATGTTTGTCAAGATCAGCCAGCCCAAGAAGAGAGCGGAGACCCTCATGTTTTCCAACAACGCAGTCATCTCCATGCGGGACGAGAAGCTGTGCCTCATGTTCCGGGTGGGCGACCTCCGCAACTCCCACATCGTGGAGGCCTCCATCCGGGCCAAGCTCATCAAGTCCCGGCAGACCAAAGAGGGGGAGTTCATCCCCCTGAACCAGACAGACATCAACGTGGGCTTTGACACGGGCGAC...GACCGCCTCTTCCTGGTGTCTCCTCTGATCATCTCCCACGAGATCAACGAGAAGAGCCCTTTCTGGGAGATGTCTCAGGCTCAGCTGCATCAG...GAAGAGTTTGAAGTTGTGGTCATTCTAGAAGGGATGGTGGAAGCCACAGGCATGACCTGCCAAGCCCGGAGCTCCTACATGGATACAGAGGTGCTCTGGGGCCACCGATTCACACCAGTCCTCACCTTG------GAAAAGGGCTTCTATGAGGTGGACTACAACACCTTCCATGATACCTATGAGACCAAC------......ACACCCAGCTGCTGTGCCAAGGAGCTGGCAGAAATGAAGAGG---...GAAGGCCGGCTCCTCCAGTACCTCCCCAGCCCCCCA---------------------CTGCTGGGGGGCTGTGCT
TRN  10010101100011011
NAM  IRK3_CHICK/39-385
ASQ  VDKNGRCNVQHGNLGGE.TSRYLSDLFTTLVDLKWRWNLFIFVLTYTVAWLFMASMWWVIAYMRGDLNK--..............AHDDSYTP......CVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAAISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGA.DQLFLVSPLTICHVIDAKSPFYDLSQRTMQT.EQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL--EEGFFKVDYSQFHATFEVP--..TPPYSVKEQEEMLLMsSPLIAPAVSNSKERNNSVECLDGLD
DSQ  GTGGATAAGAACGGGAGGTGCAACGTGCAGCACGGGAACCTGGGCGGCGAG...ACCAGCCGGTACCTGTCCGACCTCTTCACCACGCTGGTGGACCTCAAGTGGCGCTGGAACCTCTTCATTTTCGTCCTCACCTACACCGTGGCCTGGCTCTTCATGGCCTCCATGTGGTGGGTGATCGCCTACATGCGGGGCGACCTGAACAAG------..........................................GCTCACGACGACAGCTACACCCCC..................TGCGTGGCCAACGTCTACAACTTCCCTTCCGCCTTCCTCTTCTTCATCGAGACCGAGGCCACCATCGGCTACGGCTACCGCTACATCACGGACAAATGCCCCGAGGGCATCATCCTCTTCCTCTTCCAGTCCATCCTGGGCTCCATCGTGGACGCCTTCCTCATCGGCTGCATGTTCATCAAGATGTCCCAGCCCAAGAAGAGGGCTGAGACGCTGATGTTCAGCGAGCACGCGGCCATCTCCATGCGGGACGGCAAGCTCACCCTCATGTTCCGCGTGGGGAACCTCCGCAACAGCCATATGGTCTCAGCGCAGATCCGCTGCAAGCTGCTCAAGTCCCGCCAGACGCCCGAGGGTGAGTTCCTGCCGCTGGACCAGCTGGAGCTGGACGTGGGCTTCAGCACAGGTGCC...GACCAGCTCTTCCTCGTCTCGCCGCTCACCATCTGCCACGTCATCGATGCCAAGAGCCCCTTCTATGACCTGTCCCAGCGCACGATGCAGACG...GAGCAGTTCGAGATCGTCGTCATCCTGGAGGGCATCGTGGAAACCACGGGGATGACGTGCCAGGCCAGGACATCCTACACTGAGGATGAGGTGCTCTGGGGCCATCGCTTCTTCCCTGTTATATCCTTG------GAAGAAGGGTTCTTCAAAGTCGACTACTCGCAGTTCCACGCGACGTTTGAGGTCCCC------......ACGCCGCCGTACAGCGTGAAGGAGCAGGAGGAGATGCTGCTCATGtccTCACCCCTGATAGCGCCCGCTGTCAGCAACAGCAAGGAGAGGAATAACTCGGTGGAGTGCCTGGATGGTCTGGAT
TRN  10010101100011001
NAM  IRK11_HUMAN/36-368
ASQ  VSKKGNCNVAHKNIR-E.QGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMAWWLIAFAHGDLAP--..............-SEGTAEP......CVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILSLIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGG.NSIFLVAPLIIYHVIDANSPLYDLAPSDLHHhQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAE--EDGRYSVDYSKFGNTIKVP--..TPLCTARQLDEDHS-.---LLEALTLA--------SARGPL
DSQ  GTGTCCAAGAAAGGCAACTGCAACGTGGCCCACAAGAACATCCGG---GAG...CAGGGCCGCTTCCTGCAGGACGTGTTCACCACGCTGGTGGACCTCAAGTGGCCACACACATTGCTCATCTTCACCATGTCCTTCCTGTGCAGCTGGCTGCTCTTCGCCATGGCCTGGTGGCTCATCGCCTTCGCCCACGGTGACCTGGCCCCC------..........................................---AGCGAGGGCACTGCTGAGCCC..................TGTGTCACCAGCATCCACTCCTTCTCGTCTGCCTTCCTTTTCTCCATTGAGGTCCAAGTGACTATTGGCTTTGGGGGGCGCATGGTGACTGAGGAGTGCCCACTGGCCATCCTGAGCCTCATCGTGCAGAACATCGTGGGGCTCATGATCAACGCCATCATGCTTGGCTGCATCTTCATGAAGACTGCCCAAGCCCACCGCAGGGCTGAGACCCTCATCTTCAGCAAGCATGCGGTGATCGCTCTGCGCCACGGCCGCCTCTGCTTCATGCTACGTGTGGGTGACCTCCGCAAGAGCATGATCATCAGCGCCACCATCCACATGCAGGTGGTACGCAAGACCACCAGCCCCGAGGGCGAGGTGGTGCCCCTCCACCAGGTGGACATCCCCATGGAGAACGGCGTGGGTGGC...AACAGCATCTTCCTGGTGGCCCCGCTGATCATCTACCATGTCATTGATGCCAACAGCCCACTCTACGACCTGGCACCCAGCGACCTGCACCACcacCAGGACCTCGAGATCATCGTCATCCTGGAAGGCGTGGTGGAAACCACGGGCATCACCACCCAGGCCCGCACCTCCTACCTGGCCGATGAGATCCTGTGGGGCCAGCGCTTTGTGCCCATTGTAGCTGAG------GAGGACGGACGTTACTCTGTGGACTACTCCAAGTTTGGCAACACCATCAAAGTGCCC------......ACACCACTCTGCACGGCCCGCCAGCTTGATGAGGACCACAGC---...---------CTACTGGAAGCTCTGACCCTCGCC------------------------TCAGCCCGCGGGCCCCTG
TRN  10010101100011001
NAM  IRK8_HUMAN/37-380
ASQ  IAKSGACNLAHKNIR-E.QGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYM..............EKSGMEKSglestvCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIES.NNIFLVAPLIICHVIDKRSPLYDISATDLAN.QDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTE--EEGVYSVDYSKFGNTVKVA--..APRCSARELDEKPSI.---LIQTLQKSE-----L-SHQNSL
DSQ  ATCGCCAAGAGCGGGGCCTGCAACCTGGCGCATAAGAACATCCGT---GAG...CAAGGACGCTTTCTACAGGACATCTTCACCACCTTGGTGGACCTGAAATGGCGCCACACGCTGGTCATCTTTACCATGTCCTTCCTCTGCAGCTGGCTGCTCTTCGCTATCATGTGGTGGCTGGTGGCCTTTGCCCATGGGGACATCTATGCTTACATG..........................................GAGAAAAGTGGAATGGAGAAAAGTggtttggagtccactgtgTGTGTGACTAATGTCAGGTCTTTCACTTCTGCTTTTCTCTTCTCCATTGAAGTTCAAGTTACCATTGGGTTTGGAGGGAGGATGATGACAGAGGAATGCCCTTTGGCCATCACGGTTTTGATTCTCCAGAATATTGTGGGTTTGATCATCAATGCAGTCATGTTAGGCTGCATTTTCATGAAAACAGCTCAGGCTCACAGAAGGGCAGAAACTTTGATTTTCAGCCGCCATGCTGTGATTGCCGTCCGAAATGGCAAGCTGTGCTTCATGTTCCGAGTGGGTGACCTGAGGAAAAGCATGATCATTAGTGCCTCTGTGCGCATCCAGGTGGTCAAGAAAACAACTACACCTGAAGGGGAGGTGGTTCCTATTCACCAACTGGACATTCCTGTTGATAACCCAATCGAGAGC...AATAACATTTTTCTGGTGGCCCCTTTGATCATCTGCCACGTGATTGACAAGCGCAGTCCCCTGTATGACATCTCAGCAACTGACCTGGCCAAC...CAAGACTTGGAGGTCATAGTTATTCTGGAAGGAGTGGTTGAAACTACTGGCATCACCACACAAGCACGAACCTCCTACATTGCTGAGGAGATCCAATGGGGCCACCGCTTTGTGTCCATTGTGACTGAG------GAAGAAGGAGTGTATTCTGTGGATTACTCCAAATTTGGCAACACTGTTAAAGTAGCT------......GCTCCACGGTGCAGTGCCCGAGAGCTGGATGAGAAACCTTCCATC...---------CTTATTCAGACCCTCCAAAAGAGTGAA---------------CTG---TCTCATCAAAATTCTCTG
TRN  10010101100011000
NAM  IRK16_RAT/37-358
ASQ  LHKDGSCNVYFKHIFGE.WGSYMVDIFTTLVDTKWRHMFVVFSLSYILSWLIFGSIFWLIALHHGDLLS--..............--DPDITP......CVDNVHSFTAAFLFSLETQTTIGYGYRCVTEECSVAVLTVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYSEDSEG-RMTMAFKDLKLVNDQ--.--IILVTPVTIVHEIDHESPLYALDRKAVAK.DNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFHDVLEV--KRKYYKVNCLQFEGSVEVY--..APFCSAKQLDWKDQ-.-----QLN-----------NLEKTS
DSQ  CTCCACAAAGATGGCAGCTGTAACGTGTACTTTAAACACATTTTTGGAGAA...TGGGGGAGCTACATGGTTGATATATTCACCACTCTTGTGGATACCAAGTGGCGCCATATGTTTGTAGTATTTTCTTTGTCTTACATTCTCTCCTGGTTGATATTCGGCTCCATATTTTGGCTCATAGCCCTTCATCACGGAGACCTATTAAGC------..........................................------GATCCAGACATCACCCCG..................TGCGTGGACAACGTGCATTCATTTACGGCTGCGTTTTTATTCTCCCTTGAGACCCAAACCACCATCGGGTACGGTTACCGTTGTGTCACGGAAGAATGCTCTGTGGCCGTGCTGACGGTCATCCTTCAGTCCATCCTGAGCTGCATCATAAACACCTTCATCATTGGGGCAGCCTTGGCAAAGATGGCGACCGCCCGGAAGCGAGCCCAGACCATCCGCTTCAGCTATTTCGCACTCATCGGCATGAGAGACGGGAAGCTTTGCCTCATGTGGCGCATAGGTGACTTCCGACCGAACCATGTGGTGGAGGGCACGGTGAGAGCCCAACTTCTGCGCTATTCAGAAGACAGCGAAGGG---CGGATGACGATGGCGTTTAAAGACCTCAAACTCGTCAATGACCAG------...------ATAATCCTGGTAACGCCAGTGACCATTGTCCATGAAATTGACCACGAGAGTCCTCTGTATGCCCTTGACCGCAAGGCAGTGGCCAAA...GATAATTTCGAGATTCTGGTGACATTTATTTATACTGGTGACTCTACTGGGACATCCCACCAGTCCAGAAGTTCCTACGTCCCCAGAGAAATTCTCTGGGGACACAGGTTTCATGATGTATTGGAAGTG------AAGAGAAAGTACTACAAGGTAAACTGCTTGCAGTTTGAGGGAAGCGTGGAAGTCTAC------......GCCCCCTTTTGCAGTGCCAAACAACTGGACTGGAAGGACCAA---...---------------CAGCTCAAC---------------------------------AACTTGGAGAAAACGTCC
TRN  10010101100011000
NAM  IRK15_HUMAN/30-365
ASQ  MSKSGHSNVRIDKVDGI.YLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPDE..............-PISNHTP......CIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSS.ESPFLILPMTFYHVLDETSPLRDLTPQNLKE.KEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLS-KNGKYVADFSQFEQIRKSP--..--DCTFYCADSEKQ-.--QLEEKYRQE-------DQREREL
DSQ  ATGTCCAAGAGTGGGCACAGCAACGTGAGAATTGACAAAGTGGATGGCATA...TACCTACTCTACCTGCAAGACCTGTGGACCACAGTTATCGACATGAAGTGGAGATACAAACTCACCCTGTTCGCTGCCACTTTTGTGATGACCTGGTTCCTTTTTGGAGTCATCTACTATGCCATCGCGTTTATTCATGGGGACTTAGAACCCGATGAG..........................................---CCCATTTCAAATCATACCCCC..................TGCATCATGAAAGTGGACTCTCTCACTGGGGCGTTTCTCTTTTCCCTGGAATCCCAGACAACCATTGGCTATGGAGTCCGTTCCATCACAGAGGAATGTCCTCATGCCATCTTCCTGTTGGTTGCTCAGTTGGTCATCACGACCTTGATTGAGATCTTCATCACCGGAACCTTCCTGGCCAAAATCGCCAGACCCAAAAAGCGGGCTGAGACCATCAAGTTCAGCCACTGTGCAGTCATCACCAAGCAGAATGGGAAGCTGTGCTTGGTGATTCAGGTAGCCAATATGAGGAAGAGCCTCTTGATTCAGTGCCAGCTCTCTGGCAAGCTCCTGCAGACCCACGTCACCAAGGAGGGGGAGCGGATTCTCCTCAACCAAGCCACTGTCAAATTCCACGTGGACTCCTCCTCT...GAGAGCCCCTTCCTCATTCTGCCCATGACATTCTACCATGTGCTGGATGAGACGAGCCCCCTGAGAGACCTCACACCCCAAAACCTAAAGGAG...AAGGAGTTTGAGCTTGTGGTCCTCCTCAATGCCACTGTGGAATCCACCAGCGCTGTCTGCCAGAGCCGAACATCTTATATCCCAGAGGAAATCTACTGGGGTTTTGAGTTTGTGCCTGTGGTATCTCTCTCC---AAAAATGGAAAATATGTGGCTGATTTCAGTCAGTTTGAACAGATTCGGAAAAGCCCA------......------GATTGCACATTTTACTGTGCAGATTCTGAGAAACAG---...------CAACTCGAGGAGAAGTACAGGCAGGAG---------------------GATCAGAGGGAAAGAGAACTG
TRN  10010101100011000
NAM  IRK10_HUMAN/31-369
ASQ  LTKDGRSNVRMEHIADK.RFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVWYLVAVAHGDLLELD..............-PPANHTP......CVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTAS.DSPFLILPLTFYHVVDETSPLKDLPLRSG-E.GDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLS-ASGKYIADFSLFDQVVKVASPsgLRDSTVRYGDPEKL-.--KLEESLR---------EQAEKEG
DSQ  CTGACAAAAGATGGTCGCAGCAACGTGAGAATGGAGCACATTGCCGACAAG...CGCTTCCTCTACCTCAAGGACCTGTGGACAACCTTCATTGACATGCAGTGGCGCTACAAGCTTCTGCTCTTCTCTGCGACCTTTGCAGGCACATGGTTCCTCTTTGGCGTGGTGTGGTATCTGGTAGCTGTGGCACATGGGGACCTGCTGGAGCTGGAC..........................................---CCCCCGGCCAACCACACCCCC..................TGTGTGGTACAGGTGCACACACTCACTGGAGCCTTCCTCTTCTCCCTTGAATCCCAAACCACCATTGGCTATGGCTTCCGCTACATCAGTGAGGAATGTCCACTGGCCATTGTGCTTCTTATTGCCCAGCTGGTGCTCACCACCATCCTGGAAATCTTCATCACAGGTACCTTCCTGGCGAAGATTGCCCGGCCCAAGAAGCGGGCTGAGACCATTCGTTTCAGCCAGCATGCAGTTGTGGCCTCCCACAATGGCAAGCCCTGCCTCATGATCCGAGTTGCCAATATGCGCAAAAGCCTCCTCATTGGCTGCCAGGTGACAGGAAAACTGCTTCAGACCCACCAAACCAAGGAAGGGGAGAACATCCGGCTCAACCAGGTCAATGTGACTTTCCAAGTAGACACAGCCTCT...GACAGCCCCTTCCTTATTCTACCCCTTACCTTCTATCATGTGGTAGATGAGACCAGTCCCTTGAAAGATCTCCCTCTTCGCAGTGGT---GAG...GGTGACTTTGAGCTGGTGCTGATCCTAAGTGGGACAGTGGAGTCCACCAGTGCCACCTGTCAGGTGCGCACTTCCTACCTGCCAGAGGAGATCCTTTGGGGCTACGAGTTCACACCTGCCATCTCACTGTCA---GCCAGTGGTAAATACATAGCTGACTTTAGCCTTTTTGACCAAGTTGTGAAAGTGGCCTCTCCTagtggcCTCCGTGACAGCACTGTACGCTACGGAGACCCTGAAAAGCTC---...------AAGTTGGAGGAGTCATTAAGG---------------------------GAGCAAGCTGAGAAGGAGGGC
TRN  10010101100011000
NAM  IRK1_HUMAN/43-380
ASQ  VSKDGRCNIEFGNVEAQsRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFGLLWYAVAYIHKDLPEFH..............-PSANHTP......CVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGN.ENLFFISPLTIYHVIDHNSPFFHMAAETLLQ.QDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKT-KEGKYRVDFHNFSKTVEVETP..---HCAMCLYNEKD-.--VRARMKRGY-------DNPNFIL
DSQ  GTCTCCAAAGATGGAAGGTGCAACATAGAATTTGGCAATGTGGAGGCACAGtcaAGGTTTATATTCTTTGTGGACATCTGGACAACGGTACTTGACCTCAAGTGGAGATACAAAATGACCATTTTCATCACAGCCTTCTTGGGGAGTTGGTTTTTCTTTGGTCTCCTGTGGTATGCAGTAGCGTACATTCACAAAGACCTCCCGGAATTCCAT..........................................---CCTTCTGCCAATCACACTCCC..................TGTGTGGAGAATATTAATGGCTTGACCTCAGCTTTTCTGTTTTCTCTGGAGACTCAAGTGACCATTGGATATGGATTCAGGTGTGTGACAGAACAGTGTGCCACTGCCATTTTTCTGCTTATCTTTCAGTCTATACTTGGAGTTATAATCAATTCTTTCATGTGTGGGGCCATCTTAGCCAAGATCTCCAGGCCCAAAAAACGTGCCAAGACCATTACGTTCAGCAAGAACGCAGTGATCAGCAAACGGGGAGGGAAGCTTTGCCTCCTAATCCGAGTGGCTAATCTCAGGAAGAGCCTTCTTATTGGCAGTCACATTTATGGAAAGCTTCTGAAGACCACAGTCACTCCTGAAGGAGAGACCATTATTTTGGACCAGATCAATATCAACTTTGTAGTTGACGCTGGGAAT...GAAAATTTATTCTTCATCTCCCCATTGACAATTTACCATGTCATTGATCACAACAGCCCTTTCTTCCACATGGCAGCGGAGACCCTTCTCCAG...CAGGACTTTGAATTAGTGGTGTTTTTAGATGGCACAGTGGAGTCCACCAGTGCTACCTGCCAAGTCCGGACATCCTATGTCCCAGAGGAGGTGCTTTGGGGCTACCGTTTTGCTCCCATAGTATCCAAGACA---AAGGAAGGGAAATACCGAGTGGATTTCCATAACTTTAGCAAGACAGTGGAAGTGGAGACCCCT......---------CACTGTGCCATGTGCCTTTATAATGAGAAAGAT---...------GTTAGAGCCAGGATGAAGAGAGGCTAT---------------------GACAACCCCAACTTCATCTTG
TRN  10010101100011000
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