EMBL-EBI > Goldman Group

PANDIT Home | Browse PANDIT | Help on PANDIT | Release notes | Pfam



PANDIT Homepage
pan•dit
PANDIT
Protein and Associated NucleotideDomains with Inferred Trees
(View summary and phylogenies for PF00616 - RasGAP)
FAM  PF00616
PID  RasGAP
DES  GTPase-activator protein for Ras-like GTPase
IPR  IPR001936
ANO  8
ALN  234
AID  0.276677
APH  (((IRA2_YEAST/1722-1891:0.31764,IRA1_YEAST/1730-1899:0.35030):0.54407,(IQGA1_HUMAN/1025-1238:0.80620,GAP1_SCHPO/175-380:0.77242):0.34632):0.15585,((RASA1_BOVIN/766-939:0.61325,GAP1_DROME/525-698:0.59467):0.07342,BUD2_YEAST/541-721:1.09227):0.34487,NF1_HUMAN/1256-1452:0.72301);
ATP  (((IRA2_YEAST/1722-1891,IRA1_YEAST/1730-1899),(IQGA1_HUMAN/1025-1238,GAP1_SCHPO/175-380)),((RASA1_BOVIN/766-939,GAP1_DROME/525-698),BUD2_YEAST/541-721),NF1_HUMAN/1256-1452);
ATL  6.73429
DNO  8
DLN  702
DID  0.410837
DPH  (RASA1_BOVIN/766-939:0.50525,((((GAP1_SCHPO/175-380:0.55984,IQGA1_HUMAN/1025-1238:0.57151):0.15763,NF1_HUMAN/1256-1452:0.57939):0.11445,(IRA1_YEAST/1730-1899:0.25003,IRA2_YEAST/1722-1891:0.29876):0.32688):0.14656,GAP1_DROME/525-698:0.58327):0.03887,BUD2_YEAST/541-721:0.73220);
DTP  (RASA1_BOVIN/766-939,((((GAP1_SCHPO/175-380,IQGA1_HUMAN/1025-1238),NF1_HUMAN/1256-1452),(IRA1_YEAST/1730-1899,IRA2_YEAST/1722-1891)),GAP1_DROME/525-698),BUD2_YEAST/541-721);
DTL  4.8532
RID  0.276677
RPH  (((IRA2_YEAST/1722-1891:0.31764,IRA1_YEAST/1730-1899:0.35030):0.54407,(IQGA1_HUMAN/1025-1238:0.80620,GAP1_SCHPO/175-380:0.77242):0.34632):0.15585,((RASA1_BOVIN/766-939:0.61325,GAP1_DROME/525-698:0.59467):0.07342,BUD2_YEAST/541-721:1.09227):0.34487,NF1_HUMAN/1256-1452:0.72301);
RTP  (((IRA2_YEAST/1722-1891,IRA1_YEAST/1730-1899),(IQGA1_HUMAN/1025-1238,GAP1_SCHPO/175-380)),((RASA1_BOVIN/766-939,GAP1_DROME/525-698),BUD2_YEAST/541-721),NF1_HUMAN/1256-1452);
RTL  6.73429
LNK  BUD2_YEAST/541-721:P33314:X74130
LNK  GAP1_DROME/525-698:P48423:M86655
LNK  GAP1_SCHPO/175-380:P33277:D10457
LNK  IQGA1_HUMAN/1025-1238:P46940:L33075
LNK  IRA1_YEAST/1730-1899:P18963:Z36009
LNK  IRA2_YEAST/1722-1891:P19158:M33779
LNK  NF1_HUMAN/1256-1452:P21359:M89914
LNK  RASA1_BOVIN/766-939:P09851:X12602
AMK  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
DMK  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
NAM  NF1_HUMAN/1256-1452
ASQ  LLWNMFSKEVE-LADSMQTLFRGNSLASKIMTFCFKVY-GATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRL--------------...--------------EPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRI----ERGLKLMSKILQSIANH
DSQ  CTGCTCTGGAACATGTTTTCTAAAGAAGTAGAA---TTGGCAGACTCCATGCAGACTCTCTTCCGAGGCAACAGCTTGGCCAGTAAAATAATGACATTCTGTTTCAAGGTATAT---GGTGCTACCTATCTACAAAAACTCCTGGATCCTTTATTACGAATTGTGATCACATCCTCTGATTGGCAACATGTTAGCTTTGAAGTGGATCCTACCAGGTTA------------------------------------------.........------------------------------------------GAACCATCAGAGAGCCTTGAGGAAAACCAGCGGAACCTCCTTCAGATGACTGAAAAGTTCTTCCATGCCATCATCAGTTCCTCCTCAGAATTCCCCCCTCAACTTCGAAGTGTGTGCCACTGTTTATACCAGGCAACTTGCCACTCCCTACTGAATAAAGCTACAGTAAAAGAAAAAAAGGAAAACAAAAAATCAGTGGTTAGCCAGCGTTTCCCTCAGAACAGCATCGGTGCAGTAGGAAGTGCCATGTTCCTCAGATTTATCAATCCTGCCATTGTCTCACCGTATGAAGCAGGGATTTTAGATAAAAAGCCACCACCTAGAATC------------GAAAGGGGCTTGAAGTTAATGTCAAAGATACTTCAGAGTATTGCCAATCAT
TRN  10010101100011000
NAM  IRA2_YEAST/1722-1891
ASQ  VVAQLIKNEIE-KSSRPTDILRRNSCATRSLSMLARSK-GNEYLIRTLQPLLKKIIQNRD----FFEIEKLKP--------------...--------------EDSDA-ERQIELFVKYMNELLESISNSVSYFPPPLFYICQNIYKVACEKFPDH---------------------AIIAAGSFVFLRFFCPALVSPDSENIIDISHLSE-----KRTFISLAKVIQNIANG
DSQ  GTAGTGGCACAGTTGATTAAAAATGAAATTGAA---AAATCTTCCAGACCTACGGATATCCTTAGAAGAAATAGCTGTGCTACGAGATCATTATCTATGCTAGCCAGGTCCAAG---GGTAACGAATATTTGATTCGCACTTTGCAACCATTACTAAAAAAAATTATCCAGAACAGAGAT------------TTTTTTGAAATTGAGAAACTAAAACCG------------------------------------------.........------------------------------------------GAAGATTCAGATGCT---GAACGTCAAATAGAGCTCTTCGTTAAATACATGAATGAATTATTGGAATCCATATCCAACTCCGTATCTTATTTTCCCCCTCCTTTATTTTATATTTGCCAAAACATTTATAAAGTTGCGTGTGAAAAATTTCCGGATCAC---------------------------------------------------------------GCAATTATCGCCGCTGGGTCTTTCGTGTTTTTACGGTTTTTTTGTCCTGCTTTAGTCAGCCCTGATTCTGAAAATATCATAGATATTTCTCACTTGAGCGAA---------------AAGCGTACCTTCATCAGCTTGGCTAAAGTTATCCAAAATATTGCCAATGGC
TRN  10010101110011000
NAM  IRA1_YEAST/1730-1899
ASQ  LVTELLKQEIK-RAARSDDILRRNSCATRALSLYTRSR-GNKYLIKTLRPVLQGIVDNKE----SFEIDKMK---------------...--------------PGSENSEKMLDLFEKYMTRLIDAITSSIDDFPIELVDICKTIYNAASVNFPEY---------------------AYIAVGSFVFLRFIGPALVSPDSENIII-VTHAHD----RKPFITLAKVIQSLANG
DSQ  CTTGTTACTGAGCTCCTTAAACAAGAAATCAAA---CGGGCCGCAAGATCAGACGATATTCTCAGAAGAAATAGTTGTGCAACAAGGGCTTTGTCACTTTACACTAGATCTAGA---GGTAACAAATATTTGATAAAAACTTTGAGACCCGTTTTGCAAGGGATAGTGGATAACAAGGAG------------TCTTTTGAAATTGATAAGATGAAA---------------------------------------------.........------------------------------------------CCAGGATCCGAAAACTCCGAAAAGATGTTAGACTTATTTGAGAAGTACATGACAAGATTAATTGACGCAATTACAAGTTCTATTGATGATTTCCCAATAGAATTAGTTGATATCTGTAAAACAATTTACAATGCTGCTAGTGTAAATTTTCCAGAATAC---------------------------------------------------------------GCATATATTGCCGTTGGGTCATTCGTTTTCTTGAGGTTTATCGGGCCTGCTTTAGTTAGTCCTGATTCGGAAAATATCATTATT---GTTACGCACGCCCATGAC------------AGAAAGCCCTTTATTACACTAGCTAAAGTTATTCAAAGTTTAGCTAATGGC
TRN  10010101110011000
NAM  RASA1_BOVIN/766-939
ASQ  LLCTLNDREIS-MEDEATTLFRATTLASTLMEQSMKAT-ATQFVHHALKDSILRIMESKQ----SCELSPSKL--------------...--------------EKNEDVNTNLAHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTN------------------TTMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIA----ARTLTLVAKSVQNLAN-
DSQ  TTGTTATGTACACTAAATGACAGAGAAATAAGC---ATGGAAGATGAAGCCACTACCCTCTTTCGAGCCACAACACTTGCGAGCACCTTGATGGAGCAGTCTATGAAAGCCACT---GCTACACAATTTGTTCATCACGCTTTAAAAGACTCTATCTTAAGGATAATGGAAAGCAAGCAG------------TCTTGTGAGTTAAGTCCATCAAAGTTA------------------------------------------.........------------------------------------------GAAAAAAATGAAGATGTGAACACTAATTTAGCACACCTATTGAACATACTTTCAGAGCTTGTGGAGAAAATATTCATGGCTTCAGAAATACTTCCACCGACACTGAGGTATATTTATGGGTGTTTACAGAAATCTGTTCAGCACAAGTGGCCTACAAAT------------------------------------------------------ACCACCATGAGAACAAGAGTTGTTAGTGGTTTTGTTTTTCTTCGACTTATCTGTCCTGCCATCCTGAATCCACGGATGTTTAATATCATCTCAGATTCCCCATCTCCTATTGCT------------GCAAGAACACTGACATTAGTGGCTAAGTCTGTGCAGAACTTAGCAAAT---
TRN  10010101100011000
NAM  GAP1_DROME/525-698
ASQ  IIKALADHEIS-HLTDPTTIFRGNTLVSKMMDEAMRLS-GLHYLHQTLRPVLSQIVAEKK----PCEIDPSKI--------------...--------------KDRSAVDTNLHNLQDYVERVFEAITKSADRCPKVLCQIFHDLRECAGEHFPSN------------------REVRYSVVSGFIFLRFFAPAILGPKLFDLTTERLDAQT----SRTLTLISKTIQSLGN-
DSQ  ATCATCAAGGCGCTGGCTGACCACGAGATCTCC---CATCTGACAGATCCCACCACTATCTTCCGGGGTAACACCTTGGTCTCTAAGATGATGGATGAGGCAATGCGATTGTCT---GGACTGCACTACCTACATCAGACATTGCGTCCGGTTTTGTCGCAGATCGTTGCCGAAAAGAAA------------CCATGTGAGATCGATCCCAGCAAGATT------------------------------------------.........------------------------------------------AAAGATCGCTCTGCGGTGGACACGAATCTGCACAATCTGCAAGATTATGTGGAGCGGGTTTTTGAGGCAATCACCAAGAGCGCTGATCGCTGTCCGAAAGTTCTGTGTCAGATCTTCCACGACCTTCGCGAGTGTGCGGGTGAGCATTTCCCCAGCAAT------------------------------------------------------CGAGAAGTGCGCTACTCCGTGGTGTCCGGCTTTATCTTCCTGCGCTTCTTTGCACCCGCTATCCTGGGACCAAAGCTCTTCGATCTGACCACCGAGCGACTGGATGCCCAAACG------------AGTCGCACGCTGACTCTCATCTCCAAGACGATCCAATCGCTGGGTAAT---
TRN  11011101101011011
NAM  IQGA1_HUMAN/1025-1238
ASQ  LFKTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKS---LNIKTDPVDIYKSWVNQMESQTGEaskLPYDVTPEQALAHEEVKTRLDSSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAG-----------------EDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASN
DSQ  CTCTTTAAGACAGCACTCCAAGAGGAAATCAAGTCGAAGGTAGATCAGATTCAAGAGATTGTGACAGGAAATCCTACGGTTATTAAAATGGTTGTAAGTTTCAACCGTGGTGCCCGTGGCCAGAATGCCCTGAGACAGATCTTGGCCCCAGTCGTGAAGGAAATTATGGATGACAAATCT---------CTCAACATCAAAACTGACCCTGTGGATATTTACAAATCTTGGGTTAATCAGATGGAGTCTCAGACAGGAGAGgcaagcaaaCTGCCCTATGATGTGACCCCTGAGCAGGCGCTAGCTCATGAAGAAGTGAAGACACGGCTAGACAGCTCCATCAGGAACATGCGGGCTGTGACAGACAAGTTTCTCTCAGCCATTGTCAGCTCTGTGGACAAAATCCCTTATGGGATGCGCTTCATTGCCAAAGTGCTGAAGGACTCGTTGCATGAGAAGTTCCCTGATGCTGGT---------------------------------------------------GAGGATGAGCTGCTGAAGATTATTGGTAACTTGCTTTATTATCGATACATGAATCCAGCCATTGTTGCTCCTGATGCCTTTGACATCATTGACCTGTCAGCAGGAGGCCAGCTTACCACAGACCAACGCCGAAATCTGGGCTCCATTGCAAAAATGCTTCAGCATGCTGCTTCCAAT
TRN  10010101100011001
NAM  GAP1_SCHPO/175-380
ASQ  LFQMVLTTEFE-ATSDVLSLLRANTPVSRMLTTYTRRGPGQAYLRSILYQCINDVAIHPD---LQLDIHPLSVYRYLVNTGQLSPSE...DDNLLTNEEVSEFPAVKNAIQERSAQLLLLTKRFLDAVLNSIDEIPYGIRWVCKLIRNLTNRLFPSIS-----------------DSTICSLIGGFFFLRFVNPAIISPQTSMLLDSCPSDNV----RKTLATIAKIIQSVANG
DSQ  CTTTTTCAAATGGTATTAACCACCGAATTTGAG---GCCACTTCTGACGTTTTGTCTCTGCTTAGGGCTAATACTCCGGTATCTAGAATGCTTACAACTTATACACGTCGTGGACCCGGACAAGCATATCTTCGTAGTATCCTTTACCAATGCATTAATGACGTTGCTATCCATCCTGAT---------TTGCAGCTTGACATCCATCCTCTTTCAGTTTATCGCTATTTGGTGAATACCGGTCAATTATCACCATCTGAA.........GATGATAATTTATTAACAAACGAGGAAGTTTCAGAGTTTCCTGCTGTAAAAAATGCAATTCAAGAGCGTTCTGCTCAATTATTGCTTTTGACAAAACGATTTTTAGATGCTGTTCTTAACAGCATCGACGAAATTCCATATGGTATTCGCTGGGTCTGTAAGTTAATTCGCAATCTGACAAATCGTCTGTTTCCTAGTATTTCA---------------------------------------------------GACAGCACTATTTGCTCTTTAATAGGTGGATTTTTCTTTCTTCGTTTCGTTAATCCAGCTATTATTTCGCCACAAACTTCTATGCTTTTAGACAGTTGTCCATCTGATAACGTC------------CGCAAAACACTTGCTACTATTGCAAAAATTATTCAAAGTGTTGCCAATGGC
TRN  10010101100011000
NAM  BUD2_YEAST/541-721
ASQ  TVSRINQKNLD-SKHVFNSLFRGNSILTKSIEQYFFRV-GNEYLSKALSAILKEIIESNK----SCELDPARVKEK-----------...-----------DEVKKRKIIADNYKRLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDT-----------------LQIILNGISGLLFLRFFCPVILNPKLFKYVSQNLNETA----RRNLTLISKVLLNLST-
DSQ  ACGGTTTCAAGAATAAACCAGAAAAATTTAGAC---TCAAAGCATGTTTTCAACAGTTTATTCCGTGGTAACTCTATCTTAACAAAGTCGATTGAACAGTACTTTTTCAGAGTG---GGTAATGAATATTTGAGTAAAGCGCTTAGTGCAATACTAAAAGAGATCATTGAGTCAAACAAA------------TCATGTGAATTGGATCCTGCTAGAGTAAAAGAAAAA---------------------------------.........---------------------------------GATGAAGTAAAAAAGAGGAAAATAATTGCCGACAACTACAAACGATTGTATTCTTGGGTTACGAAGATTTGGAAAAGGCTGTATGCAACGAGTAATGACCTGCCGATTGAAATAAGAAATGTTTTAAAAATCTTTAGGCAAAAACTAGAGATAATTTGTATCGATGACACT---------------------------------------------------TTGCAAATAATTTTGAATGGTATATCAGGATTATTGTTTTTAAGGTTTTTTTGTCCAGTCATATTAAACCCTAAGCTATTCAAATATGTTTCTCAAAATTTAAACGAAACAGCA------------AGAAGGAATCTTACCCTAATAAGTAAAGTTTTACTTAATCTGTCCACT---
TRN  10010101100011000
//