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PANDIT
Protein and Associated NucleotideDomains with Inferred Trees

PF02259 alignment
(33 sequences with 638 aa)


TRA1_DROME/2778-3115 MFLILESSWRVPDWN.LMKIALAKT.EQCYLK------.-------------------...----HYGF----KINLYKGYLSILHQEERQTGNIERYVE-.-.-.IASSLCIREWRRLPN-.IVSHIHLPYLQ.ASQQIMELHE--.---.--.--ASQIHQGLAQS----RNNsLHD....MKAIVKTWRNRLPII-SDDLSHWSDIFTWRQHHYQII....TQHLEQQSD......QGST.M-.---..--.-.-.---.---------------.-----------LGVHASAQAIISFGKIAR---.--.------.KHN----.LTGVCQETLSRIYTIPS--...........---------VPIVDCFQKIRQQVKCYLQmpstsGKNEINEALEVIESTNLKYFTGEMNAEFYALKGLLLAQIG.RSEE--------------------------------------------.------.----AGKSFSVAAQLHDGLTKAWAMWGDYME---QIF..........LKERK--.---------------------------------...............-------ITLAVDALICYLQASRNQ-.....IESKTRKYIAKVLW
TRRAP_HUMAN/2849-3204 PYLVLECAWRVSNWT.AMKEALVQV.EVSC--------.-------------------...------PKEMAWKVNMYRGYLAICHPEEQQLSFIERLVE-.-.-.MASSLAIREWRRLPH-.VVSHVHTPLLQ.AAQQIIELQE--.---.--.--AAQ-INAGLQPTNLGRNNsLHD....MKTVVKTWRNRLPIV-SDDLSHWSSIFMWRQHHYQGK....----PTWSGmhsssiVTAYeNSsQHD.pSS.-.-.---.---------------.-------NNAMLGVHASASAIIQYGKIAR---.--.------.KQG----.LVNVALDILSRIHTIPTVPi.........vDCFQKIRQQVKCYLQLAGVMGKNECM--.....-----QGLEV-IESTNLKYFTKEMTAEFYALKGMFLAQIN.KSEE--------------------------------------------.------.----ANKAFSAAVQMHDVLVKAWAMWGDYLE---NIF..........VKERQ--.---------------------------------...............-------LHLGVSAITCYLHACRHQ-.....NESKSRKYLAKVLW
YAMB_SCHPO/2622-2976 AELYLECAWRLSDW-.--STEQDTL.EKATKS------.-----LSPFTSLRRHTADA...LLYLNKTQ-----------------RKMGSVTEFSRIID-.-.-.ECMQFSLRRWQQLPK-.RVYQSHVSLLH.HFQEIVELQEAFgIYSqLNdTNIHNIDNKLRDI-------.---....-KVVLQGWRERLPNV-WDDIDIWSDLIAWRQSVFKSI....-------NK......VFLPlVS.IAQ.qST.-.-.---.--------------N.KSNTNSVSYLYRGYHELAWIINRFAHVAR---.--.------.VHH----.LPEVCINQLTKIYTLPN--...........---------IEIQEAFLKLREQAECHYE.....SPSEMQLGLEVINNTNLMYFRNRQKAEFFTLKGMFQNRLG.EKDE--------------------------------------------.------.----ANQAFATAVQIDIGSGKAWSEWGLYHDELFQAN..........PQEIH--.---------------------------------...............---------HACNAVSCFLQASSLLS....sSNSKPLLTRVLWLL
Q9HFE8_SCHPO/2682-3036 SELLLECAWRISDWS.NNRESLEVA.IKSL--------.------SDVPTPRKLTFQC...FMTLQKSV-----------------SQPLAIKEFQQVLS-.-.-.EAIQLALIKWHQLPE-.KVNQSHYSLLH.LFQQFVELQE--.---.--.--AATIYSHLNAI----NFQnLPTnvqlIKSALQVWQERLPNV-WDDINLWRDLISWRQIVFSMI....-------NR......VYLPlVP.TI-..-QaNsSaDSSnPPNTSFLF-------.-----------RGYHETAWLINRFAHVAR---.--.------.KHK----.LPSVCLNQLTKIYTLPN--...........---------IEIQEAFYKLREQVLCYLQ.....NPRDLKTGLEVVTNTNLMYFNSRQKSEFVTLKGKFLEKLNrGEE---------------------------------------------.------.----ANQMYAAAVQIDLGLPKAWAEWGRYND------..........-------.------------------------LLFNKSPDN...............L-------SAACNAISCYLQAAGTY-.....QSSKARKMLARVLW
Q9HEI9_NEUCR/2842-3193 QDLLLESIWRNTEYW.QNQENREQL.DNHIKG------.-----LMDAPTPRRSFFQAfmsLLKYHNKQ--------------------ESLQDFNRVVD-.-.-.EAIQLSIRKWHHLPK-.RLTTAHIPILQ.NFQQLVELHDASvICQsLSaTNSNNLDARSGEL-------.---....-KLLLGSWRDRLPNT-WDDIVAWQDLVTWRQHVFGLInntyLQLLPQQGG......QSAGgA-.---..--.-.-.---.---------------.-------SFAYRGFHETAWIINRFAHVAR---.--.------.KHG----.LHEVCINQLSRIYTLPN--...........---------IEIQEAFLKLREQAKCHYQ.....NPEELQNGLEVINNTNLGYFTGQQKAEFFTLKGMFLEKLG.QKDE--------------------------------------------.------.----VDTAYGMALSHDISAPKAWAEWGYFND------..........-------.--------------------RKFRENPAD----...............-------VLAAKQALTCYLQAVSSY-.....KNHKSRKLIARILW
TRA1_YEAST/2756-3108 TDLLLECGWRVADWNsDRDALEQSVkSVMD--------.--------VPTPRRQMFKT...FLALQNFA-----------------ESRKGDQEVRKLCD-.-.-.EGIQLSLIKWVSLPI-.-RYTPAHKWLLhGFQQYMEFLEATqIYAnLHtTTVQNLDSKAQEI-------.---....-KRILQAWRDRLPNT-WDDVNMWNDLVTWRQHAFQVI....---------......----.--.---..--.-.-.---.--NNAYLPLIPALQQsNSNSNINTHAYRGYHEIAWVINRFAHVAR---.--.------.KHN----.MPDVCISQLARIYTLPN--...........---------IEIQEAFLKLREQAKCHYQ.....NMNELTTGLDVISNTNLVYFGTVQKAEFFTLKGMFLSKLR.AYEE--------------------------------------------.------.----ANQAFATAVQIDLNLAKAWAQWGFFND------..........-------.-------------------------------RR...............LSEEPNNISFASNAISCYLQAAGLYK....nSKIRELLCRILWLI
Q8SVL2_ENCCU/2371-2735 YSLSTESLWHLSSFT.DQDALKRFK.SMVD--------.-------------------...---------------------TGKNGFEKEFYDAFASTYAkYsAeKIGKILERNILELRSYpAGSNAGSRFLL.YLQIIIEMIE--.---.--.--AEPIFNDRIDGAESL---.---....-TSILFRWKDKEPSD-QDVFEQWSLFRTWRRHAYSRL....GMIEKTYGG......ETAYkAP.GRS.yAEeMaAsPGRrVPMTSHLFSPKEMIE.GSIKVKKELIAKGTNELAKTLNGFSKAAI---.--.------.EHG----.YYDAALFHLKEVFDLSS--...........---------VKVGDVFQKVVYELLCLLG.....KKEYKIGVEQ-CGSTNIQHFSDSQSSVLFNFRGLFSEKLGkFSD---------------------------------------------.------.----AEKFYLQSVQICNVVGENWLTWAKFLF------..........-------.---------------------------------...............NRINGEGVGPKEDAFVALLQAVVYCN....gKKARKGILKLILLM
Q86C65_DICDI/1392-1718 APLAAAAAWNLVNW-.--DKMDEYV.CAMN--------.--------KDTVEGSFYRA...ILEVHHDN----------------------FTLAHGFID-.-.-.HARTLVDTELTALLG-.ESYNRAYKVVV.RLQQLSELEE--.---.--.--IIEYKKCVDSP----ERR.---....-NMIKNTWKTRLRGC-QHNVDIWQSILAV--------....---------......----.--.---..--.-.-.---.---------------.-------HSLVISPHEELDMWLKFVGLCR---.--.------.KGS----.RLGLAQKTLTMLMGKDPSTt........sqFGSVLPNTHPRITFAYIKQLW----S--.....-----AGAKQ-PAFEKLRTFVQALRDTDDLP---------.-------------------------------LQGRAYLKLGEWQLAL-.GDTLSEaSIPHIISSFKAATECDPNWYKAWHSWALINFEVVSHY..........EQNGG--.---------------------------------...............--TPEQIGAHLLPAVHSFFKSISLGP.....DRSLQDTLRLLTLW
Q9VK45_DROME/1480-1831 GPLAAVAAWGLQDW-.--EAMREYV.RCIP--------.--------EDTQDGSYYRA...VLAVHHDD----------------------FETAQRLID-.-.-.ETRDLLDTELTSMAG-.ESYERAYGAMV.CVQMLAELEE--.---.--.--VIQYKLIPERR-------.---....-EPLKTMWWKRLQGG-QRLVEDWRRIIQV--------....---------......----.--.---..--.-.-.---.---------------.-------HSLVVKPHEDIHTWLKYASLCR---.--.------.KSG----.SLHLSHKTLVMLLGTDPKL..........nPNQPLPCNQPQVTYAYTKYMA----A--.....-----NNQLQ-EAYEQLTHFVSTYSQELSCLPPEALKQQD.QRLM-----------------------------ARCYLRMATWQNKL-.QDSIRPdAIQGALECFEKATSYDPNWYKAWHLWAYMNF------..........-------.-KVVQAQKSALDKQQPPGASMGMTMGSGL----...............DSDLMIIQRYAVPAVQGFFRSISLIK.....GNSLQDTLRLLTLW
Q7Q3H2_ANOGA/1490-1838 GRLAAAAAWGLQDW-.--DGMHRFV.RCIP--------.--------EDTQDGAFYRA...VLAVHNEQ----------------------YALAQSLID-.-.-.STRDLLDTELTAMAG-.ESYERAYGAMV.CVQMLAELEE--.---.--.--VIQYKLIPERR-------.---....-ETIKSMWWDRLLGG-QRLVEDWQRVIQV--------....---------......----.--.---..--.-.-.---.---------------.-------HSLVLSPKEDIRTWLKFASLCR---.--.------.KNG----.SLKLSEKTLTMLLEYDPME..........nLSEPLPIDKPHVTFAYTKHLH----M--.....-----AGYTK-EAYDHLNRFVASFSPQAFTASSGAGGQDD.LKDE------------------------NRRLLARCFLKLGMWQSSSTgGNLVKDhLINGILVCYSRATKHDPNWYKAWHNWAYMNFEVVQAK..........KQQEE--.-------------YTKNPGSAA-----------...............--ERNLIKHYAVPAVRGFFQSINLSQ.....GNSLQDTLRLLTLW
FRAP_HUMAN/1513-1910 ARMAAAAAWGLGQW-.--DSMEEYT.CMIP--------.--------RDTHDGAFYRA...VLALHQDL----------------------FSLAQQCID-.-.-.KARDLLDAELTAMAG-.ESYSRAYGAMV.SCHMLSELEE--.---.--.--VIQYKLVPERR-------.---....-EIIRQIWWERLQGC-QRIVEDWQKILMV--------....---------......----.--.---..--.-.-.---.---------------.-------RSLVVSPHEDMRTWLKYASLCG---.--.------.KSG----.RLALAHKTLVLLLGVDPSR..........qLDHPLPTVHPQVTYAYMKNMW-------.....-----KSARKIDAFQHMQHFVQTMQQQAQH---------AiATEDQQHKQELHK------------------LMARCFLKLGEWQLNLQ.--GINEsTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYkhqnqardekKKLRHASgANITNATTAATTAATATTTASTEGSNSESEAEStensptpsplqkkvtEDLSKTLLMYTVPAVQGFFRSISLSR.....GNNLQDTLRVLTLW
Q7S6V7_NEUCR/1443-1835 APLATTAAWGLGKW-.--DSMDSYL.QSMK--------.--------RFSPDRAFFGA...ILALHRNQ----------------------FREAMACIE-.-.-.QAREGLDTELSALVS-.ESYNRAYQVVV.RVQMLAELEE--.---.--.--LIVYKQCDG------EKQ.---....-ATMRRTWETRLKGC-QRNVEVWQRMLRL--------....---------......----.--.---..--.-.-.---.---------------.-------RSLVMTPQENMHMWTKFANLCR---.--.------.KSG----.RMGLAEKSLKQLIGTDSPLdsvipywhdrhPGSVGNRIASPILYAVLKFQWEIGQSPG.....FRNSEHRVAE-KTLYCLQRFTQETAHRVETSRMHMAAHAQnGMEVQNQPGFAEFNEEMMHPQAQKHWLEQTVLLAKCYLRQGEWMVSLN.KDDWQQrYRAEVLDCYYKATHYNNKWYKAWHAWALANFEVVQYL..........TGNRE--.----------------------------VDVRN...............NGEQNYIIQYVVPAVRGFFESIALSS.....GSSLQDTLRLLALW
TOR1_YEAST/1461-1847 APLAAGAAWGLGEW-.--DMLEQYI.SVMK--------.--------PKSPDKEFFDA...ILYLHKND----------------------YDNASKHIL-.-.-.NARDLLVTEISALIN-.ESYNRAYSVIV.RTQIITEFEE--.---.--.--IIKYKQLPPNS----EKK.---....-LHYQNLWTKRLLGC-QKNVDLWQRVLRV--------....---------......----.--.---..--.-.-.---.---------------.-------RSLVIKPKQDLQIWIKFANLCR---.--.------.KSG----.RMRLANKALNMLLEGGNDP...........SLPNTFKAPPPVVYAQLKYIW----A--.....-----TGAYK-EALNHLIGFTSRLAHDLGLDPNNMIAQSVkLSSASTAPYVEEYTK----------------LLARCFLKQGEWRIAT-.QPNWRNtNPDAILGSYLLATHFDKNWYKAWHNWALANFEVISMV..........QEETKLNgGKNDDDDDTAVNNDNVRIDGSILGSGSLTINGN...............RYPLELIQRHVVPAIKGFFHSISLLE.....TSCLQDTLRLLTLL
TOR2_YEAST/1468-1849 APLAA-AAWGLEQW-.--DEIAQYT.SVMK--------.--------SQSPDKEFYDA...ILCLHRNN----------------------FKKAEVHIF-.-.-.NARDLLVTELSALVN-.ESYNRAYNVVV.RAQIIAELEE--.---.--.--IIKYKKLPQNSDKR----.---....-LTMRETWNTRLLGC-QKNIDVWQRILRV--------....---------......----.--.---..--.-.-.---.---------------.-------RSLVIKPKEDAQVRIKFANLCR---.--.------.KSG----.RMALAKKVLNTLLEETDDP...........DHPNTAKASPPVVYAQLKYLW----A--.....-----TGLQD-EALKQLINFTSRMAHDLGLDPNNMIAQSVpQQSKRVPRHVEDYTK----------------LLARCFLKQGEWRVCL-.QPKWRLsNPDSILGSYLLATHFDNTWYKAWHNWALANFEVISML..........TSVSK--.-KKQEGSDASSVTDINEFDNGMIGVNTFDAKEV...............HYSSNLIHRHVIPAIKGFFHSISLSE.....SSSLQDALRLLTLW
O94188_CRYNE/1384-1737 SPLAAAASWSLKQW-.--DLMDDYI.SAMK--------.--------GDGADRAFFKA...ILAVHRNQ----------------------IPAALKQIS-.-.-.KARERLDPELTTLTG-.DSYGRAYDTVV.RIQMLAELEE--.---.--.--IIAYKDHADEPARQ----.---....-EMQRQTWKKRLAGC-QRDVEVWQRILQV--------....---------......----.--.---..--.-.-.---.---------------.-------RSLVLKPNEDMDTWIEFADLCR---.--.------.TSD----.RLNLAEKTLTSLVGFQYPS...........MEDTRGRAPPPIIFAYLRMAW----AKN.....LQIDSREERY-ETLQHLRDFTDQLTDDVGIGARGPNGRLM.LPDQKLYGSYTK-------------------LLAQCHVELGQWQATL-.RESQGSaDPSGILHDYCLATELDPEWYQAWHTWALANFEVITQL..........EVSQQ--.--------------GLSPVHFT-----------...............--------TYIIPAVEGFLKSISLSP.....GNSLQDTLRLLTLW
TOR1_SCHPO/1360-1709 APLAAAAAWGLGQW-.--NLISEYV.SAMD--------.--------RDPQDKEFFSA...ISAVHLGQ----------------------YNKAYGHIE-.-.-.RHRDILVNDLSSIIG-.ESYNRAYGIMV.KSQMLSELEE--.---.--.--IIDYKKNMQYENNL----.---....-DSLKKTWRKRLEGC-QKNVDVWHNTLRF--------....---------......----.--.---..--.-.-.---.---------------.-------RALVLSPQDSPEMWIKLADLCR---.--.------.RSD----.RLKLSNQCLTYLMGRDPSNa.........yPLDSLKLLNPHVVYTYLKYLW----A--.....-----TDQKN-IAVSELEEFTSYLSSKHGYKMGDSSKLVDiLASSSVSSEERS-------------------FLARCFHKLGKWKKSL-.QDSVNQeSVRDILNCYFYATLFDKSWYKAWHSWALANFEVVGYY..........EQTEH--.---------------------------------...............GVTQDMYEQYIVPAIKGFFHSSVLNQ.....KNSLQDILRLLNLW
Q9FR53_ARATH/1449-1815 APMAAQAAWNMGEW-.--DQMAEYV.SRLDDGDETKLRgLASPVSSGDGSSNGTFFRA...VLLVRRAK----------------------YDEAREYVE-.-.-.RARKCLATELAALVL-.ESYERAYSNMV.RVQQLSELEE--.---.--.--VIEYYTLPVGNTIAEERR.---....-ALIRNMWTQRIQGS-KRNVEVWQALLAV--------....---------......----.--.---..--.-.-.---.---------------.-------RALVLPPTEDVETWLKFASLCR---.--.------.KSG----.RISQAKSTLLKLLPFDPEV..........sPENMQYHGPPQVMLGYLKYQWSLGEE--.....------RKRK-EAFTKLQILTRELSSVPHSQSDILASMVSsKGANVP-------------------------LLARVNLKLGTWQWAL-.SSGLNDgSIQEIRDAFDKSTCYAPKWAKAWHTWALFNTAVMSHY..........ISRGQ--.---------------------------------...............-----IASQYVVSAVTGYFYSIACAAnakgvDDSLQDILRLLTLW
O76222_9TRYP/600-925 ASMGAHAAWLLRRWD.DMEHITSFM.SDED--------.--------YTGTTALFYKA...TLAARKKR----------------------FREAEKLID-.-.-.MCRKRVDSKLSALVA-.ESYDRAYDLFV.GIQQLSELEE--.---.--.--LAMATSDPQSA-------.---....-MHWRQLWERRLSVM---AYEGWPGTLAN--------....---------......----.--.---..--.-.-.---.---------------.-------HTLLVPPSSEIDMWLRFVSLSR---.--.------.AHG----.QGSVSTEVLRELLGNQSIE...........SAIENGIPTPAVAMGSFQHLYETNQRDS.....AIARLQLYVS-KVEGSGAQHVSREREDMAVCHAKLAEWLVhQKKAHRTEDELQK-----------------------------------.------.----IFHHLRRATELDKSNGSIWRTLARVHR------..........-------.-------------------------EAATKPAD...............GSDSSGASGHIMEALSAYLRSVSL--.....SEELEDALGFLSLW
Q9N8R7_9TRYP/1916-2279 AQSGAMAAWILGKWD.DVKMLIERL.PNKE--------.-------KGNITLRHFFQN...ATLFHQEFGCRAQWDCGVQDGQRRLETSPQVEALRASIM-.-.-.RAKMEVDESLKTLLP-.LSYAHAYENLT.MLQHFTEMEE--.---.--.--HIAYMESRTEEFR-----.---....-GQLRERWNRRFAALKPDSLMPNLRSLML--------....---------......----.--.---..--.-.-.---.---------------.-------HSLVLNASEMSVMVVNFCERTGTNYpQLsKWAMEWlKQG----.KFPRANHLSQSCHVLPA--...........---TPVSLEPCVAITYIGQVWSGGQRQK.....AVQLMENFLE-ETHSTLEEQQPAAYGVAQLRLGMWKQEMFaDSFWKVEHRQE-------------------------------------.------.----VLRHFHEAVRAVPGSCEAWHSWGLMNY------..........-------.--------------------------RVQQRDC...............SLSRYEQRLFVEAAHQGFVAAICRSAs...pSTALPGVMRLLQLW
Q7SI27_NEUCR/2135-2473 MPFVLEASWATGRW-.--QIMEKYL.RSYT--------.-------------------...----EGDVTDVFNIGIADALLCLKEGDGERFQELLQAMR-.-.-.---DKVASSMALSAT-.SSFRTCHDVML.KCHVLEDLEM--.---.--.--IANAEPVEGEGH------.---....-APLVKALERRLEVL-GAYVSDKQYVLGVRRAAMEL-....---------......----.--.---..--.-.-.---.---------------.-------MRTKFGDEEISSSWLATARLAR---.--.------.KSG----.STHQSFNAVLRAQQLGD--...........---------SSAVIEYAKLFYKDGQHRK.....AIQLLQRAID-DDLFNDGMMAIDTPT---SSKSQQSHRNLlKARAHLLLAKWLDSTGQTHAGA--------------------------.------.----LRSKFQEAAKTHPQWEKGHYYLGRHYK------..........-------.--------------------KVLESEKALSPDD...............QSDAYLTGETAKLVIENYLRSLNFGT.....KYVHQTLPRILDLW
Q9UV56_EMENI/1565-1906 LPFAVEASWMTGKW-.--EKMHNYL.ELCP--------.-------------------...-----QQATADFNIGIGLALDAFRRGEPQQFREIVDKLR-.-.-.---LSVARSLTANSV-.TSLQSCHDSML.KLHALTEIES--.---.--.--VVLAGGADGSQGSR----.---....-SCLRDALDRRLDVL-GGYISDKQYLLGLRRAAMEL-....---------......----.--.---..--.-.-.---.---------------.--------AGSFADSDIAAAWLTSARLLR---.--.------.RGN----.FGNQAYQSMLNAAHLKD--...........---------RSATIEHARLLWKDGHHRK.....AIQILEGAIA-ANEFAAPALSSNNPNRQYGFSNHEKQQNLlAARAHLLLAKWTDRAGQTQSDI--------------------------.------.----IVQRYREAIKLHNRWEKAHYYLGKHYN------..........-------.--------------------KILDSEKSKPLGK...............EAQIYLSGEASKLVVDNYLRSLAHGN.....KYVFQSLPKVLTLW
RAD3_SCHPO/1519-1846 LNLGIEASWRSLSI-.--DSLKKCL.SKSN--------.-------------------...----------LESFEAKLGSIFYQYLRKDSFAELTERLQ-.-.-.PLYVDAATAIANTGA-.HSAYDCYDILS.KLHAINDFSR--.---.--.--IAETDGIVS---------.---....-DNLDIVLRRRLSQV-APYGKFKHQILSTHLVGYEKF....---------......----.--.---..--.-.-.---.---------------.-----------ENTKKTAEIYLEIARISR---.--.------.KNG----.QFQRAFNAILKAMDLDK--...........---------PLATIEHAQWWWHQGQHRK.....AISELNFSLN-NNMFDLVDEHEERPKNRKETLGNPLKGKVfLKLTKWLGKAGQLGLKD-------------------------------.------.----LETYYHKAVEIYSECENTHYYLGHHRV------..........-------.--------------------LMYEEEQKLPVNE...............QSERFLSGELVTRIINEFGRSLYYGT.....NHIYESMPKLLTLW
Q24135_DROME/1482-1824 AECKSELLWRLGSYD.EMEELQSNW.PAQC--------.-------------------...--------------SQGCLKLRRPLTTRIEFDSLLDGMR-.-.-.ESVLEELRSCSAVQQ-.HSYANAYDAVL.KLHLVHELHC--.---.--.--SQELVEKLEQDRDEDNQEkLM-....-KNYFDDWQYRLQIV-QPQVRIQESIYSFRRNILAEL....QRRLTDRN-......----.--.---..--.-.-.---.---------------.-------HLLPHLKTELARIWLNSAQINR---.--.------.NAG----.QLQRAQLYILKAAEYQP--...........---------SGLFIERAKLLWQKGDQVM.....AMNYLEEQLS-IMRSGCQGNVKQLAAEQRHLFFRGKYLQAvYSAESMHLCADA------------------------------------.------.----VLKYFQEAIAVHRQSESCHVQMAQFLE------..........-------.-----------------------KILEARQGGK...............SEPTGEQDDMLINVMVNYAKSLRYGS.....EHVYQSMPRLISLW
RAD3A_ARATH/1787-2167 CTQGVQAAWRLGKW-.--DLMDEYL.DGAD--------.----------------AEG...LLFSSSDSNASFDRDVAKILHAMMKKDQYSVAEGIAISK-.-.-.---QALIAPLAAAGM-.DSYTRAYPFVV.KLHLLRELED--.---.--.--FQAVLNGDSYLEKSFSTSdQVF....-SKAVDNWENRLRFT-QSSLWTREPLLAFRRLVFGA-....---------......----.--.---..--.-.-.---.---------------.----------SGLGAQVGNCWLQYAKLCR---.--.------.LAG----.HYETAHRAILEAQASGA--...........---------PNVHMEKAKLLWITKRSDS.....AIIELQQSLL-NMPEGVVDSTVISSINSLLMAPPNPEPTVrNTQSFKEKKDVAKTLLLYSKWIHHSGQKQKK-----------------.------.----DVLNLYTQVKELLPWEKGYFHLAKYYD------..........-------.----ELYVDARKCQQESSVFSSAGSKKGSVSSN...............LSTEKAGWDYLFKGMYFYAKALHSGH.....KNLFQALPRLLTLW
Q9DDK7_XENLA/1785-2105 STYRVEAAWKLSQW-.--DLVEEYL.SADR--------.-------------------...-------KSTTWSIRLGQLLLSAKKGERDMFYETLKVVR-.-.-.---AEQIVPLSAASFErGSYQRGYEYIV.RLHMLCELEH--.---.--.-SVKMFLQKPSVEP------.---....-AVDSLNLPARLEMT-QNSYRAREPILAV-RRALQTI....---------......----.--.---..--.-.-.---.---------------.-------NKRPNHADMIGECWLQSARVAR---.--.------.KAG----.HHQTAYNALLNAGESRL--...........---------SELNVERAKWLWSKGDVHQ.....ALIVLQKGAE---LFLSSTSAPPEQQLIHGRAMLLVGRLMeETANFESNA---------------------------------------.------.----VMKKYKDVTALLPEWEDGHFYLAKYYD------..........-------.--------------------------KLMPMVT...............DNKMEKQGDLIRYIVLHFGRSLQFGN.....QYIYQSMPRMLSLW
PRKDC_MOUSE/3024-3472 NSLDLSKMWSEPFY-.-QETYLPYV.IRSKLKLLLQGEgNQSLLTFVDEAMNKELQKT...VLELQYSQELSLLYILQDD-----------IDRATYYIK-.-.-.NGIQIFMQNYSSIDV-.LLYRSRLAKLQ.SVQTLAEIEE--.---.--.--FLSFICKHGDLSSLGPL-.---....-RRLLKTWTSRYPDVVTDPMHIWDDIITNRCFFLSKI....EERLTAPSG......DHSMsVD.EDE.eSI.-.-.---.---------------.-------DREVYEPKEDVRCMLQSCRFTM---.--.------.-------.KMKMIESAW----KQSN--...........---------FSLSMKLLKEMHKESKTRE.....IWRVQWLHSY-SQLNHCRSHTQSPREQVLNTLKTITLLDEsDISNYLNKNIQASCDQSILLGTTCRIMADALSREPACLSDLEENKVNS.------.----ILTLSGSNAENTETVITGLYQRAFHHLSKAVQS..........AEEETQLsCWGHEAAAERAHAYMTLVGFCDQQLRKVEESAS...............QKTSAEMEAYPALVVEKMLRALKLNS.....SEARLKFPRLLQII
Q8WN22_CANFA/3039-3488 NPPDLNKMWSEPFY-.-RETYLPYM.IRSKLKLLLQGEaDQSLLTFIDEAVNKDLQKA...LIELHYSQELSLLYILQDD-----------IDRAKYYIE-.-.-.NCIQIFMQNYSSIDV-.LLHRSRLTKLQ.SVQTMIEIQE--.---.--.--FISFISRQGNLSSQAPL-.---....-KRLLKSWTNRYPDARMDPVHIWDDIITNRCFFLSKI....EEKLTLPLG......DHSLsMDeERD.sSD.-.-.---.---------------.-------KMEVQEQGEEVCSLIKNCMFSM---.--.------.-------.KMKMVESAR----KQHN--...........---------FSLAMKLLKELRRESKTRD.....DWQVKWVHTY-CRLSHSRIQGQSCLQQILSALKTVSLLAGeSTSSYFSKNVLAFHDQNILLGTTYSIIANALRREPACLAEIEESRARR.------.----ILDLSGSSLENAEKVIAVLYQRAFHHLSEAVRT..........AEEEAQPsLRGQGPVASLTDAYMTLADFCDQQLRKEEESAS...............VTESVELQTYPGLVVDNMLKALKLHS.....SEARLKFPRLLQII
Q8WN21_HORSE/3002-3450 NPPDLNKMWNEPFY-.-QETYLPYM.IRSKLKLLLQGEgDQSLLTFIDEAVSKELQKV...LVELHYSQELSLLYILQDD-----------VDRAKYYIE-.-.-.NCIRIFMQSYSSIDV-.LLERSRLTKLQ.SLQALIEIQE--.---.--.--FISFIRKQGNLSSQIPL-.---....-KRLLKTWTNRYPDAKMDPMNIWDDIITNRCFFLSKI....EEKLTIPPD......DHSMnTD.GDEdsSD.-.-.---.---------------.-------RMKVQEQEEDIYSLIKSGKFSM---.--.------.-------.KMKMIESAR----KQKN--...........---------FSLAMKLLKELHKESKTRD.....DWLVKWVQSY-CRLSHSRSQTQNRPEQILTVLKTVSLLDE.NTSSYLSKNIPVSRDHNILLGTTYRIIANALSSDPTCLAEIGESKARR.------.----ILELSGSSLENAEEVIAGLYQRVLHHLSEAVRI..........AEEEAQPfTRGQEPAVGVIDAYMTLVDFCDQQLRKEEESSS...............VTESVQLQMYPALVVDKMLKALRLDS.....NEARLKFPRLLQII
Q8QGX4_CHICK/3029-3478 KPPDLNKTWSDPFY-.-QETYLPYI.IRSKLKLLLNGEnDQTLLTFIDEAMKTEQKKA...LIEMHYSQELSLLYILQDD-----------FDRAKYYIG-.-.-.NGIQIFMQSYSSIDT-.LLYQSRMSKLQ.SVQALTEIQD--.---.--.--FINFMTKTSNIASQAKSL.---....-KRLLRTWTSRYPDAKMDPMNIWDDIITNRCFFLDKL....QEKFLCDKA......NDSMeVD.EES..--.-.-.---.---------------.---SVGDQMEVDQQDEDIHSMIRSCKFNM---.-KlKMIESArKQN----.SFSIAKKLL-----KGL--...........---------RREAKTREDWLV----R--.....-----WNYAY-CRFVHSCSQSQSCPERVLSVLKTISLLED.TKSDYLNKNIMAFRNQNLLLGTTYHIMANALSQDPKCCEQIEEEKTGK.------.----ILELSGESSESPEKILAGLNKRAFQCFSSAARK..........SEEEVQSlSMEHVDVKGVIDAYMTLVGFCDQHLRKEEEGSL...............EINAADLQLFPAIVVEKMIKALKLNS.....REARLRFPRLLQII
Q7RZT9_NEUCR/2008-2399 LDSTFITARRLEIWN.LPAPAATEN.WAVT--------.-------------------...--------------------------VYKAYQSMHQASDInMvRsAVHDGLTKTLKHLTGKsLNTLTLRHQLG.ALATLAELDD--.---.--.--VLNTGDLSEL--------.---....-NGIIEDFQARSKWMMSGQYDDVSRILSCRETTLSLW....---------......----.--.---..SQrHnLrPARlTPANARLAQIRGMLV.SSDIYRFHRATQETLNLSTTLTDLIRPSEQMGlAVdAAIRMEtANSLWDQgEMISSIRMLQNIDKESPL-...........-EKQTVPVSRSDLLSKIGYQVSVARLES.....PDTIQKNYLE-PALKELKGKSEGKEAGR------------.------------------------------------------------.------.----VYHQFAMFCDEQLQNPDGLEDLARLQN-LERGK..........NDEVTQLkALIASTRDSQLKNKYSSHLSKAKQWLDLDQQEL...............RRVEQTRSEFVRLSLQNYLLSLAAS-.....DEYNNDALRFTALW
O74630_SCHPO/1896-2275 SNEVYASAWRMQKWD.IPPLSLDNK.TTKD--------.-------------------...----------------CLVFEVLHAVHNYAIYGNYLHLE-.-.-.EYINKKLLLINPNEE-.PDSLLFYALAY.DLKFLIRCNQ--.---.--.--SQF---------------.---....-NCDILQLLKENKQMSSQLHECFQLLLEIRNVLLSLL....---------......----.--.---..-QsHkQlDLSdDLASFRKYYILELLK.ISESFLIVDNLQNAFSVAMLSDALYRKFDLADeNLkHDIDFLsSKILWQRdEKIDAIGMLSESLSKTN--...........-----SSIFPSISYAYLGNWLYTTKSEK.....TELVSKNYFE-KSLSHMSHLNAKEKAKIYC----------.------------------------------------------------.------.----MFAQFCDNNYSSPDLTEDFKRMEKLYF----EK..........KNDIQQLeRSIVNASNMKEEKMLKNHHSREMSSFIIDEREY...............LRMSTFRSKMLTQSITHYLKCLSES-.....DENDVLISRCCTMW
Q9PTM0_XENLA/622-1018 QEIHFQAAWRNMQWD.DSLPTKNET.SGPG--------.-------------------...--------------YHESLYRAVQSLRDKEFCGFHDHIK-.-.-.YARVKEVEELCSGSL-.ESVYSLYPALC.RLQAIGELAS--.---.--.--VGQMFSRSITDDGL----.---....-KDTFLKWQRQSQLLKDSDFEFLEPVLSLRSVILETL....LQEEKK---......----.--.--Q.pSQ.-.-.---.-------ESLKDILT.KHLLDLSRIARSAGNTQLPEKAMFQIKQYNPSqLGvSEWQLEeAQIFWDKeEPSLAREILKQMINKLEIKsf.......evENDSRLRLLYAESLRLCGKWLAETCLES.....PTVIMQNYLE-KAVEFA-GYSDGAGEKLQEGRMKAFLSLArFSDAQYQRIDNYM-----------------------------------.------.----KSSEFENKQALLRKAKEEVGLIKQHKV------..........-------.-------------QNNRYTVKVERELQLDECAI...............LALREDRKRFLCKAVENYISCLVSG-.....EEHDMWIFRLCSLW
ATM_HUMAN/2096-2491 EELHYQAAWRNMQWD.HCTSVSKEV.EGTS--------.-------------------...--------------YHESLYNALQSLRDREFSTFYESLK-.-.-.YARVKEVEEMCKRSL-.ESVYSLYPTLS.RLQAIGELES--.---.--.--IGELFSRSVTHRQL----.---....-SEVYIKWQKHSQLLKDSDFSFQEPIMALRTVILEIL....---------......----.--.---..--.-.-.-MEkEMDNSQRECIKDILT.KHLVELSILARTFKNTQLPERAIFQIKQYNSVsCGvSEWQLEeAQVFWAKkEQSLALSILKQMIKKLDASc.........aANNPSLKLTYTECLRVCGNWLAETCLEN.....PAVIMQTYLE-KAVEVAGNYDGESSDELRNGKMKAFLSLArFSDTQYQRIENYM-----------------------------------.------.----KSSEFENKQALLKRAKEEVGLLREHKI------..........-------.-------------QTNRYTVKVQRELELDELAL...............RALKEDRKRFLCKAVENYINCLLSG-.....EEHDMWVFRLCSLW