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PANDIT
Protein and Associated NucleotideDomains with Inferred Trees

PF01856 alignment
(29 sequences with 429 aa)


O26053_HELPY/15-211 LFLSVYFLN--.-----PTIMQAKs....rFYVASQYQVGKMIMKK-----------------................---.---.-----.........................--------------.--------.-YNDLKRTIEGASFSLGWEINPTN-......YWFYSRYYFFMDYGNV--.ILNKRT--..........................GAQANMFTYGFGGDLIVEYNKNPLY--................-----VFSLFYGMQVAENTWTISKHS.........-.----ANFIIDDWRSIQGFSLKTSNFRMLGLVGFKFQT--.........------VlFHHDASIEVGIKWPFAF--EYDS------....................---AFVRLFSVFISHTFYL
O25706_HELPY/2-200 HYLRILILS--.--MSFLNILNAEn....lSYMSSSYQIGTVFMR------------------................---.---.-----.........................--------------.--------.-PLNTNKLLQGASILQGYEVNPKND......-WAYSRYYFFIDYGNV--.LFNNDS--..........................TLQANMFTYGVGGDFMVAYAKNPIN--................-----RWAFFFGLQLAANTWILNN--.........-.--KVKDLVVNTWDSLKDFNFHNTYFRAIGKFGVQFR---.........-------.---TIVLYHKVDVEIGMK-IFLTPERRS-....................---LFERSFLFFVSHSWHF
O26031_HELPY/63-388 KNGAFVGISLEvGRADQKTNAYKNgelfqvPFGDVSANDDGKVPDGQTGGCQPASGTPGTPG-................---.---.-----.........................----YTKANCVVNWtSRTMLSTNkNIPGRNQPMYGLGVMTGYKHFIGKK......RWFGLRYYGFFDYGHT--.NFSNSRAAn.................aispfylsDQKADMYTYGFGTDMLFNIIDKPKATAgfflgvnfagntwtnnRVGYFKDGYVYGVNTDADAYMTNADGtitcgdttpAsCNVGINPNSVYTTGKLNAKVNHTIFQFLVNVGIRTNIFEhhgiefgikIPTLPNYfFKGSTTIRAKKQGPLENG-QPTTITGAETnf.................sLTQTLRRQYSMYLRYVYTF
O26005_HELPY/48-248 PLIKFPPYAG-.--AGFEVGYKQFfg....KKKWFGMRYYGFFD-------------------................---.---.-----.........................--------------.--------.-YAHNRFGVMKKGIPVGDSGFIYNS......FSFGGNTLTERDSYQG--.QYYVN---..........................-----LFTYGVGLDTLWNFVNKENM--................-----VFGFVVGIQLAGDSWATSIS-.........-.-----KEIAHYAKHHSNSSYSPANFQFLWKFGVRTHIA-.........-------.--KHNSLELGIKVPTITH-QLFSLTNEKG.y.................tLQADVRRVYAFQISYLRDF
O25945_HELPY/24-242 GNGVFIGAG--.-------YLQGQ......-----AQMHADINSQ------------------................---.---.-----.........................--------------.--------.-KQATSATIKGFDALLGYQFFFG--......KYFGLRLYGFFDYAHANSiRLKNPNYNnevvqlagqvlgkqeinrltsladpkTFEPNMLTYGGAMDVMVNVINNGIM--................-----SLGAFGGVQLAGNSWLMATP-.........-.----SFEGILVEQALVSKKAT--SFQFLFNVGARLRIL-.........-------.--KHSSIEAGVKFPMLKK-NPYITAKNLD....................--IGFRRVYSWYVNYVFTF
O25218_HELPY/21-186 VNGFFMGAG--.-------YQQGR......YGP-YNSNYSDWRHG------------------................---.---.-----.........................--------------.--------.-----NDLY-GLNFKLGFVGFAN--......KWFGARVYGFLDWFNT--.SGTEHT--..........................--KTNLLTYGGGGDLIVNLIPLDKF--................-----ALGLIGGVQLAGNTWMFPY--.........-.------------------DVNQTRFQFLWNLGGRMRVG-.........-------.--DRSAFEAGVKFPMVNQ-GSKD------....................--VGLIRYYSWYVDYVFTF
O25791_HELPY/389-641 SANMTMQNQ--.-KNNWGNGCAGV....eeTLSSLKTSAADFNNQTPQINQAQNLANTL----................---.---.-I---.........................-------QELGNNPfRNMGMIAS.-STTNNGALNGLGVQVGYKQFFGEK......KRWGLRYYGFFDYNHA--.YIKSNF-F..........................NSASDVWTYGVGSDLLFNFINDKNTNF..............lgKNNKISVGFFGGIALAGTSWLNSQ--.........-.-----FVNLKTISNVYSAKVNTANFQFLFNLGLRTNLA-.........RPKKKDShHAAQHGMELGVKIPTINT-NYYSFLDTK-....................--LEYRRLYSVYLNYVFAY
O25086_HELPY/428-745 KDGGTLPNAGV.TSNTWGAGCAYV....geTISALTNSIAHFGTQEQQIQQAENIADTLVNFKsryselgntynsittaLSKvPNA.QSLQNvvskknnpyspqgietnyylnqnsyNQIQTINQELGRNPfRKVGIVN-.-SQTNNGAMNGIGIQVGYKQFFGQK......RKWGARYYGFFDYNHA--.FIKSSF-F..........................NSASDVWTYGFGADALYNFINDKATNF..............lgKNNKLSLGLFGGIALAGTSWLNSE--.........-.-----YVNLATVNNVYNAKMNVANFQFLFNMGVRMNLA-.........RSKKKGSdHAAQHGIELGLKIPTINT-NYYSFMGAE-....................--LKYRRLYSVYLNYVFAY
O24870_HELPY/397-711 GNLRGTPSGTV.TSNTWGAGCAYV....geTVTNLKNSIAHFGDQAERIHNARNLAYTLANFSgqykklgehydsitaaLSSlPDA.QSLQNvvskktnpnspqgiqdnyyidsnihSQVQSRSQELGSNPfRRAGLIAA.-STTNNGAMNGIGFQVGYKQFFGKN......KRWGARYYGFVDYNHT--.YNKSQF-F..........................NSDSDVWTYGVGSDLLVNFINDKAT--................KHNKISFGAFGGIQLAGTSWLNSQ--.........-.-----YVNLANVNNYYKAKINTSNFQFLFNLGLRTNLA-.........RNKRIGAdHSAQHGMELGVKIPTINT-NYYSLLGTT-....................--LQYRRLYSVYLNYVFAY
O25015_HELPY/262-483 NTLQKTPDS--.--KGFQSLVSRS....sySYSLNETQYSEFQT------------TT-----................---.---.-----.........................-------KEFGHNPfRSVGLIN-.-SQSNNGAMNGVGVQLGYKQFFGKN......KFFGIRYYAFFDYNHA--.YIKSNF-F..........................NSASNVFTYGAGSDLLLNFINGGSD--................KNRKVSFGIFGGIALAGTTWLNSQ--.........-.-----FMNLKTTNSAYSAKINNTNFQFLFNTGLRL----.........----QG-.--IHHGVELGVKIPTINT-NYYSFMGAK-....................--LAYRRLYSVYFNYVLAY
O25382_HELPY/46-270 KNAWYLGIS--.--YQVGQASQSVk....nPPKSSEFNYPKFPVG------------------................---.---.-----.........................--------------.--------.-KTDYLAVMQGLGLTVGYKQFFGEK......RWFGARYYGFMDYGHA--.VFGANALTsdnggvc......elhqpcatkvgtmGNLSDMFTYGVGIDTLYNVINKEDA--................-----SFGFFFGAQIAGNSWGNTTG-.........-.----AFLETKSPYKHTSYSLDPAIFQFLFNLGIRTHIG-.........-------.--RHQEFDFGVKIPTINV-YYFNHGNLS-....................--FTYRRQYSLYVGYRYNF
O25410_HELPY/51-273 CTGSVVGCP--.---P-GLTANKHn.....PGGTNINWHAKYAN-------------------................---.---.-----.........................--------------.--------.------GALNGLGLNVGYKKFFQFKsfdmtsKWFGFRVYGLFDYGHA--.TLGKQVYApn........................KIQLDMVSWGVGSDLLADIIDNDNA--................-----SFGIFGGVAIGGNTWKSSAAN.ywkeqiieAkGPDVCTPTYCNPNAPYSTKTSTVAFQVWLNFGVRANIY-.........-------.--KHNGVEFGVRVPLLIN-KFLSAGPNATn...................LYYHLKRDYSLYLGYNYTF
O25772_HELPY/908-1230 NLLGAIPTNGVsDTNNLINLLTEFiktagfIQNNDSSVSTSLTSAFQAITSAISQGFQALQNDispnailtllqeitsnTTTiQSFsQTLRQllgdktffmaqqklidaminarnqvQNAQNQANNYGSQP.VLSQYAAA.-KSTQHGMSNGLGVGLGYKYFFGKA......RKLGLRHYFFFDYGFS--.EIGLAN-Q..........................SVKANIFAYGVGTDFLWNLFRRTYN--................-TKALNFGLFAGVQLGGATWLSSL--.........-.-----RQQIIDNWGSANDIHS-TNFQVALNFGVRTNFAEfk.....rfAKKFHNQgVISQKSVEFGIKVPLINQ-AYLNSAGAD-....................--VSYRRLYTFYINYIMGF
O25036_HELPY/214-431 KDVKTISDR--.-IATYQENLKQLg...gmLKNYDEPYLPQFGP-----------G-------................---.---.-----.........................--------------.--------.-TSSQHGVINGFGIQVGYKQFFGNK......RNIGLRYYAFFDYGFT--.QLGSLS-S..........................AVKANIFTYGAGTDFLWNIFRRVFS--................-DQSLNVGVFGGIQIAGNTWDSSL--.........-.-----RGQIENSFKEYPTPTN---FQFLFNLGLRAHFAStm.......HRRFLSAsQSIQHGMEFGVKIPAINQ-RYLRANGAD-....................--VDYRRLYAFYINYTIGF
O25571_HELPY/299-529 NNANISNSTG-.YQVSYGGHIDQAr..stqLLNNTTNTLAKVTALN-------N---------................---.---.-----.........................--------ELKANP.WLGNFAAG.-NSSQVNAFNGFITKIGYKQFFGEN......KNVGLRYYGFFSYNGA--.GVGNGP-T..........................YNQVNLLTYGVGTDVLYNVFSRSFG--................-SRSLNAGFFGGIQLAGDTYISTL--.........-.-----RNSPQLAN--RPTATK---FQFLFDVGLRMNFG-.........-ILKKDLkSHNQHSIEIGVQIPTIYN-TYYKAGGAE-....................--VKYFRPYSVYWVYGYAF
O25570_HELPY/294-515 NQANAVQGRASqLPNALYNAQVTLd...kiNALNNQVRSMPYLPQFR----------------................---.---.---AG.........................--------------.--------.-NSRSTNILNGFYTKIGYKQFFGKK......RNIGLRYYGFFSYNGA--.SVGFRS-T..........................QNNVGLYTYGVGTDVLYNIFSRSYQ--................-NRSVDMGFFSGIQLAGETFQSTL--.........-.-----RDDPNVKLHGKINNTH---FQFLFDFGMRMNFG-.........-KLDGKSnRHNQHTVEFGVVVPTIYN-TYYKSAGTT-....................--VKYFRPYSVYWSYGYSF
O25771_HELPY/437-696 QTPQLTPQQAQqEQKVIMNQLEQAtn..apTPAQINRILANPYSPTAKTLMAYGLYRSKAVIG................---.---.-----.........................-GVIDEMQTKVNQVyQMGFARNFlEHNSNSNNMNGFGVKMGYKQFFGKK......RMFGLRYYGFYDFGYA--.QFGAES-S..........................LVKATLSSYGAGTDFLYNVFTRKRG--................-TEAIDIGFFAGIQLAGQTWKTNF--.........-.-----LDQVDGNH-LKPKDTS---FQFLFDLGIRTNFS-.........-KIAHQKrSRFSQGIEFGLKIPVLYH-TYYQSEGVT-....................--AKYRRAFSFYVGYNIGF
O25034_HELPY/271-487 GNQLIYKKGLDrTINIINTVLGQFes..saSSLYKISYIPNLFS-------------------................---.---.-----.........................--------------.--------.LKDYQSASMNGFGAKMGYKQFFTHK......KNVGLRYYGFLDYGYA--.NFGDTN-L..........................KVGANLVTYGVGTDFLYNVYERSRR--................-RERTTIGLFFGAQIAGQTWSTNV--.........-.-----TNLLSGQRPDVKSSSF----QFLFDLGVRTNFA-.........--KTNFNkHRLDQGIEFGVKIPVIAH-KYFATQGSS-....................--ASYMRNFSFYVGYSVGF
O25091_HELPY/46-254 VNYQTGSIN--.-LMTNIHEVREVt...n.YQTGYTNIITSVNS-------------------................---.---.-----.........................--------------.--------.VKKLTNMGSNGIGLVMGYNHFFHPD......KILGLRYFAFLDWQGY--.GMRYPKGY..........................YGGNNMITYGVGVDAVWNFFQGSFYQD................-DISVDIGVFGGIAIAGNSWYIGS--.........-.-----KGQELLGITNSSAVDN-TSFQFLFNFGLKALF--.........-------.-VDEHEFEIGFKFPTINN-KYYTTDALK-....................--VQMRRVFAFYVGYNYHF
O24941_HELPY/65-286 CNGNQSGAYG-.-SNTPNMPTASNp...tgGFTHGALGTRGYKG-------------------................---.---.-----.........................--------------.--------.-LSNQQYAINGFGFVVGYKHFFKKS......PQFGMRYYGFFDFASSYYkYYTYNDYG....................mrdarkGSQSFMFGYGAGTDVLFNPAIFNRE--................---NLHFGFFLGVAIGGTSWGPTN--.........-.------YYFKDLADEYRGSFHPSNFQVLVNGGIRLG---.........-------.-TKHQGFEIGLKIQTIRN-NYYTASADNVpeg...............ttYRFTFHRPYAFYWRYIVSF
O25222_HELPY/132-367 EKMQEPITNPLeFEENLRNLEVQFaqsqnrMLSSLSSQIAAISNSLN----------------................---.---.-----.........................--------------.----ALDPnSYSKNISSMYGVSLSVGYKHFFTKK......KNQGLRYYLFYDYGYTNFgFVGNGFDG..........................LGKMNNHLYGLGIDYLYNFIDNAKK--................---HSSVGFYLGFALAGSSWVGSG--.........LsMWVSQTDFINNYLTGYQAKMHTSFFQIPLNFGVRVNVN-.........-------.--RHNGFEMGLKIPLAMN-SFYETHGKGLn...................TSLFFKRLVMFNVSYVYSF
O24908_HELPY/331-595 KAINQVDMALAdLSAADTQKTQAVtlatasDSPTTTTDAINFLNALKSNLMAQKDAFLNVHKN................---.---.-----.........................--------IQTAVAqAQETYTPSvINTNNYGQMYGVDAMAGYKWFFGKT......KRFGFRSYGYYSYNHANLsFVGSQLGImeg.......................ASQVNNFTYGVGFDVLYNFYESKEG--................---YNTAGLFLGFGLGGDSFIVQGES.........-.-YLKSQMHICNNTAGCSASMNTSYFQMPVEFGFRSNFS-.........-------.--KHSGIEVGFKLPLFTN-QFYKERGVDG...................sVDVFYKRNFSIYFNYMINF
O25740_HELPY/55-277 YQLGSIQHN--.--SSNLNLSQQFn....kSQIIFSDSLSPVFK-------------------................---.---.-----.........................--------------.--------.---N-SYVSNGLGVQVGYKWVGKHEet....KWFGFRWGLFYDLSAS--.LYGQKE--..........................SQSVIISTYGTYMDLLLNAYNGDKF--................-----FAGFNLGIAFAGVYDKVSD--.........-.----ALLYQALLLDTFGGKVDPNGFQFLVNLGVRLGN--.........-------.--KHNQFGFGIKIPTYYFNHYYSMNNISNnsedvlkvlrfleyginsllYQVDFRRNYSVYFNYTYIF
O25735_HELPY/47-230 RNTFYLGVG--.------YQLSAIn....tSFSTESVDKSYFMTG------------------................---.---.-----.........................--------------.--------.---------NGFGVVLGGKFVAKTQ....avEHVGFRYGLFYDQT----.-FS-----..........................SHKSYISTYGLEFSGLWDAFNSPKM--................-----FLGLEFGLGIAGATYMPGG--.........-.------AMHGIIAQNLGKENS--LFQLLVKVGFRFG---.........-------.-FLHNEITFGLKFPVIPNKRTEIIDGLS-....................TTTLWHRLPVAYFNYIYNF
O25481_HELPY/58-278 KKPKRKLFN--.--IDKSSHYYGTs....vVQMSWLQSREKFEN-------------------................---.---.-----.........................--------------.--------.HSKYRDIPFAEVSLIYGYKQFFPKK......ERYGFRFYVSLDYAYG--.FFLKNKGVlg....................dslrESSQIPKSYREKLQRKETFINAIFYGAg............adfLYKRAFGTLILGMNFVGETWFYET--.........-.------KIFKKWAKDPLSVYHPYMFQVMLNVGYRYRFS-.........------R.-YKNWAIELGARIPFLTN-DYFKTPLYT-....................--LHFKRNISVYLTSTYDF
O25355_HELPY/87-301 RFAGNGGSG--.----GLFNELSFg....yKYFLGKKRIIGFRH-------------------................---.---.-----.........................--------------.--------.-SLFFGYQLGGVGSVPGSGLIVFLP......YGFNTDLLINWTNDKR--.ASQKYVER........................rvKGLSIFYKDMTGRTLDANTLKKASR--................HVFRKSSGLVIGMELGGSTWFASN--.........-.-------N----LTPFNQVKSRTIFQLQGKFGVRWNNDE.......ydIDRYGDEiYLGGSSVELGVKVPAFKVNYYSDDYGDK-....................--LDYKRVVSVYLNYTYNF
O25992_HELPY/487-746 QNQPAFPSS--.YPNSIYTDCSQVp...agLIGVTSAVWQQLIDQNALPVDYTNLSSQTNY--................LNAsLNT.QDFAT.........................TMLSAISQSLSSTRsSATTYRTSkTSRPFGAPLLGVNLKMGYQKYF--N......DYLGLSSYGIIKYN----.YAQAN---..........................NEKIQQLSYGVGMDVLFDFITNYTNEK..............n.PKNNLTKKVFT--SSLGVFGGLRG--.........-.-----LYNSYYLLNQYKGSGN-LNVTGGLNYRYKHS---.........-KYSVG-.-ISVPLVQLKSRVVSSD--GATTNSITL-....................--NEGGSHFKVFFNYGWIF
O25414_HELPY/402-660 QGQSAFPSN--.YPNSIYHNCADVp...agFLGVTAAVWQQLINQNALPINYANLSTQTNYN-................LNAsLNT.QDLAN.........................SMLSTIQKTFVTS-.SVTNHYSSsASQSFRSPILGVNAKIGYQNYF--N......DFIGLAYYGIIKYN----.YAKAI---..........................NQKVQQLSYGGGIDLLLDFITTYSNKN..............s.PTGIQTKRNFS--SSFGIFGGLRG--.........-.-----LYNSYYVLNKVKGSGN-LDVATGLNYRYKHS---.........-KYSVG-.-ISIPLIQRKASVVSNG--GDYTNSFVF-....................--NEGASHFKVFFNYGWVF
O25137_HELPY/447-700 NHQVYTASN--.YPNSIYTNCAQVp...agLIGVTTAVWQQLINQNALPINFANLNSPTNH--................LNAgLNA.QNFAT.........................SIVSAIAQNFSTT-.STTTYRSS.-SKNFRSPILGVNVKIGYQHYF--N......DYIGLAYYGIIKYN----.YAKTN---..........................DEKIQQLSYGGGMDVLFDFITTYANKK................-QDNPTKKVFA--SSFGVFGGLRG--.........-.-----LYNSYYVFNQVKGSGN-LDIVTGFNYRYKHS---.........-KYSVG-.-ISVPLIQSGIKIASNN--GIYANSVVL-....................--NEGGSHFKVFFNYGWIF