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PANDIT
Protein and Associated NucleotideDomains with Inferred Trees

PF01365 alignment
(18 sequences with 250 aa)


P91905_CAEEL/447-653 EVLKLMEDLIEYFAQPNDEQD---FE...EKQNHLRALRSRQDLFQEEGVLNMILDTIDKFSQMEALPDFAG.-----LIGEETHVKWE................QISTYLYLLVAAMIKGNHYNCAQFASAQR-LDWLFGRLSNPQSAEG--ILDVLYCVLTESPEALNMINEGH-IRSVISLLEKVG.-RDPKVLDVLSSLCEGNGMAVRSSQ--NLIT-QYLLPGK------DLLLQTSMRDHVSSM
RY44_DROME/439-648 EMVMCLEDLINYFSQPEDDME---HE...EKQNRFRALRNRQDLFQEEGVLNLILEAIDKINIITSQGFLAS.----FLAGDETGQSWD................LISTYLYQLLAAIIKGNHTNCAQFANSNR-LNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEH-IKVIISLLEKHG.-RDPKVLDVLCSLCVGNGVAVRSSQ--NNIC-DFLLPGK------NLLLQTLLVDHVASI
Q29621_RABIT/451-655 SVSLSLQDLIGYFHPPDEHLE---HE...DKQNRLRALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFAD.-----VAGREAGESWK................SILNSLYELLAALIRGNRKNCAQFSGSLD---WLISRLERLEASSG--ILEVLHCVLVESPEALNIIKEGH-IKSIISLLDKHG.-RNHKVLDVLCSLCVCHGVAVRSNQ--HLIC-DNLLPGR------DLLLQTRLVNHVSSM
RYR1_PIG/440-644 GVILSLQDLIGYFEPPSEELQ---HE...EKQSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAE.-----FAGEEAAESWK................EIVNLLYEILASLIRGNRANCALFSNNLD---WLVSKLDRLEASSG--ILEVLYCVLIESPEVLNIIQENH-IKSIISLLDKHG.-RNHKVLDVLCSLCVCNGVAVRSNQ--DLIT-ENLLPGR------ELLLQTNLINYVTSI
RYR3_HUMAN/438-642 EVLQTLQDLIAYFQPPEEEMR---HE...DKQNKLRSLKNRQNLFKEEGMLALVLNCIDRLNIYNSVAHFAG.-----IAREESGMAWK................EILNLLYKLLAALIRGNRNNCAQFSNNLD---WLISKLDRLESSSG--ILEVLHCILTESPEALNLIAEGH-IKSIISLLDKHG.-RNHKVLDILCSLCLCNGVAVRANQ--NLIC-DNLLPRR------NLLLQTRLINDVTSI
ITPR3_HUMAN/471-677 FVIQLLEDLVFFVSDVPN---NGQNV...LDIMVTKPNRERQKLMREQNILKQVFGILKAPFREK---GGEGpLVRLEELSDQKNAPYQ................HMFRLCYRVLRHSQEDYRKNQEHIAKQFG--------MMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRK--.NREPRFLDYLSDLCVSNHIAIPVTQ--ELICKCVLDPKN-----SDILIRTELRPVKEMA
ITPR2_HUMAN/471-677 FVTKLLEDLIFFVADVPN---NGQEV...LDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSM-.-LRLEDLGDQRYAPYK................YMLRLCYRVLRHSQQDYRKNQEYIAKNFC--------VMQSQIGYDILAEDTITPLLHNNRKLLEKHITAKEIETFVSLLRR--.NREPRFLDYLSDLCVSNTTAIPVTQ--ELICKFMLSPGN-----ADILIQTKVVSMQADN
ITPR1_MOUSE/472-677 SVTKLLEDLVYFVTGGTNSGQ---DV...LEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDC--GDGPM.-LRLEELGDQRHAPFR................HICRLCYRVLRHSQQDYRKNQEYIAKQFG--------FMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRK--.NREPRFLDYLSDLCVSMNKSIPVTQ--ELICKAVLNPTN-----ADILIETKLVLSRFEF
O77089_PANAR/461-675 SLMLLLLDLLYFTAEKEHEQN--KSEslaLALEVTNPNRDRQKLLREQSILKQIFKILRAPFTETQGGDGP-.LLRIDELNDPRHSAYK................NIFRLCYRLLRLAQQGYRKNQEHIAQHFG--------FMQKQIGIDILAEETITALLHNNRKLLEIHITATEIETFVGLVRKNMhKWDWRFLDYLKVLCISNNQAIPRTQ--ELICKSVFSEKN-----KDILIETRLVEEDIEV
IP3R_DROME/492-704 ALISLLQDIVYFIAGMENEQ-NKTKA...LEFTIKNPIRDRQKLLREQYILKQLFKILQGPFQEHTAGDGPF.-LRLDELSDPKNSPYK................NIFRLCYRILRLSQQDYRKNQEYIAKHFG--------LMQKQIGYDILAEDTITALLHNNRKLLEKHITAAEIETFVGLVRKNMhNWDSRFLDYLSDLCVSNRKAIAVTQ--ELICKSVLSDKN-----KDILIETQVKALRTGS
ITPR3_HUMAN/1171-1345 IVKGILERLNKMCGVGE---------...------QMRKKQQRLLKNMDAHKVMLDLLQIPYDK--------.----------GDAKMM................EILRYTHQFLQKFCAGNPGNQALLHKHLH-----------LFLTPGLLEAETMQHIFLNNYQLCSEISEPV-LQHFVHLLATHG.-RHVQYLDFLHTVIKAEGKYVKKCQ--DMIMTELTNAGD------DVVVFYNDKASLAHL
ITPR2_HUMAN/1181-1355 IVKEILIRLSKLCVQNK---------...------KCRNQHQRLLKNMGAHSVVLDLLQIPYEK--------.----------NDEKMN................EVMNLAHTFLQNFCRGNPQNQVLLHKHLN-----------LFLTPGLLEAETMRHIFMNNYHLCNEISERV-VQHFVHCIETHG.-RHVEYLRFLQTIVKADGKYVKKCQ--DMVMTELINGGE------DVLIFYNDRASFPIL
ITPR1_MOUSE/1175-1354 VVKEILIRLSKLCVQESASVR-----...------KSRKQQQRLLRNMGAHAVVLELLQIPYEKA-------.----------EDTKMQ................EIMRLAHEFLQNFCAGNQQNQALLHKHIN-----------LFLKPGILEAVTMQHIFMNNFQLCSEINERV-VQHFVHCIETHG.-RNVQYIKFLQTIVKAEGKFIKKCQ--DMVMAELVNSGE------DVLVFYNDRASFQTL
O77089_PANAR/1214-1394 RIQQILVRMNKLCVTQSSHGN-----...-----LSPKRNEQRLLRNMGIHSVVLELLQIPYDRK-------.----------EDKRMN................ELIELAHQFLQNFCLGDRANQALLYKSID-----------LFLNPGLLEAKTVCAVFKDNSHLCSEVSERV-IQHFIHCIETHG.-RHVQYLKFLQTIVKAEGQFLRRSQ--DIVMQELVNAGE------DVLVFYNERASFNMF
IP3R_DROME/1275-1456 KVKEILIRMNKFCVTASGPGS-----...----VVKPRKHEQRLLRNVGVHTVVLDLLQNPYDEK-------.----------DDELMK................ELMCLAHEFLQNFCLGNQQNQVLLHNHLD-----------LFLNPGILEAKTVCAIFKDNLALCNEVTDKV-VQHFVHCIEIHG.-RHVAYLQFLQTVVAAENQFIRRCQ--DMVMQELINSGE------DVLVFYNDKGSFNHF
P91905_CAEEL/2240-2464 VYLIQIRELLTVQFEHTEEAILKRGL...WKLMNNRIFFQHPDLMRLLSVHENVMSIMMNILTAQQGTVEHE.-------GDELKEKAPik...........dasEMVVACSRFLCYFCRTSRQNQKAMFEHLSFLLDNATMLLARPSLRGSVPLDVAYSSFMDNNELALALKEEE-LDKVAVYLSRCG.-LQPNSELITKGYPDIGWDPVEGERYIDFLRFCVWINGENVEENANLVIRLLIRRPECLG
RY44_DROME/2224-2453 VGLSQIRALLPVQMSQEEEELMRKRL...WKLVNNATFFQHPDLIRILRVHENVMAVMMNTLGRR-------.------AQAQSDAPTQsevaegapskekdtshEMVVACCRFLCYFCRTGRQNQKAMFDHFDFLLDNANILLARPSLRGSTPLDVAYSSLMENTELALALREHY-LEKIAVYLSRCG.-LQSNSELVEKGYPDLGWDPVEGERYLDFLRYCVWVNGESVEENANLVIRLLIRRPECLG
RYR1_PIG/2158-2366 ECLGQIRSLLIVQMGPQEENLMIQSI...GNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLG---------.------GGESKEIRFP................KMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLG---MQGSTPLDVAAASVIDNNELALALQEQD-LEKVVSYLAGCG.-LQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFG