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pan•dit
PANDIT
Protein and Associated NucleotideDomains with Inferred Trees

PF00632 alignment
(72 sequences with 576 aa)


Q7PY73_ANOGA/920-1227 VLLLEDC-.....QMDAPLF----.-.----.---.-.-.---....-.-YTPGKRGFYSPRQGYPSSER....---MNAFRNVGRLIGLCLLQ.......NELFPLFLQRHVLKFIL-.-.GRQ........................................................-.---IRFH..DLAFFDPVVYES.LRQLIKDSQT--.--.-.-............-.-.-...KtGISILQSLE..INF-VIDLM--.-.VE--.-.-.--.EGSGTVE.-LVPG..GRDIQVNENNVYDY......................VRKYAEY.RM....IKTQEKA.LEAIRSGVFDVLPDTALD.QL....TAEDLRLLLNGVG.....-D.IHVATLISYTAFN....................DESNEPS.EkLtKFKRWLWNVVEK.MSNLERQDLVYFWTGSPALPASEEGFQP-..----MPS.VTIR.........PA............-.---DDSHLPTANTCISRLYIPLYSSKAVLRHKLLLAIK--.TKNFGFV
EDD_HUMAN/2486-2799 SVVDMDLDdtddgDDNAPLF----.-.----.---.-.-.---....-.-YQPGKRGFYTPRPGKNTEAR....---LNCFRNIGRILGLCLLQ.......NELCPITLNRHVIKVLL-.-.GRK........................................................-.---VNWH..DFAFFDPVMYES.LRQLILASQS--.--.-.-............-.-.-...SdADAVFSAMD..LAF-AIDLC--.-.KE--.-.-.--.EGGGQVE.-LIPN..GVNIPVTPQNVYEY......................VRKYAEH.RM....LVVAEQP.LHAMRKGLLDVLPKNSLE.DL....TAEDFRLLVNGCG.....-E.VNVQMLISFTSFN....................DESGENA.EkLlQFKRWFWSIVEK.MSMTERQDLVYFWTSSPSLPASEEGFQP-..----MPS.ITIR.........PP............-.---DDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIK--.TKNFGFV
O17858_CAEEL/2646-2944 VLVGTE--.....SPLDQLF----.-.----.---.-.-.---....-.-EKAPYGEFYVPKIGNGAPMR....---LAAYRTVGRIMGICLSQ.......GDIFPLRFSRHIFSYIL-.-.KLP........................................................-.---ICWL..DLGFYDPVLFNN.LRALFKAHPS--.--.-.-............-.-.-...-.------ELD..TDFSIVEQS--.-.AD--.-.-.--.GKAVTVN.-LKPN..GDEVLVNKDNVIEY......................VYKYAER.VL....VGKRIIT.FEAIREGILDVIPESMLF.GL....TPEDLRLIICGIE.....-S.VSISVLQENTGFL....................DESRASQ.EtLnRFKQWFWQVIES.FTQQEKQELVFFWTGSPALPAAGKWPTS-..-------.ASVM.........LR............-.-PQEDVFLPTANTCISRLYVPVYSSKRVLRTKLLLAIK--.AKNFGFV
Q9SU29_ARATH/560-873 YLVCQEIF.....NPKNTLFLR--.-.----.---.-.-.---....-.-SADDFRRFSPNPASKVDPLH....---PDFFEFTGRVIALALMH.......KVQVGVLFDRVFFLQLA-.-.GLK........................................................-.---ISLE..DIKDTDRIMYNS.CKQILEMDPE--.--.-.-............-.-.-...-.FFDSNAGLG..LTFVLETEEL-.-.----.-.-.--.GKRDTIE.-LCPD..GKLKAVNSKNRKQY......................VDLLIER.RF....ATPILEQ.VKQFSRGFTDMLSHSVPPrSFfkrlYLEDLDGMLRGGE.....-NpISIDDWKAHTEYN....................-GFKETD.R.-.-QIDWFWKILKK.MTEEEQRSILFFWTSNKFVPVEGFRGLS-..-----SK.LYIY.........RL............-.-YEANDRLPLSHTCFYRLCIPRYPTITLMEQRLRLIAQDHvSSSFGKW
Q9VQ67_DROME/657-971 ELVCSALF.....DARGGLFCT--.-.----.---.-.-.---....-.-FHDKHQALVHPNPTRPAHLK....---LKHFEFAGKMVGKCLFEsalggtyRQLVRARFSRSFLAQLI-.-.GLR........................................................-.---VHYK..YFEQDDPDLYLSkIKYILDTDLD--.--.-.-............-.-.-...-.---ATDTLE..LYFVEEMYDSSsGqL---.-.-.--.--SKTIE.-LIPN..GAKTRVTNATKNQY......................LDALAQQ.RL....CNNVKDE.VDSFLKGLNSIIPDNLLS.IF....DENELELLMCGTG.....-E.YSISDFKAHHIAN....................GNSAEFR.R.-.-VLAWFWAGVSN.FSQTEMARLLQFTTGCSQLPPGGFQELN-..-----PQ.FQIT.........AA............-.--PTFGNLPTAHTCFNQLCLPDYESYEQFEKSLLLAISEG.SEGFGMV
O15033_HUMAN/515-826 ELICKALF.....DTTNQLFTR--.-.----.---.-.-.---....-.-FSDNNQALVHPNPNRPAHLR....---LKMYEFAGRLVGKCLYEsslggayKQLVRARFTRSFLAQII-.-.GLR........................................................-.---MHYK..YFETDDPEFYKSkVCFILNNDMS--.--.-.-............-.-.-...-.------EME..LVF-AEEKYNKsGqL---.-.-.--.--DKVVE.-LMTG..GAQTPVTNANKIFY......................LNLLAQY.RL....ASQVKEE.VEHFLKGLNELVPENLLA.IF....DENELELLMCGTG.....-D.ISVSDFKAHAVVV....................GGSWHFR.E.-.KVMRWFWTVVSS.LTQEELARLLQFTTGSSQLPPGGFAALC-..-----PS.FQII.........AA............-.--PTHSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEG.CEGFGML
Q8SR14_ENCCU/2104-2410 VLLAKDLL.....DPNFALFEFA-.-.----.---.-.-.---....-.-TEDKTTVVPCKNSYV-NPEH....---LSYFKFVGRIIAKAIMD.......GNFINLHLSKFIYQYIL-.-.GKS........................................................-.---CDLQ..DLESADPEFHKS.LVWIRDNPVD--.--.-.-............-.-.-...-.-----KSLG..ITFSFDDVS--.-.F---.-.-.--.GVHRTVE.-LVEG..GAHVFVDDSNKAEY......................VKLATQY.RL....FNGIELQ.LSALKSGLFEILGSKALE.MF....DESELELLICGIP.....-D.IDVDDWKNNTLYY....................-GYAENS.K.-.-TVIWFWRAVKS.LDSVSRAKLLQFVTGTSTLPFEGFSHLQ-..GNNEVQK.FSIH.........KV............-.-SDRIDSLPTAHTCFNQLVLPEYSSYENLLKYLTLAINEC.STGFGFI
Q8IYU2_HUMAN/602-909 DILSNEIV.....NPDYALFTQ--.-.----.---.-.-.---....-.-SADGTTFQPNSNSYV-NPDH....---LNYFRFAGQILGLALNH.......RQLVNIYFTRSFYKHIL-.-.GIP........................................................-.---VNYQ..DVASIDPEYAKN.LQWILDNDIS--.--.-.-............-.-.-...-.---DLG-LE..LTFSVETDV--.-.F---.-.-.--.GAMEEVP.-LKPG..GGSILVTQNNKAEY......................VQLVTEL.RM....TRAIQPQ.INAFLQGFHMFIPPSLIQ.LF....DEYELELLLSGMP.....-E.IDVSDWIKNTEYT....................SGYERED.P.-.-VIQWFWEVVED.ITQEERVLLLQFVTGSSRVPHGGFANIM-..GGSGLQN.FTIA.........AV............-.-PYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCG.SYGYTMA
Q8IB94_PLAF7/8285-8591 SILAKEIF.....NPNYALFCRE-.-.----.---.-.-.---....-.-GKKSEFNHPNPLSYI-NPDH....---LHFFKFVGKFIAKAIYD.......GQVIDAYFCRSFYKHML-.-.GRK........................................................-.---ILPA..DAESVDPEFYNS.LIKISEYKLE--.--.-.-............-.-.-...-.---DLN-LE..INFSTEIDE--.-.F---.-.-.--.GKTKVID.-LIPN..GRNIPVTDENKHKY......................IELLCEL.KV....TNSIKEQ.LEAFMDGFKELIQPKLIS.IF....DDKELELLISGIP.....-T.IDLNDLKENVEYH....................-NYTANS.I.-.-QIIWLWDVLQE.FDENKKASFLQFVTGTSRVPLGGFKNLM-..GMRGAQK.MIIY.........KA............-.--YGEDRLPTAHTCFNQLDLPEYSSKELLKSKLIRAIMEG.KEGFGFI
Q9GUP2_CAEEL/3870-4177 SVITREIF.....NPNYALFITA-.-.----.---.-.-.---....-.-PGDMVTYMINKASYI-NPEH....---LDYFKFVGRLIAKSVFE.......HKYLDCYFTRAFYKHIL-.-.NLP........................................................-.---VRYQ..DLESEDPAFFKS.LDFLLQNPID--.--.-.-............-.-.-...-.---DLA-LD..LTFSTEVEE--.-.F---.-.-.--.GVRSVRD.-LKPN..GRKIEVNDANKDEY......................VKLVCQM.KM....TGSIRKQ.LDAFLTGFYEIIPKDLIS.MF....NEQELELLISGLP.....-T.VDIDDMAANTDYK....................-GFQKTS.T.-.-HIQWFWRALRS.FEKEDKAKFLQFVTGTSKVPLQGFASLE-..GMNGVQK.FSIH.........MD............-.-SRGGDRLPAAHTCFNQLDLPQYESYEKLRQSLLLAIREC.TEGFGFA
UREB1_HUMAN/3053-3360 MIISREMF.....NPMYALFRTS-.-.----.---.-.-.---....-.-PGDRVTYTINPSSH-CNPNH....---LSYFKFVGRIVAKAVYD.......NRLLECYFTRSFYKHIL-.-.GKS........................................................-.---VRYT..DMESEDYHFYQG.LVYLLENDVS--.--.-.-............-.-.-...-.------TLGydLTFSTEVQE--.-.F---.-.-.--.GVCEVRD.-LKPN..GANILVTEENKKEY......................VHLVCQM.RM....TGAIRKQ.LAAFLEGFYEIIPKRLIS.IF....TEQELELLISGLP.....-T.IDIDDLKSNTEYH....................-KYQSNS.I.-.-QIQWFWRALRS.FDQADRAKFLQFVTGTSKVPLQGFAALE-..GMNGIQK.FQIH.........RD............-.-DRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC.SEGFGLA
TOM1_YEAST/2962-3268 QVLSRQMF.....NPDYALFLPV-.-.----.---.-.-.---....-.-PSDKTTFHPNRTSGI-NPEH....---LSFFKFIGMIIGKAIRD.......QCFLDCHFSREVYKNIL-.-.GRP........................................................-.---VSLK..DMESLDPDYYKS.LVWILENDIT--.--.-.-............-.-.-...-.-----DIIE..ETFSVETDD--.-.Y---.-.-.--.GEHKVIN.-LIEG..GKDIIVTEANKQDY......................VKKVVEY.KL....QTSVKEQ.MDNFLVGFYALISKDLIT.IF....DEQELELLISGLP.....-D.IDVDDWKNNTTYV....................-NYTATC.K.-.-EVSYFWRAVRS.FDAEERAKLLQFVTGTSKVPLNGFKELS-..GVNGVCK.FSIH.........RD............-.-FGSSERLPSSHTCFNQLNLPPYESYETLRGSLLLAINEG.HEGFGLA
TOM1_NEUCR/3759-4065 QVLSRQMF.....DPNYVLFVPV-.-.----.---.-.-.---....-.-SSDRTTFHPNKLSPI-NDEH....---LPFFKFIGRIIGKALYE.......GRLLECYFSRAVYKRIL-.-.GKP........................................................-.---VSVK..DMESFDPDYYKS.LVWMLENDIT--.--.-.-............-.-.-...-.-----DIIT..ETFSVEDDV--.-.F---.-.-.--.GEVKVVD.-LIEN..GRNIPVTEENKHEY......................VRLIVEH.KL....ITSVKDQ.MKAFLTGFHEIIPEELIA.IF....NEQELELLISGLP.....-D.IDIDDWKANTEYH....................-NYSAGA.P.-.-QIQWFWRAVRS.FDKEELAKLLQFVTGTSKVPLNGFKELE-..GMNGVSR.FNIH.........RD............-.-YGSKDRLPSSHTCFNQLDLPEYENYETLRSQLLKAITAG.SDYFGFA
PTR1_SCHPO/2921-3227 QVLARQMF.....NPDYALFLPV-.-.----.---.-.-.---....-.-TGDATTFHPNRDSSV-NPDH....---LSFFKFTGRIIGKALYD.......GRLLDCHFSRAVYKHML-.-.HRS........................................................-.---VSVK..DIESLDPDYYKS.LVWMLNNDIT--.--.-.-............-.-.-...-.-----DIIT..EEFAVEKDV--.-.F---.-.-.--.GEKTVVD.-LIPN..GRNIPVTELNKQNY......................VNRMVDY.KL....RESVKDQ.LKSLLDGFSDIIPSHLIQ.IF....NEQELELLISGLP.....-E.IDIDDWKNNTEYH....................-GYNVSS.P.-.-QVQWFWRAVRS.FDEEERAKLLQFATGTSKVPLNGFKELE-..GMSGFQR.FNIH.........KS............-.-YGSLNRLPQSHTCFNQLDLPEYDTYEQLRSMLLTAINEG.SEGFGFA
UPL2_ARATH/3346-3658 QLLSRVIF.....DKGALLFTT--.-.----.---.-.-.---....-.-VGNDATFQPNPNSVY-QTEH....---LSYFKFVGRMVAKALFD.......GQLLDVYFTRSFYKHIL-.-.GVK........................................................-.---VTYH..DIEAVDPDYYKN.LKWLLENDVS--.--.-.-............-.-.-...-.-----DILD..LTFSMDADEEKhIlY---.-.-.--.EKTEVTDyELKPG..GRNIRVTEETKHEY......................VDLVADH.IL....TSAIRPQ.INAFLEGLNELIPRELVS.IF....NDKELELLISGLP.....-E.IDFDDLKANTEYT....................-SYTVGS.P.-.-VIRWFWEVVKA.FSKEDMARFLQFVTGTSKVPLEGFKALQ-..GISGPQR.LQIH.........KA............-.-YGSPERLPSAHTCFNQLDLPEYQSKEQVQERLLLAIHEA.NEGFGFA
Q8K4P8_MOUSE/1278-1583 FLLSQELF.....NPYYGLFEYS-.-.----.---.-.-.---....-.-ANDTYTVQISPMSAF-VENY....---LEWFRFSGRILGLALIH.......QYLPDAFFTRPFYKGLL-.-.KLP........................................................-.---CDLS..DLEYLDEEFHQS.LQWMKDNNIT--.--.-.-............-.-.-...-.-----DILD..LTFTVNEEV--.-.F---.-.-.--.GQVTERE.-LKSG..GANTQVTEKNKKEY......................IERMVKW.RV....ERGVVQQ.TEALLRGFYEVVDSRLVS.VF....DARELELVIAGTA.....-E.IDLNDWRNNTEYR....................GGYHDGH.L.-.-VIRWFWAAVER.FNNEQRLRLLQFVTGTSSMPYEGFAALR-..GSNGLRR.FCIE.........KW............-.--GKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAV-EE.TSTFGLE
Q9W325_DROME/130-437 FLLSRELF.....NPYYGLFEYS-.-.----.---.-.-.---....-.-ANDTYTVQVSPLSAF-VDNC....---HDWFRFSGRVLGLALVH.......QYLLDAFFTRPFYKALL-.-.RLP........................................................-.---VALS..DLESLDNEFHQS.LQWIRDNDIG--.--.-.-............-.-.-...-.-----TGVDlgLTFCVTEEL--.-.L---.-.-.--.GSVVDRE.-LKPG..GKNIIINEKNKKEY......................LERMIKW.RL....ERGVQEQ.TESLVRGFYEVIDSRLVS.VF....DARELELVIAGTA.....-E.IDTNDWRLNTEYR....................SGYHDNH.Q.-.-VIVWFWQVIER.FSNEQRLRLLQFVTGTSSIPYEGFSALR-..GSTGPRR.FCIE.........KW............-.--GKPNALPRAHTCFNRLDLPPYPTPELLYEKLLLAV-EE.TNTFGIE
Q7QE66_ANOGA/128-437 YLLSRQLF.....SPYRNMFEYS-.-.----.---.-.-.---....-.-ANDIYTVQIAPERPTDRDDI....---LEWYRFAGRVLGLALVH.......QYLLDAFFTRPFYKALL-.-.RLP........................................................-.---VSLS..DLESLDSSFHQS.LLWIRDNNMD--.--.-.-............-.-.-...-.---NCGELG..LNFTVTEERS-.-.D---.-.-.--.GTSIDIE.-LKPN..GRNITVSERNKRDY......................LDRIIKW.RL....ERGVLEQ.TEWLVRGFNEVVDHRLVA.VF....DASELELVISGTV.....-E.IDVHDWRANTEYR....................GGYHDTH.H.-.-VIMWFWAVIER.MSNEQRLRLLQFVTGTSSIPHDGFAGLR-..GSNGLRR.FCIE.........KW............-.--GKANALPRSHTCFNRLDLPPYPTPDVLYEKLVLAV-EE.TNTFGIE
PUB1_SCHPO/463-767 FLLSHEMF.....NPFYCLFEYS-.-.----.---.-.-.---....-.-SVDNYTLQINPHSGI-NPEH....---LNYFKFIGRVIGLAIFH.......RRFVDAFFVVSFYKMIL-.-.QKK........................................................-.---VTLQ..DMESMDAEYYRS.LVWILDNDIT--.--.-.-............-.-.-...-.-----GVLD..LTFSVEDNC--.-.F---.-.-.--.GEVVTID.-LKPN..GRNIEVTEENKREY......................VDLVTVW.RI....QKRIEEQ.FNAFHEGFSELIPQELIN.VF....DERELELLIGGIS.....-E.IDMEDWKKHTDYR....................-SYSEND.Q.-.-IIKWFWELMDE.WSNEKKSRLLQFTTGTSRIPVNGFKDLQ-..GSDGPRK.FTIE.........KA............-.--GEPNKLPKAHTCFNRLDLPPYTSKKDLDHKLSIAV-EE.TIGFGQE
Q7RV01_NEUCR/502-806 FLLSHEMF.....NPFYCLFEYS-.-.----.---.-.-.---....-.-AHDNYTLQINPHSGI-NPEH....---LNYFKFIGRVVGLAIFH.......RRFLDAFFIGALYKMVL-.-.GKA........................................................-.---VSLA..DMEGVDADFHRS.LQWMLDNDIT--.--.-.-............-.-.-...-.-----DVLD..ATFSTEDER--.-.F---.-.-.--.GVITEED.-LIPN..GRNIAVTNENKKEY......................VELMVKW.RI....EKRIEQQ.FRAFKDGFHELIPQDLIN.VF....DERELELLIGGIA.....-E.IDVDDWKKHTDYR....................-GYTESD.E.-.-VIQFFWQTVRS.WDGEQKSRLLQFTTGTSRIPVNGFKDLQ-..GSDGPRR.FTIE.........KA............-.--GEITNLPKAHTCFNRLDLPPYKSLEMLQQKLTIAV-EE.TMGFGQE
RSP5_YEAST/505-809 FLLSHEMF.....NPFYCLFEYS-.-.----.---.-.-.---....-.-AYDNYTIQINPNSGI-NPEH....---LNYFKFIGRVVGLGVFH.......RRFLDAFFVGALYKMML-.-.RKK........................................................-.---VVLQ..DMEGVDAEVYNS.LNWMLENSID--.--.-.-............-.-.-...-.-----GVLD..LTFSADDER--.-.F---.-.-.--.GEVVTVD.-LKPD..GRNIEVTDGNKKEY......................VELYTQW.RI....VDRVQEQ.FKAFMDGFNELIPEDLVT.VF....DERELELLIGGIA.....-E.IDIEDWKKHTDYR....................-GYQESD.E.-.-VIQWFWKCVSE.WDNEQRARLLQFTTGTSRIPVNGFKDLQ-..GSDGPRR.FTIE.........KA............-.--GEVQQLPKSHTCFNRVDLPQYVDYDSMKQKLTLAV-EE.TIGFGQE
PUB3_SCHPO/482-786 FLLSHKMF.....DPIYCLFEYS-.-.----.---.-.-.---....-.-AVDNYTLQINPHSSI-NPEH....---LNYFRFIGRVIGLAIFH.......RRFLDAFFVVSLYKKLL-.-.RKK........................................................-.---VSLA..DMESIDAEFYRS.LKWVLENDIT--.--.-.-............-.-.-...-.-----GILD..LTFSVEEDH--.-.F---.-.-.--.GEVRTVE.-LITN..GENIEVTEENKKKY......................VDLVTEW.RV....SKRVEQQ.FNAFYSGFVELVSPDLVN.VF....DERELELLIGGIS.....-D.VDVEDWKSHTEYR....................-TYIATD.P.-.-VIKWFWEIIAG.WKNEDRSKLLQFATGTSRIPVNGFRDLQ-..GSDGPRK.FTIE.........KA............-.--GTPDQLPVAHTCFNRLDLPDYPSKDTLHEKLSLAV-EN.TVGFGNE
Q9BKW4_CAEEL/441-723 FLLSHQIF.....NPYYGLFEYS-.-.----.---.-.-.---....-.-ATDNYTLQINPHSEACNPEH....---LSYFHFIGRIIGMAIYH.......GKLLDAFFIRPFYKMML-.-.GKK........................................................-.---ITLF..DMESVDNEYYNS.LIYVKDNDPA--.--.-.-............-.-.-...-.------DLE..LTFSLDDSI--.-.F---.-.-.--.GETQNIE.-LIPN..GANVPVTEDNKEEY......................IE-----.--....-------.---------AVVPSNLLR.LF....DANELELLMCGLQ.....-K.IDVKDWKANTIYK....................GGYGPSS.Q.-.-VVHNFWKCILS.FDNEMRARVLQFVSGTSRVPMNGFRELY-..GSNGLQK.FTIE.........RW............-.--GSADMLPRAHTCFNRLDLPPYTTFKELKSKLLTAI-EN.SEIFSGV
O42573_XENLA/665-970 FLLSKEMF.....NPYYGLFEYS-.-.----.---.-.-.---....-.-ATDNYTLQINPNSGLCNEDH....---LSYFTFIGRIAGLAVFH.......GKLLDGFFIRPFYKMML-.-.GKQ........................................................-.---ITLK..DMESVDSEYYNS.LKWILENDPT--.--.-.-............-.-.-...-.------ELD..LMFCIDEEN--.-.F---.-.-.--.GQTYQVD.-LKPN..GSEMVVTNDNKREY......................IDLVIQW.RF....VNRVQKQ.MNAFLEGFTELIAIDLIK.IF....DENELELLMCGLG.....-D.VDVNDWRQHTLYK....................NGYCPNH.P.-.-AVQWFWKAVLL.MDAEKRIRLLQFVTGTSRVPMNGFAELY-..GSNGPQL.FTIE.........QW............-.--GSPDKLPRAHTCFNRLDLPPYDSFEDLREKLLMAV-EN.AQGFEGV
Q9VVI3_DROME/701-1006 YLLSKEMF.....NPYYGLFEYS-.-.----.---.-.-.---....-.-AMDNYTLQINNGSGLCNEEH....---LSYFKFIGRIAGMAVYH.......GKLLDAFFIRPFYKMML-.-.QKP........................................................-.---IDLK..DMESVDTEYYNS.LMWIKENDPR--.--.-.-............-.-.-...-.------ILE..LTFCLDEDV--.-.F---.-.-.--.GQKSQHE.-LKPG..GANIDVTNENKDEY......................IKLVIEW.RF....VARVKEQ.MSSFLDGFGSIIPLNLIK.IF....DEHELELLMCGIQ.....-N.IDVKDWRENTLYK....................GDYHMNH.I.-.-IIQWFWRAVLS.FSNEMRSRLLQFVTGTSRVPMNGFKELY-..GSNGPQM.FTIE.........KW............-.--GTPNNFPRAHTCFNRLDLPPYEGYLQLKDKLIKAI-EG.SQGFAGV
Q95XU3_CAEEL/487-792 FLLSHEVL.....NPMYCLFMYA-.-.----.---.-.-.---....-.-GNNNYSLQINPASFV-NPDH....---LKYFEYIGRFIAMALFH.......GKFIYSGFTMPFYKKML-.-.NKK........................................................-.---IVLK..DIEQVDSEIYNS.LMWIKDNNID--.--.-.-............-.-.-...-.----ECDME..LYFVADYEL--.-.L---.-.-.--.GELKTYE.-LKEG..GTEIAVTEENKLEY......................IELLVEW.RF....NRGVEQQ.TKAFFTGFNSVFPLEWMQ.YF....DERELELLLCGMQ.....-D.VDVDDWQRNTVYR....................-HYAPQS.K.-.-QVTWFWQWVRS.LDQEKRARLLQFVTGTCRVPVGGFSELM-..GSTGPQL.FCIE.........RV............-.--GKENWLPRSHTCFNRLDLPPYRSYDQLVEKLSMAI-EM.TEGFGNE
Q9Y0H4_DROME/644-949 FLLSHEVL.....NPMYCLFEYA-.-.----.---.-.-.---....-.-NKNNYSLQINPASYV-NPDH....---LQYFKFIGRFIAMALYH.......GRFIYSGFTMPFYKRML-.-.NKK........................................................-.---LTIK..DIETIDPEFYNS.LIWVKDNNID--.--.-.-............-.-.-...-.----ECGLE..LWFSVDFEV--.-.L---.-.-.--.GQIIHHE.-LKEN..GEKERVTEENKEEY......................ITLMTEW.RM....TRGIEQQ.TKTFLEGFNEVVPLEWLK.YF....DERELELILCGMQ.....-D.VDVEDWQRNTIYR....................-HYNRNS.K.-.-QVVWFWQFVRE.TDNEKRARLLQFVTGTCRVPVGGFAELM-..GSNGPQR.FCIE.........KV............-.--GKETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAI-EE.TEGFCQE
ITCH_HUMAN/598-903 FLLSHEVL.....NPMYCLFEYA-.-.----.---.-.-.---....-.-GKDNYCLQINPASYI-NPDH....---LKYFRFIGRFIAMALFH.......GKFIDTGFSLPFYKRIL-.-.NKP........................................................-.---VGLK..DLESIDPEFYNS.LIWVKENNIE--.--.-.-............-.-.-...-.----ECDLE..MYFSVDKEI--.-.L---.-.-.--.GEIKSHD.-LKPN..GGNILVTEENKEEY......................IRMVAEW.RL....SRGVEEQ.TQAFFEGFNEILPQQYLQ.YF....DAKELEVLLCGMQ.....-E.IDLNDWQRHAIYR....................-HYARTS.K.-.-QIMWFWQFVKE.IDNEKRMRLLQFVTGTCRLPVGGFADLM-..GSNGPQK.FCIE.........KV............-.--GKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAI-EE.TEGFGQE
WWP2_HUMAN/565-870 FLLSHEVL.....NPMYCLFEYA-.-.----.---.-.-.---....-.-GKNNYCLQINPASSI-NPDH....---LTYFRFIGRFIAMALYH.......GKFIDTGFTLPFYKRML-.-.NKR........................................................-.---PTLK..DLESIDPEFYNS.IVWIKENNLE--.--.-.-............-.-.-...-.----ECGLE..LYFIQDMEI--.-.L---.-.-.--.GKVTTHE.-LKEG..GESIRVTEENKEEY......................IMLLTDW.RF....TRGVEEQ.TKAFLDGFNEVAPLEWLR.YF....DEKELELMLCGMQ.....-E.IDMSDWQKSTIYR....................-HYTKNS.K.-.-QIQWFWQVVKE.MDNEKRIRLLQFVTGTCRLPVGGFAELI-..GSNGPQK.FCID.........KV............-.--GKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAI-EE.TEGFGQE
Q8K300_MOUSE/423-728 YLLCHEML.....NPYYGLFQYS-.-.----.---.-.-.---....-.-TDNIYTLQINPDSSI-NPDH....---LSYFHFVGRIMGLAVFH.......GHYINGGFTVPFYKQLL-.-.GKP........................................................-.---IQLS..DLESVDPELHKS.LVWILENDIT--.--.-.-............-.-.-...-.-----PVLD..HTFCVEHNA--.-.F---.-.-.--.GRILQHE.-LKPN..GRNVPVTEENKKEY......................VRLYVNW.RF....MRGIEAQ.FLALQKGFNELIPQHLLK.PF....DQKELELIIGGLD.....-K.IDLNDWKSNTRLK....................-HCVADS.N.-.-IVRWFWQAVET.FDEERRARLLQFVTGSTRVPLQGFKALQ-..GAAGPRL.FTIH.........LI............-.-DANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAV-EE.TCGFAVE
Q7PSQ3_ANOGA/730-1039 YLLSHEML.....NPQYGLFQYS-.-.----.---.-.-.---....-.-RDDHYSLQINPDSSI-NPEH....---LSYFHFVGRILGIAVFH.......NHVLDGGFTLPFYKQLL-.-.NKP........................................................-.---ITLS..DIEDVDPDLHRS.LTWILENNIT--.--.-.-............-.-.-...-.-----GIID..STFSVENNS--.-.F---.-.-.--.GVLKVHE.-LKPN..GASIAVTEDNKREY......................VKLYVNY.RF....MRGIEQQ.FLALSKGFGELILSHLLR.PF....DERELELLISGIS.....-K.IDVNDWKANTRLK....................-QCTADT.P.-.-QIVWFWQIVES.YSPEMRAQLLQFVTGSCRVPLQGFRALQGstGAVGPRL.FTIH.........LT............-.ADVPLQNLPKAHTCFNRLDLPMYDSYQLMYDKLTQAV-EE.TCGFAVE
PUB2_SCHPO/367-671 YILSHAIF.....NPGYSLFEYA-.-.----.---.-.-.---....-.-TDDNYGLQISPLSSV-NPDF....---RSYFRFVGRVMGLAIYH.......RRYLDVQFVLPFYKRIL-.-.QKP........................................................-.---LCLE..DVKDVDEVYYES.LKWIKNNDVD--.--.-.-............-.-.-...-.-----ESLC..LNFSVEENR--.-.F---.-.-.--.GESVTVD.-LIPN..GRNIAVNNQNKMNY......................LKALTEH.KL....VTSTEEQ.FNALKGGLNELIPDSVLQ.IF....NENELDTLLNGKR.....-D.IDVQDWKRFTDYR....................-SYTETD.D.-.-IVIWFWELLSE.WSPEKKAKLLQFATGTSRLPLSGFKDMH-..GSDGPRK.FTIE.........KV............-.--GHISQLPKAHTCFNRLDIPPYNSKEELEQKLTIAI-QE.TAGFGTE
Q09547_CAEEL/571-889 ILLSRELF.....HPKNGYFEY--.-.----.---.-.-.---....-.-EGNDYHLQLRPRGCETEKEK....----KWLILCGRVLALAVIH.......RCYIDVFFTNVFYKSLQ-.-.KRP........................................................-.---VTLM..DFKESDAEFYKS.MNWLLENDVV--.--.-.-............-.-.-...-.------DLEmsFVYSSMVNG--.-.KVSDlTlSsIVsVALQLAEqELVPG..GESQMVTEANKAEF......................IDLMCQK.KA....IRGVEKP.LEILLTSFNQILNDNLLN.SL....ESSDLKRILSGSL.....-E.LDLNDWRTNTIYK....................GGYSDCH.I.-.-VVEWFWEVIET.MTNQERFDLLLFVTGSSSVPFEGFSALR-..GNEEISK.FCIE.........KW............-.--GDATSFPRAHTCFNRLQLPSYNTKQQLKSKLQQAI-VN.GMSYSIE
Q7RCE4_PLAYO/2-312 TLCVYENK.....NPDFLNLSQ--.-.----.---.-.-.---....-.-YNEIKNYFINLTKN------....---SENYDNINNVLINTI-D.......QNISTISRNEVYLNSIPFrGsRSS........................................................-.-------..GSINENQNMLQN.NTLISSISGG--.--.-.-............-.-.-...-.-------YIntMANRVGEADEAkEvDEADeAkEvDEvDEFDCID.-LIPN..GRNINVNNENKELY......................IKLYIDY.KY....NKLIQKK.TQHFLKGLSQLIPVKWLK.LF....SAHELKILISGND.....-KcFDVNDLRNNVTYS....................GGYNENS.K.-.-TIINLFEILNN.FTPNEKSLFLIFVTSCSRSPLLGFKELY-..-----PK.FCIA.........RV............-.--PDNTRLPTSSTCVNLLKLPDYETKEILYQNLITAI-NG.TQGFDLS
Q8IIH3_PLAF7/1839-2147 STFSHNNM.....NRNNFINIPNGiNnININnIIMnDdTsNYS....-.-STDERSAHIPPTDLEYSFSH....-RDFIPFHELGEQ------N.......EHMEEELPSINIRRKNMEnNdDKK........................................................-.-------..NKRNNKHNIYNNkNNNITNNNLC--.--.-.-............-.-.-...-.---------..-----------.-.----.-.-.DDeQNWECID.-LIEN..GRNIPVTDKNKKLY......................IKLYINY.KY....NQLIKKK.TQRFSKGLSQLIPIKWFK.LF....SAHELKTLISGKD.....-KcFDVDDLKRNVVYG....................GGYNENS.T.-.-TVLHLFEILKD.FSSNEKSLFLMFVTSCSRSPLLGFQELY-..-----PK.FCIY.........RV............-.--PDHTRLPTASTCVNLLKLPDYLSKEVLYKNLITAI-ND.TQGFDLS
HUL5_YEAST/607-910 TTVSDEGF....kDPKHELFR---.-.----.---.-.-.---....-.-TNDRYELYPSVVYDATK---....---LKYIWFLGKVVGKCLYE.......HVLIDVSFADFFLKKLLNySnGFL........................................................-.---SSFS..DLGSYDSVLYNN.LIKLLNMTTD--.--.-.-............-.-.-...-.---EIKSLD..LTFEIDEPE--.-.----.-.-.--.SSAKVVD.-LIPN..GSKTYVTKDNVLLY......................VTKVTDY.KL....NKRCFKP.VSAFHGGLSVIIAPHWME.MF....NSIELQMLISGER.....-DnIDLDDLKSNTEYG....................-GYKEED.Q.-.-TIVDFWEVLNE.FKFEEKLNFLKFVTSVPQAPLQGFKALD-..-----PK.FGIR.........NA............-.-GTEKYRLPTASTCVNLLKLPDYRNKTILREKLLYAI-NS.GARFDLS
Q9SCQ2_ARATH/828-1142 TDITKAAF.....ATEYGLFSQ--.-.----.---.-.-.---....-.-TPTSDRLLVPSPSARHLENG....---IQMIEFLGRIVGKALYE.......GILLDYSFSHVFIQKLL-.-.GRY........................................................-.---SFID..ELSGLDPELYRN.LMYVKHYDGD--.--.-.-............-.-.-...-.----LKELC..LDFTVTEEFC-.-.----.-.-.--.GKMSIIE.-LKPG..GKDTSVTNENKMQY......................IHAMADY.KL....NRQIVPF.SNAFYRGLTDLISPAWLK.LF....NAHEFNQLLSGGN.....-HdIDVDDLRRNTKYT....................GGYSDSS.R.-.-TIKIFWEVMKG.FEPSERCLLLKFVTSCSRAPLLGFKYLQ-..-----PT.FIIH.........KVscdt....slwaAiGGQDVERLPSASTCYNTLKLPTYKRASTMREKLLYAI-TS.NAGFELS
Q9AUK0_ORYSA/437-751 TDLSKAAF.....SPEYGLFSQ--.-.----.---.-.-.---....-.-ASASDSSLIPSNSAKLLDNG....---IDMIEFLGRVVGKALYE.......GILLDYCFSPVFVQKLL-.-.GRY........................................................-.---SFLD..ELSTLDSELYRS.LMQLKHYEGD--.--.-.-............-.-.-...-.----VEDLC..LDFTLTEELG-.-.----.-.-.--.GRRIVHE.-LRPG..GKNISVTNENKLHY......................VHAIADY.KL....NRQILPF.ANAFYRGLGDLISPSWLS.LF....NANEFNQLLSGGL.....-QdFDVDDLRNNTKYT....................GGYTESS.R.-.-SVKLFWEVIKG.FKPTERCMLLKFVTSCSRAPLLGFKYLQ-..-----PS.FTIH.........KVpcdv....tlwaTiGGQDVDRLPSASTCYNTLKLPTYKRSSTLRSKLLYAI-SS.NTGFELS
Q9W196_DROME/819-1122 SELIKTAF.....DPNRGFFM---.-.----.---.-.-.---....-.-VTTDNKLYPNPNVADLFEDY....---EKHYYFIGRILGKSIYE.......NLLVELPLAEFFLTKLA-.-.GKY........................................................-.---SDVDihQLASLDPELYRN.LLYLKDYSGD--.--.-.-............-.-.-...-.----VSELN..LDFTVASSS--.-.L---.-.-.--.GQTQIVE.-LKPQ..GQSIPVTNSNRIEY......................LQLIADY.KL....NVQIRRH.CNAFRKGLSNVLPIEWLY.MF....SNKELQILISGAE.....-IpIDLEDLKKHCEYG....................GEFSPEH.P.-.-SIVTFWEVLEG.FDDMQRRQLLKFVTSCSRPPLLGFKDLD-..-----PP.FFIQ.........NT............-.--GDMERLPTASTCTNLLKLPPFKTVEQMREKLLYAI-QS.GAGFELS
Q7Q342_ANOGA/783-1086 SELIKLAF.....DPHRGFFM---.-.----.---.-.-.---....-.-ITKDNMLYPNPCVGKIVEDF....---QRHYYFIGRILGKALYE.......NLLVELPLAEFFLSKLA-.-.GKH........................................................-.-SDVDVH..QLASLDPVLYRN.LMSLKAYEGD--.--.-.-............-.-.-...-.----VADLG..LDFTIVCDA--.-.L---.-.-.--.GETKVEE.-LKPN..GTNIIVNSTNRIEY......................IQLMADF.KL....NQQIRAQ.CAAFRQGLANVLPIEWLY.MF....SNKELQVLISGAE.....-IpVDVHDLRQHTRYG....................GDFSLEH.H.-.-TIQLFWKVVEQ.FDDIQRRLLLKFVTSCSRPPLLGFKDLD-..-----PP.FYIQ.........NA............-.--GDTDRLPSASTCMNLLKLPAFEEEDVLREKLLYAI-QS.GAGFELS
O15979_CAEEL/326-655 ELTLKKVF.....DPQLNLFS---.-.----.---.-.-.---....-.-TTSTGVLYPSPTSSLHDDH-....---LALFTFVGRMLGKAVYE.......GIVVDVQLAPVLLAAVL-.-.GSH........................................................-.-RLCAFD..ELSQLDPELYRS.LTFVKRYEGE--.--.-.-............-.-.-...-.----MADLS..LTFSVDEDF--.-.M---.-.-.--.GKISTVD.-LVPS..GRTISVTNENKIDY......................VHRMAHH.RV....FRRTQEQ.CKAFVTGMQSILQPTWLS.LF....APNDLQCLISGVN.....--.SDIDPGGSECAMC....................-NISEDS.MeTiGLLNGFGIFLRTsSTSEERKLFLKFVTSCSRPPVLGFSYLE-..-----PP.FSIRcvevsddqdQGdtlgsvvrgflaLrKGTAATRLPTASTCFNLLKLPNYNKKSLLLEKLRYAI-HA.GTGFELS
Q7QUF0_GIALA/647-961 NLICDEMF.....SKALDLFEE--.-.----.---.-.-.---....-.-NQETHSFYFNRKNGTVAEGSe.qwIKLSKNYCFAGMILGMCLLN.......RVNITNHFPRVLYRKLL-.-.GYK........................................................-.---GVFE..DLENYDLTIYKG.LCNLYNYAAQ--.--.-.-............-.-.LregSnLPSIKDTFC..LTFTA------.-.----.-.-.--.LGPNGEDvPLIEG..GQEIYVDEHNVEGY......................IKAYANY.IL....NDSVSRQ.FEDFADGFHLLVRSRSLT.LF....TPADLEIALCGEP.....-N.LDFIALKNNTKYD....................EPLSPTH.P.-.-LIIWFWDIVLNvMTQDQRKALLKFVCGSARAPVGGLSRLR-..-------.FKIT.........LN............-.-GDNDQFLPTSHTCFGILMLPNYSLKEILQERLFKAI-QY.DEGFGLK
Q9BL11_CAEEL/717-1019 ILVMRKIL.....QSDYGMFSE--.-.----.---.-.-.---....-.-DEESHLVWFSGLPSEFCD--....---REQFHQLGRLVGLSIYN.......HSIVPFPFPLALYKYLL-.-.DTP........................................................-.---PDLE..DLCELSPSEGKG.LKMLLSYEED--.--.-.-............-.-.-...-.--DVEDVFG..LNFCISFNI--.-.L---.-.-.--.GETHTTE.-LLSG..GTEKPVTNANRDEY......................VRLYVHH.RLelgyNGEIAQQ.ALLFRKGFSESLHSRTLR.FF....QPCELKEMIVGNE.....-N.YDWNEFRDILMYR....................GEYSSSH.P.-.-TIQAFWKAFFA.LTDDERRKFLQFLTGSTRIPVSGWEELH-..-------.AAIQ.........--............-.-PSAPESLPVAHTCFNLLDLPNIADDVELLRRLRISI-EH.TEGFTLA
Q8IXP9_HUMAN/751-1049 LLIMRELL.....DPKYGMFRY--.-.----.---.-.-.---....-.-YEDSRLIWFSDKTFED----....---SDLFHLIGVICGLAIYN.......CTIVDLHFPLALYKKLL-.-.KKK........................................................-.---PSLD..DLKELMPDVGRS.MQQLLDYPED--.--.-.-............-.-.-...-.--DIEETFC..LNFTITVEN--.-.F---.-.-.--.GATEVKE.-LVLN..GADTAVNKQNRQEF......................VDAYVDY.IF....NKSVASL.FDAFHAGFHKVCGGKVLL.LF....QPNELQAMVIGNT.....-N.YDWKELEKNTEYK....................GEYWAEH.P.-.-TIKIFWEVFHE.LPLEKKKQFLLFLTGSDRIPILGMKSLK-..-------.LVIQ.........ST............-.-GGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAI-DH.NEGFSLI
Q8CFQ0_MOUSE/752-1050 LLLLKELL.....NPIYGMFTY--.-.----.---.-.-.---....-.-YQDSNLLWFSDTCFVE----....---HNWFHLIGITCGLAIYN.......STVVDLHFPLALYKKLL-.-.NVK........................................................-.---PSLE..DLKELSPTEGRS.LQELLDYPGE--.--.-.-............-.-.-...-.--DIEETFC..LNFTVCRES--.-.Y---.-.-.--.GVIEQKK.-LIPG..GDRVAVCKDNRQEF......................VDAYVNY.IF....QISVHEW.YTAFSSGFLKVCGGKVLE.LF....QPAELRAMMVGNS.....-N.YDWEELEETAVYR....................GDYSSTH.P.-.-TVKLFWETFHE.FPLEKKKKFLLFLTGSDRIPIYGMASLQ-..-------.IIIQ.........ST............-.-ATGEEYLPVAHTCYNLLDLPKYSSKEIMKARLTQAL-DN.YEGFSLA
Q9W0H2_DROME/761-1058 MLLLKDLL.....DPKYGMFKE--.-.----.---.-.-.---....-.-YEQSRLLWFADLTFET----....---ENMYFLIGVLCGLAIYN.......FTIINLPFPLALFKKLL-.-.GKP........................................................-.---VDLS..DLRQLSPPEANS.MQSLLDYQGD--.--.-.-............-.-.-...-.--DFKEVFD..LTFEISRDV--.-.F---.-.-.--.GEAETKC.-LKPN..GNEIAVTLENRQEF......................VDLYVDF.VF....NKSVELH.YNAFHKGFMKVCSGRVIH.IF....QPEELMAVVVGNE.....-D.YDWQALQDNCEYR....................EGYTSVD.D.-.-TIKWFWEVIHD.MSEAEKKSFLLFLTGSDRIPIQGMKALK-..-------.LTIQ.........PT............-.--PDERFLPVAHTCFNLLDLPRYKTKERLKYKLLQAI-QQ.TQGFSLV
Q7PT00_ANOGA/682-980 MLLLRDIL.....DPKYGMFKS--.-.----.---.-.-.---....-.-FEESNAIWFTEDYFDSDDSM....------FALIGILCGLAIYN.......FTIIALPFPLALYKKLL-.-.GEE........................................................-.---VDMK..DLRDLAPTVARS.MQSILDYEGG--.--.-.-............-.-.-...-.--DLEEVFD..LCFTTTRDY--.-.F---.-.-.--.GEVQTIP.-LKPN..GENIRLTQGNKQEF......................VNLYIDY.VF....NKAVEKS.FRQFHAGFMRVCGGRVMK.LF....KAHELMSVVVGNE.....-E.YDWNVLEENAEYK....................NGYTCGD.Q.-.-TIRWFWEVFHE.LPLEEKKKFLLFLTGCDRIPIMGMKAIK-..-------.IFIQ.........PT............-.--PDDKFLPVAHTCFNLLDLPQYQTKEKLKYKLLQAI-QQ.TQGFSLV
Q8CDU6_MOUSE/464-774 LLLIRQIF.....HPDYGMFTY--.-.----.---.-.-.---....-.-HKDSHCHWFSSFKCDN----....---YSEFRLVGILMGLAVYN.......SITLDIRFPPCCYKKLL-.-.SPPvvps...............................................dqstpVgICSVTID..DLCQVMPELAHG.LKELLSYEGN--.--.-.-............-.-.-...-.---VEEDFY..STFQVFQEE--.-.F---.-.-.--.GVIKSYN.-LKPG..GDKIPVTNQNRREY......................VQLYTDF.LL....NKSIYKQ.FAAFYCGFHSVCASNALM.LL....RPEEVEILVCGSP.....-E.LDMHALQRSTQYD....................-GYAKTD.L.-.-TIRYFWDVVLG.FPLELQKKLLHFTTGSDRVPVGGMADLN-..-------.FKIS.........KN............-.-ETSTNWLPVAHTCFNQLCLPPYKSRKDLKQKLIIGI-SN.SEGFGLE
Q7YYE6_CRYPV/485-785 QLLVQEIF.....NIDFGMFIY--.-.----.---.-.-.---....-.-YEDTRLFWFNMASLES----....---NGEFELIGIVLALAIYN.......GIILDVHFPLAVYKKLL-.-.GYK........................................................-.---VDIG..DLYEIQPEVANS.LLSLLSIKSD--.--.-.-............-.-.-...-.--SEMEQLC..LTFSATINN--.-.F---.-.-.--.GVMAEVP.-IAPGefDPSEPVTICNVHRY......................VELYLDW.FL....NKSIESQ.FRAFYNGFQSVCGGRTLE.LF....SPEELVLVICGSS.....-D.FNIDSLIEASQYQ....................DGYTKDS.T.-.-TVVMFWEIVKK.LDLKLQKKLLFFVTGSDRVPMKGLGELG-..-------.FVIG.........RH............-.-GPDSDLLPTAHTCFNFLLIPDYQNKEKLERLLLIAL-EH.SKGFGLK
Q9VTH1_DROME/673-973 QLIVEEIF.....NPAFGMFIQ--.-.----.---.-.-.---....-.-QEETNNMWFNATPFEN----....---GAQFTLIGIIIGLAIYN.......NVTLAVNFPMVVYRKLI-.-.GYC........................................................-.---GTFA..DLSDWSPALYKS.LKSMLDYQGQ--.--.-.-............-.-.-...-.--DMEEVFE..QTFKISYSD--.-.V---.-.-.-F.GDVVQHE.-LVPN..GQDVLVGQHNKELF......................VNLYSDF.LL....NTNIEQQ.FNAFRKGFEMVTDESPLKlLF....RPEEIEMLVCGSR.....-E.FDFVELENSTVYE....................GGYTEKS.Q.-.-YIQDFWSIVHA.MPSEDKHKLLEFTTGSARVPVGGLKCLR-..-------.LLIT.........RH............-.-GPDSDRLPTSHTCFNVLLLPEYSSREKLEERLMKAI-NY.SKGFGML
Q9XZN5_MYAAR/576-876 QLIVEEIF.....NVDFGMFTY--.-.----.---.-.-.---....-.-NPDTRQFWFNPMSFEN----....---EGQFTLCGIVLGLAIYN.......STIVDVHFPSVVYRKLV-.-.GKL........................................................-.---GTFQ..DLKGVDPTLART.LQDLLDYEGT--.--.-.-............-.-.-...-.--DMEDVFM..QTFQISYLD--.-.V---.-.-.-F.GSTITHS.-LKDA..GETIPVNQLNKQEF......................VDMYADF.IL....NKSIEKQ.FRAFRRGFSMVTNESPLRaLF....RPEEIEMLICGSE.....-D.YDFNALEDACEYD....................GGFDKKS.Q.-.-TIRDFWEVVHG.FDDEKKCQLLQFTTGTDRVPVGGLSKLK-..-------.LIIA.........RN............-.-GPDSDRLPTAHTCFNVLLLPDYLNKEKLQERLLEAI-TY.SKGFGML
UBE3A_MOUSE/587-885 QLVVEEIF.....NPDIGMFTY--.-.----.---.-.-.---....-.-DEATKLFWFNPSSFET----....---EGQFTLIGI-LGLAIYN.......NCILDVHFPMVVYRKLM-.-.GKK........................................................-.---GTFR..DLGDSHPVLYQS.LKDLLEYEGS--.--.-.-............-.-.-...-.---VEDDMM..ITFQISQTD--.-.L---.-.-.-F.GNPMMYD.-LKEN..GDKIPITNENRKEF......................VISYSDY.IL....NKSVEKQ.FKAFRRGFHMVTNESPLKyLF....RPEEIELLICGSR.....-N.LDFQALEETTEYD....................GGYTRES.V.-.-VIREFWEIVHS.FTDEQKRLFLLFTTGTDRAPVGGLGKLK-..-------.MIIA.........KN............-.-GPDTERLPTSHTCFNVLLLPEYSSKEKLNVRLLKAI-TY.AKGFGML
Q873C0_NEUCR/1005-1322 LLLVREVF.....NPDHGMFVY--.-.----.---.-.-.---....-.-DEDSQYCYFNPASLEP----....---SEQYFLVGVVFGLAIYN.......STILDVALPPFAFRKLLMaApPPTla....................................................tsQpRQPMTYSldDLAEYRPRLASG.LRQLLEYDGD--.--.-.-............-.-.-...-.---VESTFC..LDFVVDIER--.-.Y---.-.-.--.GSTERVS.-LCPN..GERRPVTNANRREY......................VDLYVRY.LL....DTAVTRQ.FEPFKRGFYTVCGGNALS.LF....RPEEIELLVRGSD.....-EsLDISALKSAATYD....................NWSTKNP.VeTePTVGWFWELFEE.ASPADQRKLLLFITGSDRIPAGGAAALS-..-------.IRIA.........CL............-.-GEDCGRYPTARTCFNSLALWKYGSRERLKEVLWTAV-LE.SEGFGLK
O94275_SCHPO/482-807 LLLTRKVF.....SPEFGLFVNC-.-.----.---.-.-.---....-.-EESSNYLWFNYSHRSKE---....---IDYYHMSGILMGIAIHN.......SINLDVQMPRAFYKKLL-.-.QLP........................................................-.---LSFN..DLDDFQPSLYRG.LKELLLFEGD--.--.-.-............-.-.-...-.---VKNTYG..LNFTINLKA--.-.V---.-.-.--.EGFRTVE.-LKEG..GSELSVDNENRKEY......................VLRYVDY.LL....NTTVKKQ.FSAFFDGFMKVCGGNAIS.LF....QDNEISKLIRGSE.....-EvIDWELLKNVCVYDfydqnaisnsisesepsmtaSKYLCHSfVsKrKIILWFWDLISH.YSLKMQKLFLIFVTGSDRIPATGAHNFQ-..-------.LRIS.........VL............-.-GPDSDQLPISHTCFNHLCIWEYSSREKLKKKLDTAL-LE.TNGFNIR
HUL4_YEAST/570-892 FLLTKSLF.....NPMNGLFIY--.-.----.---.-.-.---....-.-IKESSRSWFAIDPPNFDKSKgknsQ--LELYYLFGVVMGLAIFN.......STILDLQFPKALYKKLC-.-.SEP........................................................-.---LSFE..DYSELFPETSRN.LIKMLNYTED--.--.-.-............-.-.-...-.--NFEDVFS..LTFETTYRNNNwIlNDSKsS.-.--.KEYVTVE.-LCEN..GRNVPITQSNKHEF......................VMKWVEF.YL....EKSIEPQ.YNKFVSGFKRVFAECNSIkLF....NSEELERLVCGDE....eQTkFDFKSLRSVTKYV....................GGFSDDS.R.-.-AVCWFWEIIES.WDYPLQKKLLQFVTASDRIPATGISTIP-..-------.FKIS.........--............LlGSHDSDDLPLAHTCFNEICLWNYSSKKKLELKLLWAI-NE.SEGYGFR
Q8SS57_ENCCU/454-746 QLLSQEI-.....KEDERLF----.-.----.---.-.-.---....-.-EHTENRIWIRPHEGD-----....---GEGYEAIGRIIAIALYN.......NVVLNIPFPSLFFKKLL-.-.DRR........................................................-.---PTLD..DLREISSGIATS.LRNLRRLSRD--.--.-.-............-.-.-...-.---EVDSLD..LRFVVEHSVD-.-.----.-.-.--.GIPRSYP.-LVKN..GEDIKLTSENMRLF......................IEKYVEF.HT....DALIKPQ.FESIKRGFYSIIDKDKLA.YL....DPKELEKIMMGSN.....-T.FDIKAIRSTTTYS....................-GFREDS.P.-.-IIVYFWEIFEA.FNRKKRKKLLQFITGNDRIPVSGPASLK-..-------.LVIM.........RN............-.-GCDTDRLPSSQTCFNTLLLPEYSSKDKLEGKLETAL-EL.TAGFFLL
Q9VL06_DROME/2313-2727 ALVAAEIQ.....RSDLCMWLCDDdLgEDTEnSTQsAeGnSKPvgyyV.-NRREHGIFPAPLPQNSEICE....-NVLKYFWFFGVFVAKVLQD.......MRLVDIPLSTSFLQLLCHnKvLSRnlqkvisdrrngdlsvvse.................dsdivetctkllrtdsnksnAfGGILSLE..NLKEIDPTRYQF.LQEMQNLLLRKQsIEfDdTisaekkhelineLkLqT..qNgLEVSLEDLA..LTFTYLPSSSI.-.----.-.-.--.YGYTQAE.-LLPN..GSSVNVTIDNLEAY......................CELLMNF.IL....QDGIAQQ.MKAFSDGFNEVFPLKKLA.AF....TPSEARMMICGEQ....fPH.WSREDIISYTEPK....................LGYNKDS.P.-.-GFQRFVNVLLS.MSGDERKAFLQFTTGCSSLPPGGLANLH-..-----PR.LTVV.........RK............-.VDAGVGSYPSVNTCVHYLKLPDYPTEEIMKERLLTATKE-.-KGFHLN
Q8JFV5_BRARE/2145-2576 ALVAAEFQ.....RTSLGIWLCDDdFpDD--.-ESrQvDlGGGlkppGyYVQRSCGLFPAPFPQDSDELE....-RITKLFLFLGIFLAKCIQD.......NRLVDLPISQPFFKLLCMgDiKSNmskllyqtrgesdchfseiqseasteegqdtysvgsfdedsksefildppkpkppaWyHGILTWE..DFELVNPHRALF.LKELKALSVKRRqILgNkSlsedekntrlqdLmLkNpmgSgPPLCVEDLG..LNFQFCPSSKV.-.----.-.-.--.HGFSSVD.-LKPN..GEDEMVTMDNAEEY......................VELMFDF.CM....HTGIQKQ.MEAFREGFNKVFPMEKLS.SF....SHKEVQMILCGNQ....sPS.WTAEDIVNYTEPK....................LGYTRDS.P.-.-GFLRFVRVLCG.MSSDERKAFLQFTTGCSTLPPGGLANLH-..-----PR.LTIV.........RK............-.VDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATME-.-KGFHLN
Q9SZN9_ARATH/390-757 TLLSHDLQ.....KASLGMWRSSSgDkVSMQiGRDeIeDgKPSaanrDiV-LAPLGLFPRPWPSTADISEggqfHKVIEYFRLLGRVMAKALQD.......GRLLDVPLSTAFYKLIL-.-.GQE........................................................-.---LDLH..DIVLFDAELGKT.LQELRVVVARKHyLEgVgGdn....sstisdLcLrG...-.--CRIEDLS..LEFTLP-----.-.----.-.-.--.-GYPEYI.-LR--..SGDEIVDITNLEEY......................ISLVVDA.TV....KRGVTRQ.IEAFRSGFNQVFDITSLQ.IF....TPSELDYLLCGRR.....EL.WEVETLAEHIKFD....................HGYNAKS.P.-.-AI---INVCYP.SSSDQQRAFCQFVTGAPRLPPGGLAVLN-..-----PK.LTIV.........RKhsstssaaangaGaSETADDDLPSVMTCANYLKLPPYSTKEIMYKKLLYAINEG.QGSFDLS
Q9LYZ7_ARATH/1160-1501 TLVSRAFQ.....NPDLGMWRNDCsFiVGKPvEHSgV.-.---....-.-LASSSGLFPRPWSGTSTTSD....--VLQKFVLLGTVVAKALQD.......GRVLDLPLSKAFYKLIL-.-.GQE........................................................-.---LSSF..DIHFVDPELCKT.LVELQALVRRKKlFAeAhGds....gaakcdLsFhG...-.--TKIEDLC..LEFALP-----.-.----.-.-.--.-GYTDYD.-LAPY..SANDMVNLDNLEEY......................IKGIVNA.TV....CNGIQKQ.VEAFRSGFNQVFSIEHLR.IF....NEEELETMLCGEC.....DL.FSMNEVLDHIKFD....................HGYTSSS.P.-.-PVEYLLQILHE.FDREQQRAFLQFVTGSPRLPHGGLASLS-..-----PK.LTIV.........RK............HgSDSSDTDLPSVMTCANYLKLPPYSSKEKMKEKLIYAITEG.QGSFHL-
Q9VN58_DROME/1878-2228 TTVVQHNT.....TTNNSSIITTTtTtSY--.---.-.-.---....-.-VHAVHGLFPLPLGKSSKLPQ...mTKAKAKFKFLGKFMAKAVMD.......SRMLDLPFSLPFYRWLV-.-.SEE........................................................-.---HSIGlaDLMRVAPEVQNT.LVRLQDLVRQREyILsDpNidamektekieqLdLdG...-.--CPIADLG..LDFVLP-----.-.----.-.-.--.-GHANIE.-LCRG..GRDTPVTVHNLHQY......................ISLVTYW.FL....IEGVQKQ.FEALREGFDSVFPIQRLR.MF....YPEELECVFCGSGseqqhSR.WEIKMLQESCRTD....................HGFHQDS.Q.-.-AIQYLYEILAS.YNRDEQRAFLQFVTGSPRLPTGGFKALT-..-----PP.LTIV.........RKt..........lDeNQNPNDYLPSVMTCVNYLKLPDYSSREVMRQKLKVAANEG.SMSFHLS
Q7PUQ4_ANOGA/1332-1696 ALVSTELQ.....RCDLGLWNDMGaTdGTGSpAVIgAgAvSY-....-.-VNAPRGLFPIPLSKTAKTSQ...iSRLKHKFKFLGKFMAKAVMD.......SRMLDLPFSIPFYRWML-.-.SEE........................................................-.---SSLGlsDLGQIAPEVQGT.LLRLNEIVKQRDqIQaDpTlnamektekieaLdLdG...-.--CPIADLG..LDFVLP-----.-.----.-.-.--.-GHPNIE.-LRRG..GRDMAVTINNLHQY......................ISLVTHW.FL....AEGVSRQ.FEALREGFDTVFPMSRLQ.MF....YPEELENVFCGSGiggtnQQrWDVRMLAESCRTD....................HGFNQDS.P.-.-AIQFFYDILAT.YNRDEQRLFLQFVTGSPRLPTGGFKALT-..-----PP.LTIV.........RKk..........mDgNQNPDEYLPSVMTCVNYLKLPDYSNRDVMRQKLKMAASEG.SMSFHLS
Q8K051_MOUSE/747-1102 ALVSQELQ.....RADLCLWRGEEvTlSNPKgSQEgTkY.---....-.-IQNLQGLFALPFGRTAKPAH...iAKVKMKFRFLGKLMAKAIMD.......FRLVDLPLGLPFYKWML-.-.RQE........................................................-.---TSLTshDLFDIDPVVARS.VYHLEDIVRQKKrLEqDkSqtkeslqyaletLtMnG...-.--CSVEDLG..LDFTLP-----.-.----.-.-.--.-GFPNIE.-LKKG..GKDIPVTIHNLEEY......................LRLVIFW.AL....NEGVCRQ.FDSFRDGFESVFPLCHLQ.YF....YPEELDQLLCGSK.....ADtWDAKTLMECCRPD....................HGYTHDS.R.-.-AVKFLFEILSS.FDNEQQRLFLQFVTGSPRLPVGGFRSLN-..-----PP.LTIV.........RKt..........fEsTENPDDFLPSVMTCVNYLKLPDYSSIDIMRDKLLIAAREG.QQSFHL-
Q7S5Y8_NEUCR/1585-1932 STVSKEFS.....KRKLKLWRDNElNgDDDF.---.-.-.---....-.-VSGPTGLFPRPLSDEFASSEe..gEKILQLFKVLGKFVARSMID.......SRIIDINFNPLFFRVGD-.-.---........................................................StATRPTLA..TIKSVDPVVARS.LMTIKKFSLAKKeIDeDpNrsavqkvadtenItIdN...-.--FKIDDLY..LDFTLP-----.-.----.-.-.--.-GYPEVE.-LVSN..GSQTRLTIENVDLY......................LEKVIDM.TL....GSGVRRQ.IEAFRSGFSQVFPYSALS.SF....TPDELCTLFGRVD.....ED.WSLETLNDSIKAD....................HGYNMDS.K.-.-SVRNLLQIMSE.LTLAERRDFLQFTTGSPKLPIGGFKSLN-..-----PM.FTVV.........CKp..........sEaPYTSDDYLPSVMTCVNYLKLPDYSDIGVLKKQLFTAMKEG.QGAFHL-
UFD4_YEAST/1148-1482 SVVSKYFA.....RKSLNMWRCNSySyRSEMdVDTtD.-.---....-.-DYITTLLFPEPLNPFSNNEK....--VIELFGYLGTFVARSLLD.......NRILDFRFSKVFFELLH-.-.RMStpn.................................................vttvPsDVETCLL..MIELVDPLLAKS.LKYIVANKDDN-.--.-.-............-.-.-...-.--MTLESLS..LTFTVP-----.-.----.-.-.--.-GNDDIE.-LIPG..GCNKSLNSSNVEEY......................IHGVIDQ.IL....GKGIEKQ.LKAFIEGFSKVFSYERML.IL....FPDELVDIFGRVE.....ED.WSMATLYTNLNAE....................HGYTMDS.S.-.-IIHDFISIISA.FGKHERRLFLQFLTGSPKLPIGGFKSLN-..-----PK.FTVV.........LKh..........aEdGLTADEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAIEEG.AGAFLL-
Q8IC24_PLAF7/3588-3888 NVISNKTK.....-----------.-.----.---.-.-.---....-.-KTSSDKIKKKTIHIDQDTLE....NRLFKYFKLLGQLCAKILTD.......NRNINVNLHPLFWYLVM-.-.SNS........................................................SyINLSKFH..HYHAIDRINMNS.INKLLEYRNE--.--.-.-............-.-.-...-.-NKNVEDLH..LDFTLL-----.-.----.-.-.--.GSNPPVE.-LIPN..GSNIPVTNENLNLF......................INKTIEY.SL....YDGIKFQ.IWAFRYGFSTIAPLVCTN.MF....DENEICEFLFGSNi..enDEhWTKTHLSTYIKPD....................HGYTNDS.I.-.-TFITLIEILSE.FNKEERKQFVKFCTGTSALPNNGFAALK-..-----PL.MKVV.........KK............-.--EDNNDLPSVMTCTNYLKIPDYKNKEKLRNRLIYAINEG.-----IY
Q7QZQ9_GIALA/875-1158 TVITREDL....hDVDEELYFSLTnLwKHA-.---.-.-.---....-.-HNEDSQLTVNLQESSDPILT....------FVGLGAILTEIVSE.......EL---VSMNRTVSVRTI-.-.---........................................................-.---SHFG..DFLCSNSFPPNSiLWQLKELVKDRHhI-.-.-............-.-.-...-.---------..-----------.-.----.-.-.--.-------.-LTAPydIELLPVNLRTLPLF......................IRLKQ--.IA....TIYNKKI.FEFIRSGFLSMAKARSLA.MF....TASDLDLALTGEV.....-D.LNFSLLEPFTAYE....................NPYSSSH.P.-.-NIKNFWRIVAE.LTQEQQRRLLRFITGSDRVPAGGVQNIG-..-------.LKII.........PN............-.-GDDDSRLPGAHTCFNILCLPSYSSKETLMNRLLCAI-EC.CEGFGLM
Q9N9M2_LEIMA/5123-5428 TQMSAELM.....STSLALFLPSAnMaSEL-.---.-.-.---....-.-GEVRDSYVVNPLCAPPLELH....-----MYRFIGRLMGGCLRG.......GEPLSLYLSSALWKYLVGeAaDDT........................................................-.-------..DMARIDMATLNA.LGYVEQLAGF--.--.-.-............-.-.-...-.-----PSPSgaLGGSGDSDDAVrDeELAElCpRgFSlLNDAGIVeELVPG..GEQIPVTVASGGLY......................TRLVREH.KL....YRTGAAQ.LRALQQGFHEVVPLCSVS.GL....KWYELEELVCGQC.....-D.YDPDALLDAARYE....................GLSPTDV.-.-.-RVRFLRSVLRG.FTRHQRALFMRFVSGRERLPPGMH-----..-------.LKIM.........--............-.----------PDDAPRVAPIPPMTP-----DRAAPSLQSV.SPHCRQR
Q8IW65_HUMAN/323-635 TEMCQELE.....TGIVDLLIPSPnAtAEV-.---.-.-.---....-.-GYNRDRFLFNPSACLDEHLM....-----QFKFLGILMGVAIRT.......KKPLDLHLAPLVWKQLC-.-.CVP........................................................-.---LTLE..DLEEVDLLYVQT.LNSILHIEDS--.--.-.-............-.-.-...-.-GITEESFHemIPLDSFVGQSAdGkMVP-.-.-.--.-------.-IIPG..GNSIPLTFSNRKEY......................VERAIEY.RL....-HEMDRQ.VAAVREGMSWIVPVPLLS.LL....TAKQLEQMVCGMP.....-E.ISVEVLKKVVRYR....................EVDEQHQ.-.-.-LVQWFWHTLEE.FSNEERVLFMRFVSGRSRLPANTADISQR..-------.FQIM.........KV............-.-DRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCrSIDMDNY
Q9Y4D8_HUMAN/2681-3004 LLCPSSAV.....-----------.-.----.---.-.-.---....-.-NKNKGKYILTPSPITYGEEQ....-----LLHFLGQLLGIAIRA.......DVPLPLDLLPSFWKTLV-.-.GEP........................................................-.---LDPE.qDLQEADILTYNY.VKKFESINDE--.--.-.-............-.-.-...-.-----TELEalCAEIASQHLATeSpDSPNkPcCrFTyLTMTGEEvELCSR..GRHILVAWENKDIY......................AAAIRSL.RL....RELQNVEcVTAVRAGLGSIIPLQLLT.ML....SPLEMELRTCGLP.....-Y.INLEFLKAHTMYQ....................VGLMETD.Q.-.-HIEFFWGALEM.FTQEELCKFIKFACNQERIPFTCPCKDGGpdTAHVPPYpMKIA.........PP...........dGtAGSPDSRYIRVETCMFMIKLPQYSSLEIMLEKLRCAI---.HYREDPL
Q7QUT2_GIALA/426-723 SALSHDGL.....APNMIV-----.-.----.---.-.-.---....-.-SESSNELTMSPTVLPLDAFC....---------MGWLIGRCLCY.......GISLSSQLSRLFISLAM-.-.NVS........................................................-.---PTLA..DIIHFEPGLGNL.IAEAEKDDHS--.--.-.-............-.-.-...-.---------..-----------.-.----.-.-.--.-------.-LAIL..KESIPALSNTSCWYksfkfcanfnnkkkrlcfrrinLEKVIVS.YL....YPRSSKA.LHYLRSGFRTAIPAPGCY.FI....DVSLVHAIVVGAP.....-S.ISIDDWREHSVVD....................GCWSNPE.-.-.-VVEWFWELLRE.-NPELAVGILRFSCGISVPPQEGFCNLGQplFLGQHPLpFTLR.........--............-.-PCSKDRLPMGHTCTNTLQIPLAESKDDLLRALKVAAR--.VSAMDIK
Q7R629_GIALA/2319-2632 NLVTSDLM.....NHCQAFSRKNY.-.----.---.-.-.---....-.-LPKTCKTSASPLKRQSGYLE....------YIILAYLISRSITE.......FLSLSFDIPTTLLRRIL-.-.GLS........................................................-.---FKAQ..DIMLSSPEMYYGnLIALLNVDRS--.--.-.-............-.-.-...-.------RFEdcVGLDI------.-.----.-.-.--.TDVPFDD.-AIDT..EHSTIKYSGDTMDH......................VNMMVA-.EI....TNRRSVP.INVVAKLVQRSLPSVDLR.IF....TPVELGLVISGIN.....-E.--LSSSQLVSLFKwihp...........ppdvsSSLVSQA.-.-.-TELAFSTVLNE.LTFEERADFLCFVTGSSRIPPIGFEPE--..-------.LKVQ.........RLaadge.tpdtkpEdIDPKKLRLPSASTCFHSLKLPPYCNPADLKRVLKISVSE-.GKTFEFA