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PANDIT
Protein and Associated NucleotideDomains with Inferred Trees

PF00503 alignment
(24 sequences with 402 aa)


GPA8_DICDI/5-351 QSRVQVEDKTNEQLDKYLVQAGKEGLLDFRILLLGAGESGKSTVVKQLKSIYKIQVDDDELHSYAVNIHKNTVLCMQVLLEAGETLGIELTDPET--.-KKRAINVKSFQFEPEV.....-KQMPVSIGLDIEELWRDEDIQKIWDRR...SEY.WFLDATPYYFENIQRFLDDDFVPTEEDCIMTRVRTTGISVTEFDE........GPVHFRVVDVGGQRNERKKWIHCFDD.VKALLFVVNLAGYDQVMFEDPS..QNRMQESLTLFGQICNNPIFSETPTFLVLNKKDLFEQMIQKTD--LSKCFPDYK---........-GG-.SDVKTALEFIQMKYQQKIQESN---...........KPLHTFHIAARYKKDIKYTWEEAKGILLEENKKVLMK
GPA1_ARATH/11-382 HTEDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKEFAQNETDSAKYMlS-SESIAIGEKLSEIGGr..ldYPRLTKDIAEGIETLWKDPAIQETCARG...NEL.QVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPvg..enkkSGEVYRLFDVGGQRNERRKWIHLFEG.VTAVIFCAAISEYDQTLFEDEQ..KNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVS........SGK-.QEIEHAYEFVKKKFEELYYQNTAPDr........vdRVFKIYRTTALDQKLVKKTFKLVDETLRRRNLLEAGL
GPA7_DICDI/44-390 LTRYREQKAVNKQIEKQLKEEKKIMDSELKLLLLGTGDSGKSTVVKQMKILHLEGYSQEERINQRQFVYRNIIEIAYSIIRGCGVLNLTIPSQFD--.---SICSSIEEIYETKN.....YTNLDKNVLKGVAELSKNESFINAANNS..gSNF.QLHSSSQYFLDDIARFSEEDYIPTDQDILYTRVASTSVSETRFSV........RGIKFRMIDVAGQRGHRDKWIHHFSE.VTAILFVISLCEYDQVLEEDGK..TNRMIESIKVFGDIINQRLFKDIPIILFLNKRDLFAEKIKKTG--ISICFPDYT---........-GPS.DDYEQSLVFLKKKILSANK--TS--...........KAVYTNVTTATDTTNIGHVFEAVKDILTRQTMEEGGI
GNAS_SCHMA/12-378 SEDAKTRSDANKQIEKLIEKEKKNFKSTHRLLLLGAGESGKSTIVKQMRILHIDGFSEREKKEKIDAIRKNLRDAICSIAGAMGSLKPPVKLELSEN.-RKLRDYILETASKPD-.....-FDYPPEFFTYCAKLWKDGGIQETFERS...NEY.QLIDCAKYFLDKALEVGAPNYIPSEQDILRCRVLTSGIFETKFSV........DKVNFHMFDVGGQREERRKWIQCFND.VTAIIFVAACSSYNMVLREDPS..QNRVKESLELLASIWNNRWLRNISVILFLNKQDLLTEKVLAGKSKIEVYFPHYATYQapadtlaeYRHEnSEVVRARFFFRDEFLKVTSNNNGGR...........HYCYPHLTCAVDTENIRRVFNDCRDIIQRMHLRQYEL
GNAL_HUMAN/15-380 GVDEKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPEN.-QFRSDYIKSIAPITD-.....-FEYSQEFFDHVKKLWDDEGVKACFERS...NEY.QLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQV........DKVNFHMFDVGGQRDERRKWIQCFND.VTAIIYVAACSSYNMVIREDNN..TNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTvpedatpdAGED.PKVTRAKFFIRDLFLRISTATGDGK...........HYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYEL
GNAL_DROME/105-456 TPEELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRIIHGVNFDYELLLEYQSVIYQNVIRGMQVLLDAREKLNIAWGSD----.--GREQDAYDAKLMECNs...lDVPKFMEYAPPISRLWQDRGIRRAFERR...REF.QISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATKGVYEFCVKV........QNIPFVFVDVGGQRTQRQKWTRCFDSsVTSIIFLVSSSEFDQVLAEDRK..TNRLEESKNIFDTIVNNATFKGISIILFLNKTDLLEQKVCNPETDIRWYYPHFN---........-GNP.HSVLDVQNFILQMFMSVRRSSSI--...........SRIYHHFTTAIDTRNINVVFNSVKDTILQRNLNALML
GNA13_MOUSE/21-376 TNGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNKNQL.-HGDKLMAFDTRAPMAAqg.mvETRVFLQYLPAIRALWEDSGIQNAYDRR...REF.QLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTKGIHEYDFEI........KNVPFKMVDVGGQRSERKRWFECFDS.VTSILFLVSSSEFDQVLMEDRQ..TNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQ--VVSIKDYFLEFE---........-GDP.HCLRDVQKFLVECFRGKRRDQQQ--...........RPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLML
GNA12_HUMAN/29-379 RDAEREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEK.-HGMFLMAFENKAGLPV.....EPATFQLYVPALSALWRDSGIREAFSRR...SEF.QLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVI........KKIPFKMVDVGGQRSQRQKWFQCFDG.ITSILFMVSSSEYDQVLMEDRR..TNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVS--IKKHFPDFR---........-GDP.HRLEDVQRYLVQCFDRKRRNRS---...........KPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIML
GPA2_NEUCR/7-355 GKDDEAEASRSRELDKQIRADEKRLSKEVKLLLLGAGESGKSTILKQMKLIYAQGFSKNEKLEWRPVIFANILQSFRLIFDAMNEFNIKLEDEDN--.-EKNMVQMMVDYEMRG-.....DEPLPLEYFEPAKKLWQDSGVRQAIEKG...NEF.ALHDNLQYFCSDLDRLWDRNYVPSDQDLLRSRLRTTGITETVFDL........GQLTYRMFDVGGQRSERKKWIHCFEN.VNCLLFLVAISGYDQCLVEDKD..GNQMNEALMLWESIANSHWFTKSALILFLNKIDLFKEKLPRSPI-TNHGFTDYH---........-GPP.DDSKQASKYFMDKFRALNR-NPD--...........KEIYGHFTNATDTNLLKITMGSVQDMIIQRNLKQLIL
GPA2_CAEEL/6-355 SEEEKVGTLKSRAIDKEIKQLQTSEERTVKLLLLGAGECGKSTVLKQMRLLTSKQYTDEELLTQAKLVYTNIVIEMDHLVKAMPAAGLNFSDPMR--.-EHDVHMLTLYIKDMQH.....KN-FQQDAADHVEKLWKDPVVKRLYAERkelNIR.DIGDNTEYFFENLPRISKEDYHPNATDTLLLRTKTTGIVEVGFEI........KKVKFRVFDVGGQRSERKKWIHCFED.VNAIIFIAALSEYNEVLFEDET..TNRMIESMRLFESICNSRWFHNTNIILFLNKKDLFEEKIKKE--NIHKAFPEYR---........-G-E.QNYAETVAFIKTKFEALSN-NPK--...........KTFYVHETCATDTNQVQKILDSVISMIIQSNLHKSGL
GPA3_CAEEL/6-353 SAEDKELTLKSKAIDKEMMQNHMSQQKVVKLLLLGAGECGKSTVLKQMRILHDHGFTAEEAEQQKSVVFNNTLQAMTAILKGMEALRMTFDKPIR--.-ENDAKFVMESHKMLQE.....AKVFPEELANAIQALWNDKAVQQVIAKG...NEF.QMPESAPHFLSSLDRIKLPDYNPTEQDILLSRIKTTGIVEVKFQM........KSVDFRVFDVGGQRSERKKWIHCFED.VNAIIFIAAISEYDQVLFEDET..TNRMIESMRLFESICNSRWFINTSMILFLNKKDLFAEKIKRTS--IKSAFPDYK---........-GA-.QTYDESCRYIEEKFDGLNANPE---...........KTIYMHQTCATDTDQVQMILDSVIDMIIQANLQGCGL
GPA1_CAEEL/6-356 SRELVAQAKQNKIINTELDKAKKTDENIIKLLLLGAGESGKSTVLKQMKIIHNSGFSQEEISNKRNVVCANTVQAMGALLDGMKQLQFDFSTRVC--.-NAHEKLIRETLNDKAE.....YGPFSDAMFNALTELWADKGVQCAYDKR...EFF.YLHDSAKYFFDAIARVHTPNYVPTENDILHTRVPTMGVIEVNFTI........KGKFFRVFDVGGQRSQRKKWIHCFDD.AKAMIYVASLSEYDQVLLEDNT..TNRMHESIQLFKQVINNKYFVNTSVILFLNKIDLFEEKIVTKKRSLGIAFESFS---........-GPS.QDLNAAVAFVEKKYRSMAENKE---...........KNIYCHHTCATDTQQVQYVLDAVLDTILSTKLKGCGL
GNA15_MOUSE/15-373 TEEEKTAARIDQEINRILLEQKKQEREELKLLLLGPGESGKSTFIKQMRIIHGVGYSEEDRRAFRLLIYQNIFVSMQAMIDAMDRLQIPFSRPDSKQ.-HASLVMTQDPYKVST-.....---FEKPYAVAMQYLWRDAGIRACYERR...REF.HLLDSAVYYLSHLERISEDSYIPTAQDVLRSRMPTTGINEYCFSV........KKTKLRIVDVGGQRSERRKWIHCFEN.VIALIYLASLSEYDQCLEENDQ..ENRMEESLALFSTILELPWFKSTSVILFLNKTDILEDKIH--TSHLATYFPSFQ---........-GPR.RDAEAAKSFILDMYARVYASCAEPQdggr..kgsraRRFFAHFTCATDTQSVRSVFKDVRDSVLARYLDEINL
GNAQ_DROME/6-352 SEEAKEQKRINQEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGYIKLVFQNIFMAMQSMIKAMDMLKISYGQGEHSE.-LADLVMSIDYETVTT-.....---FEDPYLNAIKTLWDDAGIQECYDRR...REY.QLTDSAKYYLSDLARIEQADYLPTEQDILRARVPTTGILEYPFDL........DGIVFRMVDVGGQRSERRKWIHCFEN.VTSIIFLVALSEYDQILFESDN..ENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIM--YSHLVDYFPEYD---........-GPK.QDHAAAKQFVLKKYLACNPDPE---...........RQCYSHFTTATDTENIKLVFCAVKDTIMQNALKEFNL
GPA1_DICDI/9-354 ELGSPEEIKANQHINSLLKQARSKLEGEIKLLLLGAGESGKSTIAKQMKIIHLNGFNDEEKSSYKTIIYNNTVGSMRVLVNAAEELKIGISENNK--.---EAASRISNDLGDHF.....NGVLTAELAQDIKALWADPGIQNTFQRS..sEFQ.LN-DSAAYYFDSIDRISQPLYLPSENDVLRSRTKTTGIIETVFEI........QNSTFRMVDVGGQRSERKKWMHCFQE.VTAVIFCVALSEYDLKLYEDDT..TNRMQESLKLFKEICNTKWFANTAMILFLNKRDIFSEKITKTP--ITVCFKEYD---........-GP-.QTYEGCSEFIKQQFINQNE-NPK--...........KSIYPHLTCATDTNNILVVFNAVKDIVLNLTLGEAGM
GPA2_DICDI/3-354 CASSMEGEKTNTDINLSIEKERKKKHNEVKLLLLGAGESGKSTISKQMKIIHQSGYSNEERKEFKPIITRNILDNMRVLLDGMGRLGMTIDPSNS--.--DAAVMIKELTSLQASivtdcWGELNEDQGKKIKALWTDPGVKQAMRRA...NEFsTLPDSAPYFFDSIDRMTSPVYIPTDQDILHTRVMTRGVHETNFEI........GKIKFRLVDVGGQRSERKKWLSCFDD.VTAVVFCVALSEYDLLLYEDNS..TNRMLESLRVFSDVCNS-WFVNTPIILFLNKSDLFREKIKHVD--LSETFPEYK---........-GG-.RDYERASNYIKERFWQINK-TEQ--...........KAIYSHITCATDTNNIRVVFEAVKDIIFTQCVMKAGL
GPA1_NEUCR/7-352 TEEKEGKAR-NEEIENQLKRDRMQQRNEIKMLLLGAGESGKSTILKQMKLIHEGGYSRDERESFKEIIFSNTVQSMRVILEAMESLELPLADQRV--.-EYHVQTIFMQPAQIE-.....GDVLPPEVGNAIEALWRDAGVQSCFKRS...REY.QLNDSARYYFDNIARIAAPDYMPNDQDVLRSRVKTTGITETTFII........GDLTYRMFDVGGQRSERKKWIHCFEN.VTTILFLVAISEYDQLLFEDET..VNRMQEALTLFDSICNSRWFIKTSIILFLNKIDRFKEKLPVS--PMKNYFPDYE---........-GG-.DDYAAACDYILNRFVSLNQ-HET--...........KQIYTHFTCATDTTQIRFVMAAVNDIIIQENLRLCGL
GPA1_COPCO/7-351 GVDDEAKAR-NDEIENQLKRDRVMAKNEIKMLLLGAGESGKSTVLKQMKLIHHGGYSDQEKDSYKEIIFSNTVQSMRAILDALPALDLALQPAN---.-DARRATILAVPGQIE-.....AEVLPRDIADAIRQLWADPGLKEAVRRS...REF.QLNDSAVYYFNSIDRMSAPGYLPTDQDILRSRVKTTGITETTFKV........GELTYKLFDVGGQRSERKKWIHCFEN.VTALVFLVSLSEYDQMLYEDES..VNRMQEALTLFDSICNSRWFVKTSIILFLNKIDLFAEKLPAR---RSTYFPDFT---........-GG-.DNYDAACDYLLHRFVSLNQSAAT--...........KQIYAHYTCATDTQQIKFVLSAIQDILLQLHLRECGL
GNAZ_HUMAN/5-353 SSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPDR--.-AYDAVQLFALTGPAES.....KGEITPELLGVMRRLWADPGAQACFSRS...SEY.HLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIVENKFTF........KELTFKMVDVGGQRSERKKWIHCFEG.VTAIIFCVELSGYDLKLYEDNQ..TSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIP--LTICFPEYK---........-GQ-.NTYEEAAVYIQRQFEDLNRNKET--...........KEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGL
GNAO1_BOVIN/5-352 SAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKER--.-KADAKMVCDVVSRMED.....TEPFSPELLSAMMRLWGDSGIQECFNRS...REY.QLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTF........KNLHFRLFDVGGQRSERKKWIHCFED.VTAIIFCVALSGYDQVLHEDET..TNRMHESLMLFDSICNNKFFIDISIILFLNKKDLFGEKIKKSP--LTICFPEYT---........-GS-.NTYEDAAAYIQAQFESKNRSPN---...........KEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGL
GNAI_DROME/7-354 TARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQEECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSR--.--TDIARQFFTHASAAD.....EGILLPEIVLLMKKLWADGGVQQSFARS...REY.QLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSC........KQLHFKLFDVGGQRSERKKWIHCFEG.VTAIIFCVALSGYDLVLAEDEE..MNRMIESLKLFDSICNSKWFVETSIILFLNKKDLFEEKIKRSP--LTICFPEYT---........-GT-.NTFEEAANYIRMKFENLNKRKDQ--...........KEIYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGL
GNAT1_BOVIN/1-348 GAGASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSAR--.-QDDARKLMHMADTIE-.....EGTMPKEMSDIIQRLWKDSGIQACFDRA...SEY.QLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSF........KDLNFRMFDVGGQRSERKKWIHCFEG.VTCIIFIAALSAYDMVLVEDDE..VNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKKAH--LSICFPDYN---........-GP-.NTYEDAGNYIKVQFLELNMRRDV--...........KEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGL
GPA2_SCHPO/7-353 LSESGESKKLNSKIEKQIENASKKDKKIYKVLLLGASDSGKSTISKQIKILNKNGFSQEEIMTFIPVIRRNLLESAKTLVKIIVQKGINLDPLG---.--THNCEIIEKFNPTPG.....-ELINANIGQAITSLWSANSVRSCTYGN...-DS.VLIDSAPYFFSRADEICSRHYVPTIDDILRSRNSTLGISEISFTL........DHLQIRMFDVGGQRTERRKWIYCFEN.VNSIIFCVSLNDYDKKLYERAApeRNRLVESISLFDSIINSQWFMHSSIILFLNKFDLFRKKLEHVP--FQDYFPQYE---........-GK-.NSVKSITRYILWLFVNPSINRAK--...........HNIYPHITTAVDTSNIKVVFSAVKETILQHSLKEAGM
GNAF_DROME/20-398 MTHKEDQYPVSLDHHVLKDMAKGVRDTTVKILLLGTAESGKTTIIKQMRILHINGFTDDERREKIPEIYQNIHESILQLVGQMGVLGIDFGSCTS--.-ERSADYILSLPGSAP-.....-EYMNEEYCDHVTTLWNDVGIRACYDRS...NEF.PLLDSAKYFLDNFVRISDAEYIPSTEDILHSRKITTGISQITFRVpipksmggGEQQFQMYDVGGQRDQRNKWIQVFEG.IQAVLFLISCSEFDQNLREDPS..QNRLQEALKLFRAVWQNRFLASAGLIVFLNKYDIMERKIRAGK-HIVDYFPEYEDFCkr....pqQDNCfGESDWTKMFIKQKLVDITQEPFKRHsrnqvdlgtseRECYYHFTVATDTRCIRDVFCDVQKMILSENVSSMGL