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PANDIT
Protein and Associated NucleotideDomains with Inferred Trees

PF00493 alignment
(65 sequences with 451 aa)


Y3513_METJA/258-581 DVKNIKKV.AKRG..DIIDILADILIPPLLC..DDAiVRKAILIQQIAPYL.-..--ED.---..-IGKINILLVTEVG..-IDKTAILKRI.G.-NIPGNNFINIAALKEEELaTPYDKRSNILGK...FYTVCGGVIPRTLGVLCIDDFNENNK-LSTKLSEAFERNVLTTNKGS.-FYC.VPAECSFLCACYPKtkFRKFDQKKSIIKQIGISSILLKNFDLI.FPIRD.IPDKDRDEEVAKYIFLKYINSD-...------.-.--.-.-.-.-.--...........---NEEIEGYDYVFvDvGGEK..--.-.--.-..........--.---.IKIDFEFLKKYVVYS.R-QITP..K....ITDEV.IEKISNWYDEMRK----.---.--N.-----HYITAKQLNTVIKLSIAVARAKLKECVDEDDVKEAIDIIMHYLK
Y363_METJA/339-669 DLELINRI.AKDK..NVIQKLSDYAFREVTG..YDM.IKRAVLLQLVSSGT.N..ID--.---..MRTSIHILMISDPG..-VGKSTLMESL.I.QKFPFVKKVYAVTSSGPGL.VGSVVREKAEFGd.sWVLKAGVLTEADGGVVCIDEFSRNKE-VYDYLLGVMEQQKIEINKAGvIDAV.LPARVAILAACNPR..FGRFNPDLTVWEQINLPKELLDRFDLI.FVIKD.KIDKKKDEDIADFSIDNYNSK--...------.-.--.-.-.-.-.--...........--VRERKGKSSGK-.-.----..--.-.--.-..........-KfVINgVELNDELLLKYVLYA.R-QIEP..E....ISDEA.RKIIKEYYVSVRKMSE-.---.--A.--KGTFGISARQLGSIIRLAVAHAKLRLSEVVKAVDAEEAIRLVDTCLK
Y1489_METJA/271-595 DIENIKKI.AKRK..DVVNILADRLIPEIKG..HSA.IKKAVLLQQIKGVK.K..--PG.---..KRADIHILLITDPG..-IGKTVILRKI.A.-EIPGNLYGSVTTATGVGL.TAAVVREKTEIGedtWVIKPGLLVKAHKGTACIDELTVNKE-LQSYVLEAMESQTIHISKGG.INAK.LPAECAILAACNPR..WGRFNPEVSVAEQINIPAPLLSRFDLI.FPIRD.VSDKDKDKDIAEYIVDLHRAY--...------.-.--.-.-.-.-.--...........--LDEKINREMGLD.-.----..--.-.--.-..........-YlEVDgVKIDKEFIIKYIYYA.R-QKKP..I....ISEKA.KELFVNYYVEMRKKHQ-.---.---.-------ITARQLEAAIRIAEAHAKAKLKDVVDEEDAKEAINIITECLK
Q7R0H3_GIALA/302-626 LATDLSVL.REKA..IPLHVLIASFAPRIHG..RED.EKLACLCSLVGGNE.I..VVPD.-MK..VRGNINTLFVGDPG..-CAKSALLKFT.C.TIAERGIYVAGRGASGAGL.TTAAIRIPGTTD...YSLEGGALVIADQGVCALDELDKLEEADRTAIYEVMEQGTISVAKAG.ITAT.LNARATVVAAANPK..FSIWDPSISVASNINIPEALISRFDIL.FVIRD.KIHEEEDMNLSLHVANLHKHA--...------.-.--.YdMySaGvSD...........-----AQSTKI---.-.----..--.-.--.-..........--.---.--LTEKELQAYIAVA.K-NLRP..A....VPQHL.LDTYVMTYIQDRKERE-.---.---.------FITPRALLATIRISQAIAKLRLSDSVSADDVAKARDLLAAAEK
MCM5_CAEEL/317-673 EERMFKTL.AQRK..DAYELIAKSIAPSIYG..SAD.IKKSIACLLFGGAR.K..KLPD.GIT..RRGDINVLLLGDPG..-TAKSQLLKFV.E.QVSPIGVYTSGKGSSAAGL.TASVIRDPQSRS...FIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAG.ITTT.LNSRCSVLAAANSV..YGRWDESRGD-DNIDFMPTILSRFDMI.YIVKD.THDVLKDATLAKHVIEVHVNASA..aKERDIA.G.VP.-.-.-.-.--...........KTATTDSDGVMTMF.D.----..--.-.--.-..........--.--TdGFLTIEFLKKFVTYA.RLNCGP..R....LTPQA.SEKLVNHYVKMRNPVVNaDAFkSGKkAHNSAIPITVRQLEAIVRIAESIAKMELQQFATDKHVEEALRLFRVSTI
Q9VGW6_DROME/315-648 EEEHFRRM.AASG..DIYERLSQSLAPSIFG..SRD.IKKAITCMLFGGSR.K..RLPD.GLC..RRGDINVLLLGDPG..-TAKSQLLKFV.E.KVAPIAVYTSGKGSSAAGL.TASVMKDPQTRN...FVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAG.ITTT.LNSRCSVLAAANSI..FGRWDDTKGE-ENIDFMPTILSRFDMI.FIVKD.IHDESRDITLAKHIINVHLSS--...------.-.--.-.-.-.-.--...........---NKSAPSEP---.-.----..--.-.--.-..........--.--AeGEISLSTFKKYIHYC.RTHCGP..R....LSEAA.GEKLKSRYVLMRSGAGQqEKA.SDK.--RLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEALRLFQVSTL
Q8X0Y2_NEUCR/309-641 EEQEFLEL.SRRP..DLYNVMAECIAPSIYG..NKD.IKKAILCLLMGGSK.K..ILPD.GMR..LRGDINVLMLGDPG..-TAKSQLLKFV.E.KVAPIAIYTSGKGSSAAGL.TASVQRDASTRE...FYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAG.ITTI.LNARTSVLAAANPI..FGRYDDMKTPGENIDFQTTILSRFDMI.FIVKD.EHERGRDERIAKHVMGIHMGG--...------.-.--.-.-.-.-.--...........RGVEERIEA-----.-.----..--.-.--.-..........--.---.-EIPVEKMRRYISYC.RSRCAP..R....LSPEA.AEKLSSHFVAIRKQVHAsELE.ANA.--RSSIPITVRQLEAIVRITESLAKLTLSPVATEKHVDEAIRLFLCSTM
MCM5_YEAST/353-689 EEEEFLQL.SRNP..KLYEILTNSIAPSIFG..NED.IKKAIVCLLMGGSK.K..ILPD.GMR..LRGDINVLLLGDPG..-TAKSQLLKFV.E.KVSPIAVYTSGKGSSAAGL.TASVQRDPMTRE...FYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAG.ITTV.LNSRTSVLAAANPI..YGRYDDLKSPGDNIDFQTTILSRFDMI.FIVKD.DHNEERDISIANHVINIHTGNA-...------.-.--.-.-.-.-.--...........NAMQNQQEENG---.-.----..--.-.--.-..........--.---.SEISIEKMKRYITYC.RLKCAP..R....LSPQA.AEKLSSNFVTIRKQLLInELE.STE.--RSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTM
MCM5_SCHPO/309-642 EEEEFLEI.SRTP..NLYDIISNSISPAIYG..NVD.IKKAIACLLFSGSK.K..ILPD.GMR..LRGDINVLLLGDPG..-TAKSQFLKFV.E.RLAPIAVYTSGKGSSAAGL.TASIQRDSVTRE...FYLEGGAMVLADGGIVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAG.ITTI.LNSRTSVLAAANPI..FGRYDDMKTPGENIDFQSTILSRFDMI.FIVKD.EHDETKDRNIARHVINLHTNL--...------.-.--.-.-.-.-.--...........---QESSET-----.-.----..--.-.--.-..........--.-LAiGEIPFDKFRRYINYC.RHKCAP..N....LDAEA.AEKLSSQFVAIRKLVHQsEQD.SNS.--RSTIPITVRQLEAIIRITESLAKMSLSPIASEAHATEAIRLFLTSTL
Q8SRS4_ENCCU/268-615 EEESFKKL.SKA-..DIYERISRSIAPSVYG..HED.VKRALACMLFGGTR.R..VLED.KVT..LRGDINVLLLGDPG..-MAKSQLLKFM.E.LVSPVGVYTSGKGSSAAGL.TASVIRDS-GGE...FYLEGGALVLADNGICCIDEFDKMDEHDRVAIHEAMEQQTISIAKAG.ITTM.LNTRTSILAAANPV..FGRYDDYKTPDENIEFGATILSRFDCI.FILKD.KHG-PNDIILAKHVLSVHQNKA-...-REDNEcQnGL.-.-.-.-.--...........---HDDQEEQI---.-.--SGsdRSpD.--.-..........--.---.-IIPIHTIKRYVQYA.RSKVFP..T....LSEAA.SKQLSRYYVNTRKEVRQlEQS.TLK.--RNAIPITVRQLEAIIRIGESLAKMELSQIVTEKHVEEAIRLFKVSTM
Q9U3X1_ENTHI/197-522 DDRRMKEV.ART-..ITKEKLIKSIAPAICG..YDD.IKEAVLCLMLGGSG.K..ALPD.GTH..LRGDINVLLMGDPG..-TAKSQLLKFV.Q.MATPIGVYTSGKGSSAAGL.TAAVNKDSSTGE...FYLNGGALVLGDGGVVCIDEFDKMNEVDRVAIHEAMEQQTISIAKAG.ITAV.LNARSAVLAAANPS..FGRFNERASFGDNVNLKTTILSRFDMI.FMIRD.KHDAKRDKEIVK-----HYYG--...------.-.--.-.-.-.-.--...........---YSIVKRKV---.DnLSQA..--.-.--.-..........--.---.-------FKEYIAYC.KAYCIP..R....LTVNA.SNKLSNYFVSIRQKVR-.ENK.LEN.DNDEGIPITVRQLEAIIRISEALAKMTMSDIADENHVDEAIRLFELSTM
Q8I5T4_PLAF7/352-678 ERNELTLL.AAEH..NIHEKIFKSIAPELYG..MDE.VKKACACLLFGGTR.K..RIGE.ETK..IRGDINMLMLGDPS..-VAKSQILKFV.N.RCAPVSVYTSGKGSSAAGL.TAAVMRDSQGV-...FSLEGGAMVLADGGVVCIDEFDKMRDDDVVAIHEAMEQQTISISKAG.ITTM.LNTRCSVIAAANPS..FGSYDDSQDTTYQHDFKTTILSRFDII.FLLRN.KQDVEKDTLLCNHIVALHASK--...------.-.--.-.-.-.-.--...........---HKSQEG-----.-.----..--.-.--.-..........--.---.-EIPLSKLTRYIQYA.KREIAP..L....LSKEA.RDSLRNFYVQTRAEYRG.---.-DRrSVTKKIPITLRQLESLIRLAESFAKMELSQFATDKHVQMSIDLFSASTA
Q7QSR9_GIALA/322-652 DIPKFHAF.KNQP..NVISVIESLIAPQIEG..MED.AKRAIACLLFGGTN.K..YTQE.LIR..LRGNINVLLISDPG..-LGKSELLLEA.S.RLAPIGIYTSGKSTSAVGL.TAGVMRDKATSE...FFLEGGALVLADKGIVCIDELDKMNETDRVALHEAMEQGSISISKAG.ISTT.LNARTSILAAANPT..LGRFDDFQKAADQIDFSVTILTRFDLV.FMLKD.KQSPERDAMIVN-------KIA-...---RIAaGeRP.-.-.-.-.--...........ASVASHQEQNP---.-.----..--.-.--.-..........--.---.-MFTQSFLKKYIAYA.QATCTP..K....LDQSS.LEILKAAYIRYRADAL-.---.-KN.--SSAIPITVRQLEALIRLSESFAKMRLSPVVTVEDVEYAIDIFQKSTA
Q8PVX1_METMA/263-609 EEEQILEL.SRDP..AIYEKIISSIAPSIYG..YED.IKEALALQLFSGVV.K..NLPD.GSR..TRGDIHMMLVGDPG..-IAKSQLLRYV.V.KLSPRGVFASGRSASASGL.TAAAVKDDMNDG..rWTIEGGALVMADMGVAAVDEMDKMRTEDKSALHEAMEQQTISIAKAG.IIAT.LKSRCALLGAANPK..YGRFDRYEGLADQINMPPALLSRFDLI.FVLLD.TPNHSLDSRIANHILQSHYAGEL..sEQRQKLpGsTI.-.-.-.-.--...........--SEEFVDAEM---.-.----..--.-.--.-..........--.EIIePVIAPEFMRKYIAFA.RKNVYP..V....MEEDT.RHHLINFYTDLRRSGE-.---.-GK.--NTPVPVTARQLEALVRLSEASARVRLSNIVTLEDAKRTIRIVMNCLK
O27798_METTH/256-576 DEEKIKEL.AGDP..NIYEKIIRSTAPSIHG..YRE.VKEAIALQLFGGTG.K..ELDD.KTR..LRGDIHILIVGDPG..-IGKSQMLKYV.S.KLAPRGIYTSGKGTSGVGL.TAAAVRDEFGG-...WSLEAGALVLGDKGNVCVDELDKMREEDRSAIHEALEQQTISIAKAG.IMAT.LNSRCSVLAAANPK..FGRFDSYKSIAEQIDLPSTILSRFDLI.FVVED.KPDEEKDRELARHILKTHK----...------.-.--.-.-.-.-.--...........---EDHMPF-----.-.----..--.-.--.-..........--.---.-EIDPELLRKYIAYA.RKNVRP..V....LTDEA.MQVLEDFYVSMRASAA-.---.---.DEDSPVPITARQLEALVRLSEASAKIKLKEHVEAEDARKAIKLSQACLK
O29733_ARCFU/151-494 DRELIMQL.AASD..DIYEKIVKSIAPSIYG..HED.VKLAIALQLFGGVP.K..KLPD.GTE..IRGDIHILLVGDPG..-VAKSQLLKYV.H.RIAPRSVYTTGKGTTTAGL.TATAVRDEVDGR...WTLEAGALVLADKGIALVDEIDKMRKEDTSALHEALEQQTISVAKAG.INAI.LKARCALLGAANPK..YGRFEKFTPVPEQIEMSPTLLSRFDLI.FVLKD.EPDEEKDKRLVEHILYSHQLGE-...------.-.--.-.-.MtEkAK..........nVAAEYDEEF-I---.-.----..RQrSeRIvP..........--.---.-EIDPDLLRKYIAYA.RKTVYP..V....LTDEA.KEKIKEFYLSLRSRV--.---.---.KENSPVPITARQLESIVRLAEASARVRLSDRVEPEDVDRVIEIMMRSLR
Q975E0_SULTO/138-460 DEKKIREL.SRDP..WIREKIISSIAPSIYG..HWE.IKEAIALALFGGVP.K..IMED.GTR..VRGDIHVLIIGDPG..-TAKSQILQFA.A.RVAPRAVYTTGKGSTAAGL.TATVTRDKNTGD...YYLEAGALVLADGGVAVIDEIDKMREEDRVAIHEAMEQQTVSIAKAG.IVAK.LNARATVVAAGNPK..LGRYIAERGIAENINLPPTILSRFDLI.FILID.KPG-VEDQLLASHILNVHAGKT-...------.-.--.-.-.-.-.--...........------KSTEI---.-.----..--.-.--.-..........--.---.--IDVDLLKKYIAYA.RKNVFP..K....LSDEA.KSLLQDFFVEMRKKS--.---.--SeSPDSPIIITPRQLEALIRISEAYARMALKNEVTREDAERAINIMRIFLE
Q9YFR1_AERPE/280-607 DEEKILQL.SRDP..WIKEKIIASIAPTIYG..HWD.LKEAIALLLFGGVP.K..QRPD.GTR..TRGDIHVLFVGDPG..-VAKSQLLQST.A.QVAPRVVYTTGKGSTAAGL.TAAVLRDPRTGE...YFLEAGALVLADGGIAVIDEFDKMSKEDRGVIHEAMEQQTVSIAKAG.IKAT.LSARASLLAAGNPK..FGYYDPSRSFVDNVDLPAPIISRFDLI.FVVRD.VIERSRDEMLASYVLETHTN---...------.-.--.-.-.-.-.--...........-----VELFKP---.-.----..--.-.--.-..........--.---.-EIDPDLLRKYIAFA.RKHVKP..R....LTPQA.KKLLKDFYVEMRSSAL-.-HHsSQE.-GAKPVPITTRQLEALIRLTEAHARMSLKQEATEEDAIAAIRIMTSVLQ
Q8ZY88_PYRAE/266-590 DEQKILEI.SRRP..DVRELIIRSIAPSIYG..YEE.VKEAVACLLFGGNE.I..VYPD.GVR..VRGDINILLIGDPG..-TAKSQLLKFV.A.KIAPRAVYTTGKGSSAAGL.TAAVVRDKLTGE...FYLEAGALVLADKGVAVIDEIDKMDAKDRVALHEAMEQNTVSISKAG.IVAT.LNARAAVLAAANPA..FGRYLPNRTVAENIDLPVSLLSRFDLI.FVIRD.EPREEFDSAVAGHILDLHSGK--...------.-.--.-.-.-.-.--...........----TPEAFRD---.-.----..--.-.--.-..........--.---.-VLRPDFLRKYIMYA.RRYVRP..I....LSEEA.KERIKAFYLEMRKRY--.---.-QGpGTA--IAITARQLEALIRLTTAEAKMRLSPIAAAEDAERAIRLYLAFLK
Q979U9_THEVO/274-612 DKQKIIEI.SKRP..NVIDVIAKSIAPTIHG..LDM.IKKALALQMFGGVR.K..TMKD.GTT..MRGDIHILMVGDPG..-TAKSQLLKYM.A.EVSPRGIFTFGRGSSAAGL.TAAAVRDEFGEG..rWTLEAGALVLADNGFVAIDELDKMDEHDTAAMHEAMEQQTVTISKAG.IMAT.LRARASVLAAANPK..FGRYDLNRNLAEQINFPLPLLSRFDVI.FKMVD.QPNKDTDSQLAEHVLKAHRLGE-...------.-.--.-.-.-.-.--...........--IYKSMEKNDIEI.-.----..-DvPdEAkYe........pD-.---.--IDKDLLRKYVAYA.KNNVFP..R....LSDEA.IAILQDQYVRTR-----.---.TGS.--RDSIPITVRQLESTIRLAEAAARARLSTIVTVEDAMLAKKIVDYYLT
Q8TJF6_METAC/263-611 DEKKILTL.ARDP..AVYDKVISSIAPLIYG..MDD.VKEATALQLFSGVP.K..NAPD.GSY..LRGDIHLLCVGDPS..K-GKTKLMKSS.Q.ARSPRAVFTSRKATTAGGL.TAIVTKDEKFGEg.rWAVEGGALVMADKGVAYVDEADKMRQGDRDALHEAMEQQEINLAKAG.IIAT.LKTRTAVFMSANPK..YGKFDTYEGLAEQINMPPSLLSRFDLI.FVLLD.TPNAVEDARISEHVLGTHTA---...---GEMrQqREtVsDsAfStEE...........-LAEASTHVRP---.-.----..--.-.--.-..........--.---.-EIPPDLFRKHVAYA.RRNIFP..V....LTTEA.RDHIHHFYLDLRKTG--.---.-QS.SKIKSIPITTRQEEATVRLAEASARVRLSQGVTLDDAKRATRLMLNCLR
Q871F1_NEUCR/476-832 DEHEIRRL.SRDP..HIVDKIINSVAPSIYG..HTD.IKTAVALSLFGGVA.K..QVGA.-HH..IRGDINVLLLGDPG..-TAKSQVLKYA.E.KTAHRAVFATGQGASAVGL.TASVRRDPLTSE...WTLEGGALVLADKGTCLIDEFDKMNDQDRTSIHEAMEQQTISISKAG.IVTT.LQARCGIIAAANPI..GGRYNSTIPFSANVELTEPILSRFDIL.CVVRD.TVEPEEDERLARFIVGSHSRSHP..lMNNNTQdAsGGdS.MeVeHdTQ...........AAAETQQTGEHGRK.-.----..--.-.--.-..........--.--KeGEIPQELLRKYILYA.RERCQP..K....LYHMD.EDKVARLFADMRR----.ESLaTGA.-----YPITVRHLEAIIRISEAFCRMRLSEYCSAQDIDRAIAVTVESFV
MCM2_YEAST/480-846 EEREFRKI.SRDR..GIIDKIISSMAPSIYG..HRD.IKTAVACSLFGGVP.K..NVNG.KHS..IRGDINVLLLGDPG..-TAKSQILKYV.E.KTAHRAVFATGQGASAVGL.TASVRKDPITKE...WTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAG.IVTT.LQARCSIIAAANPN..GGRYNSTLPLAQNVSLTEPILSRFDIL.CVVRD.LVDEEADERLATFVVDSHVRSHP..eNDEDRE.GeEL.-.-.-.-.--...........KNNGESAIEQGEDEiNeQLNA..RQrRlQRqR..........-KkEEEiSPIPQELLMKYIHYA.RTKIYP..K....LHQMD.MDKVSRVYADLRR----.ESIsTGS.-----FPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFV
MCM2_SCHPO/471-810 EEREIRAL.AKSP..DIHNRIIASMAPSIYG..HRS.IKTAIAAALFGGVP.K..NING.KHK..IRGDINVLLLGDPG..-TAKSQFLKYV.E.KTAHRAVFATGQGASAVGL.TASVRKDPITNE...WTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAG.IVTT.LQARCTIIAAANPI..GGRYNTTIPFNQNVELTEPILSRFDIL.QVVKD.TVNPEIDEQLANFVVSSHIRSHP..aFDPN--.MdVL.-.-.-.-.--...........---KKVPTETG---.-.----..--.-.--.-..........--.-IDaKPIPQDLLRKYIHFA.REKVFP..R....LQQMD.EEKISRLYSDMRR----.ESLaTGS.-----YPITVRHLESAIRLSEAFAKMQLSEFVRPSHIDKAIQVIIDSFV
Q8SS42_ENCCU/362-688 DVREIKKM.GRHP..EIKRIVINSIAPSVYG..HAE.VKRAIALAMLGGVA.R..ESTS.-HR..IRGDINVLLLGDPG..-MAKSQFLRYV.E.STSHRAVLATGQGASSVGL.TASVRKDPVVKE...WTLEGGALVLADKGICLIDEFDKMNEHDRTSIHEAMEQQSISISKAG.IVAT.LHARCSVIAAANPM..RGRYNGSLTFAQNVNLSDPIISRFDIL.CVVKD.AIDAGEDEKTAKFVIESHEGGE-...------.-.--.-.-.-.-.--...........---EKPDGFDP---.KrMMMG..--.-.--.-..........--.---.----HELLRKYILYA.RTNVVP..A....FNDVD.MEKISSLYLELRK----.ESL.PSG.-----LPVTVRHVESIVRISEAFAKMRLSRVVSVEDIDEAISVVLDSFM
Q9BI22_DUGJA/443-793 DIVNIQNL.AKDE..RLFDRILRSIAPSIYG..HEN.IKRAIALSLFGGVA.K..TKGQ.KLR..GRGDINVLICGDPG..-TAKSQFLKFV.E.QLAPRCVFTTGQGASAVGL.TAYVSRNPTSKE...WTLEAGALVLADKGVCLIDEFDKMNGQDRTSIHEAMEQQTISISKAG.IVTS.LQARSTIIAAANPI..AGRYDTSRNFSDNVDLTSPILSRFDIL.CVVRD.IVDPIQDSMLAKYVIGSHMRHHG...RLSEEEkKeVVkR.LeAlGaMV..........nTSDSEAGDLQA---.-.----..--.-.--.-..........--.---.--IPLELLQKYIIYA.RQRVSP..R....LSKTN.EGKLCEVYVELRK----.ASKeNGG.-----IDVTVRYFESMIRLSEAHAKLHFREVVNEEDVNMAIRVLLESFI
Q9XXI9_CAEEL/435-777 DIKAIREL.SQDP..NISQRVFSSIAPSIYG..HDD.VKRAIALALFRGEA.K..NPGA.KHR..LRGDINVLLCGDPG..-TAKSQFLRYA.A.HIAPRSVLTTGQGASAVGL.TAYVQRHPVTRE...WTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAG.IVTS.LHARCTVIAASNPI..GGRYNPTRTFAENVDLTEPILSRFDVL.CVIRD.SVDSVEDERLAKFVVGNHRTHHP..dAKKIVKeGdEL.-.-.-.-.--...........--EEDQMDERTGVR.-.----..--.-.--.-..........--.---.-LIPQDLLRKYIIYA.REKCHP..T....LPEQH.SEKFSNIFAQMRK----.ESMaTGS.-----VAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIRVMLESFV
MCM2_DROME/445-780 DIATIQKL.SKDP..RIVERVVASMAPSIYG..HDY.IKRALALALFGGES.K..NPGE.KHK..VRGDINLLICGDPG..-TAKSQFLKYT.E.KVAPRAVFTTGQGASAVGL.TAYVRRNPVSRE...WTLEAGALVLADQGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAG.IVTS.LQARCTVIAAANPI..GGRYDPSMTFSENVNLSEPILSRFDVL.CVVKD.EFDPMQDQQLAKFVVHSHMKHHP..sEE----.-.--.-.-.-.-.--...........--EQPELEEPQLKTvD.----..--.-.--.-..........--.---.-EIPQDLLRQYIVYA.KENIRP..K....LTNID.EDKIAKMYAQLRQ----.ESFaTGS.-----LPITVRHIESVIRMSEAHARMHLRENVMEADVSMAIRMMLESFI
Q96275_ARATH/41-383 DKTQIEEL.SKDP..RIVERIIKSIAPSIYG..HED.IKTALALAMFGGQE.K..NIKG.KHR..LRGDINVLLLGDPG..-TAKSQFLKYV.E.KTGQRAVYTTGKGASAVGL.TAAVHKDPVTRE...WTLEGGALVLADRGICLIDEFDKMNDQDRVSIHEAMEQQSISISKAG.IVTS.LQARCSVIAAANPV..GGRYDSSKSFAQNVELTDPILSRFDIL.CVVKD.VVDPVTDEMLAEFVVNSHFKSQPkggKMEDSDpEdGI.-.-.-.-.--...........--QGSSGSTDP---.-.----..--.-.--.-..........--.---.EVLPQNLLKKYLTYS.KLYVFP..K....LGELD.AKKLETVYANLRR----.ESMnGQG.-----VSIATRHLESMIRMSEAHARMHLRQYVTEEDVNMAIRVLLDSFI
Q9U446_ENTHI/523-861 EEQEIRRL.ANNP..QIFQIIINSIAPAIYG..HDA.SKAAIALALFGGEQ.R..VLVD.KGNhrTRGDINVLLLGDPG..-TAKSQLLKYS.Q.KLAPRAVFTTGRGSTAVGL.TAAVKKDSMNGE...WALEGGALVLADEGVCLIDEFDKMDDQDRTSIHEAMEQQSISISKAG.IVTS.LKARCSVIAAANPK..TGKYNPNKNLNQNVNLTEPIISRFDLI.MIVRD.VVDYVKVYKLAQFVVESHSINHP..eASQKR-.-.--.-.-.-.-.--...........ESIAPIVNKTN---.-.----..--.-.--.-..........--.---.-IISHVLLKKYIAYA.RQNCHP..K....WSGTVgSQMIQQAYIEMRK----.---.--CcDKYHTGQVTARQIEAINRLSEAHAKIHLRGVVTTEDVKIALKITLKSFI
Q9U1E0_LEIMA/317-646 QVEDIRDY.PDRE..AVIEKLTRSIAPEIWG..MED.VKKALLCQLVGGSS.-..-IAN.GIR..IRSDINILFMGDPG..-VAKSQLLKWI.A.SVAPRSVFTTGKGSSGVGL.TAAVTHDTHTGE...VMLEGGALVLSDKGVCCIDEFDKMDDSDRTALHEVMEQQMVSIAKAG.IITS.LNARTSILAAANPK..FGRWKRNATPTENVNLPPALLSRFDLL.WLLLD.ESSRERDAELSMHVTHVHLHG--...------.-.--.-.VaPgTvAD...........--DGVRGTTTEY--.-.----..--.-.--.-..........--.---.--FGRDFLRAYVGEV.K-RIHP..Y....VDPGA.AKAISDIYCEMRAQSA-.---.---.--RHSNVVTARTLLSLIRLSQACARLRFSERVLEEDVREAGRLLDCSKA
O16297_CAEEL/328-652 QSAELEVL.RRKG..DNYETLAASIAPEIFG..HVD.VKKCLLMALVGGND.N..SS-N.GMK..IRGCINVLMMGDPG..-VAKSQLLGYV.N.RLAPRSQYTTGRGSSGVGL.TAAVMKDPVTGE...MSLEGGALVLADGGICCIDEFDKMMDHDRTAIHEVMEQQTISIAKAG.IMTT.LNARTAIIAAANPA..YGRYNPNRSIEQNVDLPAALLSRFDLI.LLMQD.KADRENDKILAEHITYVHQHGC-...------.-.--.-.-.-.-.--...........---HPNREKKD---.-.----..--.-.--.-..........--.---.-LISLETLREYISLC.K-TYTP..T....VDPAL.RERIVEAYVEMRRDAR-.---.---.YSSDPTFVSPRMILGIVRMATARAKLRLSTIVDESDVEEALRLMQFAKD
Q7Q6K1_ANOGA/318-640 TQEELDEL.AKD-..DFYTRIASSLAPEIYG..HLD.VKKALLLLLVGGVD.-..RSPD.GMK..IRGNINICLMGDPG..-VAKSQLLGYI.D.RLAVRSQYTTGRGSSGVGL.TAAVMKDPLTGE...MVLEGGALVLADQGVCCIDEFDKMADEDRVSIHEVMEQQTISIAKAG.IMTC.LNARVSILAAANPA..YGRYNPRRTIEQNIQLPAALLSRFDLL.WLIQD.KADRDNDLRLAKHITYVHSHGK-...------.-.--.-.-.-.-.--...........---QPPSRIKT---.-.----..--.-.--.-..........--.---.--LDMTLIRRYIALC.K-RKIP..V....ITPEL.TDYIVNAYVELRREAR-.---.---.NSRDMTFTSARNLLGILRLSTALARLRLADTVEKDDVKEALRLLAMSKD
CDC47_YEAST/397-725 VEERVMEL.ITSG..DVYNRLAKSIAPEIYG..NLD.VKKALLLLLVGGVD.K..RVGD.GMK..IRGDINVCLMGDPG..-VAKSQLLKAI.C.KISPRGVYTTGKGSSGVGL.TAAVMKDPVTDE...MILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAV.INTN.PGARTSILAAANPL..YGRINPRLSPLDNINLPAALLSRFDIL.FLMLD.IPSRDDDEKLAEHVTYVHMHNK-...------.-.--.-.-.-.-.--...........---QPDLDFTP---.-.----..--.-.--.-..........--.---.--VEPSKMREYIAYA.K-TKRP..V....MSEAV.NDYVVQAYIRLRQDSKR.---.-EMdSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKE
PROL_ARATH/313-638 EEEQIARL.AEDG..DIYNKLSRSLAPEIYG..HED.IKKALLLLLVGAPH.R..QLKD.GMK..IRGDVHICLMGDPG..-VAKSQLLKHI.I.NVAPRGVYTTGKGSSGVGL.TAAVMRDQVTNE...MVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAG.ITTS.LNARTAVLAAANPA..WGRYDLRRTPAENINLPPALLSRFDLL.WLILD.RADMDSDLELAKHVLHVHQTEE-...------.-.--.-.-.-.-.--...........---SPALGFEP---.-.----..--.-.--.-..........--.---.--LEPNILRAYISAA.R-RLSP..Y....VPAEL.EEYIATAYSSIRQEE--.---.--AkSNTPHSYTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQMSKI
Q7RJM3_PLAYO/402-752 IMEEVQKL.KSSP..NLYERLAYNIGPEIYG..HED.VKKALLLQLIGGCT.K..KKKD.GGL..IRGDIHILLMGDPG..-VAKSQLMKKV.C.LIASRSIYTTGKGSSSVGL.TAAVLKDPNTGE...TTLEGGALVLADKGICCIDEFDKMDEFDRSAIYEVMEQQTVSIAKAG.-HCSnMPARSSVLAAANPI..NGRYDCKKSVMLNMNLPAALLTRFDLQ.FLLLD.ISDRDKDKRLAEHVLNILK--C-...------.-.--.-.-.-.-.--...........---VDSTDDKK---.-.---K.kRKkKkTGlNnkddndddgyE-.---.-EIDKTVLRAFIQLA.K-RKQP..T....ISPEL.IPKITQWYVSSRQLESQqERY.---.NDTRINYTTPRALLAILRISQALARVRDSDIIETPDFEEAIRLTEQSKA
Q8RYQ2_ORYSA/440-767 KVEKLKEL.SKLP..DIYDRLTRSLAPNIWE..LDD.VKRGLLCQLFGGNA.L..RLPS.GAS..FRGDINILLVGDPG..-TSKSQLLQYM.H.KLSPRGIYTSGRGSSAVGL.TAYVTKDPETGE...TVLESGALVLSDKGVCCIDEFDKMSDNARSMLHEVMEQQTVSIAKAG.IIAS.LNARTSVLACANPT..ESRYNPRLSVIDNIHLPPTLLSRFDLI.YLILD.KADEQTDRRLAKHIVSLHFE---...------.-.--.-.-.-.-.--...........---NPNIEELE---.-.----..--.-.--.-..........--.---.-VLDLPTLVAYISYA.RKHIQP..Q....LSDEA.AEELTRGYVEMRKRGN-.---.-SPgSRKKVITATARQIESLIRLSEALARMRFSEMVEVQDVVEAFRLLEVAMQ
Q86IF1_DICDI/469-792 KEREIIEL.SKKP..DIYDIVTKSIAPNIWE..LED.IKKGILCQLFGGSK.K..SYQDyGGK..FRGDINILLCGDPG..-TSKSQLLSYV.H.KIAPRGIYTSGKGSSAVGL.TAYITKDPDTKE...TVLESGALVLSDKGVCCIDEFDKMNDQTRSILHEVMEQQTVSIAKAG.IICT.LNARTSILASANPS..GSRYMPKLSVVENIQLPPTLLSRFDLI.YLVLD.KANERSDRQLARHLVSMYWDE--...------.-.--.-.-.-.-.--...........---TPVSHF-----.-.----..--.-.--.-..........--.---.-TIPKETLTNYIQYA.RKHINP..K....LTDDS.AKCLVQGYLEMRSMG--.---.---.SSKKTISATPRQLESLIRIAEAHARIRFSEFVEPLDVEEAIRLIKVALQ
MCM4_SCHPO/480-811 EVEKIQQV.SKRD..DIYDILSRSLAPSIYE..MDD.VKKGLLLQLFGGTN.K..SFHK.GASprYRGDINILMCGDPS..-TSKSQILKYV.H.KIAPRGVYTSGKGSSAVGL.TAYITRDQDTKQ...LVLESGALVLSDGGICCIDEFDKMSDATRSILHEVMEQQTVTVAKAG.IITT.LNARTSILASANPI..GSKYNPDLPVTKNIDLPPTLLSRFDLV.YLILD.RVDETLDRKLANHIVSMYMEDT-...------.-.--.-.-.-.-.--...........---PEHATDME---.-.----..--.-.--.-..........--.---.-VFSVEFLTSYITYA.RNNINP..V....ISEEA.AKELVNAYVGMRKLGE-.---.-DVrASEKRITATTRQLESMIRLSEAHAKMHLRNVVEVGDVLEAARLIKTAIK
CDC54_YEAST/505-834 DLAKIREV.AARE..DLYSLLARSIAPSIYE..LED.VKKGILLQLFGGTN.K..TFTK.GGR..YRGDINILLCGDPS..-TSKSQILQYV.H.KITPRGVYTSGKGSSAVGL.TAYITRDVDTKQ...LVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAG.IITT.LNARSSILASANPI..GSRYNPNLPVTENIDLPPPLLSRFDLV.YLVLD.KVDEKNDRELAKHLTNLYLEDK-...------.-.--.-.-.-.-.--...........---PEHISQDD---.-.----..--.-.--.-..........--.---.-VLPVEFLTMYISYA.KEHIHP..I....ITEAA.KTELVRAYVGMRKMGD-.---.-DSrSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIK
Q7SHS5_NEUCR/580-912 EEERIKET.AARP..DIYDLLSRSLAPSIYE..MDD.VKKGILLQLFGGTN.K..TFEK.GGSpkYRGDINVLLCGDPS..-TSKSQLLSYV.H.RIAPRGVYTSGKGSSAVGL.TAYVTRDPESRQ...LVLESGALVLSDGGVCCIDEFDKMNESTRSVLHEVMEQQTVSVAKAG.IITT.LNARTSILASANPI..GSRYNPDLSVPQNIDLPPTLLSRFDLV.YLILD.RVDEKNDQRLARHLLSMYLEDK-...------.-.--.-.-.-.-.--...........---PESAQQAN---.-.----..--.-.--.-..........--.---.DVLPVEFLTSYISYA.RSHIHP..A....LTPEA.GRELVDAYVEMRKLGQ-.---.-DVrAAEKRITATTRQLESMIRLAEAHAKMRLSQTVTRDDVREAVRLIKSALK
Q95XQ8_CAEEL/404-730 RIQQIIEL.SKRP..DIMDALAQSIAPSIYE..HDD.VKRGLLCLLFGGTR.KddETTN.KTK..LRSEINILLCGDPG..-TSKSQMLQYV.Y.RLLPRSQYTSGKGSSAVGL.TASVSRDADTKQ...LVLQTGALVLADNGVCCIDEFDKMNESARSVLHEVMEQQTLSIAKAG.IICQ.LNARASVLAAANPV..DSKWNRNKTIVENITLPHTLLSRFDLI.FLIVD.AQDEMQDRRLGNHLVSLYFEND-...------.-.--.-.-.-.-.--...........-GNQEKTEH-----.-.----..--.-.--.-..........--.---.--VDMNLLRDYIAYA.KANIHP..K....LSEEA.SQFIIEKYLFMRKAG--.---.---.AQHGQITAYPRQLESLIRLSEAHAKIRLSQEVSVDDVEKAFTLWREALK
O42589_XENLA/440-765 RVAVLKEL.AAKP..DIYERLAAALAPSIYE..HED.IKKGILLQLFGGTR.K..DFSH.TGRgkFRAEVNILLCGDPG..-TSKSQLLQYV.Y.NLVPRGQYTSGKGSSAVGL.TAYVMKDPETRQ...LVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAG.IICQ.LNARTSVLAAANPV..ESQWNPKKTTIENIQLPHTLLSRFDLI.FLMLD.PQDETYDRRLAHHLVVLYYQS--...------.-.--.-.-.-.-.--...........---EEQLKEEH---.-.----..--.-.--.-..........--.---.--LDMAVLKDYIAYA.RTYVNP..R....LGEEA.SQALIEAYVDMRKIG--.---.---.SGRGMVSAYPRQLESLIRLSEAHAKVRFSSKVETIDVEEAKRLHREALK
MCM4_DROME/447-772 RVELLQLL.AKKP..DIYDRLARAIAPSIYE..NDD.IKKGILLQLFGGTK.K..KHAT.LGRqnFRSEIHLLLCGDPG..-TSKSQMLQYV.F.NLVPRSQYTSGRGSSAVGL.TAYVTKDPETRQ...LVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAG.IICQ.LNARTSILAAANPA..ESQWNKRKNIIDNVQLPHTLLSRFDLI.FLVLD.PQDEIFDKRLASHLVSLYY----...------.-.--.-.-.-.-.--...........VTRHEEEDT-----.-.----..--.-.--.-..........--.---.-MFDMSVLRDYIAYA.REHLSP..T....LSDEA.QQRLIQAYVDMRKVG--.---.---.AGRGQISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREALK
Q8SSE5_ENCCU/304-622 PIDKIDEL.RKRP..DVYEILANSVAPSVCG..MED.TKKALVLQLFGGVR.K..ELGS.-SR..LRGDINILLAGDPG..-ISKSQLLSFI.H.RTSERGMYTSGRGSSAVGL.TASVAKDPDTGQ...FILESGALVLSDNGICCIDEFDKMSDSTRSVLHEVMEQQTVSVAKAG.IITT.LNARCSILASCNPI..ESKYNPRKSIVENINLPPTLLSRFDVV.CLMID.RCDEFYDRTIGDHIVSLY-----...------.-.--.-.-.-.-.--...........---SEETQRKEY--.-.----..--.-.--.-..........--.---.--IDADLLKAYVREA.R-RIVP..R....LTPES.MKMLTQSYVDLRQMDN-.---.-GK.----TITATTRQLESLIRLSEAHARMRFSNAVEAKDVREAVRIIRESLL
Q7R0J9_GIALA/381-716 FPDMIPETdSGSD..KRFLKLINSIAPSIFGpaYSD.IKTGLLLQCFGGVQ.K..---D.--S..YRGQIHVLLVGDPG..-LAKSKLLQYV.A.KISPRSVYTSGKGSSQAGL.TATVSRHPETHE...FYLDPGALLLSDGGICCLDEFDKSSEDVRSSLHEVMEHGQLSIAKAG.ILAT.LSAKTSILAAANPI..DSCYNPKRTVVQNLNLPPSLLSRFDLI.YLLLDnRHDTEADRALASWLVSMYISS--...--GQAEhSgHL.-.-.-.-.--...........SSKNTAAATPD---.-.----..--.-.--.-..........--.---.-AWDPQVLRQYIYFA.Q-KLSP..V....LSKSA.QDALLLSYNQLRS----.---.-GSySASGRITATPRQLMSLIRLAEARARIRFSNFVTANDILEVSRLMTRAMH
Q8H1A3_PEA/330-651 ELDEVQRM.RNTP..DFFTKLVESVAPTIFG..HQD.IKRAILLMLMSGVH.K..STHE.GIS..LRGDINVCIVGDPKlcKVSISQVSSSI.V.---PRSVYTSGKSSSAAGL.TATVAKEPETGE...FCIEAGALMLADNGICCIDEFDKMDIRDQVAIHEAMEQQTISITKAG.IQAT.LNARTFHSCCCQPL..E---DDDKLPLKTCGSSTGYTLRFDLV.YIMID.DPDDNTDYHIASHIVRVHQKR--...------.-.--.-.-.-.-.--...........---EDALAP-----.-.----..--.-.--.-..........--.---.-TFTTAELKRYIAYA.K-TLKP..K....LTSDA.RKLLVDSYVALRRAD--.---.-TNpGSRVAYRMTVRQLEALIRLSEAIARCHLDNQVQPRHVRLAVKLLQTSII
Q86B14_DICDI/407-731 EKDSLKKM.IKSK..KIYQNLVNSICPSIFG..HEE.IKRGVLLMLFGGVH.K..KTPE.KIR..LRGDINVCIVGDPS..-TSKSTFLKYL.V.SFLPRTVYTSGKASSAAGL.TATVVKDQESGD...FNIEAGALMLADNGICCIDEFDKMEPGDQVAIHEAMEQQTISIAKAG.IHAS.LNARTSILAAANPI..GGRYDRNKTLKQNLNIGGPLMSRFDLF.FVVLD.ECNPESDHRIAEHIVLTHQKR--...------.-.--.-.-.-.-.--...........-----EKAFNA---.-.----..--.-.--.-..........--.---.-PFSATEIKNYIKYT.K-FICP..T....IPDES.VQLLVGHYDRLRQMD--.---.-TSgSKTPAYRITVRQLESLVRLSESLARLHLDTKVLPKYVNEAARLLEKSIV
MCM6_SCHPO/413-737 EIDDLRAM.VHSD..HIYSRLTNSLAPSVYG..HEI.IKKGILLQLMGGVH.K..LTPE.GIN..LRGDLNICIVGDPS..-TSKSQFLKYV.C.NFLPRAIYTSGKASSAAGL.TAAVVKDEETGD...FTIEAGALMLADNGICAIDEFDKMDLSDQVAIHEAMEQQTISIAKAG.IQAT.LNARTSILAAANPI..GGRYNRKTTLRNNINMSAPIMSRFDLF.FVVLD.ECNESVDRHLAKHIVDIHRLR--...------.-.--.-.-.-.-.--...........---DDAMQP-----.-.----..--.-.--.-..........--.---.-EFSTEQLQRYIRYA.R-TFKP..K....LNTES.CAEIVKKYKQLRMDDA-.---.-QG.AGKNSYRITVRQLESMIRLSEAIARANCVDDITPAFVNEAYSLLRQSII
MCM6_YEAST/512-836 EINELKEM.VKDE..HIYDKLVRSIAPAVFG..HEA.VKKGILLQMLGGVH.K..STVE.GIK..LRGDINICVVGDPS..-TSKSQFLKYV.V.GFAPRSVYTSGKASSAAGL.TAAVVRDEEGGD...YTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAG.IHAT.LNARTSILAAANPV..GGRYNRKLSLRGNLNMTAPIMSRFDLF.FVILD.DCNEKIDTELASHIVDLHMKR--...------.-.--.-.-.-.-.--...........---DEAIEP-----.-.----..--.-.--.-..........--.---.-PFSAEQLRRYIKYA.R-TFKP..I....LTKEA.RSYLVEKYKELRKDDA-.---.-QG.FSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQSII
MCM6_CAEEL/333-660 DRATLKKM.SDDK..KIEKNIVDSLFPNIYG..NHE.VKLGVLLMLLGGVAkK..SRDE.GTS..LRGDINVCLVGDPS..-TAKSQVLKAV.E.EFSPRAIYTSGKASSAAGL.TAAVVKDEESFE...FVIEAGALMLADNGVCCIDEFDKMDLKDQVAIHEAMEQQTISITKAG.VKAT.LNARASILAAANPV..NGRYDRSRPLKYNVQMSAPIMSRFDLF.FVLVD.ECNEVTDYAIARRILDNHRAI--...------.-.--.-.-.-.-.--...........---SEHTERDS---.-.----..--.-.--.-..........--.---.-VYKIDDIKKYIAFA.R-CFKP..K....ISDKA.AETLVREYKKLRMSD--.---.-SNnAATSSWRITVRQLESLVRLSEALARLHCGKEVLVEHVEKAAELLNKSIV
Q960E3_DROME/56-380 EWHKIYEM.SKDR..NLYQNLISSLFPSIYG..NDE.VKRGILLQQFGGVA.K..TTTE.KTS..LRGDINVCIVGDPS..-TAKSQFLKQV.S.DFSPRAIYTSGKASSAAGL.TAAVVRDEESFD...FVIEAGALMLADNGICCIDEFDKMDQRDQVAIHEAMEQQTISIARAG.VRAT.LNARTSILAAANPI..NGRYDRSKSLQQNIQLSAPIMSRFDLF.FILVD.ECNEVVDYAIARKIVDLHSNI--...------.-.--.-.-.-.-.--...........---EESVER-----.-.----..--.-.--.-..........--.---.-AYTREEVLRYVTFA.R-QFKP..V....ISQEA.GHMLVENYGHLRQRD--.---.TGT.SGRSTWRITVRQLESMIRLSEAMAKLECSNRVLERHVKEAFRLLNKSII
MCM6_RAT/19-343 EWEKVFEM.SQDQ..NLYHNLCTSLFPTIHG..NDE.VKRGVLLMLFGGVP.K..TTGE.GTS..LRGDINVCIVGDPS..-TAKSQFLKHV.D.EFSPRAVYTSGKASSASGL.TAAVVRDEESHE...FVIEAGALMLADNGVCCIDEFDKMDMRDQVAIHEAMEQQTISITKAG.VKAT.LNARTSILAAANPV..SGHYDRSKSLKQNINLSAPIMSRFDLF.FILVD.ECNEVTDYAIARRIVDLHSRI--...------.-.--.-.-.-.-.--...........---EESIDR-----.-.----..--.-.--.-..........--.---.-VYSLDDIRRYLLFA.R-QFKP..K....ISKES.EDFIVEQYKRLRQRD--.---.-GSgITKSSWRITVRQLESMIRLSESMARMHCCDEVQPKHVKEAFRLLNKSII
Q8SRX5_ENCCU/300-624 ELATISEM.RSTP..DLYYKLSQSMFPSIHG..HYS.IKNAILLLLVGGVG.K..RAEG.GTR..LRGDINMLLVGDPG..-TAKSQFLKQA.S.AFLPRSVYTSGKSSSAAGL.TASVVKDGETGE...FTIEAGALMLSDTGVCCIDEFDKMNVKDQVSIHEAMEQQTITISKAG.INAT.LNARSSILAAANPI..KGRYDKKKTLRQNINLSAPVMSRFDLY.FVLID.DADPENDRNVATHVLNSHAS---...------.-.--.-.-.-.-.--...........--VTDSGVLASY--.-.----..--.-.--.-..........--.---.--FTREQVKLYLRYA.R-KKTP..R....MTAEA.KEMLIKRYVGIRQDS--.-LIhSNN.-----YMMTVRHLESLIRLSEALAKVHDNDLVTKEYVEEAHRLVKSSVV
Q8IDF0_PLAF7/423-751 DLKWLRDI.AMHP..NTIDILAECIAPKIWG..NLE.IKKGALLMMTGGVQ.K..ITSN.-CK..LRGDINMCIVGDPG..-TAKSEILKYV.E.SFAPRAIFTSGKGSTAAGL.TAAVHRDPDQGD...TVLEAGALMYADQGICCIDEFDKMDEKDRVAIHEAMEQQTISITKAG.IQAT.LNARASVLAACNPK..YGRYDTLKTFAQNVNIPAPLLSRFDLF.YTMLD.CIDIDKDTSIANHLVSMHCGEE-...------.-.--.-.-.-.-.--...........--AEKHLRANA---.-.----..--.-.--.-..........--.---.GKLDSVKLEIYLELS.K-RVKP..L....LTDEA.KYKLIQYYVSFRNIEY-.---.--SpGAQRSMRMTVRQLESLIRLSEAVAKLKFSHFVDVKHVEIACSIFKASMK
Q7YY63_CRYPV/268-626 SFRKFLEI.SQHP..NGINMLAKYVAPHVYG..YSQ.LKKGILLLLVGGVE.K..RTKD.NIK..LRGDINVCIVGDPS..-TAKSQILRFV.N.EFSTRTVYTSGKSSTAAGL.TASIHRDPDQGD...FVIEAGALMLADKGICCIDEFDKMDDKDVVAIHEAMEQQTISITKAG.VLAT.LNARASVLAACSPV..GGRYNPSKTLSQNVRISAPILSRFDLF.FVMID.DPEDVYDEVLASFIVGLHSKAT-...-----EvSgRE.-.-.-.-.--...........VTQDEASNSNT---.DnDCSFnqKKfAdNLnFsds....nnlQ-.---.--LTKDELNQYIAYA.K-TFKP..C....ITPAA.KTILVRTYKALRMGDA-.---.TSG.--AKAMRITVRQLESLIRLSEAVAKLRFSYLVTPEHVEEACQIFKSSLS
Q7QZN0_GIALA/424-793 YREAVSNM.RNDP..NIVSNLVASFAPHIYG..HET.VKLGILLQLLGGIK.K..ITRS.EHL.sIRSDINILLIGDPS..-TAKSQLLQYT.A.DFHQKAVYTSGKSSTAAGL.TAAVVTDPDTGE...YTVEAGALIRADGGLCLIDEFEKISVTDQTALHECLEQQSVSINKAG.ISIT.LKAKTPVLAAMNPI..GSRYQRNKSLKNNINISQPILSRFDLA.FVLLD.EPNKEVDNFVASRIITMQVLRNT..aYQYAKEiNpENnLsQpInIdHL...........-TQEERYAMEYCQNvGsLLNL.gGEpQ.--.-..........--.---.VPYPFKIIQLYLSLG.R-TIRP..I....LQKDA.IDEISHQWVELRRRDVG.---.---.STSRSFRITVRQLESLVRLSEAFARLCLATAITKEHVKKAAELVSTTCV
MCM3_ENTHI/167-531 DKENIKKV.MKEE..NPINLFSKSIAPSIYG..HSD.VKKAILLMLVGATP.K..IRLR.-SR..VRGDIHVMLCGDPS..-TAKSQLLRYV.M.SIAPLAVSTNGRGATGVGL.TAAVVNDPDTNQ...RTLEAGAMVLADRGICCVDEFDKMSIEDRAAMHEVMEQQTVTVQKAG.IHTG.IKCKMSILAAANPS..NGNYDFKKSPMENLYFPESLLSRFDLI.FIILD.SSTEELDRKLSQHVLKMHRHFDA..lTEQRGDdEvN-.-.VlAlVdAE...........--REKIGDAPVYQ-.DsLCMK..-EkNyLL.-..........--.---.----INSLKNMLLML.EISPTP..S....LSESA.SETIADAYVKLRENER-.-LKrIKHnFKIKTLPITARALDSLIRLAEAHARIRGSDTIDEIDAQVAVQLILMKIW
Q9SF37_ARATH/336-678 DLEFIVKF.KEEYgsDTFRRILHSVCPSIYG..HEI.VKAGITLSLFGGVR.K..HSMD.RNKvpVRGDIHVIIVGDPG..-LGKSQLLQAA.A.AISPRGIYVCGNATTRAGL.TVAVVKDSMTND...YAFEAGAMVLADGGLCCIDEFDKMTT-EHQALLEAMEQQCVSVAKAG.LVAS.LSARTSVIAAANPV..GGHYNRAKTVNENLKMSAALLSRFDLV.FILLD.KPDELLDKQVSEHIMSHHR----...------.MlGM.-.-.-.-.--...........---QTCMQK-----.-.GILY.fQDcGwTLrK..........--.---.----MTTFLRFLANC.LGNIFP..MhgilMSKDA.GEIIQKFYLKLR-----.---.-DHnTSADSTPITARQLESLVRLAQARARVDLREEITVQDAMDVVEIMKESLY
MCM8_MOUSE/44-404 DLYAIREI.QAEE..NLLKLVVNSLCPVIFG..HEL.VKAGLTLALFGGSQ.K..YADD.KNRipIRGDPHVLIVGDPG..-LGKSQMLQAA.C.NVAPRGVYVCGNTTTSSGL.TVTLSKDSSSGD...FALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAG.VVCS.LPARTSIIAAANPV..GGHYNKARTVSENLKMGSALLSRFDLV.FILLD.TPNEQHDHLLSEHVIAIRAGKQ-...------.KaVSsAtVtRvLsQDsntsvlevvseKPLSERLKVAPGEQtD.----..--.-.--.-..........--.---.-PIPHQLLRKYIGYA.RQYVHP..R....LSTDA.AQALQDFYLELRKQSQR.---.VGS.-----SPITTRQLESLIRLTEARARLELREEATREDAEDIIEIMKHSML
Q8SQX1_ENCCU/273-608 DFAEFRKI.AGAG..NTLASLVCSLYSAVYG..NEL.IKVGLVLSLFGGTK.K..SAGQ.-HS..IRSETHVLIVGDPG..-LGKSRLLLST.C.GILPKSSYVSGSFTTTAGL.TVSLTHDPVSGE...YMADAGALVVADNGICCLDEFDKIDD--HAALFEAMEDQKVSIAKGG.VICS.VPTRATVIAATNPR..HGHFDRGKTMAENIRFDPGLLSRFDLI.FLLLD.DLSEKESYMISGQILKKRRTLS-...--PGEGgFdDV.-.-.-.-.--...........---VETVRRDMFVE.-.----..--.-.DIrS..........--.--GgCVYPMDIVRKYISYA.RANVFP..V....LSKSA.SEAIKEYYVGMRSRGG-.---.---.-------VSTRDLESLVRLTEARAKVELRSIATKADAMFCIELHKRTFV
Q8SRK9_ENCCU/211-526 RLDGMGWF.ERRL..----LLVNSFAEEIQG..LEN.VKLGLLLALVSGSH.G..ADQK.SGT..-RSNSHILLVGDSG..-TGKSHLLKTC.S.RLLSPAVLTNGVGTTQAGLtTCAVR---QGRE...WVLEAGALVLADTGLCCIDEFNKLKVNEKNGLLEAMEQQTLSIAKAG.IVSS.LNTRCSVIAAINTR..H-KYSFNKSISENIMVATPLISRFDLI.FGLFD.DRDGRSDLLIVDKILGRR-----...-----P.EtGL.-.-.-.-.--...........---TDKKQGSV---.-.----..--.-.--.-..........--.---.-CWDHNILRNYIGVA.R-KRRA..V....IPDDL.NAVLLSYYHHRRKAEGAnEFN.---.--------TVRMLESLARLTEAHSKLLNSERAEEGDVYSAIILLETALG
Q8TWB5_METKA/192-488 ELEEFREL.ADK-..DPLTTFARAIAP-LPG..AEE.VGKMLALQLFSCVG.K..NSER.---..----LHVLLAGYPV..-VC-SEILHHV.LdHLAPRGVYVDLRRTELTDL.TAVLKED---RG...WALRAGAAVLADGGILAVDHLEGAPEPHRWALMEAMDKGTVTVDG--.--IA.LNARCAVLAAINPG..E-QW-PSDPPIARIDLDQDFLSHFDLIaFLGVD.PRP-----------------GEP..eEQ----.-.--.-.-.-.-.--...........---DTEVPSYT---.-.----..--.-.--.-..........--.---.------LLRRYLLYAiREHPKP..E....LTEEA.RKRLEHWYETRREEVE-.ERL.-GM.-GLPTLPVTRRQLESVERLAKAHARMRLSDDVEPEDVDIAAELVDWYLE
Q8TWR7_METKA/251-570 EVERFEEL.AEG-..DPLGEFVEAVAPHIHG..HEV.IKKAVSLQLFSCVE.-..--EG.--Q..IRERVHVLIVGDPA..-TAKSQILQHViE.HLAPRGVYVSAQHVTGAGL.TAA--AERTEDG...WTLEAGAVVMADGGVIAIDELDKASRGDLNALLEAMESGKISVAKAG.ITTT.LNARCAVLAAANPE..AGRWQGGHPI-EEINLDPALLSRFDVI.LFTRD.EPDPEQDKLVAE---RMMEAFD-...------.-.--.-.-.-.-.--...........---GEFDEIEG---.-.----..--.-.--.-..........--.---.---KYELLRRYVLYA.T-KEFPnvT....ISEDA.REELRDWFVSARQEA--.-ADrIDEgDLR-TVPVTRRQMGSVLRLARASARMRLSETVGRGDVSVALSVVEEFMK
Q9ZPT4_ARATH/300-581 KFKNFWSH.FRDTplKGRNAILRGICPQVFG..LFT.VKLAVALTLIGGVQ.H..VDAS.GTK..VRGESHLLLIGDPG..-TGKSQFLKFA.A.KLSNRAVITTGLGSTSAGL.--TVTAVKDGGE...WMLEAGALVLADGGLCCIDEFDSMREHDRATIHEAMEQQSISVAK--.IQKI.LNGMQLYLLTSLPR..YIQFVKKNFRPVLSKEAEEIISSYYRL.QRRSS.THN------AAR-----------...------.-.--.-.-.-.-.--...........--------T-----.-.----..--.-.--.-..........--.---.------TVRMLESLI.R-----..-....LAQGT.SSVIVFINQNTPKTG--.---.---.--------TKERILMVLWCHAAHARLMFRNEVTRLDAITAILCIESSMT