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PANDIT
Protein and Associated NucleotideDomains with Inferred Trees

PF00025 alignment
(19 sequences with 201 aa)


ARL2_DROME/2-176 GFLTVLKKMRQK-EREMRILLLGLDNAGKTTILKRFNGEP...IDTISPTLGFNIKTLEHNG.....YTLNMWDVGGQKSLRSYWRNYFESTDGLVWVVDSADRM..RLESCGQELQVLLQEERL...AGATLLVLCNKQDLPGALSSNEIKEILHLEDIT-T------.-.--HHWLVAGVSAVTGEKLLSSMDWLIADI
ARL2_HUMAN/2-176 GLLTILKKMKQK-ERELRLLMLGLDNAGKTTILKKFNGED...IDTISPTLGFNIKTLEHRG.....FKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQ..RMQDCQRELQSLLVEERL...AGATLLIFANKQDLPGALSSNAIREALELDSIR-S------.-.--HHWCIQGCSAVTGENLLPGIDWLLDDI
ARL3_HUMAN/2-177 GLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASED...ISHITPTQGFNIKSVQSQG.....FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRK..RFEETGQELAELLEEEKL...SCVPVLIFANKQDLLTAAPASEIAEGLNLHTIR-D------.-.--RVWQIQSCSALTGEGVQDGMNWVCKNV
ARF3_YEAST/3-177 SISKVLGKLFG--SKEMKILMLGLDKAGKTTILYKLKLNK...IKTSTPTVGFNVETVTYKN.....VKFNMWDVGGQQRLRPLWRHYFPATTALIFVIDSSARN..RMEEAKEELYSIIGEKEM...ENVVLLVWANKQDLKDAMKPQEVSDFLELEKNLKN------.-.--QPWCVIGSNALSGQGLVEGLSWISNNT
ARF3_DROME/2-171 ---KLLSKIFG--NKEMRILMLGLDAAGKTTILYKLKLGQ...SVTTIPTVGFNVETVTYKN.....VKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD..RIDEARTELHRIINDREM...RDAIILIFANKQDLPDAMKPHEIQEKLGLTRIR-D------.-.--RNWYVQPSCATSGDGLSEGLIWLTSN-
ARF_CANAL/3-176 TISKLFASLLG--RREMRILMVGLDAAGKTTILYKLKLGE...IVTTIPTIGFNVETVEYKN.....ISFTVWDVGGQDKIRPLWRYYFQNTQGIIFVVDSNDRD..RINEAREELQSMLNEDEL...KDAVLLVLANKQDLPNAMNAAEITEKMGLHSIM-N------.-.--RPWFIQATCATTGDGLYEGLEWLSNQV
ARF1_YEAST/3-176 FASKLFSNLFG--NKEMRILMVGLDGAGKTTVLYKLKLGE...VITTIPTIGFNVETVQYKN.....ISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVVDSNDRS..RIGEAREVMQRMLNEDEL...RNAAWLVFANKQDLPEAMSAAEITEKLGLHSIR-N------.-.--RPWFIQATCATSGEGLYEGLEWLSNSL
ARF3_ARATH/3-176 LFTRMFSSVFG--NKEARILVLGLDNAGKTTILYRLQMGE...VVSTIPTIGFNVETVQYNN.....IKFQVWDLGGQTSIRPYWRCYFPNTQAVIYVVDSSDTD..RIGVAKEEFHAILEEDEL...KGAVVLIFANKQDLPGALDDAAVTEALELHKIK-S------.-.--RQWAIFKTCAVKGEGLFEGLDWLSNTL
ARL1_HUMAN/4-177 FFSSIFSSLFG--TREMRILILGLDGAGKTTILYRLQVGE...VVTTIPTIGFNVETVTYKN.....LKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRD..RIGISKSELVAMLEEEEL...RKAILVVFANKQDMEQAMTSSEMANSLGLPALK-D------.-.--RKWQIFKTSATKGTGLDEAMEWLVETL
ARL1_DROME/3-176 GVLSYFRGLLG--SREMRILILGLDGAGKTTILYRLQVGE...VVTTIPTIGFNVEQVTYKN.....LKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSADRD..RIGISKDELLYMLREEEL...AGAILVVLANKQDMDGCMTVAEVHHALGLENLK-N------.-.--RTFQIFKTSATKGEGLDQAMDWLSNTL
ARL1_YEAST/3-177 IFSSMFDKLWGS-NKELRILILGLDGAGKTTILYRLQIGE...VVTTKPTIGFNVETLSYKN.....LKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDSTDKD..RMSTASKELHLMLQEEEL...QDAALLVFANKQDQPGALSASEVSKELNLVELK-D------.-.--RSWSIVASSAIKGEGITEGLDWLIDVI
ARD1_RAT/370-545 TFTKDNRVYIGP-KMEIRVVTLGLDGAGKTTILFKLKQDE...FMQPIPTIGFNVETVEYKN.....LKFTIWDVGEKHKLRPLWKHYYLNTQAVVFVVDSSHRD..RISEAHSELAKLLTEKEL...RDALLLIFANKQDVAGALSVEEITELLSLHKLCCG------.-.--RSWYIQGCDARSGMGLYEGLDWLSRQL
ARL5_CAEEL/3-177 IMAKLFQSWWI--GKKYKIIVVGLDNAGKTTILYNYVTKD...QVETKPTIGSNVEEVSYRN.....LDFVIWDIGGQESLRKSWSTYYVQTDVVIVVIDSSDTT..RIPIMKEQLHNMLQHEDL...ARAHILVLANKQDLPGAMNPAEVSTQLGLQTLRGA------.-.--RKWQINGCCAVKGEGLPEALEWIANNL
ARL4A_HUMAN/6-186 SDQTSILSNLPS-FQSFHIVILGLDCAGKTTVLYRLQFNE...FVNTVPTKGFNTEKIKVTLgnsktVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVE..RMEEAKTELHKITRISEN...QGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSS------.-.--TPWHLQPTCAIIGDGLKEGLEKLHDMI
SAR1_SCHPO/5-190 NWFYDALAMLGLVNKHAKMLFLGLDNAGKTTLLHMLKNDR...LAVMQPTLHPTSEELAIGN.....VRFTTFDLGGHQQARRLWRDYFPEVNGIVYLVDCCDFE..RLSESKAELDALLAMEEL...ARVPFLILGNKIDAPGAISEDELKAALGLYQTTGKG--VSKpVpGIRPIEVFMCSVVLRQGYGEGFKWLAQYV
SAR1_YEAST/8-190 GWFRDVLASLGLWNKHGKLLFLGLDNAGKTTLLHMLKNDR...LATLQPTWHPTSEELAIGN.....IKFTTFDLGGHIQARRLWKDYFPEVNGIVFLVDAADPE..RFDEARVELDALFNIAEL...KDVPFVILGNKIDAPNAVSEAELRSALGLLNTTGS-----QrIeGQRPVEVFMCSVVMRNGYLEAFQWLSQYI
SAR1B_ARATH/5-192 DWFYGILASLGLWQKEAKILFLGLDNAGKTTLLHMLKDER...LVQHQPTQHPTSEELSIGK.....IKFKAFDLGGHQIARRVWKDYYAKVDAVVYLVDAYDKE..RFAESKRELDALLSDEAL...ATVPFLILGNKIDIPYAASEDELRYHLGLTNFTTGKGKVTLgDsGVRPLEVFMCSIVRKMGYGEGFKWLSQYI
SAR1A_MOUSE/10-197 NGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLQMLKDDR...LGQHVPTLHPTSEELTIAG.....MTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHS..RLMESKVELNALMTDETI...SNVPILILGNKIDRTDAISEEKLREIKGLYGQTTGKGNVTLkElNARPMEVFMCSVLKRQGYGEGFRWLSQYI
CIN4_YEAST/2-187 GLLSIIRKQKLR-DKEIRCLILGLDNSGKSTIVNKLLPKDeqnNDGIMPTVGFQIHSLMIKD.....VTISLWDIGGQRTLRPFWDNYFDKTQAMIWCIDVSLSM..RFDETLQELKELINRDENrigYECAVIVVLNKIDLVEDKSELHRRCLLVESELKCLFKP---.-.-DIRIELVKCSGVTGEGIDNLRDRLVESC