Understanding the mechanisms of salamander regeneration: Building tools for therapeutic discovery
11/09/2012 - Room C209 at 14:00 - External Seminar
Salamanders are unique in that they can regenerate a vast number of clinically relevant body structures as an adult, including their limbs, heart, brain and spinal cord. Significant progress has been made in understanding the mechanisms that underscore this extensive regenerative capacity but the lack of a sequenced genome and the shortfall in advanced genetic tools present a significant impediment to rapid discovery. The current toolbox and their applications will be discussed along with the potential implications for the development of regenerative human therapies.