You'll need to have GSL (Gnu Scientific Library) installed on your system,
   version 1.11 or later.  Version 1.10 is the first GSL version that contains
   the required hypergeometric functionality. However, it has a bug that may
   cause negative probabilities to be computed (as a result of computing the
   wrong tail). This bug was fixed for 1.11 (as of writing the latest
   version).
   In the Makefile, the variable GSLPREFIX needs to be set to the proper value.
   It should be such that

   $(GSLPREFIX)/lib  contains the GSL libraries (libgsl.a libgslcblas.a and/or
      the .so variants of these).

   $(GSLPREFIX)/include contains the GSL header files -- these will be in the
      directory $(GSLPREFIX)/include/gsl

   If, for some reason, on your system the GSL library files and header files
   do not share the same prefix as described above, make the necessary
   modifications in the Makefile -- it should be straightforward.
   After you have done this, typing 'make fast' should create a functioning
   sylamer executable.

      sylamer --help or sylamer -h gives a synopsis of available options.

   The manual page is available in in the /doc directory in HTML
   (sylamer.html), PDF (sylamer.pdf), PostScript (sylamer.ps), text format
   (sylamer.txt) and as a UNIX manual page (troff format, sylamer.1).

   The R script run_sylamer_and_plot_result.R (in the directory R_scripts) can
   be used to create word significance landscape plots using Sylamer.  It
   accepts a number of parameters, which can be changed by editing the script.
   The script can be used as a starting point for further customization and
   automation. To do an example run, go to the R_scripts directory, and issue

      R --vanilla < run_sylamer_and_plot_result.R

   If you have questions or comments about this program please send a message
   to svd at sanger dot ac dot uk .