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Target Listing


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Highlighted rows in the table indicate genes with published known targets

All miRNA hits for Caenorhabditis briggsae and cbr-lin-4

183 hits found.


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Gene Name Transcript Description GO Terms Score Energy P-value Length Total Sites No. Cons Species No. miRNAs
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CBG06934 ENSCBRT00000007385 Putative serine/threonine-protein kinase ZK507.3 (EC 2.7.11.1). [Source:Uniprot/SWISSPROT;Acc:P34635]Putative serine/threonine-protein kinase ZK507.3 (EC 2.7.11.1). [Source:Uniprot/SWISSPROT;Acc:P34635] BY ORTHOLOGY TO:ZK507.3
15.2055 -21.85 6.01655e-05 1300 4 1 2 [+] picture button
CBG05116 ENSCBRT00000010296 ptr-21 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome). PTR-21 is weakly required for normal molting from L4 to adult stages. PTR-21 is also required for normal growth to full size and locomotion. [Source: WormBase]ptr-21 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome). PTR-21 is weakly required for normal molting from L4 to adult stages. PTR-21 is also required for normal growth to full size and locomotion. [Source: WormBase] BY ORTHOLOGY TO:Y65B4BR.3
15.2832 -15.94 6.69449e-05 1300 7 1 10 [+] picture button
CBG03793 ENSCBRT00000008646 B0379.1 [Source:RefSeq_peptide;Acc:NP_492659]B0379.1 [Source:RefSeq_peptide;Acc:NP_492659] BY ORTHOLOGY TO:B0379.1
15.127 -18.38 0.00043098 1300 5 1 4 [+] picture button
CBG02399 ENSCBRT00000006608 F07F6.5 [Source:RefSeq_peptide;Acc:NP_495031]F07F6.5 [Source:RefSeq_peptide;Acc:NP_495031] BY ORTHOLOGY TO:F07F6.5
15.1781 -21.91 0.000478566 1300 4 1 4 [+] picture button
CBG13344 ENSCBRT00000009488 T05H10.1 [Source:RefSeq_peptide;Acc:NP_495686]T05H10.1 [Source:RefSeq_peptide;Acc:NP_495686] BY ORTHOLOGY TO:T05H10.1
17.2878 -18.45 0.000552166 1300 2 1 3 [+] picture button
CBG13873 ENSCBRT00000013670 Y71G10AL.1b [Source:RefSeq_peptide;Acc:NP_741334]Y71G10AL.1b [Source:RefSeq_peptide;Acc:NP_741334] BY ORTHOLOGY TO:Y71G10AL.1a
14.8216 -24.15 0.000681237 1300 4 1 3 [+] picture button
CBG18375 ENSCBRT00000001576 F43D9.1 [Source:RefSeq_peptide;Acc:NP_499313]F43D9.1 [Source:RefSeq_peptide;Acc:NP_499313] BY ORTHOLOGY TO:F43D9.1
15.1321 -20.6 0.000877378 1300 4 2 6 [+] picture button
ENSCBRT00000004355 CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1). [Source:Uniprot/SWISSPROT;Acc:Q6UUV9]CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1). [Source:Uniprot/SWISSPROT;Acc:Q6UUV9] BY ORTHOLOGY TO:ENSOANT00000007238
17.7697 -26.26 0.00131786 1300 2 1 3 [+] picture button
CBG19296 ENSCBRT00000013491 C50F4.9 [Source:RefSeq_peptide;Acc:NP_505454]C50F4.9 [Source:RefSeq_peptide;Acc:NP_505454] BY ORTHOLOGY TO:C50F4.9
15.2692 -18.65 0.00147786 1300 4 1 4 [+] picture button
CBG00310 ENSCBRT00000000306 F26A3.7 [Source:RefSeq_peptide;Acc:NP_492136]F26A3.7 [Source:RefSeq_peptide;Acc:NP_492136] BY ORTHOLOGY TO:F26A3.7
14.9743 -16 0.00147786 1300 7 1 8 [+] picture button
CBG23009 ENSCBRT00000008843 CG1504-PA [Source:RefSeq_peptide;Acc:NP_608382]CG1504-PA [Source:RefSeq_peptide;Acc:NP_608382] BY ORTHOLOGY TO:CG1504-RA
15.1603 -18.71 0.00151444 1300 7 1 9 [+] picture button
CBG21904 ENSCBRT00000008217 Histidine triad nucleotide-binding protein 2 (EC 3.-.-.-) (HINT-2) (HINT-3) (HIT-17kDa) (PKCI-1-related HIT protein). [Source:Uniprot/SWISSPROT;Acc:Q9BX68]Histidine triad nucleotide-binding protein 2 (EC 3.-.-.-) (HINT-2) (HINT-3) (HIT-17kDa) (PKCI-1-related HIT protein). [Source:Uniprot/SWISSPROT;Acc:Q9BX68] BY ORTHOLOGY TO:ENSMMUT00000022943
14.5346 -19 0.00158543 1300 7 2 7 [+] picture button
CBG19768 ENSCBRT00000000366 GINS complex subunit 2 (Psf2 homolog) [Source:MarkerSymbol;Acc:MGI:1921019]GINS complex subunit 2 (Psf2 homolog) [Source:MarkerSymbol;Acc:MGI:1921019] BY ORTHOLOGY TO:ENSMUST00000034278
15.6081 -22.36 0.001801 1300 5 1 8 [+] picture button
CBG03450 ENSCBRT00000007200 DeHydrogenases, Short chain family member (dhs-12) [Source:RefSeq_peptide;Acc:NP_501850]DeHydrogenases, Short chain family member (dhs-12) [Source:RefSeq_peptide;Acc:NP_501850] BY ORTHOLOGY TO:K08F4.9
14.326 -22.07 0.00201348 1300 5 1 13 [+] picture button
CBG15880 ENSCBRT00000011069 Seven TM Receptor family member (str-183) [Source:RefSeq_peptide;Acc:NP_507108]Seven TM Receptor family member (str-183) [Source:RefSeq_peptide;Acc:NP_507108] BY ORTHOLOGY TO:T13F3.1
17.3792 -30.83 0.00205598 1300 2 1 3 [+] picture button
CBG03386 ENSCBRT00000007148 F01G10.7 [Source:RefSeq_peptide;Acc:NP_501877]F01G10.7 [Source:RefSeq_peptide;Acc:NP_501877] BY ORTHOLOGY TO:F01G10.7
14.7026 -19.71 0.00214419 1300 1 1 1 [+] picture button
ENSCBRT00000013415 COLlagen family member (col-144) [Source:RefSeq_peptide;Acc:NP_505374]COLlagen family member (col-144) [Source:RefSeq_peptide;Acc:NP_505374] BY ORTHOLOGY TO:B0222.6
14.7827 -17.9 0.00216109 1300 6 1 5 [+] picture button
CBG21231 ENSCBRT00000000924 R10E4.9 [Source:RefSeq_peptide;Acc:NP_497864]R10E4.9 [Source:RefSeq_peptide;Acc:NP_497864] BY ORTHOLOGY TO:R10E4.9
16.3302 -21.72 0.0021812 1300 9 1 17 [+] picture button
CBG05646 ENSCBRT00000005433 Y59A8B.21 [Source:RefSeq_peptide;Acc:NP_507519]Y59A8B.21 [Source:RefSeq_peptide;Acc:NP_507519] BY ORTHOLOGY TO:Y59A8B.21
14.6676 -17.66 0.00225331 1300 6 1 7 [+] picture button
CBG02828 ENSCBRT00000006246 CLASS C ACETYLCHOLINESTERASE (EC 3.1.1.7). [Source:SPTREMBL;Acc:Q9NDG9]
14.7779 -17.44 0.00227944 1300 3 2 3 [+] picture button
CBG17326 ENSCBRT00000001262 lin-14 encodes a novel protein whose activity is required for specifying the division timings of a specific group of cells during postembryonic development. lin-14 loss-of-function mutations result in the premature appearance of later larval lineages, while gain-of-function mutations result in reiteration of L1 larval stages lineages. in addition, lin-14 acts as a positive regulator of AVM, PVM, and FLP touch cell development. in regulating developmental timing, lin-14 acts, in part, by positively regulating the activity of lin-28, which encodes a cytoplasmic protein also required for proper developmental timing. at hatching, LIN-14 is detected in the nuclei of blast cells and neurons. later, from the late L1 to adult stages, LIN-14 levels are negatively regulated by translational repression mediated by lin-4, a 22-nt small temporal RNA (stRNA) that is complementary to sequences in the lin-14 3' UTR. [Source: WormBase]lin-14 encodes a novel protein whose activity is required for specifying the division timings of a specific group of cells during postembryonic development. lin-14 loss-of-function mutations result in the premature appearance of later larval lineages, while gain-of-function mutations result in reiteration of L1 larval stages lineages. in addition, lin-14 acts as a positive regulator of AVM, PVM, and FLP touch cell development. in regulating developmental timing, lin-14 acts, in part, by positively regulating the activity of lin-28, which encodes a cytoplasmic protein also required for proper developmental timing. at hatching, LIN-14 is detected in the nuclei of blast cells and neurons. later, from the late L1 to adult stages, LIN-14 levels are negatively regulated by translational repression mediated by lin-4, a 22-nt small temporal RNA (stRNA) that is complementary to sequences in the lin-14 3' UTR. [Source: WormBase] BY ORTHOLOGY TO:T25C12.1a
15.348 -18.85 0.00229229 1300 4 1 4 [+] picture button
CBG20190 ENSCBRT00000000803 unc-103 encodes an ERG-like K+ channel homolog, orthologous to human KCNH6 (OMIM:608168). UNC-103 regulates muscle activation in motility, egg-laying and male spicule protraction. UNC-103 is expressed highly in many neurons. gain-of-function alleles can be uncoordinated, while loss-of-function alleles have a more subtle defect in copulatory spicule protraction. [Source: WormBase]unc-103 encodes an ERG-like K+ channel homolog, orthologous to human KCNH6 (OMIM:608168). UNC-103 regulates muscle activation in motility, egg-laying and male spicule protraction. UNC-103 is expressed highly in many neurons. gain-of-function alleles can be uncoordinated, while loss-of-function alleles have a more subtle defect in copulatory spicule protraction. [Source: WormBase] BY ORTHOLOGY TO:C30D11.1
16.1675 -18.41 0.00254294 1300 4 2 8 [+] picture button
CBG20034 ENSCBRT00000000672 T05A1.2 [Source:RefSeq_peptide;Acc:NP_501700]T05A1.2 [Source:RefSeq_peptide;Acc:NP_501700] BY ORTHOLOGY TO:T05A1.2
14.9785 -23.75 0.00266648 1300 2 1 1 [+] picture button
CBG07207 ENSCBRT00000012256 T23F4.2 [Source:RefSeq_peptide;Acc:NP_493923]T23F4.2 [Source:RefSeq_peptide;Acc:NP_493923] BY ORTHOLOGY TO:T23F4.2
15.9684 -19.92 0.00273706 1300 4 1 9 [+] picture button
CBG05935 ENSCBRT00000009010 C08G9.1 [Source:RefSeq_peptide;Acc:NP_741444]C08G9.1 [Source:RefSeq_peptide;Acc:NP_741444] BY ORTHOLOGY TO:C08G9.1
14.4989 -23.25 0.00301193 1300 4 2 6 [+] picture button
CBG03649 ENSCBRT00000006541 nlp-10 encodes four predicted neuropeptide-like proteins. nlp-10 is part of a GGxY neuropeptide family that has members in several other nematode species. nlp-10 is expressed in a variety of neurons, including ASK, ADL, CAN, two lateral neurons, two anterior pharyngeal neurons, one tail neuron, and one male tail neuron. as loss of nlp-10 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of nlp-10-encoded peptides in development and/or behavior is not yet known. [Source: WormBase]nlp-10 encodes four predicted neuropeptide-like proteins. nlp-10 is part of a GGxY neuropeptide family that has members in several other nematode species. nlp-10 is expressed in a variety of neurons, including ASK, ADL, CAN, two lateral neurons, two anterior pharyngeal neurons, one tail neuron, and one male tail neuron. as loss of nlp-10 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of nlp-10-encoded peptides in development and/or behavior is not yet known. [Source: WormBase] BY ORTHOLOGY TO:F37A8.4
17.0319 -22.41 0.00305225 1300 1 1 3 [+] picture button
CBG04030 ENSCBRT00000009917 air-2 encodes an aurora/Ip11-related serine/threonine protein kinase that affects embryonic viability and chromosome segregation during meiosis and mitosis and is required for cytokinesis. AIR-2 has two functions during mitosis, one in chromosome segregation, and a second, independent function in cytokinesis through ZEN-4. AIR-2 and ZEN-4 may act in parallel to a second pathway that includes CYK-1. AIR-2 phosphorylates two adjacent, evolutionarily conserved C-terminal serines of the inner centromere protein ICP-1. AIR-2 forms a robust complex with CSC-1, BIR-1, and ICP-1. air-2 is expressed highly in embryos, in the mature oocytes, spermatocytes, and extruded polar bodies. [Source: WormBase]air-2 encodes an aurora/Ip11-related serine/threonine protein kinase that affects embryonic viability and chromosome segregation during meiosis and mitosis and is required for cytokinesis. AIR-2 has two functions during mitosis, one in chromosome segregation, and a second, independent function in cytokinesis through ZEN-4. AIR-2 and ZEN-4 may act in parallel to a second pathway that includes CYK-1. AIR-2 phosphorylates two adjacent, evolutionarily conserved C-terminal serines of the inner centromere protein ICP-1. AIR-2 forms a robust complex with CSC-1, BIR-1, and ICP-1. air-2 is expressed highly in embryos, in the mature oocytes, spermatocytes, and extruded polar bodies. [Source: WormBase] BY ORTHOLOGY TO:B0207.4
14.8942 -19.83 0.00346409 1300 2 1 3 [+] picture button
CBG10983 ENSCBRT00000001215 C54D1.7 [Source:RefSeq_peptide;Acc:NP_741828]C54D1.7 [Source:RefSeq_peptide;Acc:NP_741828] BY ORTHOLOGY TO:C54D1.7
16.8824 -27.16 0.00361767 1300 3 1 9 [+] picture button
CBG00458 ENSCBRT00000001931 Sucb CG10622-PB, isoform B [Source:RefSeq_peptide;Acc:NP_729076]Sucb CG10622-PB, isoform B [Source:RefSeq_peptide;Acc:NP_729076] BY ORTHOLOGY TO:CG10622-RA
14.4431 -17.82 0.00393334 1300 5 1 7 [+] picture button
CBG20682 ENSCBRT00000001459 F08G2.8 [Source:RefSeq_peptide;Acc:NP_496904]F08G2.8 [Source:RefSeq_peptide;Acc:NP_496904] BY ORTHOLOGY TO:F08G2.8
14.6959 -18.61 0.00395156 1300 4 1 3 [+] picture button
CBG20869 ENSCBRT00000000674 F59A6.4 [Source:RefSeq_peptide;Acc:NP_494922]F59A6.4 [Source:RefSeq_peptide;Acc:NP_494922] BY ORTHOLOGY TO:F59A6.4
14.0067 -12.85 0.00398035 1300 3 1 3 [+] picture button
CBG12720 ENSCBRT00000014336 lin-28 encodes a cytoplasmic protein with a cold shock domain and retroviral-type (CCHC) zinc finger motifs. LIN-28 is required for events specific to the second larval stage, which in lin-28 mutants are skipped, and is itself subject both to negative regulation (by binding of the lin-4 stRNA to an element in the lin-28 3' UTR) and to positive regulation (by LIN-14, which negatively regulates lin-4-independent inhibition also acting on the lin-28 3' UTR). [Source: WormBase]lin-28 encodes a cytoplasmic protein with a cold shock domain and retroviral-type (CCHC) zinc finger motifs. LIN-28 is required for events specific to the second larval stage, which in lin-28 mutants are skipped, and is itself subject both to negative regulation (by binding of the lin-4 stRNA to an element in the lin-28 3' UTR) and to positive regulation (by LIN-14, which negatively regulates lin-4-independent inhibition also acting on the lin-28 3' UTR). [Source: WormBase] BY ORTHOLOGY TO:F02E9.2b
16.7784 -21.01 0.0040715 1300 4 1 3 [+] picture button
CBG00115 ENSCBRT00000001548 scd-1 encodes a novel protein with several regions that are extremely glutamine (Q) rich, interspersed with other residues (usually alanine). SCD-1 affects signalling by proteins in the DAF-7/transforming growth factor (TGF)-beta pathway (DAF-1, DAF-8, and DAF-14), and the Q-rich regions of SCD-1 protein may mediate epigenetic changes of stably heritable tertiary conformation. [Source: WormBase]scd-1 encodes a novel protein with several regions that are extremely glutamine (Q) rich, interspersed with other residues (usually alanine). SCD-1 affects signalling by proteins in the DAF-7/transforming growth factor (TGF)-beta pathway (DAF-1, DAF-8, and DAF-14), and the Q-rich regions of SCD-1 protein may mediate epigenetic changes of stably heritable tertiary conformation. [Source: WormBase] BY ORTHOLOGY TO:H20J18.1a
14.3029 -17.48 0.00414074 1300 3 2 2 [+] picture button
CBG09337 ENSCBRT00000006353 Protein pellino. [Source:Uniprot/SWISSPROT;Acc:O77237]Protein pellino. [Source:Uniprot/SWISSPROT;Acc:O77237] BY ORTHOLOGY TO:CG5212-RA
16.7407 -25.21 0.00424958 1300 3 1 4 [+] picture button
CBG22936 ENSCBRT00000008770 The dpy-19 gene encodes a novel transmembrane protein whose human homolog is expressed in brain, and that is required for correct polarization and migration of the neuroblasts QL and QR. [Source: WormBase]The dpy-19 gene encodes a novel transmembrane protein whose human homolog is expressed in brain, and that is required for correct polarization and migration of the neuroblasts QL and QR. [Source: WormBase] BY ORTHOLOGY TO:F22B7.10
15.2582 -21.74 0.00429754 1300 3 1 2 [+] picture button
CBG24900 ENSCBRT00000012465 F44D12.8 [Source:RefSeq_peptide;Acc:NP_501809]F44D12.8 [Source:RefSeq_peptide;Acc:NP_501809] BY ORTHOLOGY TO:F44D12.8
15.6602 -23.17 0.00452552 1300 6 1 7 [+] picture button
CBG04784 ENSCBRT00000010598 F57A8.4 [Source:RefSeq_peptide;Acc:NP_505583]F57A8.4 [Source:RefSeq_peptide;Acc:NP_505583] BY ORTHOLOGY TO:F57A8.4
14.6609 -21.54 0.0045475 1300 5 1 11 [+] picture button
CBG16662 ENSCBRT00000014707 unc-86 encodes a transcription factor with a POU-type homeodomain that is required for correct fate determination and differentiaion in diverse neuronal lineages, including those of egg-laying neurons, mechanosensory neurons, and chemosensory interneurons. UNC-86 is orthologous to human BRN-3. UNC-86 is required for tph-1 and cat-1 expression in specific serotonergic neurons, as well as for neurite outgrowth. [Source: WormBase]unc-86 encodes a transcription factor with a POU-type homeodomain that is required for correct fate determination and differentiaion in diverse neuronal lineages, including those of egg-laying neurons, mechanosensory neurons, and chemosensory interneurons. UNC-86 is orthologous to human BRN-3. UNC-86 is required for tph-1 and cat-1 expression in specific serotonergic neurons, as well as for neurite outgrowth. [Source: WormBase] BY ORTHOLOGY TO:C30A5.7b
16.6554 -24.79 0.00468183 1300 1 1 2 [+] picture button
CBG14901 ENSCBRT00000004496 F46F11.6 [Source:RefSeq_peptide;Acc:NP_491644]F46F11.6 [Source:RefSeq_peptide;Acc:NP_491644] BY ORTHOLOGY TO:F46F11.6
16.6428 -29.67 0.00474923 1300 2 1 3 [+] picture button
CBG18077 ENSCBRT00000003173 R07E5.4 [Source:RefSeq_peptide;Acc:NP_497886]R07E5.4 [Source:RefSeq_peptide;Acc:NP_497886] BY ORTHOLOGY TO:R07E5.4
14.205 -16.44 0.00557369 1300 3 2 6 [+] picture button
CBG04636 ENSCBRT00000010530 F47B8.6 [Source:RefSeq_peptide;Acc:NP_506552]F47B8.6 [Source:RefSeq_peptide;Acc:NP_506552] BY ORTHOLOGY TO:F47B8.6
16.4704 -21.72 0.00577508 1300 7 1 9 [+] picture button
CBG15108 ENSCBRT00000010257 Y48G9A.9a [Source:RefSeq_peptide;Acc:NP_001022892]Y48G9A.9a [Source:RefSeq_peptide;Acc:NP_001022892] BY ORTHOLOGY TO:Y48G9A.9a
16.4434 -28.62 0.00595452 1300 2 1 2 [+] picture button
CBG11401 ENSCBRT00000013999 Y97E10AR.1 [Source:RefSeq_peptide;Acc:NP_505058]Y97E10AR.1 [Source:RefSeq_peptide;Acc:NP_505058] BY ORTHOLOGY TO:Y97E10AR.1
14.107 -13.12 0.00626558 1300 2 1 2 [+] picture button
CBG02783 ENSCBRT00000006142 Elongation factor G 1, mitochondrial precursor (mEF-G 1) (Elongation factor G1). [Source:Uniprot/SWISSPROT;Acc:Q96RP9]Elongation factor G 1, mitochondrial precursor (mEF-G 1) (Elongation factor G1). [Source:Uniprot/SWISSPROT;Acc:Q96RP9] BY ORTHOLOGY TO:ENSGACT00000013062
16.3489 -24.19 0.00662786 1300 4 1 4 [+] picture button
CBG22587 ENSCBRT00000009857 nhr-34 encodes a member of the nuclear receptor superfamily. phylogenetic analyses indicate that NHR-34 is a divergent nuclear receptor that likely arose from the expansion and diversification of the HNF4 (NR2A) subgroup in C. elegans. the role of NHR-34 in C. elegans development and/or behavior, and the NHR-34 expression pattern, are not yet known. [Source: WormBase]nhr-34 encodes a member of the nuclear receptor superfamily. phylogenetic analyses indicate that NHR-34 is a divergent nuclear receptor that likely arose from the expansion and diversification of the HNF4 (NR2A) subgroup in C. elegans. the role of NHR-34 in C. elegans development and/or behavior, and the NHR-34 expression pattern, are not yet known. [Source: WormBase] BY ORTHOLOGY TO:F58G6.5c
14.0838 -17.04 0.00689008 1300 5 2 7 [+] picture button
CBG15693 ENSCBRT00000011973 Y22D7AL.16 [Source:RefSeq_peptide;Acc:NP_497439]Y22D7AL.16 [Source:RefSeq_peptide;Acc:NP_497439] BY ORTHOLOGY TO:Y22D7AL.16
16.3121 -24.13 0.00691017 1300 5 1 4 [+] picture button
CBG05747 ENSCBRT00000009143 Thioredoxin reductase 3 (Thioredoxin reductase TR2) (Fragment). [Source:Uniprot/SPTREMBL;Acc:Q86VQ6]Thioredoxin reductase 3 (Thioredoxin reductase TR2) (Fragment). [Source:Uniprot/SPTREMBL;Acc:Q86VQ6] BY ORTHOLOGY TO:SINFRUT00000156741
14.1478 -21.54 0.00705449 1300 3 2 4 [+] picture button
CBG03677 ENSCBRT00000008738 B0286.1 [Source:RefSeq_peptide;Acc:NP_494776]B0286.1 [Source:RefSeq_peptide;Acc:NP_494776] BY ORTHOLOGY TO:B0286.1
14.0353 -16.28 0.007278 1300 4 1 5 [+] picture button
CBG08777 ENSCBRT00000000578 Suppressor Of Clr family member (soc-1) [Source:RefSeq_peptide;Acc:NP_504250]Suppressor Of Clr family member (soc-1) [Source:RefSeq_peptide;Acc:NP_504250] BY ORTHOLOGY TO:F41F3.2
16.1983 -20.27 0.00786053 1300 4 1 6 [+] picture button
CBG11009 ENSCBRT00000001186 unc-10 encodes a protein with zinc-finger, Q/N-rich, PDZ, and C2 domains that is homologous to vertebrate Rim1, a presynaptic protein which binds, and effects the activity of, synaptic vesicle-associated GTP-Rab3. UNC-10 is required for normal locomotion and synaptic transmission, and localizes to a subdomain of presynaptic termini, where it probably acts to regulate the priming step of presynaptic vesicle fusion by promoting conformational changes in syntaxin. [Source: WormBase]unc-10 encodes a protein with zinc-finger, Q/N-rich, PDZ, and C2 domains that is homologous to vertebrate Rim1, a presynaptic protein which binds, and effects the activity of, synaptic vesicle-associated GTP-Rab3. UNC-10 is required for normal locomotion and synaptic transmission, and localizes to a subdomain of presynaptic termini, where it probably acts to regulate the priming step of presynaptic vesicle fusion by promoting conformational changes in syntaxin. [Source: WormBase] BY ORTHOLOGY TO:T10A3.1a
14.868 -15.34 0.00801663 1300 3 2 9 [+] picture button

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