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Similarity & Homology
| Tool |
Description |
|
STRING |
Search Tool for the Retrieval of Interacting Genes/Proteins. |
|
BLAST2SRS |
Flexible retrieval of homologous protein sequences. |
| WU-BLAST2 |
Advanced WU-BLAST search with post-processing. |
Protein Function Analysis
| Tool |
Description |
|
SMART |
SMART is a "Simple Modular Architecture Research Tool" for the identification of signaling domains. |
|
gfp-cdna |
Localisation and functional characterisation of gfp-tagged novel human cDNAs. |
| AnDom |
Annotation of Domains. |
| PolyPhen |
Prediction of functional effect of human nsSNPs. |
| PROUST |
Prediction Of Unknown protein functional Sub-Types. |
Sequence Analysis
| Tool |
Description |
|
Alignment tools |
Basic tools for sequence alignment. |
| AGADIR |
An algorithm to predict the helical content of peptides. |
Structural Analysis
| Tool |
Description |
|
DisEMBL |
A computational tool for predicting disorder in proteins. DisEMBL is useful for target selection and the design of constructs as needed for many biochemical studies, particularly structural biology and structural genomics initiatives. |
|
GlobPlot |
GlobPlot is a server for exploring disorder or globularity in protein sequences. |
| The ELM Server |
The ELM Server is a resource for predicting functional sites (described by the Eukaryotic Linear Motif database) in eukaryotic proteins. |
| Coiled-coil prediction |
Structure prediction program. |
| InterPReTS |
Interaction Prediction through Tertary Structure. |
| PINTS |
Patterns In Non-homologous Tertiary Structure: Comparison/Search of structural patterns (in 3D). |
| FOLD-X |
FOLD-X is a program for calculating the folding pathways of proteins and for calculating the effect of a point mutation on the stability of a protein. The present WWW service provides an interface to both functions of the program with the option of modelling point mutations on the fly for the stability calculations. |
| Structure Prediction Guide |
A short summary of how to predict protein structure. |
| PredictProtein ** |
PredictProtein is a service for sequence analysis, and structure prediction. |
Tools Miscellaneous
| Tool |
Description |
|
SIRW |
SIRW is a web interface to SIR (Simple Indexing and Retrieval System). SIR provides the ability to simultaneously search a protein database with a sequence motif pattern and keywords, e.g. useful for restricting a pattern search to a database subset. |
|
Harvester |
Harvester collects and displays bioinformatic protein information and predictions for human proteins from various databases for realtime access. |
| Module Alerting System |
Subscribe to weekly reports on homologs of a selected domain that have been newly entered into sequence databases. |
| SHOT |
Shared Ortholog and Gene Order Tree Reconstruction Tool. |
| pI ** |
Simple isoelectric point calculation for non-modified proteins. |
| WebMol ** |
The Java PDB Viewer WebMol. |
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