nif_organism:birnlex_206 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_206 BALBc SubClass nif_organism:birnlex_597 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_597 BALBcJ SubClass obo_annot:taxonomicCommonName C rdfs:label BALB/cJ rdfs:subClassOf nif_organism:birnlex_206 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_206 class obo_annot:hasExternalSource http://ontology.neuinfo.org/NIF/Backend/BIRNLex_annotation_properties.owl#JAX-mouse-stock preferred label BALB/cJ birn_annot:hasCurationStatus http://ontology.neuinfo.org/NIF/Backend/BIRNLex_annotation_properties.owl#pending_final_vetting obo_annot:createdDate 2006-10-05 birn_annot:hasBirnlexCurator http://ontology.neuinfo.org/NIF/Backend/BIRNLex_annotation_properties.owl#Karen_Crawford http://ontology.neuinfo.org/NIF/Backend/BIRNLex_annotation_properties.owl#Bill_Bug http://ontology.neuinfo.org/NIF/Backend/BIRNLex_annotation_properties.owl#Maryann_Martone InstanceCount 0 RdfType obo_annot:synonym BALBcJ ChildCount 0 obo_annot:definingCitationURI http://www.informatics.jax.org/external/festing/mouse/docs/BALB.shtml obo_annot:modifiedDate 2007-08-04 birn_annot:birnlexDefinition A substrain of BALB/c mouse developed at Jackson Laboratory. From Jackson: nbr 150 +?.Snell to Jackson Laboratory after 1940. Males of this substrain are extremely aggressive and will fight if housed together once mature. The Lac substrain separated in 1952 is non-aggressive. Maintained by J, Ola (JLac substrain). From JAX catalog: Type: Inbred Strain TJL Mating System: Sibling x Sibling (Female x Male) Species: laboratory mouse H2 Haplotype: d Generation: F221 (14-DEC-06) Appearance: albino Related Genotype: A/A Tyrp1b/Tyrp1b Tyrc/Tyrc birn_annot:jaxMiceID 000651 class rdfs:label BALB/c rdfs:subClassOf nif_organism:birnlex_189 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_189 class obo_annot:definingCitationID PMID:10615122 PMID:17246776 owl:disjointWith nif_organism:birnlex_311 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_311 class nif_organism:birnlex_219 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_219 class nif_organism:birnlex_568 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_568 class nif_organism:birnlex_380 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_380 class nif_organism:birnlex_292 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_292 class nif_organism:birnlex_213 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_213 class nif_organism:birnlex_301 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_301 class obo_annot:hasExternalSource http://ontology.neuinfo.org/NIF/Backend/OBO_annotation_properties.owl#UMLS obo_annot:hasAbbrevSource http://ontology.neuinfo.org/NIF/Backend/BIRNLex_annotation_properties.owl#MGI preferred label BALB/c birn_annot:hasCurationStatus http://ontology.neuinfo.org/NIF/Backend/BIRNLex_annotation_properties.owl#pending_final_vetting obo_annot:createdDate 2006-10-05 birn_annot:hasBirnlexCurator http://ontology.neuinfo.org/NIF/Backend/BIRNLex_annotation_properties.owl#Bill_Bug SuperClass nif_organism:birnlex_189 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_189 SubClass rdfs:label Inbred mouse strain rdfs:subClassOf nif_organism:birnlex_224 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_224 class owl:disjointWith nif_organism:birnlex_388 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Organism.owl#birnlex_388 class editorial note Currently (2006-10-07), the children of this class have been made mutually disjoint. In reality, there may be some mixing amongst strains - e.g., some strains and substrains were derived from crosses of other inbred strains. Ultimately, the disjoint sets will need to be worked out very carefully, but this approximately is kept for now as it will likely do no harm and serve as a reminder that this issue may require more thorough review in the future. preferred label Inbred mouse strain birn_annot:hasCurationStatus http://ontology.neuinfo.org/NIF/Backend/BIRNLex_annotation_properties.owl#uncurated obo_annot:createdDate 2006-10-05 birn_annot:hasBirnlexCurator http://ontology.neuinfo.org/NIF/Backend/BIRNLex_annotation_properties.owl#Bill_Bug InstanceCount 0 RdfType ChildCount 10 obo_annot:externallySourcedDefinition Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation. obo_annot:modifiedDate 2007-08-05 obo_annot:hasDefinitionSource http://ontology.neuinfo.org/NIF/Backend/OBO_annotation_properties.owl#MeSH_defSource class InstanceCount 0 RdfType obo_annot:synonym BALBc ChildCount 1 obo_annot:definingCitationURI http://www.informatics.jax.org/external/festing/mouse/docs/BALB.shtml obo_annot:externallySourcedDefinition Jax subline (Snell, 1935) derived from Bagg stock (Memorial Hospital, NY, 1913) (Beck, J.A., et al., Geneology of mouse inbred strains (2000), Nature, Jan2000, v24, p23). One of the first inbred strains developed in the early 20th century, derived from the first inbred strain DBA. DBA was developed by Little in 1909 - D ["dilute"], B ["brown"], A["non-agouti"]. (Staats, J. The laboratory mouse. in Biology of the Laboratory Mouse (ed. Green, E.L.) 1-9 (McGraw-Hill, New York, 1966)). The sensitivity of BALB/c and C3H mice to mutagenesis by ethyl nitrosourea (ENU) has been valuable in mutagenesis programmes (Mouse mutagenesis consortium, http://www.mgu.har.mrc.ac.uk/mutabase/; German Human Genome Project, http://www.gsf.de/isg/groups/enu-mouse.html). (Beck, J.A., et al., Geneology of mouse inbred strains (2000), Nature, Jan2000, v24, p23). obo_annot:modifiedDate 2007-08-14 class