Esflurbiprofen Esflurbiprofen http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Esflurbiprofen SubClass rdfs:subClassOf Nonsteroidal Antiinflammatory Drug Nonsteroidal_Antiinflammatory_Drug http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Nonsteroidal_Antiinflammatory_Drug class rdfs:label Esflurbiprofen Concept_In_Subset FDA Established Names and Unique Ingredient Identifier Codes Terminology FDA_UNII_Code_Terminology http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#FDA_UNII_Code_Terminology class FDA_UNII_Code J5ZZK9P7MX Legacy Concept Name Esflurbiprofen code C80544 CAS_Registry 51543-39-6 CHEBI_ID CHEBI:42446 SuperClass Nonsteroidal Antiinflammatory Drug Nonsteroidal_Antiinflammatory_Drug http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Nonsteroidal_Antiinflammatory_Drug NSAIDs NSAID nonsteroidal anti-inflammatory drug Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or phospholipase C or may modulate T-cell function. (MeSH) SubClass rdfs:subClassOf Analgesic and Antipyretic Analgesic_and_Antipyretic http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Analgesic_and_Antipyretic class rdfs:label Nonsteroidal Antiinflammatory Drug Accepted_Therapeutic_Use_For Inflammation Legacy Concept Name Nonsteroidal_Antiinflammatory_Drug FULL_SYN NSAIDs NSAID nonsteroidal anti-inflammatory drug code C257 CHEBI_ID CHEBI:35475 DEFINITION Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or phospholipase C or may modulate T-cell function. (MeSH) InstanceCount 0 RdfType ChildCount 326 Semantic_Type Chemical Viewed Functionally UMLS_CUI C0003211 ALT_DEFINITION <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A group of drugs that decrease fever, swelling, pain, and redness.</ncicp:def-definition><ncicp:def-source>NCI-GLOSS</ncicp:def-source></ncicp:ComplexDefinition> Preferred_Name Nonsteroidal Antiinflammatory Drug class Chemical_Formula C15H13FO2 InstanceCount 0 RdfType ChildCount 0 Semantic_Type Pharmacologic Substance UMLS_CUI C2825249 Contributing_Source FDA Preferred_Name Esflurbiprofen class