2.24 Bioportal mappings to BRENDA tissue / enzyme source (BTO) verunknown Bioportal mappings to Cell type (CL) verunknown Bioportal mappings to Chemical entities of biological interest (CHEBI) verunknown Bioportal mappings to Drosophila gross anatomy (FBbt) ver2011-02-10 Bioportal mappings to Foundational Model of Anatomy (FMA) ver3.1 Bioportal mappings to Gene Ontology (GO) ver1.886 Bioportal mappings to Human disease (DOID) ver Bioportal mappings to International Classification of Diseases (ICD-9) ver9 Bioportal mappings to MGED Ontology (MO) ver1.3.1.1 Bioportal mappings to Malaria Ontology (IDOMAL) ver1.22 Bioportal mappings to Mammalian phenotype (MP) vernull Bioportal mappings to Medical Subject Headings (MSH) ver2011_2010_08_30 Bioportal mappings to Microarray experimental conditions (MO) ver1.3.1.1 Bioportal mappings to Minimal anatomical terminology (MAT) ver1.1 Bioportal mappings to Mosquito gross anatomy (TGMA) verunknown Bioportal mappings to NCBI organismal classification (NCBITaxon) ver1.2 Bioportal mappings to NCI Thesaurus (NCIt) ver11.01e Bioportal mappings to NIFSTD (nif) ver2.2 - December 20, 2010 Bioportal mappings to Ontology for Biomedical Investigations (OBI) ver2010-10-26 Vancouver 2010 release, RC2 Bioportal mappings to Phenotypic quality (PATO) vernull Bioportal mappings to SNOMED Clinical Terms (SNOMEDCT) ver2010_07_31 Bioportal mappings to Teleost Anatomy Ontology (TAO) vernull Bioportal mappings to Teleost anatomy and development (TAO) ver1.158 Bioportal mappings to Units of measurement (UO) vernull Bioportal mappings to Zebrafish anatomy and development (ZFA) verunknown Date: 11th May 2012 Ele Holloway Helen Parkinson James Malone Mappings to Plant structure (PO) Mappings: CRISP Thesaurus Version 2.5.2.0 Mappings: The Jackson Lab Mappings:The Arabidopsis Information Resource (TAIR) Tomasz Adamusiak Dani Welter Natalja Kurbatova lymphoid leukemia Dani Welter Leukemia associated with HYPERPLASIA of the lymphoid tissues and increased numbers of circulating malignant LYMPHOCYTES and lymphoblasts. MSH:D007945 leukemia, lymphoid lymphocytic leukemia true leukemia A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells. A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.[accessedResource: DOID:1240][accessDate: 05-04-2011] A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years. A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.[accessedResource: NCIt:C3161][accessDate: 05-04-2011] A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)[accessedResource: MSH:D007938][accessDate: 05-04-2011] Aleukaemic leukaemia [obs] Aleukaemic leukaemia [obs][accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] Aleukemic leukemia [obs] Aleukemic leukemia [obs][accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] Blood (Leukemia) Blood (Leukemia)[accessedResource: NCIt:C3161][accessDate: 05-04-2011] Chronic leukaemia [obs] Chronic leukaemia [obs][accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] Chronic leukemia [obs] Chronic leukemia [obs][accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] DOID:1240 GeneRIF:10437917 GeneRIF:11042511 GeneRIF:11489963 GeneRIF:11764099 GeneRIF:11792409 GeneRIF:11823049 GeneRIF:11830488 GeneRIF:11855785 GeneRIF:11856346 GeneRIF:11869944 GeneRIF:11893077 GeneRIF:11920534 GeneRIF:11922610 GeneRIF:11929767 GeneRIF:11937542 GeneRIF:11979742 GeneRIF:11986947 GeneRIF:11986949 GeneRIF:11996108 GeneRIF:11999550 GeneRIF:11999556 GeneRIF:12002276 GeneRIF:12002748 GeneRIF:12008082 GeneRIF:12082639 GeneRIF:12091340 GeneRIF:12096343 GeneRIF:12096925 GeneRIF:12127563 GeneRIF:12138900 GeneRIF:12139489 GeneRIF:12145702 GeneRIF:12145704 GeneRIF:12183458 GeneRIF:12186695 GeneRIF:12203795 GeneRIF:12204872 GeneRIF:12208881 GeneRIF:12217801 GeneRIF:12225794 GeneRIF:12239152 GeneRIF:12239155 GeneRIF:12384147 GeneRIF:12393620 GeneRIF:12393632 GeneRIF:12411326 GeneRIF:12414343 GeneRIF:12438221 GeneRIF:12454742 GeneRIF:12482966 GeneRIF:12496475 GeneRIF:12506112 GeneRIF:12511424 GeneRIF:12515866 GeneRIF:12533044 GeneRIF:12538698 GeneRIF:12553058 GeneRIF:12586625 GeneRIF:12592338 GeneRIF:12592353 GeneRIF:12613527 GeneRIF:12646947 GeneRIF:12648450 GeneRIF:12663445 GeneRIF:12665591 GeneRIF:12682273 GeneRIF:12682649 GeneRIF:12688322 GeneRIF:12700639 GeneRIF:12700665 GeneRIF:12705477 GeneRIF:12722639 GeneRIF:12773566 GeneRIF:12799277 GeneRIF:12816872 GeneRIF:12901974 GeneRIF:14512321 GeneRIF:14519654 GeneRIF:14521941 GeneRIF:14578205 GeneRIF:14607752 GeneRIF:14611815 GeneRIF:14615372 GeneRIF:14630792 GeneRIF:14662771 GeneRIF:14671643 GeneRIF:14689061 GeneRIF:14691303 GeneRIF:14704031 GeneRIF:14726393 GeneRIF:14737102 GeneRIF:14757439 GeneRIF:14988155 GeneRIF:14990976 GeneRIF:14996839 GeneRIF:15004329 GeneRIF:15026336 GeneRIF:15068389 GeneRIF:15070702 GeneRIF:15073036 GeneRIF:15144712 GeneRIF:15183893 GeneRIF:15187020 GeneRIF:15193261 GeneRIF:15199122 GeneRIF:15223639 GeneRIF:15298716 GeneRIF:15298960 GeneRIF:15304397 GeneRIF:15325703 GeneRIF:15351976 GeneRIF:15388576 GeneRIF:15454492 GeneRIF:15475071 GeneRIF:15475073 GeneRIF:15512811 GeneRIF:15515013 GeneRIF:15516987 GeneRIF:15541480 GeneRIF:15545599 GeneRIF:15567461 GeneRIF:15583855 GeneRIF:15585652 GeneRIF:15604256 GeneRIF:15611294 GeneRIF:15645140 GeneRIF:15674415 GeneRIF:15676214 GeneRIF:15687235 GeneRIF:15704129 GeneRIF:15705792 GeneRIF:15723065 GeneRIF:15723338 GeneRIF:15723339 GeneRIF:15725473 GeneRIF:15735695 GeneRIF:15744340 GeneRIF:15756419 GeneRIF:15815718 GeneRIF:15833859 GeneRIF:15834506 GeneRIF:15845894 GeneRIF:15856008 GeneRIF:15856017 GeneRIF:15860672 GeneRIF:15895983 GeneRIF:15959530 GeneRIF:15964800 GeneRIF:16002684 GeneRIF:16005964 GeneRIF:16081688 GeneRIF:16088313 GeneRIF:16103065 GeneRIF:16109713 GeneRIF:16130282 GeneRIF:16139274 GeneRIF:16179912 GeneRIF:16210627 GeneRIF:16271957 ICD9:207 ICD9:207.8 ICD9:207.80 ICD9:207.81 ICD9:208 ICD9:208.8 ICD9:208.80 ICD9:208.81 ICD9:208.9 ICD9:208.90 James Malone LEUK NOS W/O ACHV RMSN LEUK NOS W/O ACHV RMSN[accessedResource: ICD9:208.90][accessDate: 05-04-2011] LEUKEMIA NOS W/O REMSION Leukaemia Leukaemia NOS Leukaemia NOS[accessedResource: SNOMEDCT:188767008][accessDate: 05-04-2011] Leukaemia morphology Leukaemia morphology[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] Leukaemia of unspecified cell type Leukaemia of unspecified cell type[accessedResource: SNOMEDCT:188762002][accessDate: 05-04-2011] Leukaemia, NOS Leukaemia, NOS, without mention of remission Leukaemia, NOS, without mention of remission[accessedResource: SNOMEDCT:93143009][accessDate: 05-04-2011] Leukaemia, NOS[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] Leukaemia, disease Leukaemia, disease[accessedResource: SNOMEDCT:93143009][accessDate: 05-04-2011] Leukaemia, no ICD-O subtype Leukaemia, no ICD-O subtype[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] Leukaemia[accessedResource: SNOMEDCT:93143009][accessDate: 05-04-2011] Leukemia NOS Leukemia NOS (disorder) Leukemia NOS (disorder)[accessedResource: SNOMEDCT:188767008][accessDate: 05-04-2011] Leukemia NOS[accessedResource: SNOMEDCT:188767008][accessDate: 05-04-2011] Leukemia morphology Leukemia morphology[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] Leukemia of unspecified cell type Leukemia of unspecified cell type (disorder) Leukemia of unspecified cell type (disorder)[accessedResource: SNOMEDCT:188762002][accessDate: 05-04-2011] Leukemia of unspecified cell type[accessedResource: SNOMEDCT:188762002][accessDate: 05-04-2011] Leukemia, NOS Leukemia, NOS, without mention of remission Leukemia, NOS, without mention of remission[accessedResource: SNOMEDCT:93143009][accessDate: 05-04-2011] Leukemia, NOS[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] Leukemia, disease Leukemia, disease (disorder) Leukemia, disease (disorder)[accessedResource: SNOMEDCT:93143009][accessDate: 05-04-2011] Leukemia, disease[accessedResource: SNOMEDCT:93143009][accessDate: 05-04-2011] Leukemia, morphology (morphologic abnormality) Leukemia, morphology (morphologic abnormality)[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] Leukemia, no ICD-O subtype Leukemia, no ICD-O subtype (morphologic abnormality) Leukemia, no ICD-O subtype (morphologic abnormality)[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] Leukemia, no ICD-O subtype[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] Leukemias Leukemias, General Leukemias, General[accessedResource: NCIt:C3161][accessDate: 05-04-2011] Leukemias[accessedResource: MSH:D007938][accessDate: 05-04-2011] MSH:D007938 NCIt:C3161 OT LEU UN CL WO ACH RMSN OT LEU UN CL WO ACH RMSN[accessedResource: ICD9:208.80][accessDate: 05-04-2011] OTH LEUK UNS CL W RMSON OTH LEUK UNS CL W RMSON[accessedResource: ICD9:208.81][accessDate: 05-04-2011] OTH LEUK UNS CL W/O RMSN OTH LEUK W/O ACHV RMSN OTH LEUK W/O ACHV RMSN[accessedResource: ICD9:207.80][accessDate: 05-04-2011] OTH SPF LEUK W REMSION OTH SPF LEUK W REMSION[accessedResource: ICD9:207.81][accessDate: 05-04-2011] OTH SPF LEUK W/O REMSION Other leukaemia of unspecified cell type Other leukaemia of unspecified cell type[accessedResource: SNOMEDCT:188766004][accessDate: 05-04-2011] Other leukemia of unspecified cell type Other leukemia of unspecified cell type (disorder) Other leukemia of unspecified cell type (disorder)[accessedResource: SNOMEDCT:188766004][accessDate: 05-04-2011] Other leukemia of unspecified cell type in remission Other leukemia of unspecified cell type in remission[accessedResource: ICD9:208.81][accessDate: 05-04-2011] Other leukemia of unspecified cell type without mention of having achieved remission Other leukemia of unspecified cell type without mention of having achieved remission[accessedResource: ICD9:208.80][accessDate: 05-04-2011] Other leukemia of unspecified cell type without mention of remission Other leukemia of unspecified cell type[accessedResource: ICD9:208.8][accessDate: 05-04-2011] Other specified leukaemia Other specified leukaemia NOS Other specified leukaemia NOS[accessedResource: SNOMEDCT:188761009][accessDate: 05-04-2011] Other specified leukaemia[accessedResource: SNOMEDCT:188751002][accessDate: 05-04-2011] Other specified leukemia Other specified leukemia (disorder) Other specified leukemia (disorder)[accessedResource: SNOMEDCT:188751002][accessDate: 05-04-2011] Other specified leukemia NOS Other specified leukemia NOS (disorder) Other specified leukemia NOS (disorder)[accessedResource: SNOMEDCT:188761009][accessDate: 05-04-2011] Other specified leukemia NOS[accessedResource: SNOMEDCT:188761009][accessDate: 05-04-2011] Other specified leukemia in remission Other specified leukemia in remission[accessedResource: ICD9:207.81][accessDate: 05-04-2011] Other specified leukemia without mention of having achieved remission Other specified leukemia without mention of having achieved remission[accessedResource: ICD9:207.80][accessDate: 05-04-2011] Other specified leukemia without mention of remission Other specified leukemia[accessedResource: ICD9:207][accessDate: 05-04-2011] SNOMEDCT:188751002 SNOMEDCT:188761009 SNOMEDCT:188762002 SNOMEDCT:188766004 SNOMEDCT:188767008 SNOMEDCT:190024009 SNOMEDCT:190025005 SNOMEDCT:190029004 SNOMEDCT:190161003 SNOMEDCT:190162005 SNOMEDCT:87163000 SNOMEDCT:93143009 Subacute leukaemia [obs] Subacute leukaemia [obs][accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] Subacute leukemia [obs] Subacute leukemia [obs][accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011] This is potentially too broad as well as overlaps with lymphoma and should be obsoleted. Tomasz Adamusiak Unspecified leukemia Unspecified leukemia without mention of having achieved remission Unspecified leukemia without mention of having achieved remission[accessedResource: ICD9:208.90][accessDate: 05-04-2011] Unspecified leukemia without mention of remission Unspecified leukemia[accessedResource: ICD9:208.9][accessDate: 05-04-2011] [M]Leukaemia NOS [M]Leukaemia NOS[accessedResource: SNOMEDCT:190025005][accessDate: 05-04-2011] [M]Leukaemia unspecified, NOS [M]Leukaemia unspecified, NOS[accessedResource: SNOMEDCT:190029004][accessDate: 05-04-2011] [M]Leukaemias unspecified [M]Leukaemias unspecified[accessedResource: SNOMEDCT:190024009][accessDate: 05-04-2011] [M]Leukemia NOS [M]Leukemia NOS[accessedResource: SNOMEDCT:190025005][accessDate: 05-04-2011] [M]Leukemia unspecified, NOS [M]Leukemia unspecified, NOS[accessedResource: SNOMEDCT:190029004][accessDate: 05-04-2011] [M]Leukemias unspecified [M]Leukemias unspecified[accessedResource: SNOMEDCT:190024009][accessDate: 05-04-2011] [M]leukemia NOS (morphologic abnormality) [M]leukemia NOS (morphologic abnormality)[accessedResource: SNOMEDCT:190025005][accessDate: 05-04-2011] [M]leukemia unspecified, NOS (morphologic abnormality) [M]leukemia unspecified, NOS (morphologic abnormality)[accessedResource: SNOMEDCT:190029004][accessDate: 05-04-2011] [M]leukemias unspecified (morphologic abnormality) [M]leukemias unspecified (morphologic abnormality)[accessedResource: SNOMEDCT:190024009][accessDate: 05-04-2011] [X]Other leukaemia of unspecified cell type [X]Other leukaemia of unspecified cell type[accessedResource: SNOMEDCT:190162005][accessDate: 05-04-2011] [X]Other leukemia of unspecified cell type [X]Other leukemia of unspecified cell type (disorder) [X]Other leukemia of unspecified cell type (disorder)[accessedResource: SNOMEDCT:190162005][accessDate: 05-04-2011] [X]Other leukemia of unspecified cell type[accessedResource: SNOMEDCT:190162005][accessDate: 05-04-2011] [X]Other specified leukaemias [X]Other specified leukaemias[accessedResource: SNOMEDCT:190161003][accessDate: 05-04-2011] [X]Other specified leukemias [X]Other specified leukemias (disorder) [X]Other specified leukemias (disorder)[accessedResource: SNOMEDCT:190161003][accessDate: 05-04-2011] [X]Other specified leukemias[accessedResource: SNOMEDCT:190161003][accessDate: 05-04-2011] chronic leukaemia NOS chronic leukemia chronic leukemia - category (morphologic abnormality) chronic leukemia NOS chronic leukemia NOS (disorder) chronic leukemia of unspecified cell type chronic leukemia, disease (disorder) START EFO_0004289 http://www.ebi.ac.uk/efo/ -1507697833 lymphoid leukemia ISA EFO_0000565 http://www.ebi.ac.uk/efo/ -1507814180 leukemia ISA EFO_0001642 http://www.ebi.ac.uk/efo/ -1507783493 lymphoid neoplasm ISA EFO_0000311 http://www.ebi.ac.uk/efo/ -1507816261 cancer ISA EFO_0000616 http://www.ebi.ac.uk/efo/ -1507813373 neoplasm ISA EFO_0000408 http://www.ebi.ac.uk/efo/ -1507815324 disease ISA Disposition http://www.ifomis.org/bfo/1.1/snap# -363181882 disposition ISA SpecificallyDependentContinuant http://www.ifomis.org/bfo/1.1/snap# 884003725 material property ISA EFO_0000001 http://www.ebi.ac.uk/efo/ -1507819175 experimental factor