Search results for Q61091

Showing 19 results out of 60 in All results

Protein sequences (6 results found)

Q61091

(FZD8_MOUSE)

Frizzled-8 Fz-8 mFz8
Mus musculus (Reviewed)
Secondary accession number(s): A2RTK9

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Source: UniProtKB  ID: FZD8_MOUSE

View all 6 results for Protein sequences

Genomes (1 results found)

ENSMUSG00000036904

frizzled homolog 8 (Drosophila) [Source:MGI Symbol;Acc:MGI:108460]
Species: Mus musculus

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Source: Ensembl Gene  ID: ENSMUSG00000036904

Nucleotide sequences (12 results found)

U43321

Mus musculus putative transmembrane receptor (frizzled 8) gene, complete cds.

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Source: Sequence (Release)  ID: U43321

BC132543

Mus musculus frizzled homolog 8 (Drosophila), mRNA (cDNA clone MGC:164174 IMAGE:40130820), complete cds.

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Source: Sequence (Release)  ID: BC132543

BC138062

Mus musculus frizzled homolog 8 (Drosophila), mRNA (cDNA clone MGC:169686 IMAGE:8861081), complete cds.

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Source: Sequence (Release)  ID: BC138062

View all 12 results for Nucleotide sequences

Macromolecular structures (2 results found)

Crystal structure of XWnt8 in complex with the cysteine-rich domain of Frizzled 8

Accession: 4f0a
SIGNALING PROTEIN x-ray diffraction entry at resolution 3.25

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Source: PDBe  ID: 4F0A

CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF MOUSE FRIZZLED 8 (MFZ8)

Accession: 1ijy
SIGNALING PROTEIN x-ray diffraction entry at resolution 1.35

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Source: PDBe  ID: 1IJY

Small molecules (24 results found)

lysine

A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6.

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Source: ChEBI  ID: 25094

hexadehydroastechrome

An iron(III) hydroxamate that is astechrome in which the 3-methylbut-2-en-1-yl groups have been oxidised to 3-methylbuta-1,3-dien-1-yl groups. First isolated from Aspergillus fumigatus.

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Source: ChEBI  ID: 73878

glycine

The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain.

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Source: ChEBI  ID: 15428

View all 24 results for Small molecules

Gene expression (2 results found)

Fzd8

Fzd8, frizzled homolog 8 (Drosophila) [Source:MGI Symbol;Acc:MGI:108460], is expressed in 3 baseline experiment(s); developmental stage: DN1; organism: Mus musculus; organism part: cerebellum, heart, brain, lung, kidney, liver, testis, thymus, hippocampus, spleen

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Source: Baseline Expression Atlas Genes  ID: ENSMUSG00000036904

Fzd8

Fzd8, frizzled homolog 8 (Drosophila) [Source:MGI Symbol;Acc:MGI:108460], is differentially expressed in 3 experiment(s); infect: Trypanosoma brucei TREU927; genotype: Taf10-/-, L-Pex5 knock-out

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Source: Differential Expression Atlas Genes  ID: ENSMUSG00000036904

Molecular interactions (1 results found)

fzd8_mouse

Frizzled-8

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Source: IntAct Interactors  ID: EBI-6171689

Reactions, pathways & diseases (8 results found)

Frizzled receptors bind Wnts

The highly conserved Wnt signaling proteins play critical roles in guiding pattern formation, cell fate decision, and morphogenetic movement during animal development. They bind to the Frizzled (FZD) family of seven-pass transmembrane proteins and initiate at least three different intracellular signaling pathways. Historically they were considered t...

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Source: Reactome  ID: REACT_21306

Frizzled receptors bind Wnts

This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a...

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Source: Reactome  ID: REACT_239159

GPCR ligand binding

This event has been computationally inferred from an event that has been demonstrated in another species.The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a...

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Source: Reactome  ID: REACT_231468

View all 8 results for Reactions, pathways & diseases

Protein families (4 results found)

FRIZZLED DOMAIN

The frizzled (fz) domain is an extracellular domain of about 120 amino acids.It was first identified in the alpha-1 chain of type XVIII collagen and in members of the Frizzled family of seven transmembrane (7TM) proteins which act as receptors for secreted Wingless (Wg)/Wnt glycoproteins. In addition to these proteins, one or two copies of the fz do...

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Source: InterPro  ID: IPR020067

GPCR, FAMILY 2-LIKE

G protein-coupled receptors (GPCRs) constitute a vast protein family that encompasses a wide range of functions, including various autocrine, paracrine and endocrine processes. They show considerable diversity at the sequence level, on the basis of which they can be separated into distinct groups. The term clan can be used to describe the GPCRs, as ...

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Source: InterPro  ID: IPR017981

FRIZZLED PROTEIN

Frizzleds are seven transmembrane-spanning proteins that constitute an unconventional class of G protein-coupled receptors. They have important regulatory roles during embryonic development. Frizzleds expose their large N terminus on the extracellular side. The N-terminal, extracellular cysteine-rich domain (CRD) has been implicated as the Wnt bindi...

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Source: InterPro  ID: IPR000539

View all 4 results for Protein families