Search results for UCHL1

Showing 19 results out of 1,337 in All results

Gene expression (23 results found)

UCHL1

Macaca mulatta UCHL1, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) [Source:HGNC Symbol;Acc:HGNC:12513], is expressed in 1 baseline experiment(s); organism: Macaca mulatta; organism part: heart, testis, cerebellum, brain, kidney

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Source: Baseline Expression Atlas Genes  ID: ENSMMUG00000013071

UCHL1

Papio anubis UCHL1, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) [Source:HGNC Symbol;Acc:HGNC:12513], is expressed in 1 baseline experiment(s); organism part: skeletal muscle, brain temporal lobe, lymph node, brain frontal cortex, bone marrow, lung, kidney, colon, brain ...

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Source: Baseline Expression Atlas Genes  ID: ENSPANG00000016830

UCHL1

Homo sapiens UCHL1, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) [Source:HGNC Symbol;Acc:HGNC:12513], is expressed in 4 baseline experiment(s); cell line: H1-hESC, SK-N-SH, HUVEC cell line, HSMM cell line, HMEC cell line, hMSC-AT cell line, IMR-90, NHEK cell line, MCF-7, BJ ...

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Source: Baseline Expression Atlas Genes  ID: ENSG00000154277

View all 23 results for Gene expression

Literature (535 results found)

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Source: MEDLINE  ID: 25605410

Association between ubiquitin carboxy-terminal hydrolase-L1 S18Y variant and risk of Parkinson's disease: the impact of ethnicity and onset age.

Liu YChen YYLiu HYao CJZhu XXChen DJYang JLu YJCao JY
(2015 Feb) Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 36(2):179-88

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Source: MEDLINE  ID: 25370916

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Nucleotide sequences (210 results found)

AIC49936

synthetic construct partial UCHL1

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Source: Coding (Release)  ID: AIC49936

View all 210 results for Nucleotide sequences

Genomes (161 results found)

ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

Approved Symbol: UCHL1
Approved Name: ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Status: (Approved)
Aliases: PGP9.5 Uch-L1
Locus Type: gene with protein product
Chromosome: 4p13

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Source: HGNC  ID: HGNC:12513

View all 161 results for Genomes

Protein sequences (288 results found)

P09936

(UCHL1_HUMAN)

Ubiquitin carboxyl-terminal hydrolase isozyme L1 UCH-L1
Homo sapiens (Reviewed)
Secondary accession number(s): Q4W5K6, Q71UM0

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Source: UniProtKB  ID: UCHL1_HUMAN

View all 288 results for Protein sequences

Macromolecular structures (8 results found)

Solution structure of UCHL1 S18Y variant

Accession: 2len
Hydrolase solution nmr entry at resolution unknown

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Source: PDBe  ID: 2len

View all 8 results for Macromolecular structures

Small molecules (4 results found)

CHEMBL1243701

Assay Type: Binding

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Source: ChEMBL Assay  ID: CHEMBL1243701

CHEMBL903551

Assay Type: Binding

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Source: ChEMBL Assay  ID: CHEMBL903551

View all 4 results for Small molecules

Molecular interactions (31 results found)

uchl1_mouse

Ubiquitin carboxyl-terminal hydrolase isozyme L1

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Source: IntAct Interactors  ID: EBI-1635245

uchl1_rat

Ubiquitin carboxyl-terminal hydrolase isozyme L1

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Source: IntAct Interactors  ID: EBI-8848346

uchl1_human

Ubiquitin carboxyl-terminal hydrolase isozyme L1

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Source: IntAct Interactors  ID: EBI-714860

View all 31 results for Molecular interactions

Reactions, pathways & diseases (46 results found)

Uchl5 deubiquitinates TGFBR1

Recombinant mouse Uchl5 (Uch37) exogenously expressed in HEK293 cells deubiquitinates recombinant human TGFBR1. This stabilizes TGFBR1 and prolongs signaling by TGF-beta receptor complex. Deubiqutination of Smad7 has not been examined in this context (Wicks et al. 2005).
Stable Id: REACT_120821
Type: Reaction
Species: Homo sapiens

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Source: Reactome  ID: 2179313

UBIQUITIN CARBOXYL-TERMINAL ESTERASE L1

DESCRIPTION UCHL1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and ... et al., 1983). CLONING Day and Thompson (1987) cloned UCHL1 cDNA. The deduced protein, which they ...

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Source: OMIM  ID: 191342

View all 46 results for Reactions, pathways & diseases

Protein families (4 results found)

UBIQUITIN CARBOXYL-TERMINAL HYDROLASE L1

Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is a deubiquitinase that has dual hydrolase and ... the pattern of ubiquitination. Mutations in the UCHL1 gene has been linked to neurodegenerative diseases. UCHL1 also pays a major role in oncogenesis.

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Source: InterPro  ID: IPR030297

View all 4 results for Protein families

Samples & ontologies (27 results found)

SAME550232

Sample Name: B6;129P2-Uchl1/Mmnc synonym: B6;129-Uchl1, B6;129P2-Uchl1/Mmnc, B6.129P2-Uchl1/Mmnc ... Allele Symbol: Uchl1 Allele Name: targeted mutation 1, Deltagen Gene ID: MGI:103149 Gene Symbol: Uchl1 Gene Name: ubiquitin carboxy-terminal hydrolase L1 synonym: B6;129P2-Uchl1/Mmnc, B6;129-Uchl1 ...

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Source: BioSamples  ID: SAME550232

View all 27 results for Samples & ontologies