Search results for TPM1
Showing 20 results out of 1,496 in All results
Genomes (73 results found)
Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently [Source:SGD;Acc:S000005023]
Species: Saccharomyces cerevisiae
Approved Symbol: TPM1
Approved Name: tropomyosin 1 (alpha)
Locus Type: gene with protein product
Nucleotide sequences (822 results found)
Sus scrofa (pig) TPM1
Protein sequences (199 results found)
Tropomyosin alpha-1 chain
Homo sapiens (Reviewed)
Secondary accession number(s): B7Z5T7, D9YZV2, D9YZV3, D9YZV8, P09494, P10469, Q6DV89, Q6DV90, Q7Z6L8, Q86W64, Q96IK2, Q9UCI1, Q9UCI2, Q9UCY9, Q9Y427
Small molecules (1 results found)
A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine.
Gene expression (36 results found)
Molecular interactions (35 results found)
Part of the CCSB-H11 dataset.
Reactions, pathways & diseases (26 results found)
... tropomyosin genes, TPM1 is the most versatile and encodes at least 10 tissue-specific variants via alternative splicing and/or the use of 2 promoters. The TPM1 variants encode proteins of either 248 or 284 ... heart RNA, Denz et al. (2004) cloned a TPM1 splice variant that they called TPM1-kappa. The TPM1-kappa ...
Protein families (3 results found)
awaiting family name
Literature (171 results found)
Significance of sarcomere gene mutations analysis in the end-stage phase of hypertrophic cardiomyopathy.
(2014 Sep 01) The American journal of cardiology, 114(5):769-76
Samples & ontologies (128 results found)
Sample Name: STOCK Tpm1/WtsiH synonym: 129S/SvEvBrd-Tpm1/WtsiH, STOCK Tpm1/WtsiH, 129-Tpm1/WtsiH ... :4842867 Allele Symbol: Tpm1 Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute Gene ID: MGI:98809 Gene Symbol: Tpm1 Gene Name: tropomyosin 1, alpha
Sample Name: 129-Tpm1/WtsiH synonym: 129S/SvEvBrd-Tpm1/WtsiH, STOCK Tpm1/WtsiH, 129-Tpm1/WtsiH ... :4842867 Allele Symbol: Tpm1 Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute Gene ID: MGI:98809 Gene Symbol: Tpm1 Gene Name: tropomyosin 1, alpha
EBI web (2 results found)
... organization, including BNI1 and TPM1, which presumably act to polarize the ...
Analysis of alignment error and sitewise constraint in mammalian comparative genomics Gregory Jordan European Bioinformatics Institute University of Cambridge A dissertation submitted for the degree of Doctor of Philosophy November 30, 2011 To my parents, who kept us thinking and playing This dissert...