Search results for TARDBP
Showing 21 results out of 1,737 in All results
Molecular interactions (42 results found)
Nucleotide sequences (657 results found)
Homo sapiens (human) TARDBP protein
Protein sequences (504 results found)
TAR DNA-binding protein 43 TDP-43
Homo sapiens (Reviewed)
Secondary accession number(s): A4GUK4, A4GUK5, A4GUK6, B2R629, B4DJ45, E2PU12, Q53H27, Q6FI92, Q96DJ0
Gene expression (57 results found)
Homo sapiens TARDBP, TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571], is differentially expressed in 71 experiment(s); sampling time point: time point 3, time point 2, time point 1, time point 4, time point 5; fraction: hepatocyte-like cell foci, all cells; developmental stage ...
Bos taurus TARDBP, TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571], is expressed in 2 baseline experiment(s); organism part: duodenum, liver, kidney, adipose, lung, hypothalamus, spleen, muscle
Macaca mulatta TARDBP, TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571], is expressed in 2 baseline experiment(s); organism part: colon, brain, spleen, cerebellum, liver, testis, kidney, heart
Genomes & metagenomes (78 results found)
Approved Symbol: TARDBP
Approved Name: TAR DNA binding protein
Aliases: TDP-43 ALS10
Locus Type: gene with protein product
Small molecules (1 results found)
Component Synonym: TDP43, TARDBP, TAR DNA-binding protein 43, TDP-43
Reactions, pathways & diseases (23 results found)
... frontotemporal dementia (ALS10) is caused by heterozygous mutation in the TARDBP gene (605078 ... with mutations in the TARDBP gene develop frontotemporal dementia with TDP43-positive inclusions ... . Patients with TARDBP mutations and frontotemporal dementia may or may not have associated signs of ...
DESCRIPTION The TARDBP gene encodes the 43-kD TAR DNA-binding protein, which was originally ... encoding a 43-kD TAR DNA-binding protein, TARDBP, which they called TDP43. The deduced 414-amino acid TARDBP contains a ribonucleoprotein (RNP)-binding domain and a glycine-rich region. Northern blot ...
Protein expression data (2 results found)
Heat-shock is an acute insult to the mammalian proteome. The sudden elevation in temperature has far-reaching effects on protein metabolism, leads to a rapid inhibition of most protein synthesis, and the induction of protein chaperones. Using heat-shock in cells of neuronal (SH-SY5Y) and glial (CCF-STTG1) lineage, in conjunction with detergent extra...
Human Ataxin-2 (ATXN2) gene locus variants have been associated with obesity, diabetes mellitus type 1 and hypertension in genome-wide association studies, while mouse studies showed the knock-out of Atxn2 to lead to obesity, insulin resistance and dyslipidemia. Intriguingly, the deficiency of ATXN2 protein orthologues in yeast and flies rescues the...
Literature (310 results found)
(2016 Oct) Acta neuropathologica, 132(4):545-61
Familial ALS-linked Mutations in Profilin 1 Exacerbate TDP-43-induced Degeneration in the Retina of Drosophila Melanogaster through an Increase in the Cytoplasmic Localization of TDP-43.
(2016 Sep 15) The Journal of biological chemistry
Samples & ontologies (60 results found)
Sample Name: Tardbp (C03) tm1b embryo Material: embryo Derived From: SAME1836628
Sample Name: Tardbp (C03) tm1b sperm Material: sperm Derived From: SAME1836628
Sample Name: C57BL/6N-Tardbp/H sperm Material: sperm Derived From: SAME1835586
EBI web (2 results found)
... Q4LE52 SF3B4 CUGBP1 Q8N499 RBM39 TARDBP ELAVL1:2 2 RANBP6 IPO5 ELAVL1:3 3 QKI ... C11orf41 RAD54L2 ELAVL2:1 1 Q4LE52 SF3B4 CUGBP1 Q8N499 RBM39 TARDBP ELAVL2 ... CUGBP1 Q8N499 RBM39 TARDBP ELAVL3:2 2 RANBP6 IPO5 ELAVL3:3 3 QKI RBPMS ELAVL3:4 ...
SC_Gent_Treated Table: Gene sets enriched in phenotype 1 (Gentamicin treated) (4 samples) GS GS DETAILS SIZE ES NES NOM p-val FDR q-val FWER p-val RANK AT MAX LEADING EDGE follow link to MSigDB 1 VPS35:2 8 -0.69 -1.68 0.033 0.492 0.42 334 tags=25%, list=4%, signal=26% 2 UBP3:1 9 -0.63 -1.58 0 0.542 0...