Search results for TARDBP
Showing 16 results out of 1,552 in All results
Literature (275 results found)
Genomes (83 results found)
Approved Symbol: TARDBP
Approved Name: TAR DNA binding protein
Aliases: TDP-43 ALS10
Locus Type: gene with protein product
Nucleotide sequences (573 results found)
Homo sapiens (human) TARDBP protein
Protein sequences (463 results found)
TAR DNA-binding protein 43 TDP-43
Homo sapiens (Reviewed)
Secondary accession number(s): A4GUK4, A4GUK5, A4GUK6, B2R629, B4DJ45, E2PU12, Q53H27, Q6FI92, Q96DJ0
Small molecules (1 results found)
Component Synonym: TDP43, TARDBP, TAR DNA-binding protein 43, TDP-43
Gene expression (22 results found)
Homo sapiens TARDBP, TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571], is differentially expressed in 68 experiment(s); organism part: pancreas; treatment: blood alcohol content 0.02%declining, treated with TNF alpha, blood alcohol content 0.08%, stimulated, blood alcohol content 0 ...
Monodelphis domestica TARDBP, TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571], is expressed in 1 baseline experiment(s); organism part: heart, cerebellum, brain, testis
Ovis aries TARDBP, TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571], is expressed in 1 baseline experiment(s); organism part: ovarian follicles, corpus luteum, mammary gland; developmental stage: juvenile, adult; sex: female
Molecular interactions (42 results found)
Reactions, pathways & diseases (23 results found)
... frontotemporal dementia (ALS10) is caused by heterozygous mutation in the TARDBP gene (605078 ... with mutations in the TARDBP gene develop frontotemporal dementia with TDP43-positive inclusions ... . Patients with TARDBP mutations and frontotemporal dementia may or may not have associated signs of ...
DESCRIPTION The TARDBP gene encodes the 43-kD TAR DNA-binding protein, which was originally ... encoding a 43-kD TAR DNA-binding protein, TARDBP, which they called TDP43. The deduced 414-amino acid TARDBP contains a ribonucleoprotein (RNP)-binding domain and a glycine-rich region. Northern blot ...
Protein expression data (1 results found)
Transactive response DNA-binding protein 43 (TDP-43) is a predominantly nuclear, ubiquitously expressed RNA and DNA-binding protein. It recognises and binds to UG repeats and is involved in pre-mRNA splicing, mRNA stability and microRNA metabolism. TDP-43 is essential in early embryonic development but accumulates in cytoplasmic aggregates in amyotr...
Samples & ontologies (68 results found)
Sample Name: C57BL/6N-Tardbp/H sperm Material: sperm Derived From: SAME1835586
Sample Name: Tardbp (C03) tm1b embryo Material: embryo Derived From: SAME1836628
Sample Name: Tardbp (C03) tm1b sperm Material: sperm Derived From: SAME1836628