Search results for TARDBP
Showing 17 results out of 1,606 in All results
Molecular interactions (42 results found)
Nucleotide sequences (570 results found)
Homo sapiens (human) TARDBP protein
Protein sequences (496 results found)
TAR DNA-binding protein 43 TDP-43
Homo sapiens (Reviewed)
Secondary accession number(s): A4GUK4, A4GUK5, A4GUK6, B2R629, B4DJ45, E2PU12, Q53H27, Q6FI92, Q96DJ0
Genomes & metagenomes (75 results found)
Approved Symbol: TARDBP
Approved Name: TAR DNA binding protein
Aliases: TDP-43 ALS10
Locus Type: gene with protein product
Small molecules (1 results found)
Component Synonym: TDP43, TARDBP, TAR DNA-binding protein 43, TDP-43
Gene expression (23 results found)
Homo sapiens TARDBP, TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571], is differentially expressed in 72 experiment(s); clinical history: Lot II; infect: herpes simplex virus G207, influenza A virus, low-pathogenic seasonal influenza A (H1N1) virus, lentivirus expressing SETDB1, GLV ...
Monodelphis domestica TARDBP, TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571], is expressed in 1 baseline experiment(s); organism part: liver, heart, kidney, brain, cerebellum, testis
Macaca mulatta TARDBP, Uncharacterized protein [Source:UniProtKB/TrEMBL;Acc:F7GJ34], is expressed in 2 baseline experiment(s); organism part: liver, colon, spleen, cerebellum, heart, kidney, brain, testis
Reactions, pathways & diseases (23 results found)
... frontotemporal dementia (ALS10) is caused by heterozygous mutation in the TARDBP gene (605078 ... with mutations in the TARDBP gene develop frontotemporal dementia with TDP43-positive inclusions ... . Patients with TARDBP mutations and frontotemporal dementia may or may not have associated signs of ...
DESCRIPTION The TARDBP gene encodes the 43-kD TAR DNA-binding protein, which was originally ... encoding a 43-kD TAR DNA-binding protein, TARDBP, which they called TDP43. The deduced 414-amino acid TARDBP contains a ribonucleoprotein (RNP)-binding domain and a glycine-rich region. Northern blot ...
Protein expression data (2 results found)
Heat-shock is an acute insult to the mammalian proteome. The sudden elevation in temperature has far-reaching effects on protein metabolism, leads to a rapid inhibition of most protein synthesis, and the induction of protein chaperones. Using heat-shock in cells of neuronal (SH-SY5Y) and glial (CCF-STTG1) lineage, in conjunction with detergent extra...
Human Ataxin-2 (ATXN2) gene locus variants have been associated with obesity, diabetes mellitus type 1 and hypertension in genome-wide association studies, while mouse studies showed the knock-out of Atxn2 to lead to obesity, insulin resistance and dyslipidemia. Intriguingly, the deficiency of ATXN2 protein orthologues in yeast and flies rescues the...
Literature (299 results found)
Samples & ontologies (74 results found)
Sample Name: C57BL/6N-Tardbp/H sperm Material: sperm Derived From: SAME1835586
Sample Name: Tardbp (C03) tm1b sperm Material: sperm Derived From: SAME1836628
Sample Name: Tardbp (C03) tm1b embryo Material: embryo Derived From: SAME1836628