Search results for SKI

Showing 15 results out of 16,538 in All results

Reactions, pathways & diseases (110 results found)


Stable Id: REACT_7460
Type: Protein
Species: Homo sapiens

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Source: Reactome  ID: 173473

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Genomes (440 results found)

SKI proto-oncogene

Approved Symbol: SKI
Approved Name: SKI proto-oncogene
Status: (Approved)
Locus Type: gene with protein product
Chromosome: 1p36.33

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Source: HGNC  ID: HGNC:10896

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Nucleotide sequences (10,192 results found)


Trachemys scripta subsp. elegans partial mRNA for putative Ski oncogene (ski gene)

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Source: Sequence (Release)  ID: AJ243135

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Protein sequences (2,168 results found)



Ski oncogene
Homo sapiens (Reviewed)
Secondary accession number(s): Q5SYT7

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Source: UniProtKB  ID: SKI_HUMAN

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Macromolecular structures (59 results found)

Crystal Structure of a Smad4-Ski Complex

Accession: 1mr1
SIGNALING PROTEIN x-ray diffraction entry at resolution 2.85

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Source: PDBe  ID: 1MR1

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Small molecules (23 results found)


MW: 552.45
AlogP: 5.47
Canonical Smiles: COc1cc(Nc2c(cnc3cc(c(OC)cc23)c4coc(CN5CCN(C)CC5)c4)C#N)c(Cl)cc1Cl
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 1
Polar Surface Area: 86.79

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Source: ChEMBL Molecule  ID: CHEMBL219557


MW: 490
AlogP: 4.38
Canonical Smiles: Cc1nc(Nc2ncc(s2)C(=O)Nc3c(C)cccc3Cl)cc(n1)N4CCN(CCF)CC4
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 2
Polar Surface Area: 114.52

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Source: ChEMBL Molecule  ID: CHEMBL240158

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Gene expression (519 results found)


Macaca mulatta SKI, v-ski avian sarcoma viral oncogene homolog [Source:HGNC Symbol;Acc:HGNC:10896], is not differentially expressed in any experiments

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Source: Differential Expression Atlas Genes  ID: ENSMMUG00000010280

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Molecular interactions (93 results found)


Ski oncogene

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Source: IntAct Interactors  ID: EBI-6392357


Ski oncogene

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Source: IntAct Interactors  ID: EBI-347281

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Protein families (17 results found)


Ski is involved in oncogenic transformation and enhancement of muscle differentiation by blocking TGF-beta signaling. Ski binds directly to the Smad3/4 complex and negatively regulates TGF-beta ... determination of cells to the myogenic lineage. Ski is a component of the histone deacetylase complex (HDAC ...

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Source: InterPro  ID: IPR028760

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Enzymes (1 results found)

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Source: IntEnz  ID:

Literature (2,689 results found)

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Source: MEDLINE  ID: 24854291

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EBI web (5 results found)

Search: All SMART signatures < InterPro < EMBL-EBI

Filter your results Member database CATH-Gene3D HAMAP PANTHER PIRSF PRINTS PROSITE patterns PROSITE profiles Pfam PfamB ProDom SMART SUPERFAMILY TIGRFAMs InterPro results for all SMART signatures Myelin proteolipid protein PLP (IPR001614) SMART signature: SM00002 Neurohypophysial hormone (IPR000981) ...

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Source: Site 

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