Search results for PARK2

Showing 24 results out of 1,827 in All results

Reactions, pathways & diseases (48 results found)

PARK2

Stable Id: R-HSA-201579
Type: Protein
Species: Homo sapiens

Related data | Views

Source: Reactome  ID: 201579

View all 48 results for Reactions, pathways & diseases

Genomes (251 results found)

parkin RBR E3 ubiquitin protein ligase

Approved Symbol: PARK2
Approved Name: parkin RBR E3 ubiquitin protein ligase
Status: (Approved)
Aliases: PDJ AR-JP parkin
Locus Type: gene with protein product
Chromosome: 6q25.2-q27

Related data | Views

Source: HGNC  ID: HGNC:8607

View all 251 results for Genomes

Nucleotide sequences (232 results found)

AKI69871

synthetic construct partial PARK2

Related data | Views

Source: Coding (Update)  ID: AKI69871

AKI69870

synthetic construct partial PARK2

Related data | Views

Source: Coding (Update)  ID: AKI69870

View all 232 results for Nucleotide sequences

Protein sequences (577 results found)

O60260

(PRKN2_HUMAN)

E3 ubiquitin-protein ligase parkin Parkin
Homo sapiens (Reviewed)
Secondary accession number(s): A3FG77, A8K975, D3JZW7, D3K2X0, Q5TFV8, Q5VVX4, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07

Related data | Views

Source: UniProtKB  ID: PRKN2_HUMAN

View all 577 results for Protein sequences

Macromolecular structures (2 results found)

Solution Structure of RING2 Domain from Parkin

Accession: 2lwr
LIGASE solution nmr entry at resolution unknown

Related data | Views

Source: PDBe  ID: 2lwr

Solution Structure of IBR-RING2 Tandem Domain from Parkin

Accession: 2m48
LIGASE solution nmr entry at resolution unknown

Related data | Views

Source: PDBe  ID: 2m48

Small molecules (2 results found)

CHEMBL1827163

Assay Type: Functional

Related data | Views

Source: ChEMBL Assay  ID: CHEMBL1827163

CHEMBL1827624

Assay Type: Functional

Related data | Views

Source: ChEMBL Assay  ID: CHEMBL1827624

Gene expression (37 results found)

PARK2

Gallus gallus PARK2, parkin RBR E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:8607], is expressed in 2 baseline experiment(s); organism: Gallus gallus; organism part: kidney, heart, brain, skeletal muscle, testis, liver

Related data | Views

Source: Baseline Expression Atlas Genes  ID: ENSGALG00000011562

PARK2

Monodelphis domestica PARK2, parkin RBR E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:8607], is expressed in 1 baseline experiment(s); organism part: kidney, heart, brain, cerebellum, testis, liver; organism: Monodelphis domestica

Related data | Views

Source: Baseline Expression Atlas Genes  ID: ENSMODG00000023274

PARK2

Papio anubis PARK2, parkin RBR E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:8607], is expressed in 1 baseline experiment(s); organism part: brain cerebellum, brain frontal cortex, brain temporal lobe, heart, liver, lymph node, spleen, thymus, lung, kidney, skeletal muscle, brain ...

Related data | Views

Source: Baseline Expression Atlas Genes  ID: ENSPANG00000022007

View all 37 results for Gene expression

Molecular interactions (117 results found)

park2-ranbp2-8

Interaction between PARK2 and RANBP2 by coimmunoprecipitation

Related data | Views

Source: IntAct Interactions  ID: EBI-973674

park2-ranbp2-9

Interaction between PARK2 and RANBP2 by coimmunoprecipitation

Related data | Views

Source: IntAct Interactions  ID: EBI-973698

park2-ranbp2-10

Interaction between PARK2 and RANBP2 by coimmunoprecipitation

Related data | Views

Source: IntAct Interactions  ID: EBI-973897

View all 117 results for Molecular interactions

Protein families (2 results found)

TF314529

awaiting family name
awaiting annotation

Related data | Views

Source: TreeFam  ID: TF314529

TF321123

awaiting family name
awaiting annotation

Related data | Views

Source: TreeFam  ID: TF321123

Enzymes (22 results found)

PRKN2_MOUSE

E3 ubiquitin-protein ligase parkin
... blocks its E2-binding site. Activation of PARK2 requires 2 steps: (1) phosphorylation at Ser-65 by ... by the RING-0 region via an allosteric mechanism and converting PARK2 to its fully-active form ...

Related data | Views

Source: Enzyme Portal  ID: PRKN2_MOUSE

PRKN2_RAT

E3 ubiquitin-protein ligase parkin
... blocks its E2-binding site. Activation of PARK2 requires 2 steps: (1) phosphorylation at Ser-65 by ... by the RING-0 region via an allosteric mechanism and converting PARK2 to its fully-active form ...

Related data | Views

Source: Enzyme Portal  ID: PRKN2_RAT

PINK1_MOUSE

Serine/threonine-protein kinase PINK1, mitochondrial
PTEN-induced putative kinase protein 1

Related data | Views

Source: Enzyme Portal  ID: PINK1_MOUSE

View all 22 results for Enzymes

Samples & ontologies (128 results found)

PARKIN-FBXW7-CUL1 UBIQUITIN LIGASE COMPLEX

Ontology: cellular component
A ubiquitin ligase complex containing Parkin (PARK2), the F-box protein FBXW7 (also called SEL-10) and a cullin from the Cul1 subfamily; substrate specificity is conferred by the F-box protein.

Related data | Views

Source: GO  ID: GO:1990452

View all 128 results for Samples & ontologies