Search results for DNMT1

Showing 20 results out of 4,561 in All results

Enzymes (30 results found)

DNMT1_MOUSE

DNA (cytosine-5)-methyltransferase 1
Allosterically regulated. The binding of 5-methylcytosine-containing DNA to the N-terminal parts of DNMT1 causes an allosteric activation of the catalytic domain by a direct interaction of its Zn-binding domain with the catalytic domain

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Source: Enzyme Portal  ID: DNMT1_MOUSE

View all 30 results for Enzymes

Genomes (232 results found)

DNA (cytosine-5-)-methyltransferase 1

Approved Symbol: DNMT1
Approved Name: DNA (cytosine-5-)-methyltransferase 1
Status: (Approved)
Aliases: MCMT CXXC9
Locus Type: gene with protein product
Chromosome: 19p13.2

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Source: HGNC  ID: HGNC:2976

View all 232 results for Genomes

Nucleotide sequences (524 results found)

AAH57461

Danio rerio (zebrafish) dnmt1 protein

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Source: Coding (Release)  ID: AAH57461

AAH92517

Homo sapiens (human) DNMT1 protein

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Source: Coding (Release)  ID: AAH92517

AAI63893

Danio rerio (zebrafish) dnmt1 protein

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Source: Coding (Release)  ID: AAI63893

View all 524 results for Nucleotide sequences

Protein sequences (555 results found)

P26358

(DNMT1_HUMAN)

DNA (cytosine-5)-methyltransferase 1 Dnmt1
Homo sapiens (Reviewed)
Secondary accession number(s): A0AV63, B7ZLW6, Q9UHG5, Q9ULA2, Q9UMZ6

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Source: UniProtKB  ID: DNMT1_HUMAN

View all 555 results for Protein sequences

Macromolecular structures (23 results found)

SET7/9-Dnmt1 K142me1 complex

Accession: 3os5
TRANSFERASE x-ray diffraction entry at resolution 1.69

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Source: PDBe  ID: 3os5

View all 23 results for Macromolecular structures

Small molecules (42 results found)

CHEMBL1036444

Assay Type: Binding

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Source: ChEMBL Assay  ID: CHEMBL1036444

CHEMBL2050446

Assay Type: Binding

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Source: ChEMBL Assay  ID: CHEMBL2050446

View all 42 results for Small molecules

Gene expression (310 results found)

DNMT1

Macaca mulatta DNMT1, DNA (cytosine-5-)-methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976], is expressed in 2 baseline experiment(s); organism part: brain, heart, kidney, liver, cerebellum, testis; organism: Macaca mulatta

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Source: Baseline Expression Atlas Genes  ID: ENSMMUG00000014604

DNMT1

Monodelphis domestica DNMT1, DNA (cytosine-5-)-methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976], is expressed in 1 baseline experiment(s); organism part: heart, brain, kidney, testis, cerebellum, liver; organism: Monodelphis domestica

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Source: Baseline Expression Atlas Genes  ID: ENSMODG00000005463

DNMT1

Papio anubis DNMT1, DNA (cytosine-5-)-methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976], is expressed in 1 baseline experiment(s); organism part: thymus, liver, spleen, lymph node, heart, brain frontal cortex, brain cerebellum, brain temporal lobe, colon, brain pituitary, bone marrow, lung ...

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Source: Baseline Expression Atlas Genes  ID: ENSPANG00000001264

View all 310 results for Gene expression

Molecular interactions (108 results found)

uhfr1-dnmt1

ICBP90 coimmunoprecipitates DNMT1 and HDAC1 in Jurkat lysates

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Source: IntAct Interactions  ID: EBI-1549007

hdac1-dnmt1

ICBP90 and DNMT1 coimmunoprecipitate with HDAC1 in Jurkat lysates

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Source: IntAct Interactions  ID: EBI-1549015

dnmt1-hdac1

ICBP90 and HDAC1 coimmunoprecipitate with DNMT1 in Jurkat lysates

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Source: IntAct Interactions  ID: EBI-1549022

View all 108 results for Molecular interactions

Reactions, pathways & diseases (186 results found)

DNMT1

Stable Id: R-HSA-212181
Type: Protein
Species: Homo sapiens

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Source: Reactome  ID: 212181

Dnmt1

Stable Id: R-MMU-573310
Type: Protein
Species: Mus musculus

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Source: Reactome  ID: 573310

View all 186 results for Reactions, pathways & diseases

Protein families (6 results found)

DNA (CYTOSINE-5)-METHYLTRANSFERASE 1, METAZOA

This entry represents DNA (cytosine-5)-methyltransferase 1 (Dnmt1;), which methylates CpG residues ... established in development. DNA methylation is coordinated with methylation of histones. Dnmt1 ... the N terminus of Dnmt1 binds to HDAC2 (histone deacetylase-2) as well as to DMAP1 (Dnmt1-associated ...

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Source: InterPro  ID: IPR017198

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Samples & ontologies (583 results found)

RGS6-DNMT1-DMAP1 COMPLEX

Ontology: cellular component
A protein complex formed by the association of RGS6, a negative regulator of heterotrimeric G protein signaling, with the DMAP1-Dnmt1 transcriptional repressor complex; in the complex, RGS6 inhibits the transcriptional repressor activity of DMAP1.

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Source: GO  ID: GO:0070313

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