Search results for BRCA1

Showing 19 results out of 32,512 in All results

Reactions, pathways & diseases (324 results found)

Brca1

Stable Id: REACT_27430
Type: Protein
Species: Mus musculus

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Source: Reactome  ID: 912454

BRCA1

Stable Id: REACT_117716
Type: Protein
Species: Gallus gallus

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Source: Reactome  ID: 265944

p-S1189,S1524,S1542-BRCA1

Stable Id: REACT_2590
Type: Protein
Species: Homo sapiens

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Source: Reactome  ID: 75234

View all 324 results for Reactions, pathways & diseases

Genomes (719 results found)

breast cancer 1, early onset

Approved Symbol: BRCA1
Approved Name: breast cancer 1, early onset
Status: (Approved)
Aliases: RNF53 BRCC1 PPP1R53
Locus Type: gene with protein product
Chromosome: 17q21.31

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Source: HGNC  ID: HGNC:1100

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Nucleotide sequences (9,831 results found)

AJ403962

Cercopithecus aethiops partial BRCA1 gene for BRCA1 homologue

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Source: Sequence (Release)  ID: AJ403962

AJ403964

Macaca fascicularis partial BRCA1 gene for BRCA1 homologue

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Source: Sequence (Release)  ID: AJ403964

AJ403965

Aotus trivirgatus partial BRCA1 gene for BRCA1 homologue

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Source: Sequence (Release)  ID: AJ403965

View all 9831 results for Nucleotide sequences

Protein sequences (7,117 results found)

P38398

(BRCA1_HUMAN)

Breast cancer type 1 susceptibility protein
Homo sapiens (Reviewed)
Secondary accession number(s): O15129, Q1RMC1, Q3LRJ0, Q3LRJ6, Q6IN79, Q7KYU9

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Source: UniProtKB  ID: BRCA1_HUMAN

View all 7117 results for Protein sequences

Macromolecular structures (76 results found)

Solution structure of the BRCA1/BARD1 RING-domain heterodimer

Accession: 1jm7
ANTITUMOR solution nmr entry at resolution unknown

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Source: PDBe  ID: 1JM7

View all 76 results for Macromolecular structures

Small molecules (45 results found)

CHEMBL1785941

Assay Type: Binding

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Source: ChEMBL Assay  ID: CHEMBL1785941

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Gene expression (842 results found)

BRCA1

Pongo abelii BRCA1, breast cancer 1, early onset [Source:HGNC Symbol;Acc:HGNC:1100], is not expressed in any baseline experiments

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Source: Baseline Expression Atlas Genes  ID: ENSPPYG00000008363

BRCA1

Pongo abelii BRCA1, breast cancer 1, early onset [Source:HGNC Symbol;Acc:HGNC:1100], is not differentially expressed in any experiments

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Source: Differential Expression Atlas Genes  ID: ENSPPYG00000008363

BRCA1

Homo sapiens BRCA1, breast cancer 1, early onset [Source:HGNC Symbol;Acc:HGNC:1100], is expressed in 4 baseline experiment(s); cell line: H1-hESC, SK-N-SH, HUVEC cell line, HSMM cell line, HMEC cell line, hMSC-AT cell line, GM12878, IMR-90, K562, NHEK cell line, MCF-7, BJ, HepG2, HeLa-S3, CD20 ...

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Source: Baseline Expression Atlas Genes  ID: ENSG00000012048

View all 842 results for Gene expression

Molecular interactions (378 results found)

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Source: IntAct Interactors  ID: EBI-1165296

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Protein families (32 results found)

BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN (BRCA1)

... breast cancer. Mutations in the DNA-damage repair protein BRCA1 are believed to be responsible for 45% of inherited breast cancer and more than 80% of inherited breast and ovarian cancer. The BRCA1 ...

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Source: InterPro  ID: IPR011364

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Enzymes (1 results found)

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Source: IntEnz  ID: 3.6.4.12

Literature (9,410 results found)

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Source: MEDLINE  ID: 24125081

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EBI web (21 results found)

TmWorkshop_Part6_Computational_AJY.pdf

... • INTRODUCTION: BRCA1 or BRCA2 germline mutations increase the risk of developing ... tumours. BRCA1 methylation has been shown to occur in sporadic breast ... frequency of BRCA1 methylation in 143 primary sporadic breast tumours along ...
http://www.ebi.ac.uk/Rebholz-srv/TmWorkshop_Part6_Computational_AJY.pdf

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Source: Site 

View all 21 results for EBI web