Search results for BRCA1
Showing 19 results out of 30,684 in All results
Nucleotide sequences (8,671 results found)
Pan paniscus partial BRCA1 gene for BRCA1 homologue
Cercopithecus aethiops partial BRCA1 gene for BRCA1 homologue
Cercopithecus hamlyni partial BRCA1 gene for BRCA1 homologue
Genomes (674 results found)
Approved Symbol: BRCA1
Approved Name: breast cancer 1, early onset
Aliases: RNF53 BRCC1 PPP1R53
Locus Type: gene with protein product
Protein sequences (6,922 results found)
Breast cancer type 1 susceptibility protein
Homo sapiens (Reviewed)
Secondary accession number(s): O15129, Q3LRJ0, Q3LRJ6, Q6IN79, Q7KYU9
Macromolecular structures (75 results found)
Small molecules (45 results found)
Assay Type: Binding
Gene expression (653 results found)
BRCA1, breast cancer 1, early onset [Source:HGNC Symbol;Acc:1100], is not expressed in any baseline experiments
BRCA1, breast cancer 1, early onset [Source:HGNC Symbol;Acc:1100], is not differentially expressed in any experiments
BRCA1, breast cancer 1, early onset [Source:HGNC Symbol;Acc:1100], is expressed in 4 baseline experiment(s); cell line: HPC-PL cell line, H1-hESC, SK-N-SH, CD34-positive mobilized cell cell line, HUVEC cell line, HSMM cell line, HMEC cell line, hMSC-AT cell line, GM12878, IMR-90, K562, NHEK cell ...
Molecular interactions (377 results found)
Reactions, pathways & diseases (211 results found)
DESCRIPTION BRCA1 plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. BRCA1 forms several distinct complexes through association with different ... Miki et al. (1994) identified cDNA sequences corresponding to the BRCA1 gene by positional cloning of ...
Protein families (32 results found)
... breast cancer. Mutations in the DNA-damage repair protein BRCA1 are believed to be responsible for 45% of inherited breast cancer and more than 80% of inherited breast and ovarian cancer. The BRCA1 ...
Literature (9,300 results found)
(2014 Sep) British journal of health psychology, 19(3):465-85
Samples & ontologies (3,699 results found)
EBI web (24 results found)
... • INTRODUCTION: BRCA1 or BRCA2 germline mutations increase the risk of developing ... tumours. BRCA1 methylation has been shown to occur in sporadic breast ... frequency of BRCA1 methylation in 143 primary sporadic breast tumours along ...