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2009

From purified GPCRs to drug discovery: the promise of protein-based methodologies.

Alkhalfioui F, Magnin T, Wagner R
Curr Opin Pharmacol July 2009  

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2008

Catalysis within the lipid bilayer-structure and mechanism of the MAPEG family of integral membrane proteins.

Molina DM, Eshaghi S, Nordlund P
Curr Opin Struct Biol Aug 2008  

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2007

The CorA family: structure and function revisited.

Niegowski D, Eshaghi S
Cell Mol Life Sci (64) Dec 2007 2564-74
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A genomic strategy for cloning, expressing and purifying efflux proteins of the major facilitator superfamily.

Szakonyi G, Leng D, Ma P, Bettaney KE, Saidijam M, Ward A, Zibaei S, Gardiner AT, Cogdell RJ, Butaye P, Kolsto AB, O'reilly J, Hope RJ, Rutherford NG, Hoyle CJ, Henderson PJ
J Antimicrob Chemother (59) Aug 2007 1265-70
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Biochemistry. A missing link in membrane protein evolution.

Poolman B, Geertsma ER, Slotboom DJ
Science (315) May 2007 1229-31
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2006

Aquaporin gating.

Hedfalk K, Tornroth-Horsefield S, Nyblom M, Johanson U, Kjellbom P, Neutze R
Curr Opin Struct Biol (16) Oct 2006 447-56
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Microbial drug efflux proteins of the major facilitator superfamily.

Saidijam M, Benedetti G, Ren Q, Xu Z, Hoyle CJ, Palmer SL, Ward A, Bettaney KE, Szakonyi G, Meuller J, Morrison S, Pos MK, Butaye P, Walravens K, Langton K, Herbert RB, Skurray RA, Paulsen IT, O'reilly J, Rutherford NG, Brown MH, Bill RM, Henderson PJ
Curr Drug Targets (7) Sept 2006 793-811
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2005

Eukaryotic membrane protein overproduction in Lactococcus lactis.

Kunji ER, Chan KW, Slotboom DJ, Floyd S, O'Connor R, Monne M
Curr Opin Biotechnol (16) Dec 2005 546-51
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Structural biology of G protein-coupled receptors.

Bioorg Med Chem Lett (15) Oct 2005 3654-7
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Active membrane transport and receptor proteins from bacteria.

Saidijam M, Bettaney KE, Szakonyi G, Psakis G, Shibayama K, Suzuki S, Clough JL, Blessie V, Abu-Bakr A, Baumberg S, Meuller J, Hoyle CK, Palmer SL, Butaye P, Walravens K, Patching SG, O'reilly J, Rutherford NG, Bill RM, Roper DI, Phillips-Jones MK, Henderson PJ
Biochem Soc Trans (33) Oct 2005 867-72
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Structural genomics of GPCRs.

Trends Biotechnol (23) April 2005 103-8
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Functional analysis of detergent-solubilized and membrane-reconstituted ATP-binding cassette transporters.

Poolman B, Doeven MK, Geertsma ER, Biemans-Oldehinkel E, Konings WN, Rees DC
Methods Enzymol (400) Feb 2005 429-59
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