BioModels Database logo

BioModels Database

spacer

BIOMD0000000036 - Tyson1999_CircClock

 

 |   |   |  Send feedback
Reference Publication
Publication ID: 20540926
Tyson JJ, Hong CI, Thron CD, Novak B.
A simple model of circadian rhythms based on dimerization and proteolysis of PER and TIM.
Biophys. J. 1999 Nov; 77(5): 2411-2417
Department of Biology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA. tyson@vt.edu  [more]
Model
Original Model: BIOMD0000000036.origin
Submitter: Nicolas Le Novère
Submission ID: MODEL6619720081
Submission Date: 13 Sep 2005 13:55:42 UTC
Last Modification Date: 25 Feb 2015 13:24:41 UTC
Creation Date: 07 Jul 2005 15:19:53 UTC
Encoders:  Nicolas Le Novère
set #1
bqbiol:hasTaxon Taxonomy Drosophila melanogaster
bqbiol:is KEGG Pathway dme04710
bqbiol:isVersionOf Gene Ontology regulation of circadian rhythm
Notes

To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.

In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.


To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.

Model
Publication ID: 20540926 Submission Date: 13 Sep 2005 13:55:42 UTC Last Modification Date: 25 Feb 2015 13:24:41 UTC Creation Date: 07 Jul 2005 15:19:53 UTC
Mathematical expressions
Reactions
transcription translation mRNA degradation protein degradation
Per phosphorylation and degradation      
Physical entities
Compartments Species
default EmptySet    
CYTOPLASM M Pt  
Global parameters
N_A      
Reactions (5)
 
 transcription [EmptySet] → [M];   {Pt}
 
 translation [EmptySet] → [Pt];   {M}
 
 mRNA degradation [M] → [EmptySet];  
 
 protein degradation [Pt] → [EmptySet];  
 
 Per phosphorylation and degradation [Pt] → [EmptySet];  
 
   Spatial dimensions: 3.0  Compartment size: 1.0
 
   EmptySet
Compartment: default
Initial amount: 0.0
Constant
 
  Spatial dimensions: 3.0  Compartment size: 1.0
 
   M
Compartment: CYTOPLASM
Initial amount: 1.0
 
 Pt
Compartment: CYTOPLASM
Initial amount: 1.0
 
Global Parameters (1)
 
   N_A
Value: 6.0221367E23
Constant
 
transcription (3)
 
   Vm
Value: 1.0
Constant
 
   Pcrit
Value: 0.1
Constant
 
   Keq
Value: 200.0
Constant
 
translation (1)
 
   Vp
Value: 0.5
Constant
 
mRNA degradation (1)
 
   km
Value: 0.1
Constant
 
protein degradation (1)
 
   kp3
Value: 0.1
Constant
 
Per phosphorylation and degradation (4)
 
   kp1
Value: 10.0
Constant
 
   kp2
Value: 0.03
Constant
 
   Jp
Value: 0.05
Constant
 
   Keq
Value: 200.0
Constant
 
Representative curation result(s)
Representative curation result(s) of BIOMD0000000036

Curator's comment: (updated: 13 Dec 2006 17:12:43 GMT)

Figures 2 and 3A reproduced in COPASI 4.0 build 19

spacer
spacer