CHEBI:9753 - troglitazone

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ChEBI Name troglitazone
ChEBI ID CHEBI:9753
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C24H27NO5S
Net Charge 0
Average Mass 441.54000
Monoisotopic Mass 441.161
InChI InChI=1S/C24H27NO5S/c1-13-14(2)21-18(15(3)20(13)26)9-10-24(4,30-21)12-29-17-7-5-16(6-8-17)11-19-22(27)25-23(28)31-19/h5-8,19,26H,9-12H2,1-4H3,(H,25,27,28)
InChIKey GXPHKUHSUJUWKP-UHFFFAOYSA-N
SMILES Cc1c(C)c2OC(C)(CCc2c(C)c1O)COc1ccc(CC2SC(=O)NC2=O)cc1
Roles Classification
Chemical Role(s): antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
Application(s): platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
anticoagulant
An agent that prevents blood clotting.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
hypoglycemic agent
A drug which lowers the blood glucose level.
vasodilator agent
A drug used to cause dilation of the blood vessels.
anticonvulsant
A drug used to prevent seizures or reduce their severity.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing troglitazone (CHEBI:9753) has role anticoagulant (CHEBI:50249)
troglitazone (CHEBI:9753) has role anticonvulsant (CHEBI:35623)
troglitazone (CHEBI:9753) has role antineoplastic agent (CHEBI:35610)
troglitazone (CHEBI:9753) has role antioxidant (CHEBI:22586)
troglitazone (CHEBI:9753) has role hypoglycemic agent (CHEBI:35526)
troglitazone (CHEBI:9753) has role platelet aggregation inhibitor (CHEBI:50427)
troglitazone (CHEBI:9753) has role vasodilator agent (CHEBI:35620)
troglitazone (CHEBI:9753) is a chromanes (CHEBI:23230)
troglitazone (CHEBI:9753) is a thiazolidinone (CHEBI:48891)
IUPAC Name
5-{4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione
INNs Sources
troglitazona ChEBI
troglitazone ChEBI
troglitazonum ChEBI
Synonyms Sources
(+-)-all-rac-5-(p-((6-Hydroxy-2,5,7,8-tetramethyl-2-chromanyl)methoxy)benzyl)-2,4-thiazolidinedione ChemIDplus
5-(4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2,4-dione ChemIDplus
Rezulin (TN) KEGG DRUG
Romglizone ChemIDplus
Troglitazone KEGG DRUG
Database Links Databases
2767 DrugCentral
D00395 KEGG DRUG
DB00197 DrugBank
LSM-4890 LINCS
Troglitazone Wikipedia
US4572912 Patent
View more database links
Registry Numbers Types Sources
4338399 Beilstein Registry Number Beilstein
97322-87-7 CAS Registry Number ChemIDplus
97322-87-7 CAS Registry Number KEGG DRUG
Last Modified
22 February 2017