paroxetine hydrochloride (CHEBI:7944)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	paroxetine hydrochloride

ChEBI ID	CHEBI:7944

Definition	The hydrochloride salt of paroxetine. It is an antidepressant drug.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formulae

C19H20FNO3.ClH
C19H21ClFNO3

Net Charge

Average Mass

365.830

Monoisotopic Mass

365.11940

InChI

InChI=1S/C19H20FNO3.ClH/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;/h1-6,9,14,17,21H,7-8,10-12H2;1H/t14-,17-;/m0./s1

InChIKey

GELRVIPPMNMYGS-RVXRQPKJSA-N

SMILES

C=1(OC[C@H]2[C@](C=3C=CC(=CC3)F)(CCNC2)[H])C=C4C(OCO4)=CC1.[H]Cl

Roles Classification
Biological Role(s):	hepatotoxic agent A role played by a chemical compound exihibiting itself through the ability to induce damage to the liver in animals. P450 inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.

Application(s):	antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.

ChEBI Ontology
Outgoing	paroxetine hydrochloride (CHEBI:7944) has part paroxetinium(1+) (CHEBI:64197) paroxetine hydrochloride (CHEBI:7944) has role antidepressant (CHEBI:35469) paroxetine hydrochloride (CHEBI:7944) has role anxiolytic drug (CHEBI:35474) paroxetine hydrochloride (CHEBI:7944) has role hepatotoxic agent (CHEBI:50908) paroxetine hydrochloride (CHEBI:7944) has role P450 inhibitor (CHEBI:50183) paroxetine hydrochloride (CHEBI:7944) has role serotonin uptake inhibitor (CHEBI:50949) paroxetine hydrochloride (CHEBI:7944) is a hydrochloride (CHEBI:36807)

IUPAC Name

(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride

Synonyms	Sources
paroxetine HCl	ChemIDplus
paroxetine hydrochloride anhydrous	DrugBank

Registry Number	Type	Source
78246-49-8	CAS Registry Number	ChemIDplus

Last Modified

18 October 2019