CHEBI:7908 - pancuronium bromide

Main ChEBI Ontology Automatic Xrefs
ChEBI Name pancuronium bromide
ChEBI ID CHEBI:7908
Definition A bromide salt consisting of two bromide ions and one pancuronium dication.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C35H60Br2N2O4
Net Charge 0
Average Mass 732.67000
InChI InChI=1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1
InChIKey NPIJXCQZLFKBMV-YTGGZNJNSA-L
SMILES [Br-].[Br-].[H][C@@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@@]([H])(OC(C)=O)[C@H](C[C@@]34[H])[N+]3(C)CCCCC3)[C@@]1(C)C[C@@H]([C@H](C2)OC(C)=O)[N+]1(C)CCCCC1
Roles Classification
Biological Role(s): cholinergic antagonist
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
nicotinic antagonist
An antagonist at the nicotinic cholinergic receptor.
Application(s): muscle relaxant
A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis.
cholinergic antagonist
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
nicotinic antagonist
An antagonist at the nicotinic cholinergic receptor.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing pancuronium bromide (CHEBI:7908) has part pancuronium (CHEBI:7907)
pancuronium bromide (CHEBI:7908) has role cholinergic antagonist (CHEBI:48873)
pancuronium bromide (CHEBI:7908) has role muscle relaxant (CHEBI:51371)
pancuronium bromide (CHEBI:7908) has role nicotinic antagonist (CHEBI:48878)
pancuronium bromide (CHEBI:7908) is a bromide salt (CHEBI:22925)
IUPAC Name
3α,17β-diacetoxy-2β,16β-bis(1-methylpiperidinium-1-yl)-5α-androstane dibromide
INNs Sources
bromure de pancuronium ChemIDplus
bromuro de pancuronio ChemIDplus
pancuronii bromidum ChemIDplus
pancuronium bromide ChemIDplus
Synonyms Sources
(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2,16-bis(1-methylpiperidinium-1-yl)androstane dibromide IUPAC
2β,16β-dipiperidino-5α-androstane-3α,17β-diol diacetate dimethobromide ChemIDplus
3α,17β-diacetoxy-2β,16β-dipiperidino-5α-androstane dimethobromide ChemIDplus
Brand Names Sources
Mioblock DrugBank
Pavulon KEGG DRUG
Database Links Databases
D00492 KEGG DRUG
DB01337 DrugBank
View more database links
Registry Numbers Types Sources
15500-66-0 CAS Registry Number ChemIDplus
15500-66-0 CAS Registry Number KEGG DRUG
4226892 Reaxys Registry Number Reaxys
Last Modified
01 March 2011
General Comment
2011-03-01 A non-depolarizing curare-mimetic muscle relaxant, pancuronium bromide is used with general anaesthesia in surgery, and as an aid to intubation. It is used for euthenasia in the Netherlands.