CHEBI:77570 - tropisetron hydrochloride

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ChEBI Name tropisetron hydrochloride
ChEBI ID CHEBI:77570
Definition A hydrochloride obtained by combining equimolar amounts of tropisetron and hydrogen chloride.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C17H21ClN2O2
Net Charge 0
Average Mass 320.81400
Monoisotopic Mass 320.129
InChI InChI=1S/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,18H,6-9H2,1H3;1H/t11-,12+,13+;
InChIKey XIEGSJAEZIGKSA-LUNMCBQDSA-N
SMILES Cl.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1c[nH]c2ccccc12
Roles Classification
Biological Role(s): apoptosis inhibitor
Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms.
immunomodulator
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
nicotinic acetylcholine receptor agonist
An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
trypanocidal drug
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
antiemetic
A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
immunomodulator
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
nicotinic acetylcholine receptor agonist
An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
trypanocidal drug
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing tropisetron hydrochloride (CHEBI:77570) has part tropisetron(1+) (CHEBI:77571)
tropisetron hydrochloride (CHEBI:77570) has role anti-inflammatory agent (CHEBI:67079)
tropisetron hydrochloride (CHEBI:77570) has role antiemetic (CHEBI:50919)
tropisetron hydrochloride (CHEBI:77570) has role apoptosis inhibitor (CHEBI:68494)
tropisetron hydrochloride (CHEBI:77570) has role immunomodulator (CHEBI:50846)
tropisetron hydrochloride (CHEBI:77570) has role neuroprotective agent (CHEBI:63726)
tropisetron hydrochloride (CHEBI:77570) has role nicotinic acetylcholine receptor agonist (CHEBI:47958)
tropisetron hydrochloride (CHEBI:77570) has role serotonergic antagonist (CHEBI:48279)
tropisetron hydrochloride (CHEBI:77570) has role trypanocidal drug (CHEBI:36335)
tropisetron hydrochloride (CHEBI:77570) is a hydrochloride (CHEBI:36807)
IUPAC Names
(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate hydrochloride
(3-endo,8-syn)-3-[(1H-indol-3-ylcarbonyl)oxy]-8-methyl-8-azoniabicyclo[3.2.1]octane chloride
Synonyms Sources
Tropisetron HCl ChemIDplus
Tropisetron monohydrochloride ChemIDplus
Brand Name Source
Navoban KEGG DRUG
Database Links Databases
CN101278921 Patent
CN101444508 Patent
CN1682721 Patent
D02041 KEGG DRUG
Tropisetron Wikipedia
View more database links
Registry Numbers Types Sources
105826-92-4 CAS Registry Number ChemIDplus
105826-92-4 CAS Registry Number KEGG DRUG
11257467 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
12239690 PubMed citation Europe PMC
16086881 PubMed citation Europe PMC
17697550 PubMed citation Europe PMC
17876159 PubMed citation Europe PMC
21924384 PubMed citation Europe PMC
23391849 PubMed citation Europe PMC
Last Modified
04 March 2014