CHEBI:77053 - closantel

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ChEBI Name closantel
ChEBI ID CHEBI:77053
Definition A racemate comprising equimolar amounts of (R)- and (S)-clostanel. An anthelmintic, it is used (as the dihydrate of the sodium salt) in veterinary medicine for the treatment of fluke and nematode infections.
Stars This entity has been manually annotated by the ChEBI Team.
Roles Classification
Application(s): antinematodal drug
A substance used in the treatment or control of nematode infestations.
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ChEBI Ontology
Outgoing closantel (CHEBI:77053) has part (R)-closantel (CHEBI:77056)
closantel (CHEBI:77053) has part (S)-closantel (CHEBI:77057)
closantel (CHEBI:77053) has role antinematodal drug (CHEBI:35444)
closantel (CHEBI:77053) is a racemate (CHEBI:60911)
IUPAC Name
rac-N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide
INNs Sources
closantel WHO MedNet
closantel WHO MedNet
closantel WHO MedNet
closantelum WHO MedNet
Synonyms Sources
5'-chloro-α4-(p-chlorophenyl)-α4-cyano-3,5-diiodo-2',4'-salicyloxylidide ChemIDplus
R 31,520 ChemIDplus
R 31520 ChemIDplus
Brand Names Sources
Flukiver ChEBI
Seponver ChEBI
Database Links Databases
BE839481 Patent
D03567 KEGG DRUG
US4005218 Patent
View more database links
Registry Numbers Types Sources
57808-65-8 CAS Registry Number ChemIDplus
57808-65-8 CAS Registry Number KEGG DRUG
6249214 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
21247019 PubMed citation Europe PMC
22916226 PubMed citation Europe PMC
23992251 PubMed citation Europe PMC
3330516 PubMed citation Europe PMC
4054009 PubMed citation Europe PMC
7119989 PubMed citation Europe PMC
7571353 PubMed citation Europe PMC
9138034 PubMed citation Europe PMC
Last Modified
21 January 2014