CHEBI:7508 - framycetin

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ChEBI Name framycetin
ChEBI ID CHEBI:7508
Definition A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:44577
Supplier Information
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Formula C23H46N6O13
Net Charge 0
Average Mass 614.64370
Monoisotopic Mass 614.312
InChI InChI=1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
InChIKey PGBHMTALBVVCIT-VCIWKGPPSA-N
SMILES NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O
Roles Classification
Biological Role(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
allergen
A chemical compound which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
Escherichia coli metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
Application(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing framycetin (CHEBI:7508) has role Escherichia coli metabolite (CHEBI:76971)
framycetin (CHEBI:7508) has role allergen (CHEBI:50904)
framycetin (CHEBI:7508) has role antibacterial drug (CHEBI:36047)
framycetin (CHEBI:7508) is a aminoglycoside (CHEBI:47779)
framycetin (CHEBI:7508) is conjugate base of framycetin(6+) (CHEBI:87835)
Incoming neomycin (CHEBI:7507) has part framycetin (CHEBI:7508)
neomycin B sulfate (CHEBI:53636) has part framycetin (CHEBI:7508)
framycetin(6+) (CHEBI:87835) is conjugate acid of framycetin (CHEBI:7508)
IUPAC Name
(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-α-D-glucopyranoside
INNs Sources
framicetina ChemIDplus
framycetine ChemIDplus
framycetinum ChemIDplus
Synonyms Sources
Fradiomycin B KEGG COMPOUND
Framycetin ChemIDplus
Framycetin KEGG COMPOUND
Neomycin B KEGG COMPOUND
Database Links Databases
1896 DrugCentral
C01737 KEGG COMPOUND
CPD-14142 MetaCyc
D05140 KEGG DRUG
DB00452 DrugBank
LSM-5787 LINCS
NMY PDBeChem
View more database links
Registry Numbers Types Sources
101621 Reaxys Registry Number Reaxys
101621 Beilstein Registry Number Beilstein
119-04-0 CAS Registry Number KEGG COMPOUND
119-04-0 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
25129497 PubMed citation Europe PMC
25230155 PubMed citation Europe PMC
25450807 PubMed citation Europe PMC
25588492 PubMed citation Europe PMC
8548964 PubMed citation Europe PMC
Last Modified
22 February 2017