CHEBI:71320 - cyclopeptine

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ChEBI Name cyclopeptine
ChEBI ID CHEBI:71320
Definition A 1,4-benzodiazepinone that is 3,4-dihydro-1,4-benzodiazepine-2,5-dione substituted at position 4 by a methyl group and at position 3 by a benzyl group.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter KAX
Supplier Information
Download Molfile XML SDF
Formula C17H16N2O2
Net Charge 0
Average Mass 280.32110
Monoisotopic Mass 280.12118
InChI InChI=1S/C17H16N2O2/c1-19-15(11-12-7-3-2-4-8-12)16(20)18-14-10-6-5-9-13(14)17(19)21/h2-10,15H,11H2,1H3,(H,18,20)
InChIKey KSQNKZMAMGACTL-UHFFFAOYSA-N
SMILES CN1C(Cc2ccccc2)C(=O)Nc2ccccc2C1=O
Roles Classification
Biological Role(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
Application(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing cyclopeptine (CHEBI:71320) is a 1,4-benzodiazepinone (CHEBI:35500)
Incoming (S)-cyclopeptine (CHEBI:71333) is a cyclopeptine (CHEBI:71320)
IUPAC Name
3-benzyl-4-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione
Synonym Source
cyclopeptine UniProt
Registry Number Type Source
755945 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
11916664 PubMed citation SUBMITTER
2995633 PubMed citation Europe PMC
Last Modified
04 December 2012