CHEBI:70708 - dienogest

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ChEBI Name dienogest
ChEBI ID CHEBI:70708
Definition A steroid hormone that is 17β-hydroxy-3-oxoestra-4,9-diene substituted at position 17 by a cyanomethyl group. Used as an oral contraceptive.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C20H25NO2
Net Charge 0
Average Mass 311.41800
Monoisotopic Mass 311.189
InChI InChI=1S/C20H25NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-10H2,1H3/t17-,18+,19+,20-/m1/s1
InChIKey AZFLJNIPTRTECV-FUMNGEBKSA-N
SMILES [H][C@@]12CCC3=CC(=O)CCC3=C1CC[C@@]1(C)[C@@]2([H])CC[C@@]1(O)CC#N
Roles Classification
Biological Role(s): progesterone receptor agonist
A hormone agonist that binds to and activates progesterone receptors.
progestin
A synthetic progestogen.
hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via steroid hormone )
Application(s): synthetic oral contraceptive
An oral contraceptive which owes its effectiveness to synthetic preparation.
progesterone receptor agonist
A hormone agonist that binds to and activates progesterone receptors.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing dienogest (CHEBI:70708) has parent hydride estrane (CHEBI:23966)
dienogest (CHEBI:70708) has role progesterone receptor agonist (CHEBI:70709)
dienogest (CHEBI:70708) has role progestin (CHEBI:59826)
dienogest (CHEBI:70708) has role synthetic oral contraceptive (CHEBI:49326)
dienogest (CHEBI:70708) is a 17β-hydroxy steroid (CHEBI:35343)
dienogest (CHEBI:70708) is a 3-oxo-Δ4 steroid (CHEBI:47909)
dienogest (CHEBI:70708) is a aliphatic nitrile (CHEBI:80291)
dienogest (CHEBI:70708) is a steroid hormone (CHEBI:26764)
IUPAC Name
[(17β)-17-hydroxy-3-oxoestra-4,9-dien-17-yl]acetonitrile
INNs Sources
dienogest WHO MedNet
diénogest WHO MedNet
dienogest KEGG DRUG
dienogestum WHO MedNet
Synonyms Sources
(17-hydroxy-3-oxoestra-4,9-dien-17β-yl)acetonitrile ChEBI
17alpha-Cyanomethyl-17beta-hydroxyestra-4,9(10)-dien-3-one ChemIDplus
Database Links Databases
871 DrugCentral
D03799 KEGG DRUG
Dienogest Wikipedia
EP1935898 Patent
US2008214512 Patent
US2010298585 Patent
US6670350 Patent
WO2008116890 Patent
WO2011132045 Patent
View more database links
Registry Numbers Types Sources
5763925 Reaxys Registry Number Reaxys
65928-58-7 CAS Registry Number KEGG DRUG
65928-58-7 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017