florbetapir F-18 (CHEBI:66880)

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ChEBI Name	florbetapir F-18

ChEBI ID	CHEBI:66880

Definition	An aromatic ether consisting of a pyridine ring substituted at position 2 by a 2-{2-[2-(¹⁸F)fluoroethoxy]ethoxy}ethoxy group and at position 5 and a 2-(4-methylaminophenyl)vinyl group. A positron emission tomography imaging ligand for the detection of amyloid aggregation associated with Alzheimer disease.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C20H25[18F]N2O3

Net Charge

Average Mass

359.432

Monoisotopic Mass

359.18746

InChI

InChI=1S/C20H25FN2O3/c1-22-19-7-4-17(5-8-19)2-3-18-6-9-20(23-16-18)26-15-14-25-13-12-24-11-10-21/h2-9,16,22H,10-15H2,1H3/b3-2+/i21-1

InChIKey

YNDIAUKFXKEXSV-CRYLGTRXSA-N

SMILES

CNc1ccc(\C=C\c2ccc(OCCOCCOCC[18F])nc2)cc1

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Application(s):	radioactive imaging agent radiopharmaceutical Any pharmaceutical compound containing a radioisotope. (via (18)F radiopharmaceutical )

ChEBI Ontology
Outgoing	florbetapir F-18 (CHEBI:66880) has role radioactive imaging agent (CHEBI:37336) florbetapir F-18 (CHEBI:66880) is a ¹⁸F radiopharmaceutical (CHEBI:49127) florbetapir F-18 (CHEBI:66880) is a aromatic ether (CHEBI:35618) florbetapir F-18 (CHEBI:66880) is a organofluorine compound (CHEBI:37143) florbetapir F-18 (CHEBI:66880) is a pyridines (CHEBI:26421) florbetapir F-18 (CHEBI:66880) is a substituted aniline (CHEBI:48975)

IUPAC Name

4-{(E)-2-[6-(2-{2-[2-(¹⁸F)fluoroethoxy]ethoxy}ethoxy)pyridin-3-yl]ethenyl}-N-methylaniline

Synonym	Source
Florbetapir	ChemIDplus

Brand Name	Source
Amyvid	KEGG DRUG

Last Modified

22 February 2017