CHEBI:64144 - 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate

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ChEBI Name 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate
ChEBI ID CHEBI:64144
Definition A maleate salt obtained by reaction of 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine with one equivalent of maleic acid. A potent dopamine re-uptake inhibitor with a behavioral profile different from that of PCP and similar to that of cocaine.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C23H29NO4S
Net Charge 0
Average Mass 415.54600
Monoisotopic Mass 415.182
InChI InChI=1S/C19H25NS.C4H4O4/c1-5-11-19(12-6-1,20-13-7-2-8-14-20)18-15-16-9-3-4-10-17(16)21-18;5-3(6)1-2-4(7)8/h3-4,9-10,15H,1-2,5-8,11-14H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChIKey AMTYJSWZECGJOO-BTJKTKAUSA-N
SMILES OC(=O)\C=C/C(O)=O.C1CCN(CC1)C1(CCCCC1)c1cc2ccccc2s1
Roles Classification
Biological Role(s): dopamine uptake inhibitor
A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
Application(s): dopamine uptake inhibitor
A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
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ChEBI Ontology
Outgoing 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate (CHEBI:64144) has part 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidinium(1+) (CHEBI:64146)
1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate (CHEBI:64144) has role dopamine uptake inhibitor (CHEBI:51039)
1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate (CHEBI:64144) is a maleate salt (CHEBI:50221)
IUPAC Name
1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine (2Z)-but-2-enedioate
Synonyms Sources
1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidinium (2Z)-3-carboxyacrylate IUPAC
BTCP maleate ChEBI
Last Modified
09 March 2012